Lymphocyte Mimicry Correction via Region-Level Tissue Reasoning and Unbalanced Optimal Transport

Cell mimicry arises when different cell types appear morphologically similar. Human pathologists resolve this ambiguity using surrounding tissue context, whereas current vision models either lack contextual reasoning (cell foundation models) or cannot operate at the cell level (pathology MLLMs). We present Loki-OT, which propagates region-level tissue reasoning to individual cell predictions via Unbalanced Optimal Transport, using MLLM-derived density priors as soft guidance for ambiguous cell reassignment. Loki-OT is motivated by the observation that pretrained cell foundation model features already encode discriminative information, including tissue context, but standard cell-level supervision fails to use tissue context effectively. The resulting transport plan is distilled into a lightweight student MLP classifier that learns context-aware decision boundaries within the pretrained feature space. On the independent TCGA-BRCA cohort, Loki-OT achieved lower patient-level MAE than the fully supervised in-domain PanopTILs classifier and improved F1 in epithelium-rich mimicry tissues, using 278 weak region-level MLLM estimates built on a general-domain cell foundation model. Code: https://github.com/xiangli980/Lymphocyte_Mimicry_Correction_via_Loki_OT

Auditable agentic AI for evidence-grounded thyroid ultrasound diagnosis and reporting

Thyroid ultrasound diagnosis requires coordinated lesion localization, measurement, risk stratification and reporting, yet most AI systems address these tasks in isolation and provide limited support for clinical review. We present ThyroidXAgent, a clinician-interactive agentic AI system that coordinates specialized diagnostic tools and stores their outputs as an auditable case-level evidence record. The system was developed using OpenThyroidDB, a multicentre, multitask resource integrating approximately 0.3 million ultrasound images and 24,000 paired reports, and was evaluated on 28,458 non-overlapping test cases, including 8,721 cases from 35 centres in the private NHC-MISD-TUS cohort. Across heterogeneous datasets, ThyroidXAgent achieved a mean Dice score of 87.21 percent for nodule segmentation and a mean AUROC of 0.9466 for benign-malignant classification. The same workflow supported lymph-node metastasis prediction and follicular versus papillary thyroid carcinoma classification, with AUROCs of 0.864 and 0.805, respectively. For report generation, evidence-grounded assembly outperformed multimodal language-model baselines across three cohorts. ThyClinScore, a lesion-level clinical semantic metric introduced here, showed the strongest correlation with a location-aware language-model judge. ThyroidXAgent improved physician classification accuracy, increased report diagnostic consistency from 70.3 percent to 86.2 percent, and reduced segmentation and reporting time by 35.9 percent and 27.4 percent, respectively. These findings support auditable, clinician-correctable agentic AI for thyroid ultrasound diagnosis and reporting.

PhiZero: A World Model Built Around Physical Language

We introduce PhiZero, a physical world model built around physical language, a compact discrete representation of world-state transitions. Existing physical world models typically predict future videos directly in pixel space, leaving the underlying world dynamics implicit within high-dimensional visual predictors. Motivated by humans' ability to abstract predictive structure from visual experience and organize it in natural language for explicit reasoning, we learn physical language from in-the-wild videos through self-supervision and use it to explicitly reason about how the physical world evolves. Accordingly, PhiZero adopts a reason-then-render paradigm: it first infers future world evolution as a physical-language sequence and then renders the inferred transitions into videos. Extensive experiments across generation and understanding benchmarks validate the ability of PhiZero to model physically coherent world evolution. We further show its potential for realistic and interactive world modeling, fine-grained action-conditioned simulation, and zero-shot motion transfer.

