Atomic Trajectory Modeling with State Space Models for Biomolecular Dynamics

Understanding the dynamic behavior of biomolecules is fundamental to elucidating biological function and facilitating drug discovery. While Molecular Dynamics (MD) simulations provide a rigorous physical basis for studying these dynamics, they remain computationally expensive for long timescales. Conversely, recent deep generative models accelerate conformation generation but are typically either failing to model temporal relationship or built only for monomeric proteins. To bridge this gap, we introduce ATMOS, a novel generative framework based on State Space Models (SSM) designed to generate atom-level MD trajectories for biomolecular systems. ATMOS integrates a Pairformer-based state transition mechanism to capture long-range temporal dependencies, with a diffusion-based module to decode trajectory frames in an autoregressive manner. ATMOS is trained across crystal structures from PDB and conformation trajectory from large-scale MD simulation datasets including mdCATH and MISATO. We demonstrate that ATMOS achieves state-of-the-art performance in generating conformation trajectories for both protein monomers and complex protein-ligand systems. By enabling efficient inference of atomic trajectory of motions, this work establishes a promising foundation for modeling biomolecular dynamics.

Load-Aware Locomotion Control for Humanoid Robots in Industrial Transportation Tasks

Humanoid robots deployed in industrial environments are required to perform load-carrying transportation tasks that tightly couple locomotion and manipulation. However, achieving stable and robust locomotion under varying payloads and upper-body motions is challenging due to dynamic coupling and partial observability. This paper presents a load-aware locomotion framework for industrial humanoids based on a decoupled yet coordinated loco-manipulation architecture. Lower-body locomotion is controlled via a reinforcement learning policy producing residual joint actions on kinematically derived nominal configurations. A kinematics-based locomotion reference with a height-conditioned joint-space offset guides learning, while a history-based state estimator infers base linear velocity and height and encodes residual load- and manipulation-induced disturbances in a compact latent representation. The framework is trained entirely in simulation and deployed on a full-size humanoid robot without fine-tuning. Simulation and real-world experiments demonstrate faster training, accurate height tracking, and stable loco-manipulation. Project page: https://lequn-f.github.io/LALO/

Uni-ASR: Unified LLM-Based Architecture for Non-Streaming and Streaming Automatic Speech Recognition

Although the deep integration of the Automatic Speech Recognition (ASR) system with Large Language Models (LLMs) has significantly improved accuracy, the deployment of such systems in low-latency streaming scenarios remains challenging. In this paper, we propose Uni-ASR, a unified framework based on LLMs that integrates both non-streaming and streaming speech recognition capabilities. We propose a joint training paradigm that enables the system to seamlessly transition between two recognition modes without any architectural modifications. Furthermore, we introduce a context-aware training paradigm and a co-designed fallback decoding strategy, which can enhance streaming recognition accuracy without introducing additional latency. The experimental results demonstrate that Uni-ASR not only achieves competitive performance within non-streaming mode, but also demonstrates strong effectiveness in streaming scenarios under diverse latency constraints.

PerturbDiff: Functional Diffusion for Single-Cell Perturbation Modeling

Building Virtual Cells that can accurately simulate cellular responses to perturbations is a long-standing goal in systems biology. A fundamental challenge is that high-throughput single-cell sequencing is destructive: the same cell cannot be observed both before and after a perturbation. Thus, perturbation prediction requires mapping unpaired control and perturbed populations. Existing models address this by learning maps between distributions, but typically assume a single fixed response distribution when conditioned on observed cellular context (e.g., cell type) and the perturbation type. In reality, responses vary systematically due to unobservable latent factors such as microenvironmental fluctuations and complex batch effects, forming a manifold of possible distributions for the same observed conditions. To account for this variability, we introduce PerturbDiff, which shifts modeling from individual cells to entire distributions. By embedding distributions as points in a Hilbert space, we define a diffusion-based generative process operating directly over probability distributions. This allows PerturbDiff to capture population-level response shifts across hidden factors. Benchmarks on established datasets show that PerturbDiff achieves state-of-the-art performance in single-cell response prediction and generalizes substantially better to unseen perturbations. See our project page (https://katarinayuan.github.io/PerturbDiff-ProjectPage/), where code and data will be made publicly available (https://github.com/DeepGraphLearning/PerturbDiff).

