Abstract:We propose Process-Aware Policy Optimization (PAPO), a method that integrates process-level evaluation into Group Relative Policy Optimization (GRPO) through decoupled advantage normalization, to address two limitations of existing reward designs. Outcome reward models (ORM) evaluate only final-answer correctness, treating all correct responses identically regardless of reasoning quality, and gradually lose the advantage signal as groups become uniformly correct. Process reward models (PRM) offer richer supervision, but directly using PRM scores causes reward hacking, where models exploit verbosity to inflate scores while accuracy collapses. PAPO resolves both by composing the advantage from an outcome component Aout, derived from ORM and normalized over all responses, and a process component Aproc, derived from a rubric-based PRM and normalized exclusively among correct responses. This decoupled design ensures that Aout anchors training on correctness while Aproc differentiates reasoning quality without distorting the outcome signal. Experiments across multiple model scales and six benchmarks demonstrate that PAPO consistently outperforms ORM, reaching 51.3% vs.\ 46.3% on OlympiadBench while continuing to improve as ORM plateaus and declines.
Abstract:We introduce Intern-S1-Pro, the first one-trillion-parameter scientific multimodal foundation model. Scaling to this unprecedented size, the model delivers a comprehensive enhancement across both general and scientific domains. Beyond stronger reasoning and image-text understanding capabilities, its intelligence is augmented with advanced agent capabilities. Simultaneously, its scientific expertise has been vastly expanded to master over 100 specialized tasks across critical science fields, including chemistry, materials, life sciences, and earth sciences. Achieving this massive scale is made possible by the robust infrastructure support of XTuner and LMDeploy, which facilitates highly efficient Reinforcement Learning (RL) training at the 1-trillion parameter level while ensuring strict precision consistency between training and inference. By seamlessly integrating these advancements, Intern-S1-Pro further fortifies the fusion of general and specialized intelligence, working as a Specializable Generalist, demonstrating its position in the top tier of open-source models for general capabilities, while outperforming proprietary models in the depth of specialized scientific tasks.
Abstract:Earth Observation (EO) is essential for perceiving dynamic land surface changes, yet deploying autonomous EO in open environments is hindered by the immense diversity of multi-source data and heterogeneous tasks. While remote sensing agents have emerged to streamline EO workflows, existing tool-calling agents are confined to closed environments. They rely on pre-defined tools and are restricted to narrow scope, limiting their generalization to the diverse data and tasks. To overcome these limitations, we introduce OpenEarth-Agent, the first tool-creation agent framework tailored for open-environment EO. Rather than calling predefined tools, OpenEarth-Agent employs adaptive workflow planning and tool creation to generalize to unseen data and tasks. This adaptability is bolstered by an open-ended integration of multi-stage tools and cross-domain knowledge bases, enabling robust execution in the entire EO pipeline across multiple application domains. To comprehensively evaluate EO agents in open environments, we propose OpenEarth-Bench, a novel benchmark comprising 596 real-world, full-pipeline cases across seven application domains, explicitly designed to assess agents' adaptive planning and tool creation capabilities. Only essential pre-trained model tools are provided in this benchmark, devoid of any other predefined task-specific tools. Extensive experiments demonstrate that OpenEarth-Agent successfully masters full-pipeline EO across multiple domains in the open environment. Notably, on the cross-benchmark Earth-Bench, our tool-creating agent equipped with 6 essential pre-trained models achieves performance comparable to tool-calling agents relying on 104 specialized tools, and significantly outperforms them when provided with the complete toolset. In several cases, the created tools exhibit superior robustness to data anomalies compared to human-engineered counterparts.