XALPHA: A Memory-Driven AI Quant Researcher for Hypothesis-to-Code Alpha Discovery

Financial markets are noisy, non-stationary, and high-dimensional, making it difficult to discover predictive and robust trading signals. Alpha discovery has evolved from manual factor design to machine learning, evolutionary search, and recent LLM-based frameworks, improving the efficiency of factor generation, search, and evaluation. However, existing methods still mostly automate isolated steps, rather than functioning as end-to-end quant researchers that can absorb external knowledge, close the hypothesis-to-code validation loop, and learn from accumulated discovery feedback. To fill this gap, we introduce XAlpha, a memory-driven AI Quant Researcher for continuous hypothesis-to-code alpha discovery. XAlpha maintains a multi-source research memory system that integrates report-grounded financial knowledge with discovery feedback from prior generations and research cycles. Guided by this memory system, a Macro Brain plans research themes and selects suitable Archetypes; a Micro Brain transforms the planned hypothesis pool into executable factor code and verifies ex-ante tri-alignment among the hypothesis idea, code logic, and financial plausibility; and a Cross Brain consolidates empirical outcomes into generation-level feedback, cycle-level summaries, and archetype-level research cues for future exploration. In this way, XAlpha turns alpha mining from isolated factor generation into a closed-loop research process that continuously reads, hypothesizes, implements, validates, reflects, and evolves. Experiments on CSI300 show that XAlpha achieves stronger overall alpha discovery performance than representative baselines.

Bridging Video Understanding and Generation in a Unified Framework

Recently, unified image generation and understanding have been extensively explored. However, extending such unified modeling paradigms to the video domain remains largely underexplored. A central challenge is that video understanding favors compact, discriminative semantic representations, whereas video generation requires dense signals that preserve visual details and temporal coherence. Videos naturally capture both spatial semantics and temporal dynamics, making them a more suitable modality for unified multimodal modeling compared to static images. In this paper, we propose Vega, a unified framework that bridges video understanding and generation. Vega leverages a shared vocabulary to jointly model text and visual representations and employs a hybrid architecture combining autoregressive (AR) prediction with diffusion-based rendering. Specifically, the AR model focuses on predicting semantically meaningful visual tokens for keyframes, providing a structured representation that guides the diffusion module in rendering dense, high-resolution video frames. Extensive experiments demonstrate that Vega achieves strong performance on video generation benchmarks such as VBench and video understanding benchmarks like VideoMME.

HumanScale: Egocentric Human Video Can Outperform Real-Robot Data for Embodied Pretraining

Embodied foundation models are expected to benefit from data scaling like large language models, but face a much tighter data bottleneck. Teleoperated real-robot trajectories remain the dominant pretraining source due to their precise action supervision and embodiment alignment, yet their scalability is limited by high collection cost, acquisition difficulty, and low behavioral and environmental diversity. These limitations have sparked interest in egocentric human video as a scalable, substantially lower-cost, and more diverse alternative for embodied model pretraining. However, its effectiveness compared to teleoperated real-robot data remains underexplored. To address this question, we conduct a systematic study comparing egocentric human video and teleoperated real-robot trajectories as pretraining data sources for embodied foundation models, under fixed post-training and validation protocols. Surprisingly, we find that egocentric data, when processed through a carefully designed filtering and labeling pipeline, is not merely a viable substitute for model pretraining but can lead to superior performance. With the same amount of pretraining data, models pretrained on egocentric data achieve a 24% lower validation loss on real-robot action prediction, as well as 52.5% and 90% higher success rates on in-distribution and out-of-distribution real-robot task execution, respectively. This finding verifies a scalable paradigm for embodied foundation models: pretrain on egocentric human video to learn diverse world representations, then adapt with a small amount of labeled real-robot data for action-space alignment. We hope this study encourages broader exploration of egocentric data and offers guidance for data quality assessment before costly robot data collection.

Semantic Triplet Restoration: A Novel Protocol for Hierarchical Table Understanding in Large Language Models

Table question answering requires models to recover semantic relations encoded implicitly by two-dimensional layout, merged cells, and hierarchical headers. Current pipelines typically use HTML or Markdown as intermediate table representations, but these layout-oriented serializations introduce markup overhead and require large language models to infer header-cell alignments from row and column spans. We propose Semantic Triplet Restoration (STR), a protocol that rewrites each cell as an atomic fact <item path, feature path, value>, where the item path specifies the row-wise entity, the feature path specifies the hierarchical attribute, and the value contains the cell content. We also present TripletQL, a lightweight query-aware router that uses STR to select an appropriate rendering or filtered subset of triplets for each question. Across four Chinese and English table-QA benchmarks, STR matches or improves upon HTML-based baselines while reducing input tokens. The relative benefit grows for smaller language models and longer table contexts, suggesting that explicit semantic representations are especially useful under constrained inference budgets. Code and data are available at https://github.com/Phoenix-ni/STR.git .

