Abstract:Precision oncology requires accurate molecular insights, yet obtaining these directly from genomics is costly and time-consuming for broad clinical use. Predicting complex molecular features and patient prognosis directly from routine whole-slide images (WSI) remains a major challenge for current deep learning methods. Here we introduce PathLUPI, which uses transcriptomic privileged information during training to extract genome-anchored histological embeddings, enabling effective molecular prediction using only WSIs at inference. Through extensive evaluation across 49 molecular oncology tasks using 11,257 cases among 20 cohorts, PathLUPI demonstrated superior performance compared to conventional methods trained solely on WSIs. Crucially, it achieves AUC $\geq$ 0.80 in 14 of the biomarker prediction and molecular subtyping tasks and C-index $\geq$ 0.70 in survival cohorts of 5 major cancer types. Moreover, PathLUPI embeddings reveal distinct cellular morphological signatures associated with specific genotypes and related biological pathways within WSIs. By effectively encoding molecular context to refine WSI representations, PathLUPI overcomes a key limitation of existing models and offers a novel strategy to bridge molecular insights with routine pathology workflows for wider clinical application.
Abstract:Point cloud analysis is the cornerstone of many downstream tasks, among which aggregating local structures is the basis for understanding point cloud data. While numerous works aggregate neighbor using three-dimensional relative coordinates, there are irrelevant point interference and feature hierarchy gap problems due to the limitation of local coordinates. Although some works address this limitation by refining spatial description though explicit modeling of cross-stage structure, these enhancement methods based on direct geometric structure encoding have problems of high computational overhead and noise sensitivity. To overcome these problems, we propose the Point Distribution Set Abstraction module (PDSA) that utilizes the correlation in the high-dimensional space to correct the feature distribution during aggregation, which improves the computational efficiency and robustness. PDSA distinguishes the point correlation based on a lightweight cross-stage structural descriptor, and enhances structural homogeneity by reducing the variance of the neighbor feature matrix and increasing classes separability though long-distance modeling. Additionally, we introducing a key point mechanism to optimize the computational overhead. The experimental result on semantic segmentation and classification tasks based on different baselines verify the generalization of the method we proposed, and achieve significant performance improvement with less parameter cost. The corresponding ablation and visualization results demonstrate the effectiveness and rationality of our method. The code and training weight is available at: https://github.com/AGENT9717/PointDistribution
Abstract:Recently, patch deformation-based methods have demonstrated significant effectiveness in multi-view stereo due to their incorporation of deformable and expandable perception for reconstructing textureless areas. However, these methods generally focus on identifying reliable pixel correlations to mitigate matching ambiguity of patch deformation, while neglecting the deformation instability caused by edge-skipping and visibility occlusions, which may cause potential estimation deviations. To address these issues, we propose DVP-MVS++, an innovative approach that synergizes both depth-normal-edge aligned and harmonized cross-view priors for robust and visibility-aware patch deformation. Specifically, to avoid edge-skipping, we first apply DepthPro, Metric3Dv2 and Roberts operator to generate coarse depth maps, normal maps and edge maps, respectively. These maps are then aligned via an erosion-dilation strategy to produce fine-grained homogeneous boundaries for facilitating robust patch deformation. Moreover, we reformulate view selection weights as visibility maps, and then implement both an enhanced cross-view depth reprojection and an area-maximization strategy to help reliably restore visible areas and effectively balance deformed patch, thus acquiring harmonized cross-view priors for visibility-aware patch deformation. Additionally, we obtain geometry consistency by adopting both aggregated normals via view selection and projection depth differences via epipolar lines, and then employ SHIQ for highlight correction to enable geometry consistency with highlight-aware perception, thus improving reconstruction quality during propagation and refinement stage. Evaluation results on ETH3D, Tanks & Temples and Strecha datasets exhibit the state-of-the-art performance and robust generalization capability of our proposed method.
