Pre-training, which utilizes extensive and varied datasets, is a critical factor in the success of Large Language Models (LLMs) across numerous applications. However, the detailed makeup of these datasets is often not disclosed, leading to concerns about data security and potential misuse. This is particularly relevant when copyrighted material, still under legal protection, is used inappropriately, either intentionally or unintentionally, infringing on the rights of the authors. In this paper, we introduce a detailed framework designed to detect and assess the presence of content from potentially copyrighted books within the training datasets of LLMs. This framework also provides a confidence estimation for the likelihood of each content sample's inclusion. To validate our approach, we conduct a series of simulated experiments, the results of which affirm the framework's effectiveness in identifying and addressing instances of content misuse in LLM training processes. Furthermore, we investigate the presence of recognizable quotes from famous literary works within these datasets. The outcomes of our study have significant implications for ensuring the ethical use of copyrighted materials in the development of LLMs, highlighting the need for more transparent and responsible data management practices in this field.
OpenAI's latest large vision-language model (LVLM), GPT-4V(ision), has piqued considerable interest for its potential in medical applications. Despite its promise, recent studies and internal reviews highlight its underperformance in specialized medical tasks. This paper explores the boundary of GPT-4V's capabilities in medicine, particularly in processing complex imaging data from endoscopies, CT scans, and MRIs etc. Leveraging open-source datasets, we assessed its foundational competencies, identifying substantial areas for enhancement. Our research emphasizes prompt engineering, an often-underutilized strategy for improving AI responsiveness. Through iterative testing, we refined the model's prompts, significantly improving its interpretative accuracy and relevance in medical imaging. From our comprehensive evaluations, we distilled 10 effective prompt engineering techniques, each fortifying GPT-4V's medical acumen. These methodical enhancements facilitate more reliable, precise, and clinically valuable insights from GPT-4V, advancing its operability in critical healthcare environments. Our findings are pivotal for those employing AI in medicine, providing clear, actionable guidance on harnessing GPT-4V's full diagnostic potential.
Segment Anything Model (SAM) has achieved impressive results for natural image segmentation with input prompts such as points and bounding boxes. Its success largely owes to massive labeled training data. However, directly applying SAM to medical image segmentation cannot perform well because SAM lacks medical knowledge -- it does not use medical images for training. To incorporate medical knowledge into SAM, we introduce SA-Med2D-20M, a large-scale segmentation dataset of 2D medical images built upon numerous public and private datasets. It consists of 4.6 million 2D medical images and 19.7 million corresponding masks, covering almost the whole body and showing significant diversity. This paper describes all the datasets collected in SA-Med2D-20M and details how to process these datasets. Furthermore, comprehensive statistics of SA-Med2D-20M are presented to facilitate the better use of our dataset, which can help the researchers build medical vision foundation models or apply their models to downstream medical applications. We hope that the large scale and diversity of SA-Med2D-20M can be leveraged to develop medical artificial intelligence for enhancing diagnosis, medical image analysis, knowledge sharing, and education. The data with the redistribution license is publicly available at https://github.com/OpenGVLab/SAM-Med2D.
Although the Segment Anything Model (SAM) has demonstrated impressive performance in 2D natural image segmentation, its application to 3D volumetric medical images reveals significant shortcomings, namely suboptimal performance and unstable prediction, necessitating an excessive number of prompt points to attain the desired outcomes. These issues can hardly be addressed by fine-tuning SAM on medical data because the original 2D structure of SAM neglects 3D spatial information. In this paper, we introduce SAM-Med3D, the most comprehensive study to modify SAM for 3D medical images. Our approach is characterized by its comprehensiveness in two primary aspects: firstly, by comprehensively reformulating SAM to a thorough 3D architecture trained on a comprehensively processed large-scale volumetric medical dataset; and secondly, by providing a comprehensive evaluation of its performance. Specifically, we train SAM-Med3D with over 131K 3D masks and 247 categories. Our SAM-Med3D excels at capturing 3D spatial information, exhibiting competitive performance with significantly fewer prompt points than the top-performing fine-tuned SAM in the medical domain. We then evaluate its capabilities across 15 datasets and analyze it from multiple perspectives, including anatomical structures, modalities, targets, and generalization abilities. Our approach, compared with SAM, showcases pronouncedly enhanced efficiency and broad segmentation capabilities for 3D volumetric medical images. Our code is released at https://github.com/uni-medical/SAM-Med3D.
