Controllable Singing Style Conversion with Boundary-Aware Information Bottleneck

This paper presents the submission of the S4 team to the Singing Voice Conversion Challenge 2025 (SVCC2025)-a novel singing style conversion system that advances fine-grained style conversion and control within in-domain settings. To address the critical challenges of style leakage, dynamic rendering, and high-fidelity generation with limited data, we introduce three key innovations: a boundary-aware Whisper bottleneck that pools phoneme-span representations to suppress residual source style while preserving linguistic content; an explicit frame-level technique matrix, enhanced by targeted F0 processing during inference, for stable and distinct dynamic style rendering; and a perceptually motivated high-frequency band completion strategy that leverages an auxiliary standard 48kHz SVC model to augment the high-frequency spectrum, thereby overcoming data scarcity without overfitting. In the official SVCC2025 subjective evaluation, our system achieves the best naturalness performance among all submissions while maintaining competitive results in speaker similarity and technique control, despite using significantly less extra singing data than other top-performing systems. Audio samples are available online.

DINO-VO: Learning Where to Focus for Enhanced State Estimation

We present DINO Patch Visual Odometry (DINO-VO), an end-to-end monocular visual odometry system with strong scene generalization. Current Visual Odometry (VO) systems often rely on heuristic feature extraction strategies, which can degrade accuracy and robustness, particularly in large-scale outdoor environments. DINO-VO addresses these limitations by incorporating a differentiable adaptive patch selector into the end-to-end pipeline, improving the quality of extracted patches and enhancing generalization across diverse datasets. Additionally, our system integrates a multi-task feature extraction module with a differentiable bundle adjustment (BA) module that leverages inverse depth priors, enabling the system to learn and utilize appearance and geometric information effectively. This integration bridges the gap between feature learning and state estimation. Extensive experiments on the TartanAir, KITTI, Euroc, and TUM datasets demonstrate that DINO-VO exhibits strong generalization across synthetic, indoor, and outdoor environments, achieving state-of-the-art tracking accuracy.

Perturb-and-Restore: Simulation-driven Structural Augmentation Framework for Imbalance Chromosomal Anomaly Detection

Detecting structural chromosomal abnormalities is crucial for accurate diagnosis and management of genetic disorders. However, collecting sufficient structural abnormality data is extremely challenging and costly in clinical practice, and not all abnormal types can be readily collected. As a result, deep learning approaches face significant performance degradation due to the severe imbalance and scarcity of abnormal chromosome data. To address this challenge, we propose a Perturb-and-Restore (P&R), a simulation-driven structural augmentation framework that effectively alleviates data imbalance in chromosome anomaly detection. The P&R framework comprises two key components: (1) Structure Perturbation and Restoration Simulation, which generates synthetic abnormal chromosomes by perturbing chromosomal banding patterns of normal chromosomes followed by a restoration diffusion network that reconstructs continuous chromosome content and edges, thus eliminating reliance on rare abnormal samples; and (2) Energy-guided Adaptive Sampling, an energy score-based online selection strategy that dynamically prioritizes high-quality synthetic samples by referencing the energy distribution of real samples. To evaluate our method, we construct a comprehensive structural anomaly dataset consisting of over 260,000 chromosome images, including 4,242 abnormal samples spanning 24 categories. Experimental results demonstrate that the P&R framework achieves state-of-the-art (SOTA) performance, surpassing existing methods with an average improvement of 8.92% in sensitivity, 8.89% in precision, and 13.79% in F1-score across all categories.

