Nucleus instance segmentation from histopathology images suffers from the extremely laborious and expert-dependent annotation of nucleus instances. As a promising solution to this task, annotation-efficient deep learning paradigms have recently attracted much research interest, such as weakly-/semi-supervised learning, generative adversarial learning, etc. In this paper, we propose to formulate annotation-efficient nucleus instance segmentation from the perspective of few-shot learning (FSL). Our work was motivated by that, with the prosperity of computational pathology, an increasing number of fully-annotated datasets are publicly accessible, and we hope to leverage these external datasets to assist nucleus instance segmentation on the target dataset which only has very limited annotation. To achieve this goal, we adopt the meta-learning based FSL paradigm, which however has to be tailored in two substantial aspects before adapting to our task. First, since the novel classes may be inconsistent with those of the external dataset, we extend the basic definition of few-shot instance segmentation (FSIS) to generalized few-shot instance segmentation (GFSIS). Second, to cope with the intrinsic challenges of nucleus segmentation, including touching between adjacent cells, cellular heterogeneity, etc., we further introduce a structural guidance mechanism into the GFSIS network, finally leading to a unified Structurally-Guided Generalized Few-Shot Instance Segmentation (SGFSIS) framework. Extensive experiments on a couple of publicly accessible datasets demonstrate that, SGFSIS can outperform other annotation-efficient learning baselines, including semi-supervised learning, simple transfer learning, etc., with comparable performance to fully supervised learning with less than 5% annotations.
Scattering and attenuation of light in no-homogeneous imaging media or inconsistent light intensity will cause insufficient contrast and color distortion in the collected images, which limits the developments such as vision-driven smart urban, autonomous vehicles, and intelligent robots. In this paper, we propose an all-in-one scene recovery network via multi-knowledge integration (termed AoSRNet) to improve the visibility of imaging devices in typical low-visibility imaging scenes (e.g., haze, sand dust, and low light). It combines gamma correction (GC) and optimized linear stretching (OLS) to create the detail enhancement module (DEM) and color restoration module (CRM). Additionally, we suggest a multi-receptive field extraction module (MEM) to attenuate the loss of image texture details caused by GC nonlinear and OLS linear transformations. Finally, we refine the coarse features generated by DEM, CRM, and MEM through Encoder-Decoder to generate the final restored image. Comprehensive experimental results demonstrate the effectiveness and stability of AoSRNet compared to other state-of-the-art methods. The source code is available at \url{https://github.com/LouisYuxuLu/AoSRNet}.
Graph representation learning on vast datasets, like web data, has made significant strides. However, the associated computational and storage overheads raise concerns. In sight of this, Graph condensation (GCond) has been introduced to distill these large real datasets into a more concise yet information-rich synthetic graph. Despite acceleration efforts, existing GCond methods mainly grapple with efficiency, especially on expansive web data graphs. Hence, in this work, we pinpoint two major inefficiencies of current paradigms: (1) the concurrent updating of a vast parameter set, and (2) pronounced parameter redundancy. To counteract these two limitations correspondingly, we first (1) employ the Mean-Field variational approximation for convergence acceleration, and then (2) propose the objective of Gradient Information Bottleneck (GDIB) to prune redundancy. By incorporating the leading explanation techniques (e.g., GNNExplainer and GSAT) to instantiate the GDIB, our EXGC, the Efficient and eXplainable Graph Condensation method is proposed, which can markedly boost efficiency and inject explainability. Our extensive evaluations across eight datasets underscore EXGC's superiority and relevance. Code is available at https://github.com/MangoKiller/EXGC.
Machine learning models have demonstrated remarkable efficacy and efficiency in a wide range of stock forecasting tasks. However, the inherent challenges of data scarcity, including low signal-to-noise ratio (SNR) and data homogeneity, pose significant obstacles to accurate forecasting. To address this issue, we propose a novel approach that utilizes artificial intelligence-generated samples (AIGS) to enhance the training procedures. In our work, we introduce the Diffusion Model to generate stock factors with Transformer architecture (DiffsFormer). DiffsFormer is initially trained on a large-scale source domain, incorporating conditional guidance so as to capture global joint distribution. When presented with a specific downstream task, we employ DiffsFormer to augment the training procedure by editing existing samples. This editing step allows us to control the strength of the editing process, determining the extent to which the generated data deviates from the target domain. To evaluate the effectiveness of DiffsFormer augmented training, we conduct experiments on the CSI300 and CSI800 datasets, employing eight commonly used machine learning models. The proposed method achieves relative improvements of 7.2% and 27.8% in annualized return ratio for the respective datasets. Furthermore, we perform extensive experiments to gain insights into the functionality of DiffsFormer and its constituent components, elucidating how they address the challenges of data scarcity and enhance the overall model performance. Our research demonstrates the efficacy of leveraging AIGS and the DiffsFormer architecture to mitigate data scarcity in stock forecasting tasks.
This work introduces Weaver, our first family of large language models (LLMs) dedicated to content creation. Weaver is pre-trained on a carefully selected corpus that focuses on improving the writing capabilities of large language models. We then fine-tune Weaver for creative and professional writing purposes and align it to the preference of professional writers using a suit of novel methods for instruction data synthesis and LLM alignment, making it able to produce more human-like texts and follow more diverse instructions for content creation. The Weaver family consists of models of Weaver Mini (1.8B), Weaver Base (6B), Weaver Pro (14B), and Weaver Ultra (34B) sizes, suitable for different applications and can be dynamically dispatched by a routing agent according to query complexity to balance response quality and computation cost. Evaluation on a carefully curated benchmark for assessing the writing capabilities of LLMs shows Weaver models of all sizes outperform generalist LLMs several times larger than them. Notably, our most-capable Weaver Ultra model surpasses GPT-4, a state-of-the-art generalist LLM, on various writing scenarios, demonstrating the advantage of training specialized LLMs for writing purposes. Moreover, Weaver natively supports retrieval-augmented generation (RAG) and function calling (tool usage). We present various use cases of these abilities for improving AI-assisted writing systems, including integration of external knowledge bases, tools, or APIs, and providing personalized writing assistance. Furthermore, we discuss and summarize a guideline and best practices for pre-training and fine-tuning domain-specific LLMs.