Abstract:Reconstructing dynamic 3D scenes from monocular videos remains a fundamental challenge in 3D vision. While 3D Gaussian Splatting (3DGS) achieves real-time rendering in static settings, extending it to dynamic scenes is challenging due to the difficulty of learning structured and temporally consistent motion representations. This challenge often manifests as three limitations in existing methods: redundant Gaussian updates, insufficient motion supervision, and weak modeling of complex non-rigid deformations. These issues collectively hinder coherent and efficient dynamic reconstruction. To address these limitations, we propose HAIF-GS, a unified framework that enables structured and consistent dynamic modeling through sparse anchor-driven deformation. It first identifies motion-relevant regions via an Anchor Filter to suppresses redundant updates in static areas. A self-supervised Induced Flow-Guided Deformation module induces anchor motion using multi-frame feature aggregation, eliminating the need for explicit flow labels. To further handle fine-grained deformations, a Hierarchical Anchor Propagation mechanism increases anchor resolution based on motion complexity and propagates multi-level transformations. Extensive experiments on synthetic and real-world benchmarks validate that HAIF-GS significantly outperforms prior dynamic 3DGS methods in rendering quality, temporal coherence, and reconstruction efficiency.
Abstract:We present Heartcare Suite, a multimodal comprehensive framework for finegrained electrocardiogram (ECG) understanding. It comprises three key components: (i) Heartcare-220K, a high-quality, structured, and comprehensive multimodal ECG dataset covering essential tasks such as disease diagnosis, waveform morphology analysis, and rhythm interpretation. (ii) Heartcare-Bench, a systematic and multi-dimensional benchmark designed to evaluate diagnostic intelligence and guide the optimization of Medical Multimodal Large Language Models (Med-MLLMs) in ECG scenarios. and (iii) HeartcareGPT with a tailored tokenizer Bidirectional ECG Abstract Tokenization (Beat), which compresses raw multi-lead signals into semantically rich discrete tokens via duallevel vector quantization and query-guided bidirectional diffusion mechanism. Built upon Heartcare-220K, HeartcareGPT achieves strong generalization and SoTA performance across multiple clinically meaningful tasks. Extensive experiments demonstrate that Heartcare Suite is highly effective in advancing ECGspecific multimodal understanding and evaluation. Our project is available at https://github.com/Wznnnnn/Heartcare-Suite .
Abstract:Vision-Language Models (VLMs) offer a promising approach to end-to-end autonomous driving due to their human-like reasoning capabilities. However, troublesome gaps remains between current VLMs and real-world autonomous driving applications. One major limitation is that existing datasets with loosely formatted language descriptions are not machine-friendly and may introduce redundancy. Additionally, high computational cost and massive scale of VLMs hinder the inference speed and real-world deployment. To bridge the gap, this paper introduces a structured and concise benchmark dataset, NuScenes-S, which is derived from the NuScenes dataset and contains machine-friendly structured representations. Moreover, we present FastDrive, a compact VLM baseline with 0.9B parameters. In contrast to existing VLMs with over 7B parameters and unstructured language processing(e.g., LLaVA-1.5), FastDrive understands structured and concise descriptions and generates machine-friendly driving decisions with high efficiency. Extensive experiments show that FastDrive achieves competitive performance on structured dataset, with approximately 20% accuracy improvement on decision-making tasks, while surpassing massive parameter baseline in inference speed with over 10x speedup. Additionally, ablation studies further focus on the impact of scene annotations (e.g., weather, time of day) on decision-making tasks, demonstrating their importance on decision-making tasks in autonomous driving.
