Non-volatile Programmable Photonic Integrated Circuits using Mechanically Latched MEMS: A System-Level Scheme Enabling Power-Connection-Free Operation Without Performance Compromise

Programmable photonic integrated circuits (PPICs) offer a versatile platform for implementing diverse optical functions on a generic hardware mesh. However, the scalability of PPICs faces critical power consumption barriers. Therefore, we propose a novel non-volatile PPIC architecture utilizing MEMS with mechanical latching, enabling stable passive operation without any power connection once configured. To ensure practical applicability, we present a system-level solution including both this hardware innovation and an accompanying automatic error-resilient configuration algorithm. The algorithm compensates for the lack of continuous tunability inherent in the non-volatile hardware design, thereby enabling such new operational paradigm without compromising performance, and also ensuring robustness against fabrication errors. Functional simulations were performed to validate the proposed scheme by configuring five distinct functionalities of varying complexity, including a Mach-Zehnder interferometer (MZI), a MZI lattice filter, a ring resonator (ORR), a double ORR ring-loaded MZI, and a triple ORR coupled resonator waveguide filter. The results demonstrate that our non-volatile scheme achieves performance equivalent to conventional PPICs. Robustness analysis was also conducted, and the results demonstrated that our scheme exhibits strong robustness against various fabrication errors. Furthermore, we explored the trade-off between the hardware design complexity of such non-volatile scheme and its performance. This study establishes a viable pathway to a new generation of power-connection-free PPICs, providing a practical and scalable solution for future photonic systems.

From Evidence-Based Medicine to Knowledge Graph: Retrieval-Augmented Generation for Sports Rehabilitation and a Domain Benchmark

In medicine, large language models (LLMs) increasingly rely on retrieval-augmented generation (RAG) to ground outputs in up-to-date external evidence. However, current RAG approaches focus primarily on performance improvements while overlooking evidence-based medicine (EBM) principles. This study addresses two key gaps: (1) the lack of PICO alignment between queries and retrieved evidence, and (2) the absence of evidence hierarchy considerations during reranking. We present a generalizable strategy for adapting EBM to graph-based RAG, integrating the PICO framework into knowledge graph construction and retrieval, and proposing a Bayesian-inspired reranking algorithm to calibrate ranking scores by evidence grade without introducing predefined weights. We validated this framework in sports rehabilitation, a literature-rich domain currently lacking RAG systems and benchmarks. We released a knowledge graph (357,844 nodes and 371,226 edges) and a reusable benchmark of 1,637 QA pairs. The system achieved 0.830 nugget coverage, 0.819 answer faithfulness, 0.882 semantic similarity, and 0.788 PICOT match accuracy. In a 5-point Likert evaluation, five expert clinicians rated the system 4.66-4.84 across factual accuracy, faithfulness, relevance, safety, and PICO alignment. These findings demonstrate that the proposed EBM adaptation strategy improves retrieval and answer quality and is transferable to other clinical domains. The released resources also help address the scarcity of RAG datasets in sports rehabilitation.

Heteroscedastic Bayesian Optimization-Based Dynamic PID Tuning for Accurate and Robust UAV Trajectory Tracking

Unmanned Aerial Vehicles (UAVs) play an important role in various applications, where precise trajectory tracking is crucial. However, conventional control algorithms for trajectory tracking often exhibit limited performance due to the underactuated, nonlinear, and highly coupled dynamics of quadrotor systems. To address these challenges, we propose HBO-PID, a novel control algorithm that integrates the Heteroscedastic Bayesian Optimization (HBO) framework with the classical PID controller to achieve accurate and robust trajectory tracking. By explicitly modeling input-dependent noise variance, the proposed method can better adapt to dynamic and complex environments, and therefore improve the accuracy and robustness of trajectory tracking. To accelerate the convergence of optimization, we adopt a two-stage optimization strategy that allow us to more efficiently find the optimal controller parameters. Through experiments in both simulation and real-world scenarios, we demonstrate that the proposed method significantly outperforms state-of-the-art (SOTA) methods. Compared to SOTA methods, it improves the position accuracy by 24.7% to 42.9%, and the angular accuracy by 40.9% to 78.4%.

Enabling Ultra-Fast Cardiovascular Imaging Across Heterogeneous Clinical Environments with a Generalist Foundation Model and Multimodal Database

Multimodal cardiovascular magnetic resonance (CMR) imaging provides comprehensive and non-invasive insights into cardiovascular disease (CVD) diagnosis and underlying mechanisms. Despite decades of advancements, its widespread clinical adoption remains constrained by prolonged scan times and heterogeneity across medical environments. This underscores the urgent need for a generalist reconstruction foundation model for ultra-fast CMR imaging, one capable of adapting across diverse imaging scenarios and serving as the essential substrate for all downstream analyses. To enable this goal, we curate MMCMR-427K, the largest and most comprehensive multimodal CMR k-space database to date, comprising 427,465 multi-coil k-space data paired with structured metadata across 13 international centers, 12 CMR modalities, 15 scanners, and 17 CVD categories in populations across three continents. Building on this unprecedented resource, we introduce CardioMM, a generalist reconstruction foundation model capable of dynamically adapting to heterogeneous fast CMR imaging scenarios. CardioMM unifies semantic contextual understanding with physics-informed data consistency to deliver robust reconstructions across varied scanners, protocols, and patient presentations. Comprehensive evaluations demonstrate that CardioMM achieves state-of-the-art performance in the internal centers and exhibits strong zero-shot generalization to unseen external settings. Even at imaging acceleration up to 24x, CardioMM reliably preserves key cardiac phenotypes, quantitative myocardial biomarkers, and diagnostic image quality, enabling a substantial increase in CMR examination throughput without compromising clinical integrity. Together, our open-access MMCMR-427K database and CardioMM framework establish a scalable pathway toward high-throughput, high-quality, and clinically accessible cardiovascular imaging.

