Callie
Abstract:Recent advances in vision-language models have enabled mobile GUI agents to perceive visual interfaces and execute user instructions, but reliable prediction of action consequences remains critical for long-horizon and high-risk interactions. Existing mobile world models provide either text-based or image-based future states, yet it remains unclear which representation is useful, whether generated rollouts can replace real environments, and how test-time guidance helps agents of different strengths. To answer the above questions, we filter and annotate mobile world-model data, then train world models across four modalities: delta text, full text, diffusion-based images, and renderable code. These models achieve SoTA performance on both MobileWorldBench and Code2WorldBench. Furthermore, by evaluating their downstream utility on AITZ, AndroidControl, and AndroidWorld, we obtain three findings. First, renderable code reconstruction achieves high in-distribution fidelity and provides effective multimodal supervision for data construction, while text-based feedback is more robust for online out-of-distribution (OOD) execution. Second, world-model-generated trajectories can provide transferable interaction experience in the training process and improve agents' end-to-end task performance, although these data do not preserve the original distribution. Last, for overconfident mobile agents with low action entropy, posterior self-reflection provides limited gains, suggesting that world models are more effective as prior perception or training supervision than as universal post-hoc verifiers.
Abstract:To unleash the full potential of AI for Science, we must untether the agents from a purely digital environment. The agent's ability to control and explore in real-world labs is essential because the physical lab remains foundational to scientific discovery. While some tasks can be performed on a computer (e.g., data analysis, running simulated experiments), Eureka moments could occur at any time while operating lab instruments (e.g., when a scientist notices unexpected clues, intuition may prompt a real-time course change). Although autonomous labs are on the rise, which expose programmable APIs to control scientific instruments via software, bridging the gap between increasingly powerful AI agents and automated lab equipment requires innovation that draws insights from computer systems. We propose a new paradigm called ``Experiment-as-Code (EaC) Labs,'' where a core concept is to encode experiments as declarative configurations that can be compiled down to device-level APIs. AI agents come up with hypotheses and experiments, written as an ensemble of declarative configurations. The systems layer performs program analysis, safety checks, resource assignment, and job orchestration. Finally, programmatic experimentation occurs via actuating the device APIs. This is a general stack that is science-, lab-, and instrument-independent, representing a novel synthesis across the physical, systems, and intelligence layers to unleash the next breakthrough in AI for Science.
Abstract:Explicit reconstruction constraints derived from the decoupled representation are further imposed to suppress abnormal channel amplification and chromatic noise. Experiments on LOLv2-Real, MIT-Adobe FiveK, and LSRW show that the proposed method achieves competitive or superior quantitative and visual performance, reaching 29.71 dB PSNR and 0.89 SSIM on LOLv2-Real. DarkFace experiments further indicate improved downstream face detection under low-light conditions. Code and pretrained models are available at: https://github.com/mubaisam/ICD.
Abstract:Predicting the outcomes of prospective clinical trials remains a major challenge for large language models. Prior work has shown that both traditional correlational predictors, such as random forests and logistic regression, and strong commercial LLMs achieve limited performance on this task. In this paper, we propose DeepImagine, a framework for teaching LLMs biomedical reasoning through successive counterfactual imagining. The central idea is to approximate hidden causal mechanisms of clinical trials by training models to infer how observed trial results would change under controlled perturbations of experimental conditions, such as dosage, outcome measures, study arms, geography, and other trial attributes. To support this objective, we construct both natural and approximate counterfactual pairs from real clinical trials with reported outcomes. For settings where strict counterfactual supervision is available, such as paired outcome measures or dose-ranging study arms within the same trial, we train models with supervised fine-tuning. For broader settings where only approximate counterfactual pairs can be retrieved, we optimize models with reinforcement learning using verifiable rewards based on downstream benchmark correctness. We further augment training with synthetic reasoning traces that provide causally plausible explanations for local counterfactual transitions. Using this pipeline, we train language models under 10B parameters, including Qwen3.5-9B, and evaluate them on clinical trial outcome prediction. We aim to show that DeepImagine consistently improves over untuned language models and traditional correlational baselines. Finally, we aim to show that the learned reasoning trajectories provide interpretable signals about how models represent trial-level mechanisms, suggesting a practical path toward more mechanistic and scientifically useful biomedical language models.
