Abstract:Generative recommendation formulates next-item prediction as conditional autoregressive generation over discrete Semantic IDs, enabling end-to-end recommendation over large-scale item spaces. However, most existing methods follow a history-as-context paradigm that repeatedly reconstructs user preference from behavior history while discarding system-side recommendation decisions after each request. This creates an asymmetric memory: the system remembers what the user has done, but not what it has previously recommended or learned from the resulting feedback. Consequently, useful preference-validation signals, potential negative evidence, and historical exploration information cannot be directly reused across requests. To address these limitations, we propose LoopMemGR, a closed-loop recommendation experience memory framework for generative recommendation. In addition to the conventional behavior log, LoopMemGR maintains a recommendation experience log that records past recommendation--feedback trajectories. It extracts request-relevant evidence through three complementary views: the recency view captures short-term interaction dynamics, the frequency view summarizes recurring recommendation patterns, and the global view distills transferable regularities shared across users. These signals are compressed into a fixed number of experience tokens to condition the generative backbone under a bounded input budget. Extensive experiments on an industrial Taobao dataset demonstrate the effectiveness of closed-loop experience accumulation and multi-view experience extraction.
Abstract:Medical image fusion aims to integrate complementary information from diverse imaging modalities to support clinical diagnosis. Existing methods typically apply uniform fusion rules globally, lacking a deep understanding of diagnostic intents and pathological structures. To address these limitations, we propose MIND, a Multimodal Intent-Driven Network via Diffusion Transformers (DiTs) for medical image fusion. Specifically, we utilize BioMedGPT to generate intent-driven fusion texts from source images, guiding the fusion process with pathology-aware diagnostic intents. To combat the loss of 2D spatial continuity caused by 1D sequence flattening in DiTs, we design a Multi-scale Latent Adapter. This module explicitly extracts source image features before serialization, injecting them into the network via strict dimensional alignment to effectively supplement image features. To resolve the semantic shift caused by decoupling image outputs from diagnostic intents, we design a medical semantic consistency loss. This loss ensures deep semantic locking between fused images and fusion texts while maintaining the stability of the underlying physical manifold reconstruction. Comprehensive experiments on the Harvard, BraTS, and GFP datasets reveal that MIND delivers superior fusion quality, significantly improves downstream brain tumor segmentation accuracy, and enables flexible interactive fusion, holding significant promise for intent-driven intelligent clinical decision support systems.
Abstract:While data synthesis for large language models (LLMs) is prevalent, it primarily targets domains with verifiable answers, overlooking open-ended humanities and social sciences (HSS), where nuanced quality judgments matter more than objective correctness. This makes preference alignment a natural paradigm for broad HSS tasks. Yet existing methods are either costly or not tailored to broad HSS disciplines. We thus propose BridgeAlign, among the first preference-alignment pipelines for broad HSS disciplines, with three phases: i) Seed Curation: curating HSS seed documents from web corpora via heuristic/LLM-based filtering and text refinement; ii) Preference Data Synthesis: generating preference triplets via persona-based instruction inversion with Q&A consistency checks; iii) Preference Optimization: moving beyond naive human-vs-model heuristics by first grounding preferences in HSS quality rubric, then generating transitional responses via controlled quality degradation to form near-boundary preference pairs for finer-grained quality discrimination. Aligning over 210k synthetic preference samples, BridgeAlign enables Qwen3-8B to achieve the best average across 17 benchmarks against 11 strong baselines; importantly, leading on both human-preference and knowledge-based capabilities at once, with no trade-off between them, as supported by extensive experiments and contextualized by existing theories.
Abstract:Sequential recommenders are commonly trained with one-hot next-item labels under a causal (prefix-only) objective aligned with inference. While deployment-compatible, this supervision offers little insight into relative preferences among non-target items. Yet logged interaction sequences contain an additional supervisory source: interactions following the target often reveal how user intent evolves, making the target easier to interpret. We treat these future interactions as training-only privileged information, available during learning but not at inference. This raises a natural question: can future interactions provide richer supervision while keeping training aligned with inference-time prediction? We propose Privileged Self-Distillation (PSD), a framework that separates learning-time information from inference-time information. PSD applies two attention masks to the same backbone: a future-aware view yields a privileged teacher distribution conditioned on past and future interactions, while a prefix-only view yields the student distribution used for deployment. Distilling the privileged distribution converts future interactions into training-only supervision rather than inference-time inputs. Since both views share a backbone, the teacher's advantage is purely informational, not architectural, removing the need for a separately pretrained teacher and letting its supervision adapt as the student evolves. PSD further uses an advantage-reachability gate to focus distillation on teacher signals likely supported by the observed prefix, along with a momentum-averaged teacher for stable targets. The framework is optimized end-to-end in a single stage, leaving the deployed model and inference cost unchanged. Experiments across public benchmarks and diverse backbones show consistent improvements.