MacTok: Robust Continuous Tokenization for Image Generation

Continuous image tokenizers enable efficient visual generation, and those based on variational frameworks can learn smooth, structured latent representations through KL regularization. Yet this often leads to posterior collapse when using fewer tokens, where the encoder fails to encode informative features into the compressed latent space. To address this, we introduce \textbf{MacTok}, a \textbf{M}asked \textbf{A}ugmenting 1D \textbf{C}ontinuous \textbf{Tok}enizer that leverages image masking and representation alignment to prevent collapse while learning compact and robust representations. MacTok applies both random masking to regularize latent learning and DINO-guided semantic masking to emphasize informative regions in images, forcing the model to encode robust semantics from incomplete visual evidence. Combined with global and local representation alignment, MacTok preserves rich discriminative information in a highly compressed 1D latent space, requiring only 64 or 128 tokens. On ImageNet, MacTok achieves a competitive gFID of 1.44 at 256$\times$256 and a state-of-the-art 1.52 at 512$\times$512 with SiT-XL, while reducing token usage by up to 64$\times$. These results confirm that masking and semantic guidance together prevent posterior collapse and achieve efficient, high-fidelity tokenization.

GIFT: Global Irreplaceability Frame Targeting for Efficient Video Understanding

Video Large Language Models (VLMs) have achieved remarkable success in video understanding, but the significant computational cost from processing dense frames severely limits their practical application. Existing methods alleviate this by selecting keyframes, but their greedy decision-making, combined with a decoupled evaluation of relevance and diversity, often falls into local optima and results in erroneously selecting irrelevant noise frames. To address these challenges, we propose GIFT: Global Irreplaceability Frame Targeting, a novel training-free framework that selects frames by assessing their intrinsic irreplaceability. Specifically, we first introduce Directed Diversity to quantify a frame's uniqueness conditioned on relevance, which allows us to formulate a unified irreplaceability score. Subsequently, our Budget-Aware Refinement strategy employs a adaptive iterative process that first secures a core set of frames with the highest irreplaceability, and then shifts its priority to building crucial temporal context around these selections as the budget expands. Extensive experiments demonstrate that GIFT achieves a maximum average improvement of 12.5% across long-form video benchmarks on LLaVA-Video-7B compared to uniform sampling.

Colon-Bench: An Agentic Workflow for Scalable Dense Lesion Annotation in Full-Procedure Colonoscopy Videos

Early screening via colonoscopy is critical for colon cancer prevention, yet developing robust AI systems for this domain is hindered by the lack of densely annotated, long-sequence video datasets. Existing datasets predominantly focus on single-class polyp detection and lack the rich spatial, temporal, and linguistic annotations required to evaluate modern Multimodal Large Language Models (MLLMs). To address this critical gap, we introduce Colon-Bench, generated via a novel multi-stage agentic workflow. Our pipeline seamlessly integrates temporal proposals, bounding-box tracking, AI-driven visual confirmation, and human-in-the-loop review to scalably annotate full-procedure videos. The resulting verified benchmark is unprecedented in scope, encompassing 528 videos, 14 distinct lesion categories (including polyps, ulcers, and bleeding), over 300,000 bounding boxes, 213,000 segmentation masks, and 133,000 words of clinical descriptions. We utilize Colon-Bench to rigorously evaluate state-of-the-art MLLMs across lesion classification, Open-Vocabulary Video Object Segmentation (OV-VOS), and video Visual Question Answering (VQA). The MLLM results demonstrate surprisingly high localization performance in medical domains compared to SAM-3. Finally, we analyze common VQA errors from MLLMs to introduce a novel "colon-skill" prompting strategy, improving zero-shot MLLM performance by up to 9.7% across most MLLMs. The dataset and the code are available at https://abdullahamdi.com/colon-bench .

