VisionFM: a Multi-Modal Multi-Task Vision Foundation Model for Generalist Ophthalmic Artificial Intelligence

We present VisionFM, a foundation model pre-trained with 3.4 million ophthalmic images from 560,457 individuals, covering a broad range of ophthalmic diseases, modalities, imaging devices, and demography. After pre-training, VisionFM provides a foundation to foster multiple ophthalmic artificial intelligence (AI) applications, such as disease screening and diagnosis, disease prognosis, subclassification of disease phenotype, and systemic biomarker and disease prediction, with each application enhanced with expert-level intelligence and accuracy. The generalist intelligence of VisionFM outperformed ophthalmologists with basic and intermediate levels in jointly diagnosing 12 common ophthalmic diseases. Evaluated on a new large-scale ophthalmic disease diagnosis benchmark database, as well as a new large-scale segmentation and detection benchmark database, VisionFM outperformed strong baseline deep neural networks. The ophthalmic image representations learned by VisionFM exhibited noteworthy explainability, and demonstrated strong generalizability to new ophthalmic modalities, disease spectrum, and imaging devices. As a foundation model, VisionFM has a large capacity to learn from diverse ophthalmic imaging data and disparate datasets. To be commensurate with this capacity, in addition to the real data used for pre-training, we also generated and leveraged synthetic ophthalmic imaging data. Experimental results revealed that synthetic data that passed visual Turing tests, can also enhance the representation learning capability of VisionFM, leading to substantial performance gains on downstream ophthalmic AI tasks. Beyond the ophthalmic AI applications developed, validated, and demonstrated in this work, substantial further applications can be achieved in an efficient and cost-effective manner using VisionFM as the foundation.

OneSeg: Self-learning and One-shot Learning based Single-slice Annotation for 3D Medical Image Segmentation

As deep learning methods continue to improve medical image segmentation performance, data annotation is still a big bottleneck due to the labor-intensive and time-consuming burden on medical experts, especially for 3D images. To significantly reduce annotation efforts while attaining competitive segmentation accuracy, we propose a self-learning and one-shot learning based framework for 3D medical image segmentation by annotating only one slice of each 3D image. Our approach takes two steps: (1) self-learning of a reconstruction network to learn semantic correspondence among 2D slices within 3D images, and (2) representative selection of single slices for one-shot manual annotation and propagating the annotated data with the well-trained reconstruction network. Extensive experiments verify that our new framework achieves comparable performance with less than 1% annotated data compared with fully supervised methods and generalizes well on several out-of-distribution testing sets.

The second multi-channel multi-party meeting transcription challenge (M2MeT) 2.0): A benchmark for speaker-attributed ASR

With the success of the first Multi-channel Multi-party Meeting Transcription challenge (M2MeT), the second M2MeT challenge (M2MeT 2.0) held in ASRU2023 particularly aims to tackle the complex task of speaker-attributed ASR (SA-ASR), which directly addresses the practical and challenging problem of "who spoke what at when" at typical meeting scenario. We particularly established two sub-tracks. 1) The fixed training condition sub-track, where the training data is constrained to predetermined datasets, but participants can use any open-source pre-trained model. 2) The open training condition sub-track, which allows for the use of all available data and models. In addition, we release a new 10-hour test set for challenge ranking. This paper provides an overview of the dataset, track settings, results, and analysis of submitted systems, as a benchmark to show the current state of speaker-attributed ASR.

Profile-Error-Tolerant Target-Speaker Voice Activity Detection

Target-Speaker Voice Activity Detection (TS-VAD) utilizes a set of speaker profiles alongside an input audio signal to perform speaker diarization. While its superiority over conventional methods has been demonstrated, the method can suffer from errors in speaker profiles, as those profiles are typically obtained by running a traditional clustering-based diarization method over the input signal. This paper proposes an extension to TS-VAD, called Profile-Error-Tolerant TS-VAD (PET-TSVAD), which is robust to such speaker profile errors. This is achieved by employing transformer-based TS-VAD that can handle a variable number of speakers and further introducing a set of additional pseudo-speaker profiles to handle speakers undetected during the first pass diarization. During training, we use speaker profiles estimated by multiple different clustering algorithms to reduce the mismatch between the training and testing conditions regarding speaker profiles. Experimental results show that PET-TSVAD consistently outperforms the existing TS-VAD method on both the VoxConverse and DIHARD-I datasets.

GCL: Gradient-Guided Contrastive Learning for Medical Image Segmentation with Multi-Perspective Meta Labels

Since annotating medical images for segmentation tasks commonly incurs expensive costs, it is highly desirable to design an annotation-efficient method to alleviate the annotation burden. Recently, contrastive learning has exhibited a great potential in learning robust representations to boost downstream tasks with limited labels. In medical imaging scenarios, ready-made meta labels (i.e., specific attribute information of medical images) inherently reveal semantic relationships among images, which have been used to define positive pairs in previous work. However, the multi-perspective semantics revealed by various meta labels are usually incompatible and can incur intractable "semantic contradiction" when combining different meta labels. In this paper, we tackle the issue of "semantic contradiction" in a gradient-guided manner using our proposed Gradient Mitigator method, which systematically unifies multi-perspective meta labels to enable a pre-trained model to attain a better high-level semantic recognition ability. Moreover, we emphasize that the fine-grained discrimination ability is vital for segmentation-oriented pre-training, and develop a novel method called Gradient Filter to dynamically screen pixel pairs with the most discriminating power based on the magnitude of gradients. Comprehensive experiments on four medical image segmentation datasets verify that our new method GCL: (1) learns informative image representations and considerably boosts segmentation performance with limited labels, and (2) shows promising generalizability on out-of-distribution datasets.