Graph anomaly detection (GAD) is a challenging binary classification problem due to its different structural distribution between anomalies and normal nodes -- abnormal nodes are a minority, therefore holding high heterophily and low homophily compared to normal nodes. Furthermore, due to various time factors and the annotation preferences of human experts, the heterophily and homophily can change across training and testing data, which is called structural distribution shift (SDS) in this paper. The mainstream methods are built on graph neural networks (GNNs), benefiting the classification of normals from aggregating homophilous neighbors, yet ignoring the SDS issue for anomalies and suffering from poor generalization. This work solves the problem from a feature view. We observe that the degree of SDS varies between anomalies and normal nodes. Hence to address the issue, the key lies in resisting high heterophily for anomalies meanwhile benefiting the learning of normals from homophily. We tease out the anomaly features on which we constrain to mitigate the effect of heterophilous neighbors and make them invariant. We term our proposed framework as Graph Decomposition Network (GDN). Extensive experiments are conducted on two benchmark datasets, and the proposed framework achieves a remarkable performance boost in GAD, especially in an SDS environment where anomalies have largely different structural distribution across training and testing environments. Codes are open-sourced in https://github.com/blacksingular/wsdm_GDN.
Clinicians compare breast DCE-MRI after neoadjuvant chemotherapy (NAC) with pre-treatment scans to evaluate the response to NAC. Clinical evidence supports that accurate longitudinal deformable registration without deforming treated tumor regions is key to quantifying tumor changes. We propose a conditional pyramid registration network based on unsupervised keypoint detection and selective volume-preserving to quantify changes over time. In this approach, we extract the structural and the abnormal keypoints from DCE-MRI, apply the structural keypoints for the registration algorithm to restrict large deformation, and employ volume-preserving loss based on abnormal keypoints to keep the volume of the tumor unchanged after registration. We use a clinical dataset with 1630 MRI scans from 314 patients treated with NAC. The results demonstrate that our method registers with better performance and better volume preservation of the tumors. Furthermore, a local-global-combining biomarker based on the proposed method achieves high accuracy in pathological complete response (pCR) prediction, indicating that predictive information exists outside tumor regions. The biomarkers could potentially be used to avoid unnecessary surgeries for certain patients. It may be valuable for clinicians and/or computer systems to conduct follow-up tumor segmentation and response prediction on images registered by our method. Our code is available on \url{https://github.com/fiy2W/Treatment-aware-Longitudinal-Registration}.
High-quality imaging is crucial for ensuring safety supervision and intelligent deployment in fields like transportation and industry. It enables precise and detailed monitoring of operations, facilitating timely detection of potential hazards and efficient management. However, adverse weather conditions, such as atmospheric haziness and precipitation, can have a significant impact on image quality. When the atmosphere contains dense haze or water droplets, the incident light scatters, leading to degraded captured images. This degradation is evident in the form of image blur and reduced contrast, increasing the likelihood of incorrect assessments and interpretations by intelligent imaging systems (IIS). To address the challenge of restoring degraded images in hazy and rainy conditions, this paper proposes a novel multi-view knowledge-guided scene recovery network (termed MvKSR). Specifically, guided filtering is performed on the degraded image to separate high/low-frequency components. Subsequently, an en-decoder-based multi-view feature coarse extraction module (MCE) is used to coarsely extract features from different views of the degraded image. The multi-view feature fine fusion module (MFF) will learn and infer the restoration of degraded images through mixed supervision under different views. Additionally, we suggest an atrous residual block to handle global restoration and local repair in hazy/rainy/mixed scenes. Extensive experimental results demonstrate that MvKSR outperforms other state-of-the-art methods in terms of efficiency and stability for restoring degraded scenarios in IIS.
In the rapidly evolving domain of digital content generation, the focus has shifted from text-to-image (T2I) models to more advanced video diffusion models, notably text-to-video (T2V) and image-to-video (I2V). This paper addresses the intricate challenge posed by I2V: converting static images into dynamic, lifelike video sequences while preserving the original image fidelity. Traditional methods typically involve integrating entire images into diffusion processes or using pretrained encoders for cross attention. However, these approaches often necessitate altering the fundamental weights of T2I models, thereby restricting their reusability. We introduce a novel solution, namely I2V-Adapter, designed to overcome such limitations. Our approach preserves the structural integrity of T2I models and their inherent motion modules. The I2V-Adapter operates by processing noised video frames in parallel with the input image, utilizing a lightweight adapter module. This module acts as a bridge, efficiently linking the input to the model's self-attention mechanism, thus maintaining spatial details without requiring structural changes to the T2I model. Moreover, I2V-Adapter requires only a fraction of the parameters of conventional models and ensures compatibility with existing community-driven T2I models and controlling tools. Our experimental results demonstrate I2V-Adapter's capability to produce high-quality video outputs. This performance, coupled with its versatility and reduced need for trainable parameters, represents a substantial advancement in the field of AI-driven video generation, particularly for creative applications.