Abstract:Generative recommendation tokenizes items as discrete Semantic IDs (SIDs) and autoregressively generates target items from users' historical SID sequences. Although existing SIDs incorporate multimodal and structured information, they are typically statically assigned and independent of the current interaction context. In industrial scenarios, each behavior also contains heterogeneous attributes, such as category, brand, price, behavior type, and timestamp. Fully expanding these features greatly increases the input length, while directly compressing them into a single representation may prematurely discard context-relevant information. We propose \textbf{SPARC}, \uline{\textbf{S}}equence-aware \uline{\textbf{P}}rogressive \uline{\textbf{A}}ttribute \uline{\textbf{R}}outing and \uline{\textbf{C}}ompression Framework for Generative recommendation. SPARC first models the sequential dependencies of each field type to obtain context-aware field representations. It then routes the original, contextual, and identity representations of different fields into multiple slots to preserve complementary information under a fixed capacity. Finally, lightweight cross-item interaction integrates the intermediate tokens and compresses each historical item into a single token. Following the principle of contextualizing before compression, SPARC enriches user-history representations without increasing the input length of the generative backbone. Experiments on industrial Taobao and public Amazon datasets demonstrate that SPARC outperforms strong conventional and generative baselines. Further comparisons with static compression variants show that the improvement of SPARC comes from context-conditioned information retention rather than merely increasing the expressiveness of the compression module.
Abstract:Ordinal regression is widely used in scenarios where labels are discrete yet inherently ordered. In practice, however, ordinal labels are often obtained by discretizing underlying continuous semantics through subjective human judgment, resulting in ambiguous boundaries and annotation noise. Such uncertainty challenges existing methods that rely on fixed supervision targets, which may reinforce biased ordering under subjective annotations. To address this limitation, we propose D3O, a dynamic distribution distillation framework that replaces static supervision with training-driven evolution of ordinal label distributions via self-distillation. Specifically, we introduce a contrastive ordinal-aware label enhancement module that leverages vision-language alignment to recover refined label distributions capturing both inter-class ambiguity and instance-level uncertainty. Furthermore, we design a CDF-based cross-layer interaction distillation mechanism to propagate cumulative ordinal structure across network hierarchy, ensuring consistent ordinal geometry in intermediate representations. Extensive experiments on four general ordinal regression tasks demonstrate that our proposed D3O consistently outperforms existing approaches, particularly under severe class imbalance and noisy supervision. These results highlight the effectiveness of dynamic supervision in learning robust ordinal representations beyond fixed targets. The code will be publicly available.
Abstract:Neurological disorders are a leading cause of global disability and are increasingly linked to environmental chemical exposures. Yet neurotoxicity assessment still relies on hand-scored morphological readouts that are subjective and poorly predictive of behavioral outcomes. Caenorhabditis elegans provides a genetically tractable, 3R-compliant alternative, but quantifying neuronal phenotypes from confocal microscopy at scale remains computationally challenging: existing vision foundation models, trained on natural or radiological images, cannot resolve the sparse signals and multi-scale lesions of neuronal imaging. Here, we introduce a dedicated self-supervised vision model for C. elegans dopaminergic neurons, together with CeNeuMorph, a multi-grained confocal benchmark of 27,117 annotated images. Specifically, moving beyond standard Masked Autoencoders, we propose a scale-adaptive masked image modeling strategy that jointly learns representations across resolutions and patch sizes under a fixed token budget. By decoupling structural semantic learning from rigid grid constraints, the model effectively resolves the full spectrum of neurodegenerative lesions - ranging from fine dendritic beading to gross soma shrinkage - within a tractable computational framework. Finally, our model surpasses both generalist and biomedical foundation models across classification, segmentation and detection tasks. Fusing visual features with morphological descriptors enables prediction of dopamine-dependent behavioral deficits ($R^2=0.498$). Screening 180 agrochemicals, we identify the benzimidazole moiety as a previously unrecognized determinant of dopaminergic neurotoxicity. Together, the work demonstrates how scale-adaptive self-supervised learning can connect morphology to function for a scalable alternative to mammalian in vivo models for neurotoxicity assessment and drug discovery.