Abstract:Although dynamic scene reconstruction has long been a fundamental challenge in 3D vision, the recent emergence of 3D Gaussian Splatting (3DGS) offers a promising direction by enabling high-quality, real-time rendering through explicit Gaussian primitives. However, existing 3DGS-based methods for dynamic reconstruction often suffer from \textit{spatio-temporal incoherence} during initialization, where canonical Gaussians are constructed by aggregating observations from multiple frames without temporal distinction. This results in spatio-temporally entangled representations, making it difficult to model dynamic motion accurately. To overcome this limitation, we propose \textbf{STDR} (Spatio-Temporal Decoupling for Real-time rendering), a plug-and-play module that learns spatio-temporal probability distributions for each Gaussian. STDR introduces a spatio-temporal mask, a separated deformation field, and a consistency regularization to jointly disentangle spatial and temporal patterns. Extensive experiments demonstrate that incorporating our module into existing 3DGS-based dynamic scene reconstruction frameworks leads to notable improvements in both reconstruction quality and spatio-temporal consistency across synthetic and real-world benchmarks.
Abstract:Accurate indoor positioning for unmanned aerial vehicles (UAVs) is critical for logistics, surveillance, and emergency response applications, particularly in GPS-denied environments. Existing indoor localization methods, including optical tracking, ultra-wideband, and Bluetooth-based systems, face cost, accuracy, and robustness trade-offs, limiting their practicality for UAV navigation. This paper proposes CiUAV, a novel 3D indoor localization system designed for UAVs, leveraging channel state information (CSI) obtained from low-cost ESP32 IoT-based sensors. The system incorporates a dynamic automatic gain control (AGC) compensation algorithm to mitigate noise and stabilize CSI signals, significantly enhancing the robustness of the measurement. Additionally, a multi-task 3D localization model, Sensor-in-Sample (SiS), is introduced to enhance system robustness by addressing challenges related to incomplete sensor data and limited training samples. SiS achieves this by joint training with varying sensor configurations and sample sizes, ensuring reliable performance even in resource-constrained scenarios. Experiment results demonstrate that CiUAV achieves a LMSE localization error of 0.2629 m in a 3D space, achieving good accuracy and robustness. The proposed system provides a cost-effective and scalable solution, demonstrating its usefulness for UAV applications in resource-constrained indoor environments.
Abstract:Research interest in end-to-end autonomous driving has surged owing to its fully differentiable design integrating modular tasks, i.e. perception, prediction and planing, which enables optimization in pursuit of the ultimate goal. Despite the great potential of the end-to-end paradigm, existing methods suffer from several aspects including expensive BEV (bird's eye view) computation, action diversity, and sub-optimal decision in complex real-world scenarios. To address these challenges, we propose a novel hybrid sparse-dense diffusion policy, empowered by a Vision-Language Model (VLM), called Diff-VLA. We explore the sparse diffusion representation for efficient multi-modal driving behavior. Moreover, we rethink the effectiveness of VLM driving decision and improve the trajectory generation guidance through deep interaction across agent, map instances and VLM output. Our method shows superior performance in Autonomous Grand Challenge 2025 which contains challenging real and reactive synthetic scenarios. Our methods achieves 45.0 PDMS.
Abstract:Fashion video generation aims to synthesize temporally consistent videos from reference images of a designated character. Despite significant progress, existing diffusion-based methods only support a single reference image as input, severely limiting their capability to generate view-consistent fashion videos, especially when there are different patterns on the clothes from different perspectives. Moreover, the widely adopted motion module does not sufficiently model human body movement, leading to sub-optimal spatiotemporal consistency. To address these issues, we propose ProFashion, a fashion video generation framework leveraging multiple reference images to achieve improved view consistency and temporal coherency. To effectively leverage features from multiple reference images while maintaining a reasonable computational cost, we devise a Pose-aware Prototype Aggregator, which selects and aggregates global and fine-grained reference features according to pose information to form frame-wise prototypes, which serve as guidance in the denoising process. To further enhance motion consistency, we introduce a Flow-enhanced Prototype Instantiator, which exploits the human keypoint motion flow to guide an extra spatiotemporal attention process in the denoiser. To demonstrate the effectiveness of ProFashion, we extensively evaluate our method on the MRFashion-7K dataset we collected from the Internet. ProFashion also outperforms previous methods on the UBC Fashion dataset.