Modern language models (LMs) have been successfully employed in source code generation and understanding, leading to a significant increase in research focused on learning-based code intelligence, such as automated bug repair, and test case generation. Despite their great potential, language models for code intelligence (LM4Code) are susceptible to potential pitfalls, which hinder realistic performance and further impact their reliability and applicability in real-world deployment. Such challenges drive the need for a comprehensive understanding - not just identifying these issues but delving into their possible implications and existing solutions to build more reliable language models tailored to code intelligence. Based on a well-defined systematic research approach, we conducted an extensive literature review to uncover the pitfalls inherent in LM4Code. Finally, 67 primary studies from top-tier venues have been identified. After carefully examining these studies, we designed a taxonomy of pitfalls in LM4Code research and conducted a systematic study to summarize the issues, implications, current solutions, and challenges of different pitfalls for LM4Code systems. We developed a comprehensive classification scheme that dissects pitfalls across four crucial aspects: data collection and labeling, system design and learning, performance evaluation, and deployment and maintenance. Through this study, we aim to provide a roadmap for researchers and practitioners, facilitating their understanding and utilization of LM4Code in reliable and trustworthy ways.
We do not pursue a novel method in this paper, but aim to study if a modern text-to-image diffusion model can tailor any task-adaptive image classifier across domains and categories. Existing domain adaptive image classification works exploit both source and target data for domain alignment so as to transfer the knowledge learned from the labeled source data to the unlabeled target data. However, as the development of the text-to-image diffusion model, we wonder if the high-fidelity synthetic data from the text-to-image generator can serve as a surrogate of the source data in real world. In this way, we do not need to collect and annotate the source data for each domain adaptation task in a one-for-one manner. Instead, we utilize only one off-the-shelf text-to-image model to synthesize images with category labels derived from the corresponding text prompts, and then leverage the surrogate data as a bridge to transfer the knowledge embedded in the task-agnostic text-to-image generator to the task-oriented image classifier via domain adaptation. Such a one-for-all adaptation paradigm allows us to adapt anything in the world using only one text-to-image generator as well as the corresponding unlabeled target data. Extensive experiments validate the feasibility of the proposed idea, which even surpasses the state-of-the-art domain adaptation works using the source data collected and annotated in real world.
Privacy concerns have led to a surge in the creation of synthetic datasets, with diffusion models emerging as a promising avenue. Although prior studies have performed empirical evaluations on these models, there has been a gap in providing a mathematical characterization of their privacy-preserving capabilities. To address this, we present the pioneering theoretical exploration of the privacy preservation inherent in discrete diffusion models (DDMs) for discrete dataset generation. Focusing on per-instance differential privacy (pDP), our framework elucidates the potential privacy leakage for each data point in a given training dataset, offering insights into data preprocessing to reduce privacy risks of the synthetic dataset generation via DDMs. Our bounds also show that training with $s$-sized data points leads to a surge in privacy leakage from $(\epsilon, \mathcal{O}(\frac{1}{s^2\epsilon}))$-pDP to $(\epsilon, \mathcal{O}(\frac{1}{s\epsilon}))$-pDP during the transition from the pure noise to the synthetic clean data phase, and a faster decay in diffusion coefficients amplifies the privacy guarantee. Finally, we empirically verify our theoretical findings on both synthetic and real-world datasets.
Mixed-integer linear programming (MILP) stands as a notable NP-hard problem pivotal to numerous crucial industrial applications. The development of effective algorithms, the tuning of solvers, and the training of machine learning models for MILP resolution all hinge on access to extensive, diverse, and representative data. Yet compared to the abundant naturally occurring data in image and text realms, MILP is markedly data deficient, underscoring the vital role of synthetic MILP generation. We present DIG-MILP, a deep generative framework based on variational auto-encoder (VAE), adept at extracting deep-level structural features from highly limited MILP data and producing instances that closely mirror the target data. Notably, by leveraging the MILP duality, DIG-MILP guarantees a correct and complete generation space as well as ensures the boundedness and feasibility of the generated instances. Our empirical study highlights the novelty and quality of the instances generated by DIG-MILP through two distinct downstream tasks: (S1) Data sharing, where solver solution times correlate highly positive between original and DIG-MILP-generated instances, allowing data sharing for solver tuning without publishing the original data; (S2) Data Augmentation, wherein the DIG-MILP-generated instances bolster the generalization performance of machine learning models tasked with resolving MILP problems.