Abstract:Clinical deployment of automated brain MRI analysis faces a fundamental challenge: clinical data is heterogeneous and noisy, and high-quality labels are prohibitively costly to obtain. Self-supervised learning (SSL) can address this by leveraging the vast amounts of unlabeled data produced in clinical workflows to train robust \textit{foundation models} that adapt out-of-domain with minimal supervision. However, the development of foundation models for brain MRI has been limited by small pretraining datasets and in-domain benchmarking focused on high-quality, research-grade data. To address this gap, we organized the FOMO25 challenge as a satellite event at MICCAI 2025. FOMO25 provided participants with a large pretraining dataset, FOMO60K, and evaluated models on data sourced directly from clinical workflows in few-shot and out-of-domain settings. Tasks covered infarct classification, meningioma segmentation, and brain age regression, and considered both models trained on FOMO60K (method track) and any data (open track). Nineteen foundation models from sixteen teams were evaluated using a standardized containerized pipeline. Results show that (a) self-supervised pretraining improves generalization on clinical data under domain shift, with the strongest models trained \textit{out-of-domain} surpassing supervised baselines trained \textit{in-domain}. (b) No single pretraining objective benefits all tasks: MAE favors segmentation, hybrid reconstruction-contrastive objectives favor classification, and (c) strong performance was achieved by small pretrained models, and improvements from scaling model size and training duration did not yield reliable benefits.
Abstract:Text-video retrieval tasks have seen significant improvements due to the recent development of large-scale vision-language pre-trained models. Traditional methods primarily focus on video representations or cross-modal alignment, while recent works shift toward enriching text expressiveness to better match the rich semantics in videos. However, these methods use only interactions between text and frames/video, and ignore rich interactions among the internal frames within a video, so the final expanded text cannot capture frame contextual information, leading to disparities between text and video. In response, we introduce Energy-Aware Fine-Grained Relationship Learning Network (EagleNet) to generate accurate and context-aware enriched text embeddings. Specifically, the proposed Fine-Grained Relationship Learning mechanism (FRL) first constructs a text-frame graph by the generated text candidates and frames, then learns relationships among texts and frames, which are finally used to aggregate text candidates into an enriched text embedding that incorporates frame contextual information. To further improve fine-grained relationship learning in FRL, we design Energy-Aware Matching (EAM) to model the energy of text-frame interactions and thus accurately capture the distribution of real text-video pairs. Moreover, for more effective cross-modal alignment and stable training, we replace the conventional softmax-based contrastive loss with the sigmoid loss. Extensive experiments have demonstrated the superiority of EagleNet across MSRVTT, DiDeMo, MSVD, and VATEX. Codes are available at https://github.com/draym28/EagleNet.
Abstract:Low-light image enhancement aims to restore the visibility of images captured by visual sensors in dim environments by addressing their inherent signal degradations, such as luminance attenuation and structural corruption. Although numerous algorithms attempt to improve image quality, existing methods often cause a severe loss of intrinsic signal priors. To overcome these challenges, we propose a Dual-Stream Transformer Network (DST-Net) based on illumination-agnostic signal prior guidance and multi-scale spatial convolutions. First, to address the loss of critical signal features under low-light conditions, we design a feature extraction module. This module integrates Difference of Gaussians (DoG), LAB color space transformations, and VGG-16 for texture extraction, utilizing decoupled illumination-agnostic features as signal priors to continuously guide the enhancement process. Second, we construct a dual-stream interaction architecture. By employing a cross-modal attention mechanism, the network leverages the extracted priors to dynamically rectify the deteriorated signal representation of the enhanced image, ultimately achieving iterative enhancement through differentiable curve estimation. Furthermore, to overcome the inability of existing methods to preserve fine structures and textures, we propose a Multi-Scale Spatial Fusion Block (MSFB) featuring pseudo-3D and 3D gradient operator convolutions. This module integrates explicit gradient operators to recover high-frequency edges while capturing inter-channel spatial correlations via multi-scale spatial convolutions. Extensive evaluations and ablation studies demonstrate that DST-Net achieves superior performance in subjective visual quality and objective metrics. Specifically, our method achieves a PSNR of 25.64 dB on the LOL dataset. Subsequent validation on the LSRW dataset further confirms its robust cross-scene generalization.