Abstract:Inferring the physical mechanisms that govern earthquake sequences from indirect geophysical observations remains difficult, particularly across tectonically distinct environments where similar seismic patterns can reflect different underlying processes. Current interpretations rely heavily on the expert synthesis of catalogs, spatiotemporal statistics, and candidate physical models, limiting reproducibility and the systematic transfer of insight across settings. Here we present TRACE (Trans-perspective Reasoning and Automated Comprehensive Evaluator), a multi-agent system that combines large language model planning with formal seismological constraints to derive auditable, physically grounded mechanistic inference from raw observations. Applied to the 2019 Ridgecrest sequence, TRACE autonomously identifies stress-perturbation-induced delayed triggering, resolving the cascading interaction between the Mw 6.4 and Mw 7.1 mainshocks; in the Santorini-Kolumbo case, the system identifies a structurally guided intrusion model, distinguishing fault-channeled episodic migration from the continuous propagation expected in homogeneous crustal failure. By providing a generalizable logical infrastructure for interpreting heterogeneous seismic phenomena, TRACE advances the field from expert-dependent analysis toward knowledge-guided autonomous discovery in Earth sciences.
Abstract:Artificial intelligence has demonstrated remarkable capability in predicting scientific properties, yet scientific discovery remains an inherently physical, long-horizon pursuit governed by experimental cycles. Most current computational approaches are misaligned with this reality, framing discovery as isolated, task-specific predictions rather than continuous interaction with the physical world. Here, we argue for embodied science, a paradigm that reframes scientific discovery as a closed loop tightly coupling agentic reasoning with physical execution. We propose a unified Perception-Language-Action-Discovery (PLAD) framework, wherein embodied agents perceive experimental environments, reason over scientific knowledge, execute physical interventions, and internalize outcomes to drive subsequent exploration. By grounding computational reasoning in robust physical feedback, this approach bridges the gap between digital prediction and empirical validation, offering a roadmap for autonomous discovery systems in the life and chemical sciences.
Abstract:Long-range electrostatic and polarization interactions play a central role in molecular and condensed-phase systems, yet remain fundamentally incompatible with locality-based machine-learning interatomic potentials. Although modern SO(3)-equivariant neural potentials achieve high accuracy for short-range chemistry, they cannot represent the anisotropic, slowly decaying multipolar correlations governing realistic materials, while existing long-range extensions either break SO(3) equivariance or fail to maintain energy-force consistency. Here we introduce EquiEwald, a unified neural interatomic potential that embeds an Ewald-inspired reciprocal-space formulation within an irreducible SO(3)-equivariant framework. By performing equivariant message passing in reciprocal space through learned equivariant k-space filters and an equivariant inverse transform, EquiEwald captures anisotropic, tensorial long-range correlations without sacrificing physical consistency. Across periodic and aperiodic benchmarks, EquiEwald captures long-range electrostatic behavior consistent with ab initio reference data and consistently improves energy and force accuracy, data efficiency, and long-range extrapolation. These results establish EquiEwald as a physically principled paradigm for long-range-capable machine-learning interatomic potentials.
Abstract:Virtual cell models aim to enable in silico experimentation by predicting how cells respond to genetic, chemical, or cytokine perturbations from single-cell measurements. In practice, however, large-scale perturbation prediction remains constrained by three coupled bottlenecks: inefficient training and inference pipelines, unstable modeling in high-dimensional sparse expression space, and evaluation protocols that overemphasize reconstruction-like accuracy while underestimating biological fidelity. In this work we present a specialized large-scale foundation model SCALE for virtual cell perturbation prediction that addresses the above limitations jointly. First, we build a BioNeMo-based training and inference framework that substantially improves data throughput, distributed scalability, and deployment efficiency, yielding 12.51* speedup on pretrain and 1.29* on inference over the prior SOTA pipeline under matched system settings. Second, we formulate perturbation prediction as conditional transport and implement it with a set-aware flow architecture that couples LLaMA-based cellular encoding with endpoint-oriented supervision. This design yields more stable training and stronger recovery of perturbation effects. Third, we evaluate the model on Tahoe-100M using a rigorous cell-level protocol centered on biologically meaningful metrics rather than reconstruction alone. On this benchmark, our model improves PDCorr by 12.02% and DE Overlap by 10.66% over STATE. Together, these results suggest that advancing virtual cells requires not only better generative objectives, but also the co-design of scalable infrastructure, stable transport modeling, and biologically faithful evaluation.
