Abstract:Recent advances in large language models (LLMs) have enabled new possibilities in simulating complex physiological systems. We introduce Organ-Agents, a multi-agent framework that simulates human physiology via LLM-driven agents. Each Simulator models a specific system (e.g., cardiovascular, renal, immune). Training consists of supervised fine-tuning on system-specific time-series data, followed by reinforcement-guided coordination using dynamic reference selection and error correction. We curated data from 7,134 sepsis patients and 7,895 controls, generating high-resolution trajectories across 9 systems and 125 variables. Organ-Agents achieved high simulation accuracy on 4,509 held-out patients, with per-system MSEs <0.16 and robustness across SOFA-based severity strata. External validation on 22,689 ICU patients from two hospitals showed moderate degradation under distribution shifts with stable simulation. Organ-Agents faithfully reproduces critical multi-system events (e.g., hypotension, hyperlactatemia, hypoxemia) with coherent timing and phase progression. Evaluation by 15 critical care physicians confirmed realism and physiological plausibility (mean Likert ratings 3.9 and 3.7). Organ-Agents also enables counterfactual simulations under alternative sepsis treatment strategies, generating trajectories and APACHE II scores aligned with matched real-world patients. In downstream early warning tasks, classifiers trained on synthetic data showed minimal AUROC drops (<0.04), indicating preserved decision-relevant patterns. These results position Organ-Agents as a credible, interpretable, and generalizable digital twin for precision diagnosis, treatment simulation, and hypothesis testing in critical care.
Abstract:Vision transformers (ViTs) have recently been widely applied to 3D point cloud understanding, with masked autoencoding as the predominant pre-training paradigm. However, the challenge of learning dense and informative semantic features from point clouds via standard ViTs remains underexplored. We propose MaskClu, a novel unsupervised pre-training method for ViTs on 3D point clouds that integrates masked point modeling with clustering-based learning. MaskClu is designed to reconstruct both cluster assignments and cluster centers from masked point clouds, thus encouraging the model to capture dense semantic information. Additionally, we introduce a global contrastive learning mechanism that enhances instance-level feature learning by contrasting different masked views of the same point cloud. By jointly optimizing these complementary objectives, i.e., dense semantic reconstruction, and instance-level contrastive learning. MaskClu enables ViTs to learn richer and more semantically meaningful representations from 3D point clouds. We validate the effectiveness of our method via multiple 3D tasks, including part segmentation, semantic segmentation, object detection, and classification, where MaskClu sets new competitive results. The code and models will be released at:https://github.com/Amazingren/maskclu.
Abstract:Video instance segmentation (VIS) has gained significant attention for its capability in tracking and segmenting object instances across video frames. However, most of the existing VIS approaches unrealistically assume that the categories of object instances remain fixed over time. Moreover, they experience catastrophic forgetting of old classes when required to continuously learn object instances belonging to new categories. To resolve these challenges, we develop a novel Hierarchical Visual Prompt Learning (HVPL) model that overcomes catastrophic forgetting of previous categories from both frame-level and video-level perspectives. Specifically, to mitigate forgetting at the frame level, we devise a task-specific frame prompt and an orthogonal gradient correction (OGC) module. The OGC module helps the frame prompt encode task-specific global instance information for new classes in each individual frame by projecting its gradients onto the orthogonal feature space of old classes. Furthermore, to address forgetting at the video level, we design a task-specific video prompt and a video context decoder. This decoder first embeds structural inter-class relationships across frames into the frame prompt features, and then propagates task-specific global video contexts from the frame prompt features to the video prompt. Through rigorous comparisons, our HVPL model proves to be more effective than baseline approaches. The code is available at https://github.com/JiahuaDong/HVPL.
Abstract:We propose a novel spatial-temporal graph Mamba (STG-Mamba) for the music-guided dance video synthesis task, i.e., to translate the input music to a dance video. STG-Mamba consists of two translation mappings: music-to-skeleton translation and skeleton-to-video translation. In the music-to-skeleton translation, we introduce a novel spatial-temporal graph Mamba (STGM) block to effectively construct skeleton sequences from the input music, capturing dependencies between joints in both the spatial and temporal dimensions. For the skeleton-to-video translation, we propose a novel self-supervised regularization network to translate the generated skeletons, along with a conditional image, into a dance video. Lastly, we collect a new skeleton-to-video translation dataset from the Internet, containing 54,944 video clips. Extensive experiments demonstrate that STG-Mamba achieves significantly better results than existing methods.
Abstract:Continual Test Time Adaptation (CTTA) is a task that requires a source pre-trained model to continually adapt to new scenarios with changing target distributions. Existing CTTA methods primarily focus on mitigating the challenges of catastrophic forgetting and error accumulation. Though there have been emerging methods based on forgetting adaptation with parameter-efficient fine-tuning, they still struggle to balance competitive performance and efficient model adaptation, particularly in complex tasks like semantic segmentation. In this paper, to tackle the above issues, we propose a novel pipeline, Orthogonal Projection Subspace to aggregate online Prior-knowledge, dubbed OoPk. Specifically, we first project a tuning subspace orthogonally which allows the model to adapt to new domains while preserving the knowledge integrity of the pre-trained source model to alleviate catastrophic forgetting. Then, we elaborate an online prior-knowledge aggregation strategy that employs an aggressive yet efficient image masking strategy to mimic potential target dynamism, enhancing the student model's domain adaptability. This further gradually ameliorates the teacher model's knowledge, ensuring high-quality pseudo labels and reducing error accumulation. We demonstrate our method with extensive experiments that surpass previous CTTA methods and achieve competitive performances across various continual TTA benchmarks in semantic segmentation tasks.