RoboGene: Boosting VLA Pre-training via Diversity-Driven Agentic Framework for Real-World Task Generation

The pursuit of general-purpose robotic manipulation is hindered by the scarcity of diverse, real-world interaction data. Unlike data collection from web in vision or language, robotic data collection is an active process incurring prohibitive physical costs. Consequently, automated task curation to maximize data value remains a critical yet under-explored challenge. Existing manual methods are unscalable and biased toward common tasks, while off-the-shelf foundation models often hallucinate physically infeasible instructions. To address this, we introduce RoboGene, an agentic framework designed to automate the generation of diverse, physically plausible manipulation tasks across single-arm, dual-arm, and mobile robots. RoboGene integrates three core components: diversity-driven sampling for broad task coverage, self-reflection mechanisms to enforce physical constraints, and human-in-the-loop refinement for continuous improvement. We conduct extensive quantitative analysis and large-scale real-world experiments, collecting datasets of 18k trajectories and introducing novel metrics to assess task quality, feasibility, and diversity. Results demonstrate that RoboGene significantly outperforms state-of-the-art foundation models (e.g., GPT-4o, Gemini 2.5 Pro). Furthermore, real-world experiments show that VLA models pre-trained with RoboGene achieve higher success rates and superior generalization, underscoring the importance of high-quality task generation. Our project is available at https://robogene-boost-vla.github.io.

MeshMimic: Geometry-Aware Humanoid Motion Learning through 3D Scene Reconstruction

Humanoid motion control has witnessed significant breakthroughs in recent years, with deep reinforcement learning (RL) emerging as a primary catalyst for achieving complex, human-like behaviors. However, the high dimensionality and intricate dynamics of humanoid robots make manual motion design impractical, leading to a heavy reliance on expensive motion capture (MoCap) data. These datasets are not only costly to acquire but also frequently lack the necessary geometric context of the surrounding physical environment. Consequently, existing motion synthesis frameworks often suffer from a decoupling of motion and scene, resulting in physical inconsistencies such as contact slippage or mesh penetration during terrain-aware tasks. In this work, we present MeshMimic, an innovative framework that bridges 3D scene reconstruction and embodied intelligence to enable humanoid robots to learn coupled "motion-terrain" interactions directly from video. By leveraging state-of-the-art 3D vision models, our framework precisely segments and reconstructs both human trajectories and the underlying 3D geometry of terrains and objects. We introduce an optimization algorithm based on kinematic consistency to extract high-quality motion data from noisy visual reconstructions, alongside a contact-invariant retargeting method that transfers human-environment interaction features to the humanoid agent. Experimental results demonstrate that MeshMimic achieves robust, highly dynamic performance across diverse and challenging terrains. Our approach proves that a low-cost pipeline utilizing only consumer-grade monocular sensors can facilitate the training of complex physical interactions, offering a scalable path toward the autonomous evolution of humanoid robots in unstructured environments.

RoboAug: One Annotation to Hundreds of Scenes via Region-Contrastive Data Augmentation for Robotic Manipulation

Enhancing the generalization capability of robotic learning to enable robots to operate effectively in diverse, unseen scenes is a fundamental and challenging problem. Existing approaches often depend on pretraining with large-scale data collection, which is labor-intensive and time-consuming, or on semantic data augmentation techniques that necessitate an impractical assumption of flawless upstream object detection in real-world scenarios. In this work, we propose RoboAug, a novel generative data augmentation framework that significantly minimizes the reliance on large-scale pretraining and the perfect visual recognition assumption by requiring only the bounding box annotation of a single image during training. Leveraging this minimal information, RoboAug employs pre-trained generative models for precise semantic data augmentation and integrates a plug-and-play region-contrastive loss to help models focus on task-relevant regions, thereby improving generalization and boosting task success rates. We conduct extensive real-world experiments on three robots, namely UR-5e, AgileX, and Tien Kung 2.0, spanning over 35k rollouts. Empirical results demonstrate that RoboAug significantly outperforms state-of-the-art data augmentation baselines. Specifically, when evaluating generalization capabilities in unseen scenes featuring diverse combinations of backgrounds, distractors, and lighting conditions, our method achieves substantial gains over the baseline without augmentation. The success rates increase from 0.09 to 0.47 on UR-5e, from 0.16 to 0.60 on AgileX, and from 0.19 to 0.67 on Tien Kung 2.0. These results highlight the superior generalization and effectiveness of RoboAug in real-world manipulation tasks. Our project is available at https://x-roboaug.github.io/.