Abstract:Understanding the world from distributed, partial viewpoints is a fundamental challenge for embodied multi-agent systems. Each agent perceives the environment through an ego-centric view that is often limited by occlusion and ambiguity. To study this problem, we introduce the Ego-to-World (E2W) benchmark, which evaluates a vision-language model's ability to fuse heterogeneous viewpoints across three tasks: (i) global counting, (ii) relational location reasoning, and (iii) action-oriented grasping that requires predicting view-specific image coordinates. To address this setting, we propose CoRL, a two-stage framework that combines Chain-of-Thought supervised fine-tuning with reinforcement learning using Group-Relative Policy Optimization. Its core component, the Cross-View Spatial Reward (CVSR), provides dense task-aligned feedback by linking reasoning steps to visual evidence, ensuring coherent cross-view entity resolution, and guiding the model toward correct final predictions. Experiments on E2W show that CoRL consistently surpasses strong proprietary and open-source baselines on both reasoning and perception-grounding metrics, while ablations further confirm the necessity of each CVSR component. Beyond that, CoRL generalizes to external spatial reasoning benchmarks and enables effective real-world multi-robot manipulation with calibrated multi-camera rigs, demonstrating cross-view localization and successful grasp-and-place execution. Together, E2W and CoRL provide a principled foundation for learning world-centric scene understanding from distributed, ego-centric observations, advancing collaborative embodied AI.
Abstract:Data assimilation (DA) combines model forecasts and observations to estimate the optimal state of the atmosphere with its uncertainty, providing initial conditions for weather prediction and reanalyses for climate research. Yet, existing traditional and machine-learning DA methods struggle to achieve accuracy, efficiency and uncertainty quantification simultaneously. Here, we propose HLOBA (Hybrid-Ensemble Latent Observation-Background Assimilation), a three-dimensional hybrid-ensemble DA method that operates in an atmospheric latent space learned via an autoencoder (AE). HLOBA maps both model forecasts and observations into a shared latent space via the AE encoder and an end-to-end Observation-to-Latent-space mapping network (O2Lnet), respectively, and fuses them through a Bayesian update with weights inferred from time-lagged ensemble forecasts. Both idealized and real-observation experiments demonstrate that HLOBA matches dynamically constrained four-dimensional DA methods in both analysis and forecast skill, while achieving end-to-end inference-level efficiency and theoretical flexibility applies to any forecasting model. Moreover, by exploiting the error decorrelation property of latent variables, HLOBA enables element-wise uncertainty estimates for its latent analysis and propagates them to model space via the decoder. Idealized experiments show that this uncertainty highlights large-error regions and captures their seasonal variability.
Abstract:The rapid proliferation of Claude agent skills has raised the central question of how to effectively leverage, manage, and scale the agent skill ecosystem. In this paper, we propose AgentSkillOS, the first principled framework for skill selection, orchestration, and ecosystem-level management. AgentSkillOS comprises two stages: (i) Manage Skills, which organizes skills into a capability tree via node-level recursive categorization for efficient discovery; and (ii) Solve Tasks, which retrieves, orchestrates, and executes multiple skills through DAG-based pipelines. To evaluate the agent's ability to invoke skills, we construct a benchmark of 30 artifact-rich tasks across five categories: data computation, document creation, motion video, visual design, and web interaction. We assess the quality of task outputs using LLM-based pairwise evaluation, and the results are aggregated via a Bradley-Terry model to produce unified quality scores. Experiments across three skill ecosystem scales (200 to 200K skills) show that tree-based retrieval effectively approximates oracle skill selection, and that DAG-based orchestration substantially outperforms native flat invocation even when given the identical skill set. Our findings confirm that structured composition is the key to unlocking skill potential. Our GitHub repository is available at:https://github.com/ynulihao/AgentSkillOS.