Abstract:Large language models (LLMs) are transforming recommender systems from matching co-occurrence patterns in historical behavior toward reasoning about the intent that drives it. RecGPT-V1 pioneered this paradigm on Taobao by centering user understanding, and RecGPT-V2 scaled it via coordinated multi-agent reasoning; both are deployed in production with consistent gains in user experience and commercial outcomes. However, operating RecGPT at scale reveals three challenges: (1) stateless behavior modeling, where each request reprocesses full user history, wasting computation and discarding prior analysis; (2) a tag-to-item information bottleneck, where natural-language tags form a lossy channel between user understanding and item grounding; and (3) inefficient explicit reasoning, whose lengthy chain-of-thought incurs untenable latency and compute overhead. We present RecGPT-V3, a stateful, hybrid-modal recommender that reasons over natural language for open-world knowledge and Semantic IDs (SIDs) for concrete item grounding. A Memory Hub maintains structured, continually evolving user memory that distills long-horizon behavior into condensed units, cutting user-modeling computation by 55.8%. A Hybrid-modal Foundation Model allows the LLM jointly reason over text tags and SIDs, opening a high-bandwidth channel into the item space. Latent Intent Reasoning internalizes verbose rationales into compact learnable latent tokens that remain decodable into readable explanations, lowering output token cost by 200x. Deployed in Taobao's "Guess What You Like" feed, RecGPT-V3 achieves consistent gains in large-scale online A/B tests: IPV +1.28%, CTR +1.00%, TC +1.97%, GMV +3.97%, while cutting end-to-end serving resource consumption by 52.4%.
Abstract:Surgical vision-language foundation models typically adopt educational materials, such as surgical lecture videos, to transfer surgical knowledge encoded in language into visual representations. These knowledge are multi-dimensional and hierarchical: fine-grained action cues appear in narration, mid-level key steps are summarized in subsection headings, and global procedural context, such as patient history and surgical strategy, is described in abstract texts. Prior work largely collapses these heterogeneous signals into a single flat embedding space, implicitly assuming independence across hierarchy levels. However, this is suboptimal because it ignores cross-level semantic containment, e.g., actions belong to steps, steps compose phases, weakens long-range dependency modeling. To this end, we propose a hyperbolic surgical video-language pre-training framework that explicitly preserves the hierarchical structure by mitigating structural false negatives induced by procedural context and enforcing semantic consistency between parent phases and their constituent child steps. Extensive experiments on multiple surgical benchmarks show consistent gains in zero- and few-shot phase recognition across procedures and institutions.
Abstract:Open-set semi-supervised learning aims to leverage unlabeled data that may contain out-of-distribution outliers while maintaining performance on in-distribution classes. Existing methods mainly follow two paradigms: filtering suspicious samples or incorporating unlabeled objectives with soft weighting. We argue that both face a common trade-off: aggressive filtering can discard informative but hard ID samples, whereas utilization can introduce auxiliary gradients that conflict with supervised learning when pseudo labels are wrong. We therefore shift the focus from sample selection to gradient-level control. We propose \textit{Geometric Gradient Rectification} (GGR), a plug-in framework that uses the supervised gradient as an anchor and projects conflicting auxiliary gradients onto an admissible region in gradient space. This makes the applied auxiliary update first-order non-opposing within the rectified coordinate block while preserving orthogonal components that may still carry useful representation signals. We further extend GGR with subspace-aware rectification to stabilize the anchor under noisy mini-batch gradients. Experiments on CIFAR and ImageNet benchmarks show that GGR improves representative OSSL baselines in most settings and yields gains in both closed-set generalization and open-set robustness. Code will be available at https://github.com/JiaheChen2002/GGR.