BizGenEval: A Systematic Benchmark for Commercial Visual Content Generation

Recent advances in image generation models have expanded their applications beyond aesthetic imagery toward practical visual content creation. However, existing benchmarks mainly focus on natural image synthesis and fail to systematically evaluate models under the structured and multi-constraint requirements of real-world commercial design tasks. In this work, we introduce BizGenEval, a systematic benchmark for commercial visual content generation. The benchmark spans five representative document types: slides, charts, webpages, posters, and scientific figures, and evaluates four key capability dimensions: text rendering, layout control, attribute binding, and knowledge-based reasoning, forming 20 diverse evaluation tasks. BizGenEval contains 400 carefully curated prompts and 8000 human-verified checklist questions to rigorously assess whether generated images satisfy complex visual and semantic constraints. We conduct large-scale benchmarking on 26 popular image generation systems, including state-of-the-art commercial APIs and leading open-source models. The results reveal substantial capability gaps between current generative models and the requirements of professional visual content creation. We hope BizGenEval serves as a standardized benchmark for real-world commercial visual content generation.

Developing Foundation Models for Universal Segmentation from 3D Whole-Body Positron Emission Tomography

Positron emission tomography (PET) is a key nuclear medicine imaging modality that visualizes radiotracer distributions to quantify in vivo physiological and metabolic processes, playing an irreplaceable role in disease management. Despite its clinical importance, the development of deep learning models for quantitative PET image analysis remains severely limited, driven by both the inherent segmentation challenge from PET's paucity of anatomical contrast and the high costs of data acquisition and annotation. To bridge this gap, we develop generalist foundational models for universal segmentation from 3D whole-body PET imaging. We first build the largest and most comprehensive PET dataset to date, comprising 11041 3D whole-body PET scans with 59831 segmentation masks for model development. Based on this dataset, we present SegAnyPET, an innovative foundational model with general-purpose applicability to diverse segmentation tasks. Built on a 3D architecture with a prompt engineering strategy for mask generation, SegAnyPET enables universal and scalable organ and lesion segmentation, supports efficient human correction with minimal effort, and enables a clinical human-in-the-loop workflow. Extensive evaluations on multi-center, multi-tracer, multi-disease datasets demonstrate that SegAnyPET achieves strong zero-shot performance across a wide range of segmentation tasks, highlighting its potential to advance the clinical applications of molecular imaging.

Higher-Order Modular Attention: Fusing Pairwise and Triadic Interactions for Protein Sequences

Transformer self-attention computes pairwise token interactions, yet protein sequence to phenotype relationships often involve cooperative dependencies among three or more residues that dot product attention does not capture explicitly. We introduce Higher-Order Modular Attention, HOMA, a unified attention operator that fuses pairwise attention with an explicit triadic interaction pathway. To make triadic attention practical on long sequences, HOMA employs block-structured, windowed triadic attention. We evaluate on three TAPE benchmarks for Secondary Structure, Fluorescence, and Stability. Our attention mechanism yields consistent improvements across all tasks compared with standard self-attention and efficient variants including block-wise attention and Linformer. These results suggest that explicit triadic terms provide complementary representational capacity for protein sequence prediction at controllable additional computational cost.

HiFi-Inpaint: Towards High-Fidelity Reference-Based Inpainting for Generating Detail-Preserving Human-Product Images

Human-product images, which showcase the integration of humans and products, play a vital role in advertising, e-commerce, and digital marketing. The essential challenge of generating such images lies in ensuring the high-fidelity preservation of product details. Among existing paradigms, reference-based inpainting offers a targeted solution by leveraging product reference images to guide the inpainting process. However, limitations remain in three key aspects: the lack of diverse large-scale training data, the struggle of current models to focus on product detail preservation, and the inability of coarse supervision for achieving precise guidance. To address these issues, we propose HiFi-Inpaint, a novel high-fidelity reference-based inpainting framework tailored for generating human-product images. HiFi-Inpaint introduces Shared Enhancement Attention (SEA) to refine fine-grained product features and Detail-Aware Loss (DAL) to enforce precise pixel-level supervision using high-frequency maps. Additionally, we construct a new dataset, HP-Image-40K, with samples curated from self-synthesis data and processed with automatic filtering. Experimental results show that HiFi-Inpaint achieves state-of-the-art performance, delivering detail-preserving human-product images.