Harnessing Multi-Role Capabilities of Large Language Models for Open-Domain Question Answering

Open-domain question answering (ODQA) has emerged as a pivotal research spotlight in information systems. Existing methods follow two main paradigms to collect evidence: (1) The \textit{retrieve-then-read} paradigm retrieves pertinent documents from an external corpus; and (2) the \textit{generate-then-read} paradigm employs large language models (LLMs) to generate relevant documents. However, neither can fully address multifaceted requirements for evidence. To this end, we propose LLMQA, a generalized framework that formulates the ODQA process into three basic steps: query expansion, document selection, and answer generation, combining the superiority of both retrieval-based and generation-based evidence. Since LLMs exhibit their excellent capabilities to accomplish various tasks, we instruct LLMs to play multiple roles as generators, rerankers, and evaluators within our framework, integrating them to collaborate in the ODQA process. Furthermore, we introduce a novel prompt optimization algorithm to refine role-playing prompts and steer LLMs to produce higher-quality evidence and answers. Extensive experimental results on widely used benchmarks (NQ, WebQ, and TriviaQA) demonstrate that LLMQA achieves the best performance in terms of both answer accuracy and evidence quality, showcasing its potential for advancing ODQA research and applications.

Leveraging Biomolecule and Natural Language through Multi-Modal Learning: A Survey

The integration of biomolecular modeling with natural language (BL) has emerged as a promising interdisciplinary area at the intersection of artificial intelligence, chemistry and biology. This approach leverages the rich, multifaceted descriptions of biomolecules contained within textual data sources to enhance our fundamental understanding and enable downstream computational tasks such as biomolecule property prediction. The fusion of the nuanced narratives expressed through natural language with the structural and functional specifics of biomolecules described via various molecular modeling techniques opens new avenues for comprehensively representing and analyzing biomolecules. By incorporating the contextual language data that surrounds biomolecules into their modeling, BL aims to capture a holistic view encompassing both the symbolic qualities conveyed through language as well as quantitative structural characteristics. In this review, we provide an extensive analysis of recent advancements achieved through cross modeling of biomolecules and natural language. (1) We begin by outlining the technical representations of biomolecules employed, including sequences, 2D graphs, and 3D structures. (2) We then examine in depth the rationale and key objectives underlying effective multi-modal integration of language and molecular data sources. (3) We subsequently survey the practical applications enabled to date in this developing research area. (4) We also compile and summarize the available resources and datasets to facilitate future work. (5) Looking ahead, we identify several promising research directions worthy of further exploration and investment to continue advancing the field. The related resources and contents are updating in \url{https://github.com/QizhiPei/Awesome-Biomolecule-Language-Cross-Modeling}.

Masked Thought: Simply Masking Partial Reasoning Steps Can Improve Mathematical Reasoning Learning of Language Models

In reasoning tasks, even a minor error can cascade into inaccurate results, leading to suboptimal performance of large language models in such domains. Earlier fine-tuning approaches sought to mitigate this by leveraging more precise supervisory signals from human labeling, larger models, or self-sampling, although at a high cost. Conversely, we develop a method that avoids external resources, relying instead on introducing perturbations to the input. Our training approach randomly masks certain tokens within the chain of thought, a technique we found to be particularly effective for reasoning tasks. When applied to fine-tuning with GSM8K, this method achieved a 5% improvement in accuracy over standard supervised fine-tuning with a few codes modified and no additional labeling effort. Furthermore, it is complementary to existing methods. When integrated with related data augmentation methods, it leads to an average improvement of 3% improvement in GSM8K accuracy and 1% improvement in MATH accuracy across five datasets of various quality and size, as well as two base models. We further investigate the mechanisms behind this improvement through case studies and quantitative analysis, suggesting that our approach may provide superior support for the model in capturing long-distance dependencies, especially those related to questions. This enhancement could deepen understanding of premises in questions and prior steps. Our code is available at Github.

BioT5+: Towards Generalized Biological Understanding with IUPAC Integration and Multi-task Tuning

Recent research trends in computational biology have increasingly focused on integrating text and bio-entity modeling, especially in the context of molecules and proteins. However, previous efforts like BioT5 faced challenges in generalizing across diverse tasks and lacked a nuanced understanding of molecular structures, particularly in their textual representations (e.g., IUPAC). This paper introduces BioT5+, an extension of the BioT5 framework, tailored to enhance biological research and drug discovery. BioT5+ incorporates several novel features: integration of IUPAC names for molecular understanding, inclusion of extensive bio-text and molecule data from sources like bioRxiv and PubChem, the multi-task instruction tuning for generality across tasks, and a novel numerical tokenization technique for improved processing of numerical data. These enhancements allow BioT5+ to bridge the gap between molecular representations and their textual descriptions, providing a more holistic understanding of biological entities, and largely improving the grounded reasoning of bio-text and bio-sequences. The model is pre-trained and fine-tuned with a large number of experiments, including \emph{3 types of problems (classification, regression, generation), 15 kinds of tasks, and 21 total benchmark datasets}, demonstrating the remarkable performance and state-of-the-art results in most cases. BioT5+ stands out for its ability to capture intricate relationships in biological data, thereby contributing significantly to bioinformatics and computational biology. Our code is available at \url{https://github.com/QizhiPei/BioT5}.