CRAFT: Adapting VLA Models to Contact-rich Manipulation via Force-aware Curriculum Fine-tuning

Vision-Language-Action (VLA) models have shown a strong capability in enabling robots to execute general instructions, yet they struggle with contact-rich manipulation tasks, where success requires precise alignment, stable contact maintenance, and effective handling of deformable objects. A fundamental challenge arises from the imbalance between high-entropy vision and language inputs and low-entropy but critical force signals, which often leads to over-reliance on perception and unstable control. To address this, we introduce CRAFT, a force-aware curriculum fine-tuning framework that integrates a variational information bottleneck module to regulate vision and language embeddings during early training. This curriculum strategy encourages the model to prioritize force signals initially, before progressively restoring access to the full multimodal information. To enable force-aware learning, we further design a homologous leader-follower teleoperation system that collects synchronized vision, language, and force data across diverse contact-rich tasks. Real-world experiments demonstrate that CRAFT consistently improves task success, generalizes to unseen objects and novel task variations, and adapts effectively across diverse VLA architectures, enabling robust and generalizable contact-rich manipulation.

TC-IDM: Grounding Video Generation for Executable Zero-shot Robot Motion

The vision-language-action (VLA) paradigm has enabled powerful robotic control by leveraging vision-language models, but its reliance on large-scale, high-quality robot data limits its generalization. Generative world models offer a promising alternative for general-purpose embodied AI, yet a critical gap remains between their pixel-level plans and physically executable actions. To this end, we propose the Tool-Centric Inverse Dynamics Model (TC-IDM). By focusing on the tool's imagined trajectory as synthesized by the world model, TC-IDM establishes a robust intermediate representation that bridges the gap between visual planning and physical control. TC-IDM extracts the tool's point cloud trajectories via segmentation and 3D motion estimation from generated videos. Considering diverse tool attributes, our architecture employs decoupled action heads to project these planned trajectories into 6-DoF end-effector motions and corresponding control signals. This plan-and-translate paradigm not only supports a wide range of end-effectors but also significantly improves viewpoint invariance. Furthermore, it exhibits strong generalization capabilities across long-horizon and out-of-distribution tasks, including interacting with deformable objects. In real-world evaluations, the world model with TC-IDM achieves an average success rate of 61.11 percent, with 77.7 percent on simple tasks and 38.46 percent on zero-shot deformable object tasks. It substantially outperforms end-to-end VLA-style baselines and other inverse dynamics models.

Wow, wo, val! A Comprehensive Embodied World Model Evaluation Turing Test

As world models gain momentum in Embodied AI, an increasing number of works explore using video foundation models as predictive world models for downstream embodied tasks like 3D prediction or interactive generation. However, before exploring these downstream tasks, video foundation models still have two critical questions unanswered: (1) whether their generative generalization is sufficient to maintain perceptual fidelity in the eyes of human observers, and (2) whether they are robust enough to serve as a universal prior for real-world embodied agents. To provide a standardized framework for answering these questions, we introduce the Embodied Turing Test benchmark: WoW-World-Eval (Wow,wo,val). Building upon 609 robot manipulation data, Wow-wo-val examines five core abilities, including perception, planning, prediction, generalization, and execution. We propose a comprehensive evaluation protocol with 22 metrics to assess the models' generation ability, which achieves a high Pearson Correlation between the overall score and human preference (>0.93) and establishes a reliable foundation for the Human Turing Test. On Wow-wo-val, models achieve only 17.27 on long-horizon planning and at best 68.02 on physical consistency, indicating limited spatiotemporal consistency and physical reasoning. For the Inverse Dynamic Model Turing Test, we first use an IDM to evaluate the video foundation models' execution accuracy in the real world. However, most models collapse to $\approx$ 0% success, while WoW maintains a 40.74% success rate. These findings point to a noticeable gap between the generated videos and the real world, highlighting the urgency and necessity of benchmarking World Model in Embodied AI.