Abstract:Skeleton-based action recognition is widely utilized in sensor systems including human-computer interaction and intelligent surveillance. Nevertheless, current sensor devices typically generate sparse skeleton data as discrete coordinates, which inevitably discards fine-grained spatiotemporal details during highly dynamic movements. Moreover, the rigid constraints of predefined physical sensor topologies hinder the modeling of latent long-range dependencies. To overcome these limitations, we propose KGS-GCN, a graph convolutional network that integrates kinematics-driven Gaussian splatting with probabilistic topology. Our framework explicitly addresses the challenges of sensor data sparsity and topological rigidity by transforming discrete joints into continuous generative representations. Firstly, a kinematics-driven Gaussian splatting module is designed to dynamically construct anisotropic covariance matrices using instantaneous joint velocity vectors. This module enhances visual representation by rendering sparse skeleton sequences into multi-view continuous heatmaps rich in spatiotemporal semantics. Secondly, to transcend the limitations of fixed physical connections, a probabilistic topology construction method is proposed. This approach generates an adaptive prior adjacency matrix by quantifying statistical correlations via the Bhattacharyya distance between joint Gaussian distributions. Ultimately, the GCN backbone is adaptively modulated by the rendered visual features via a visual context gating mechanism. Empirical results demonstrate that KGS-GCN significantly enhances the modeling of complex spatiotemporal dynamics. By addressing the inherent limitations of sparse inputs, our framework offers a robust solution for processing low-fidelity sensor data. This approach establishes a practical pathway for improving perceptual reliability in real-world sensing applications.
Abstract:Generative Engine Optimization (GEO) aims to improve content visibility in AI-generated responses. However, existing methods measure contribution-how much a document influences a response-rather than citation, the mechanism that actually drives traffic back to creators. Also, these methods apply generic rewriting rules uniformly, failing to diagnose why individual document are not cited. This paper introduces a diagnostic approach to GEO that asks why a document fails to be cited and intervenes accordingly. We develop a unified framework comprising: (1) the first taxonomy of citation failure modes spanning different stages of a citation pipeline; (2) AgentGEO, an agentic system that diagnoses failures using this taxonomy, selects targeted repairs from a corresponding tool library, and iterates until citation is achieved; and (3) a document-centric benchmark evaluating whether optimizations generalize across held-out queries. AgentGEO achieves over 40% relative improvement in citation rates while modifying only 5% of content, compared to 25% for baselines. Our analysis reveals that generic optimization can harm long-tail content and some documents face challenges that optimization alone cannot fully address-findings with implications for equitable visibility in AI-mediated information access.
Abstract:Significant progress has been made in low-light image enhancement with respect to visual quality. However, most existing methods primarily operate in the pixel domain or rely on implicit feature representations. As a result, the intrinsic geometric structural priors of images are often neglected. 2D Gaussian Splatting (2DGS) has emerged as a prominent explicit scene representation technique characterized by superior structural fitting capabilities and high rendering efficiency. Despite these advantages, the utilization of 2DGS in low-level vision tasks remains unexplored. To bridge this gap, LL-GaussianMap is proposed as the first unsupervised framework incorporating 2DGS into low-light image enhancement. Distinct from conventional methodologies, the enhancement task is formulated as a gain map generation process guided by 2DGS primitives. The proposed method comprises two primary stages. First, high-fidelity structural reconstruction is executed utilizing 2DGS. Then, data-driven enhancement dictionary coefficients are rendered via the rasterization mechanism of Gaussian splatting through an innovative unified enhancement module. This design effectively incorporates the structural perception capabilities of 2DGS into gain map generation, thereby preserving edges and suppressing artifacts during enhancement. Additionally, the reliance on paired data is circumvented through unsupervised learning. Experimental results demonstrate that LL-GaussianMap achieves superior enhancement performance with an extremely low storage footprint, highlighting the effectiveness of explicit Gaussian representations for image enhancement.