Abstract:3D Gaussian Splatting (3DGS) serves as a highly performant and efficient encoding of scene geometry, appearance, and semantics. Moreover, grounding language in 3D scenes has proven to be an effective strategy for 3D scene understanding. Current Language Gaussian Splatting line of work fall into three main groups: (i) per-scene optimization-based, (ii) per-scene optimization-free, and (iii) generalizable approach. However, most of them are evaluated only on rendered 2D views of a handful of scenes and viewpoints close to the training views, limiting ability and insight into holistic 3D understanding. To address this gap, we propose the first large-scale benchmark that systematically assesses these three groups of methods directly in 3D space, evaluating on 1060 scenes across three indoor datasets and one outdoor dataset. Benchmark results demonstrate a clear advantage of the generalizable paradigm, particularly in relaxing the scene-specific limitation, enabling fast feed-forward inference on novel scenes, and achieving superior segmentation performance. We further introduce GaussianWorld-49K a carefully curated 3DGS dataset comprising around 49K diverse indoor and outdoor scenes obtained from multiple sources, with which we demonstrate the generalizable approach could harness strong data priors. Our codes, benchmark, and datasets will be made public to accelerate research in generalizable 3DGS scene understanding.
Abstract:Large Multimodal Models (LMMs) have achieved impressive progress in visual perception and reasoning. However, when confronted with visually ambiguous or non-semantic scene text, they often struggle to accurately spot and understand the content, frequently generating semantically plausible yet visually incorrect answers, which we refer to as semantic hallucination. In this work, we investigate the underlying causes of semantic hallucination and identify a key finding: Transformer layers in LLM with stronger attention focus on scene text regions are less prone to producing semantic hallucinations. Thus, we propose a training-free semantic hallucination mitigation framework comprising two key components: (1) ZoomText, a coarse-to-fine strategy that identifies potential text regions without external detectors; and (2) Grounded Layer Correction, which adaptively leverages the internal representations from layers less prone to hallucination to guide decoding, correcting hallucinated outputs for non-semantic samples while preserving the semantics of meaningful ones. To enable rigorous evaluation, we introduce TextHalu-Bench, a benchmark of over 1,730 samples spanning both semantic and non-semantic cases, with manually curated question-answer pairs designed to probe model hallucinations. Extensive experiments demonstrate that our method not only effectively mitigates semantic hallucination but also achieves strong performance on public benchmarks for scene text spotting and understanding.
Abstract:Visual texts embedded in videos carry rich semantic information, which is crucial for both holistic video understanding and fine-grained reasoning about local human actions. However, existing video understanding benchmarks largely overlook textual information, while OCR-specific benchmarks are constrained to static images, limiting their ability to capture the interaction between text and dynamic visual contexts. To address this gap, we propose VidText, a new benchmark designed for comprehensive and in-depth evaluation of video text understanding. VidText offers the following key features: 1) It covers a wide range of real-world scenarios and supports multilingual content, encompassing diverse settings where video text naturally appears. 2) It introduces a hierarchical evaluation framework with video-level, clip-level, and instance-level tasks, enabling assessment of both global summarization and local retrieval capabilities. 3) The benchmark also introduces a set of paired perception reasoning tasks, ranging from visual text perception to cross-modal reasoning between textual and visual information. Extensive experiments on 18 state-of-the-art Large Multimodal Models (LMMs) reveal that current models struggle across most tasks, with significant room for improvement. Further analysis highlights the impact of both model-intrinsic factors, such as input resolution and OCR capability, and external factors, including the use of auxiliary information and Chain-of-Thought reasoning strategies. We hope VidText will fill the current gap in video understanding benchmarks and serve as a foundation for future research on multimodal reasoning with video text in dynamic environments.
Abstract:While virtual try-on (VTON) systems aim to render a garment onto a target person image, this paper tackles the novel task of virtual try-off (VTOFF), which addresses the inverse problem: generating standardized product images of garments from real-world photos of clothed individuals. Unlike VTON, which must resolve diverse pose and style variations, VTOFF benefits from a consistent and well-defined output format -- typically a flat, lay-down-style representation of the garment -- making it a promising tool for data generation and dataset enhancement. However, existing VTOFF approaches face two major limitations: (i) difficulty in disentangling garment features from occlusions and complex poses, often leading to visual artifacts, and (ii) restricted applicability to single-category garments (e.g., upper-body clothes only), limiting generalization. To address these challenges, we present Text-Enhanced MUlti-category Virtual Try-Off (TEMU-VTOFF), a novel architecture featuring a dual DiT-based backbone with a modified multimodal attention mechanism for robust garment feature extraction. Our architecture is designed to receive garment information from multiple modalities like images, text, and masks to work in a multi-category setting. Finally, we propose an additional alignment module to further refine the generated visual details. Experiments on VITON-HD and Dress Code datasets show that TEMU-VTOFF sets a new state-of-the-art on the VTOFF task, significantly improving both visual quality and fidelity to the target garments.
Abstract:Instruction-based image editing models offer increased personalization opportunities in generative tasks. However, properly evaluating their results is challenging, and most of the existing metrics lag in terms of alignment with human judgment and explainability. To tackle these issues, we introduce DICE (DIfference Coherence Estimator), a model designed to detect localized differences between the original and the edited image and to assess their relevance to the given modification request. DICE consists of two key components: a difference detector and a coherence estimator, both built on an autoregressive Multimodal Large Language Model (MLLM) and trained using a strategy that leverages self-supervision, distillation from inpainting networks, and full supervision. Through extensive experiments, we evaluate each stage of our pipeline, comparing different MLLMs within the proposed framework. We demonstrate that DICE effectively identifies coherent edits, effectively evaluating images generated by different editing models with a strong correlation with human judgment. We publicly release our source code, models, and data.