Recent research in the field of multimodal machine translation (MMT) has indicated that the visual modality is either dispensable or offers only marginal advantages. However, most of these conclusions are drawn from the analysis of experimental results based on a limited set of bilingual sentence-image pairs, such as Multi30k. In these kinds of datasets, the content of one bilingual parallel sentence pair must be well represented by a manually annotated image, which is different from the real-world translation scenario. In this work, we adhere to the universal multimodal machine translation framework proposed by Tang et al. (2022). This approach allows us to delve into the impact of the visual modality on translation efficacy by leveraging real-world translation datasets. Through a comprehensive exploration via probing tasks, we find that the visual modality proves advantageous for the majority of authentic translation datasets. Notably, the translation performance primarily hinges on the alignment and coherence between textual and visual contents. Furthermore, our results suggest that visual information serves a supplementary role in multimodal translation and can be substituted.
Real-time 6 DOF localization of bronchoscopes is crucial for enhancing intervention quality. However, current vision-based technologies struggle to balance between generalization to unseen data and computational speed. In this study, we propose a Depth-based Dual-Loop framework for real-time Visually Navigated Bronchoscopy (DD-VNB) that can generalize across patient cases without the need of re-training. The DD-VNB framework integrates two key modules: depth estimation and dual-loop localization. To address the domain gap among patients, we propose a knowledge-embedded depth estimation network that maps endoscope frames to depth, ensuring generalization by eliminating patient-specific textures. The network embeds view synthesis knowledge into a cycle adversarial architecture for scale-constrained monocular depth estimation. For real-time performance, our localization module embeds a fast ego-motion estimation network into the loop of depth registration. The ego-motion inference network estimates the pose change of the bronchoscope in high frequency while depth registration against the pre-operative 3D model provides absolute pose periodically. Specifically, the relative pose changes are fed into the registration process as the initial guess to boost its accuracy and speed. Experiments on phantom and in-vivo data from patients demonstrate the effectiveness of our framework: 1) monocular depth estimation outperforms SOTA, 2) localization achieves an accuracy of Absolute Tracking Error (ATE) of 4.7 $\pm$ 3.17 mm in phantom and 6.49 $\pm$ 3.88 mm in patient data, 3) with a frame-rate approaching video capture speed, 4) without the necessity of case-wise network retraining. The framework's superior speed and accuracy demonstrate its promising clinical potential for real-time bronchoscopic navigation.
A novel near-field transmission framework is proposed for dynamic metasurface antenna (DMA)-enabled non-orthogonal multiple access (NOMA) networks. The base station (BS) exploits the hybrid beamforming to communicate with multiple near users (NUs) and far users (FUs) using the NOMA principle. Based on this framework, two novel beamforming schemes are proposed. 1) For the case of the grouped users distributed in the same direction, a beam-steering scheme is developed. The metric of beam pattern error (BPE) is introduced for the characterization of the gap between the hybrid beamformers and the desired ideal beamformers, where a two-layer algorithm is proposed to minimize BPE by optimizing hybrid beamformers. Then, the optimal power allocation strategy is obtained to maximize the sum achievable rate of the network. 2) For the case of users randomly distributed, a beam-splitting scheme is proposed, where two sub-beamformers are extracted from the single beamformer to serve different users in the same group. An alternating optimization (AO) algorithm is proposed for hybrid beamformer optimization, and the optimal power allocation is also derived. Numerical results validate that: 1) the proposed beamforming schemes exhibit superior performance compared with the existing imperfect-resolution-based beamforming scheme; 2) the communication rate of the proposed transmission framework is sensitive to the imperfect distance knowledge of NUs but not to that of FUs.
We present and discuss the results of a qualitative analysis of visual representations from images. We labeled each image's essential stimuli, the removal of which would render a visualization uninterpretable. As a result, we derive a typology of 10 visualization types of defined groups. We describe the typology derivation process in which we engaged. The resulting typology and image analysis can serve a number of purposes: enabling researchers to study the evolution of the community and its research output over time, facilitating the categorization of visualization images for the purpose of research and teaching, allowing researchers and practitioners to identify visual design styles to further align the quantification of any visual information processor, be that a person or an algorithm observer, and it facilitates a discussion of standardization in visualization. In addition to the visualization typology from images, we provide a dataset of 6,833 tagged images and an online tool that can be used to explore and analyze the large set of labeled images. The tool and data set enable scholars to closely examine the diverse visual designs used and how they are published and communicated in our community. A pre-registration, a free copy of this paper, and all supplemental materials are available via osf.io/dxjwt.