Batch-ICL: Effective, Efficient, and Order-Agnostic In-Context Learning

In this paper, by treating in-context learning (ICL) as a meta-optimization process, we explain why LLMs are sensitive to the order of ICL examples. This understanding leads us to the development of Batch-ICL, an effective, efficient, and order-agnostic inference algorithm for ICL. Differing from the standard N-shot learning approach, Batch-ICL employs $N$ separate 1-shot forward computations and aggregates the resulting meta-gradients. These aggregated meta-gradients are then applied to a zero-shot learning to generate the final prediction. This batch processing approach renders the LLM agnostic to the order of ICL examples. Through extensive experiments and analysis, we demonstrate that Batch-ICL consistently outperforms most permutations of example sequences. In some cases, it even exceeds the performance of the optimal order for standard ICL, all while reducing the computational resources required. Furthermore, we develop a novel variant of Batch-ICL featuring multiple "epochs" of meta-optimization. This variant implicitly explores permutations of ICL examples, further enhancing ICL performance.

CharacterEval: A Chinese Benchmark for Role-Playing Conversational Agent Evaluation

Recently, the advent of large language models (LLMs) has revolutionized generative agents. Among them, Role-Playing Conversational Agents (RPCAs) attract considerable attention due to their ability to emotionally engage users. However, the absence of a comprehensive benchmark impedes progress in this field. To bridge this gap, we introduce CharacterEval, a Chinese benchmark for comprehensive RPCA assessment, complemented by a tailored high-quality dataset. The dataset comprises 1,785 multi-turn role-playing dialogues, encompassing 23,020 examples and featuring 77 characters derived from Chinese novels and scripts. It was carefully constructed, beginning with initial dialogue extraction via GPT-4, followed by rigorous human-led quality control, and enhanced with in-depth character profiles sourced from Baidu Baike. CharacterEval employs a multifaceted evaluation approach, encompassing thirteen targeted metrics on four dimensions. Comprehensive experiments on CharacterEval demonstrate that Chinese LLMs exhibit more promising capabilities than GPT-4 in Chinese role-playing conversation. Source code, data source and reward model will be publicly accessible at https://github.com/morecry/CharacterEval.

YAYI 2: Multilingual Open-Source Large Language Models

As the latest advancements in natural language processing, large language models (LLMs) have achieved human-level language understanding and generation abilities in many real-world tasks, and even have been regarded as a potential path to the artificial general intelligence. To better facilitate research on LLMs, many open-source LLMs, such as Llama 2 and Falcon, have recently been proposed and gained comparable performances to proprietary models. However, these models are primarily designed for English scenarios and exhibit poor performances in Chinese contexts. In this technical report, we propose YAYI 2, including both base and chat models, with 30 billion parameters. YAYI 2 is pre-trained from scratch on a multilingual corpus which contains 2.65 trillion tokens filtered by our pre-training data processing pipeline. The base model is aligned with human values through supervised fine-tuning with millions of instructions and reinforcement learning from human feedback. Extensive experiments on multiple benchmarks, such as MMLU and CMMLU, consistently demonstrate that the proposed YAYI 2 outperforms other similar sized open-source models.

Collaborative Synthesis of Patient Records through Multi-Visit Health State Inference

Electronic health records (EHRs) have become the foundation of machine learning applications in healthcare, while the utility of real patient records is often limited by privacy and security concerns. Synthetic EHR generation provides an additional perspective to compensate for this limitation. Most existing methods synthesize new records based on real EHR data, without consideration of different types of events in EHR data, which cannot control the event combinations in line with medical common sense. In this paper, we propose MSIC, a Multi-visit health Status Inference model for Collaborative EHR synthesis to address these limitations. First, we formulate the synthetic EHR generation process as a probabilistic graphical model and tightly connect different types of events by modeling the latent health states. Then, we derive a health state inference method tailored for the multi-visit scenario to effectively utilize previous records to synthesize current and future records. Furthermore, we propose to generate medical reports to add textual descriptions for each medical event, providing broader applications for synthesized EHR data. For generating different paragraphs in each visit, we incorporate a multi-generator deliberation framework to collaborate the message passing of multiple generators and employ a two-phase decoding strategy to generate high-quality reports. Our extensive experiments on the widely used benchmarks, MIMIC-III and MIMIC-IV, demonstrate that MSIC advances state-of-the-art results on the quality of synthetic data while maintaining low privacy risks.

Fortify the Shortest Stave in Attention: Enhancing Context Awareness of Large Language Models for Effective Tool Use

Recent advancements in large language models (LLMs) have significantly expanded their functionality and skills as tool agents. In this paper, we argue that a waveform pattern in the model's attention allocation has an impact on the tool use performance, which degrades when the position of essential information hits the trough zone. To address this issue, we propose a novel inference method named Attention Buckets. This approach enables LLMs to handle context by conducting parallel processes, each featuring a unique RoPE angle base that shapes the attention waveform. Attention Buckets ensures that an attention trough of a particular process can be compensated with an attention peak of another run, reducing the risk of the LLM missing essential information residing within the attention trough. Our extensive experiments on the widely recognized tool use benchmark demonstrate the efficacy of our approach, where a 7B-parameter open-source model enhanced by Attention Buckets achieves SOTA performance on par with GPT-4.