Surg-R1: A Hierarchical Reasoning Foundation Model for Scalable and Interpretable Surgical Decision Support with Multi-Center Clinical Validation

Surgical scene understanding demands not only accurate predictions but also interpretable reasoning that surgeons can verify against clinical expertise. However, existing surgical vision-language models generate predictions without reasoning chains, and general-purpose reasoning models fail on compositional surgical tasks without domain-specific knowledge. We present Surg-R1, a surgical Vision-Language Model that addresses this gap through hierarchical reasoning trained via a four-stage pipeline. Our approach introduces three key contributions: (1) a three-level reasoning hierarchy decomposing surgical interpretation into perceptual grounding, relational understanding, and contextual reasoning; (2) the largest surgical chain-of-thought dataset with 320,000 reasoning pairs; and (3) a four-stage training pipeline progressing from supervised fine-tuning to group relative policy optimization and iterative self-improvement. Evaluation on SurgBench, comprising six public benchmarks and six multi-center external validation datasets from five institutions, demonstrates that Surg-R1 achieves the highest Arena Score (64.9%) on public benchmarks versus Gemini 3.0 Pro (46.1%) and GPT-5.1 (37.9%), outperforming both proprietary reasoning models and specialized surgical VLMs on the majority of tasks spanning instrument localization, triplet recognition, phase recognition, action recognition, and critical view of safety assessment, with a 15.2 percentage point improvement over the strongest surgical baseline on external validation.

DynVLA: Learning World Dynamics for Action Reasoning in Autonomous Driving

We propose DynVLA, a driving VLA model that introduces a new CoT paradigm termed Dynamics CoT. DynVLA forecasts compact world dynamics before action generation, enabling more informed and physically grounded decision-making. To obtain compact dynamics representations, DynVLA introduces a Dynamics Tokenizer that compresses future evolution into a small set of dynamics tokens. Considering the rich environment dynamics in interaction-intensive driving scenarios, DynVLA decouples ego-centric and environment-centric dynamics, yielding more accurate world dynamics modeling. We then train DynVLA to generate dynamics tokens before actions through SFT and RFT, improving decision quality while maintaining latency-efficient inference. Compared to Textual CoT, which lacks fine-grained spatiotemporal understanding, and Visual CoT, which introduces substantial redundancy due to dense image prediction, Dynamics CoT captures the evolution of the world in a compact, interpretable, and efficient form. Extensive experiments on NAVSIM, Bench2Drive, and a large-scale in-house dataset demonstrate that DynVLA consistently outperforms Textual CoT and Visual CoT methods, validating the effectiveness and practical value of Dynamics CoT.

Scaling World Model for Hierarchical Manipulation Policies

Vision-Language-Action (VLA) models are promising for generalist robot manipulation but remain brittle in out-of-distribution (OOD) settings, especially with limited real-robot data. To resolve the generalization bottleneck, we introduce a hierarchical Vision-Language-Action framework \our{} that leverages the generalization of large-scale pre-trained world model for robust and generalizable VIsual Subgoal TAsk decomposition VISTA. Our hierarchical framework \our{} consists of a world model as the high-level planner and a VLA as the low-level executor. The high-level world model first divides manipulation tasks into subtask sequences with goal images, and the low-level policy follows the textual and visual guidance to generate action sequences. Compared to raw textual goal specification, these synthesized goal images provide visually and physically grounded details for low-level policies, making it feasible to generalize across unseen objects and novel scenarios. We validate both visual goal synthesis and our hierarchical VLA policies in massive out-of-distribution scenarios, and the performance of the same-structured VLA in novel scenarios could boost from 14% to 69% with the guidance generated by the world model. Results demonstrate that our method outperforms previous baselines with a clear margin, particularly in out-of-distribution scenarios. Project page: \href{https://vista-wm.github.io/}{https://vista-wm.github.io}