Bronchoscopy plays a significant role in the early diagnosis and treatment of lung diseases. This process demands physicians to maneuver the flexible endoscope for reaching distal lesions, particularly requiring substantial expertise when examining the airways of the upper lung lobe. With the development of artificial intelligence and robotics, reinforcement learning (RL) method has been applied to the manipulation of interventional surgical robots. However, unlike human physicians who utilize multimodal information, most of the current RL methods rely on a single modality, limiting their performance. In this paper, we propose BronchoCopilot, a multimodal RL agent designed to acquire manipulation skills for autonomous bronchoscopy. BronchoCopilot specifically integrates images from the bronchoscope camera and estimated robot poses, aiming for a higher success rate within challenging airway environment. We employ auxiliary reconstruction tasks to compress multimodal data and utilize attention mechanisms to achieve an efficient latent representation of this data, serving as input for the RL module. This framework adopts a stepwise training and fine-tuning approach to mitigate the challenges of training difficulty. Our evaluation in the realistic simulation environment reveals that BronchoCopilot, by effectively harnessing multimodal information, attains a success rate of approximately 90\% in fifth generation airways with consistent movements. Additionally, it demonstrates a robust capacity to adapt to diverse cases.
Traditional rigid endoscopes have challenges in flexibly treating tumors located deep in the brain, and low operability and fixed viewing angles limit its development. This study introduces a novel dual-segment flexible robotic endoscope MicroNeuro, designed to perform biopsies with dexterous surgical manipulation deep in the brain. Taking into account the uncertainty of the control model, an image-based visual servoing with online robot Jacobian estimation has been implemented to enhance motion accuracy. Furthermore, the application of model predictive control with constraints significantly bolsters the flexible robot's ability to adaptively track mobile objects and resist external interference. Experimental results underscore that the proposed control system enhances motion stability and precision. Phantom testing substantiates its considerable potential for deployment in neurosurgery.
Localizing the bronchoscope in real time is essential for ensuring intervention quality. However, most existing methods struggle to balance between speed and generalization. To address these challenges, we present BronchoTrack, an innovative real-time framework for accurate branch-level localization, encompassing lumen detection, tracking, and airway association.To achieve real-time performance, we employ a benchmark lightweight detector for efficient lumen detection. We are the first to introduce multi-object tracking to bronchoscopic localization, mitigating temporal confusion in lumen identification caused by rapid bronchoscope movement and complex airway structures. To ensure generalization across patient cases, we propose a training-free detection-airway association method based on a semantic airway graph that encodes the hierarchy of bronchial tree structures.Experiments on nine patient datasets demonstrate BronchoTrack's localization accuracy of 85.64 \%, while accessing up to the 4th generation of airways.Furthermore, we tested BronchoTrack in an in-vivo animal study using a porcine model, where it successfully localized the bronchoscope into the 8th generation airway.Experimental evaluation underscores BronchoTrack's real-time performance in both satisfying accuracy and generalization, demonstrating its potential for clinical applications.
Controllable layout generation refers to the process of creating a plausible visual arrangement of elements within a graphic design (e.g., document and web designs) with constraints representing design intentions. Although recent diffusion-based models have achieved state-of-the-art FID scores, they tend to exhibit more pronounced misalignment compared to earlier transformer-based models. In this work, we propose the $\textbf{LA}$yout $\textbf{C}$onstraint diffusion mod$\textbf{E}$l (LACE), a unified model to handle a broad range of layout generation tasks, such as arranging elements with specified attributes and refining or completing a coarse layout design. The model is based on continuous diffusion models. Compared with existing methods that use discrete diffusion models, continuous state-space design can enable the incorporation of differentiable aesthetic constraint functions in training. For conditional generation, we introduce conditions via masked input. Extensive experiment results show that LACE produces high-quality layouts and outperforms existing state-of-the-art baselines.