t-SOT FNT: Streaming Multi-talker ASR with Text-only Domain Adaptation Capability

Token-level serialized output training (t-SOT) was recently proposed to address the challenge of streaming multi-talker automatic speech recognition (ASR). T-SOT effectively handles overlapped speech by representing multi-talker transcriptions as a single token stream with $\langle \text{cc}\rangle$ symbols interspersed. However, the use of a naive neural transducer architecture significantly constrained its applicability for text-only adaptation. To overcome this limitation, we propose a novel t-SOT model structure that incorporates the idea of factorized neural transducers (FNT). The proposed method separates a language model (LM) from the transducer's predictor and handles the unnatural token order resulting from the use of $\langle \text{cc}\rangle$ symbols in t-SOT. We achieve this by maintaining multiple hidden states and introducing special handling of the $\langle \text{cc}\rangle$ tokens within the LM. The proposed t-SOT FNT model achieves comparable performance to the original t-SOT model while retaining the ability to reduce word error rate (WER) on both single and multi-talker datasets through text-only adaptation.

Can Large Language Models Discern Evidence for Scientific Hypotheses? Case Studies in the Social Sciences

Hypothesis formulation and testing are central to empirical research. A strong hypothesis is a best guess based on existing evidence and informed by a comprehensive view of relevant literature. However, with exponential increase in the number of scientific articles published annually, manual aggregation and synthesis of evidence related to a given hypothesis is a challenge. Our work explores the ability of current large language models (LLMs) to discern evidence in support or refute of specific hypotheses based on the text of scientific abstracts. We share a novel dataset for the task of scientific hypothesis evidencing using community-driven annotations of studies in the social sciences. We compare the performance of LLMs to several state-of-the-art benchmarks and highlight opportunities for future research in this area. The dataset is available at https://github.com/Sai90000/ScientificHypothesisEvidencing.git

Bilingual Streaming ASR with Grapheme units and Auxiliary Monolingual Loss

We introduce a bilingual solution to support English as secondary locale for most primary locales in hybrid automatic speech recognition (ASR) settings. Our key developments constitute: (a) pronunciation lexicon with grapheme units instead of phone units, (b) a fully bilingual alignment model and subsequently bilingual streaming transformer model, (c) a parallel encoder structure with language identification (LID) loss, (d) parallel encoder with an auxiliary loss for monolingual projections. We conclude that in comparison to LID loss, our proposed auxiliary loss is superior in specializing the parallel encoders to respective monolingual locales, and that contributes to stronger bilingual learning. We evaluate our work on large-scale training and test tasks for bilingual Spanish (ES) and bilingual Italian (IT) applications. Our bilingual models demonstrate strong English code-mixing capability. In particular, the bilingual IT model improves the word error rate (WER) for a code-mix IT task from 46.5% to 13.8%, while also achieving a close parity (9.6%) with the monolingual IT model (9.5%) over IT tests.

Ord2Seq: Regarding Ordinal Regression as Label Sequence Prediction

Ordinal regression refers to classifying object instances into ordinal categories. It has been widely studied in many scenarios, such as medical disease grading, movie rating, etc. Known methods focused only on learning inter-class ordinal relationships, but still incur limitations in distinguishing adjacent categories thus far. In this paper, we propose a simple sequence prediction framework for ordinal regression called Ord2Seq, which, for the first time, transforms each ordinal category label into a special label sequence and thus regards an ordinal regression task as a sequence prediction process. In this way, we decompose an ordinal regression task into a series of recursive binary classification steps, so as to subtly distinguish adjacent categories. Comprehensive experiments show the effectiveness of distinguishing adjacent categories for performance improvement and our new approach exceeds state-of-the-art performances in four different scenarios. Codes are available at https://github.com/wjh892521292/Ord2Seq.

Ord2Seq: Regard Ordinal Regression as Label Sequence Prediction

Ordinal regression refers to classifying object instances into ordinal categories. It has been widely studied in many scenarios, such as medical disease grading, movie rating, etc. Known methods focused only on learning inter-class ordinal relationships, but still incur limitations in distinguishing adjacent categories thus far. In this paper, we propose a simple sequence prediction framework for ordinal regression called Ord2Seq, which, for the first time, transforms each ordinal category label into a special label sequence and thus regards an ordinal regression task as a sequence prediction process. In this way, we decompose an ordinal regression task into a series of recursive binary classification steps, so as to subtly distinguish adjacent categories. Comprehensive experiments show the effectiveness of distinguishing adjacent categories for performance improvement and our new approach exceeds state-of-the-art performances in four different scenarios. Codes will be available upon acceptance.