Kling-Omni Technical Report

We present Kling-Omni, a generalist generative framework designed to synthesize high-fidelity videos directly from multimodal visual language inputs. Adopting an end-to-end perspective, Kling-Omni bridges the functional separation among diverse video generation, editing, and intelligent reasoning tasks, integrating them into a holistic system. Unlike disjointed pipeline approaches, Kling-Omni supports a diverse range of user inputs, including text instructions, reference images, and video contexts, processing them into a unified multimodal representation to deliver cinematic-quality and highly-intelligent video content creation. To support these capabilities, we constructed a comprehensive data system that serves as the foundation for multimodal video creation. The framework is further empowered by efficient large-scale pre-training strategies and infrastructure optimizations for inference. Comprehensive evaluations reveal that Kling-Omni demonstrates exceptional capabilities in in-context generation, reasoning-based editing, and multimodal instruction following. Moving beyond a content creation tool, we believe Kling-Omni is a pivotal advancement toward multimodal world simulators capable of perceiving, reasoning, generating and interacting with the dynamic and complex worlds.

CogniEdit: Dense Gradient Flow Optimization for Fine-Grained Image Editing

Instruction-based image editing with diffusion models has achieved impressive results, yet existing methods struggle with fine-grained instructions specifying precise attributes such as colors, positions, and quantities. While recent approaches employ Group Relative Policy Optimization (GRPO) for alignment, they optimize only at individual sampling steps, providing sparse feedback that limits trajectory-level control. We propose a unified framework CogniEdit, combining multi-modal reasoning with dense reward optimization that propagates gradients across consecutive denoising steps, enabling trajectory-level gradient flow through the sampling process. Our method comprises three components: (1) Multi-modal Large Language Models for decomposing complex instructions into actionable directives, (2) Dynamic Token Focus Relocation that adaptively emphasizes fine-grained attributes, and (3) Dense GRPO-based optimization that propagates gradients across consecutive steps for trajectory-level supervision. Extensive experiments on benchmark datasets demonstrate that our CogniEdit achieves state-of-the-art performance in balancing fine-grained instruction following with visual quality and editability preservation

COMPARE: Clinical Optimization with Modular Planning and Assessment via RAG-Enhanced AI-OCT: Superior Decision Support for Percutaneous Coronary Intervention Compared to ChatGPT-5 and Junior Operators

Background: While intravascular imaging, particularly optical coherence tomography (OCT), improves percutaneous coronary intervention (PCI) outcomes, its interpretation is operator-dependent. General-purpose artificial intelligence (AI) shows promise but lacks domain-specific reliability. We evaluated the performance of CA-GPT, a novel large model deployed on an AI-OCT system, against that of the general-purpose ChatGPT-5 and junior physicians for OCT-guided PCI planning and assessment. Methods: In this single-center analysis of 96 patients who underwent OCT-guided PCI, the procedural decisions generated by the CA-GPT, ChatGPT-5, and junior physicians were compared with an expert-derived procedural record. Agreement was assessed using ten pre-specified metrics across pre-PCI and post-PCI phases. Results: For pre-PCI planning, CA-GPT demonstrated significantly higher median agreement scores (5[IQR 3.75-5]) compared to both ChatGPT-5 (3[2-4], P<0.001) and junior physicians (4[3-4], P<0.001). CA-GPT significantly outperformed ChatGPT-5 across all individual pre-PCI metrics and showed superior performance to junior physicians in stent diameter (90.3% vs. 72.2%, P<0.05) and length selection (80.6% vs. 52.8%, P<0.01). In post-PCI assessment, CA-GPT maintained excellent overall agreement (5[4.75-5]), significantly higher than both ChatGPT-5 (4[4-5], P<0.001) and junior physicians (5[4-5], P<0.05). Subgroup analysis confirmed CA-GPT's robust performance advantage in complex scenarios. Conclusion: The CA-GPT-based AI-OCT system achieved superior decision-making agreement versus a general-purpose large language model and junior physicians across both PCI planning and assessment phases. This approach provides a standardized and reliable method for intravascular imaging interpretation, demonstrating significant potential to augment operator expertise and optimize OCT-guided PCI.

IPR-1: Interactive Physical Reasoner

Humans learn by observing, interacting with environments, and internalizing physics and causality. Here, we aim to ask whether an agent can similarly acquire human-like reasoning from interaction and keep improving with more experience. We study this in a Game-to-Unseen (G2U) setting, curating 1,000+ heterogeneous games with diverse physical and causal mechanisms, and evaluate at three human-like levels: Survival, Curiosity, Utility, from primitive intuition to goal-driven reasoning. Our analysis reveals complementary failures: VLM/VLA agents reason but lack look-ahead in interactive settings, while world models imagine but imitate visual patterns rather than analyze physics and causality. We therefore propose IPR (Interactive Physical Reasoner), using world-model rollouts to score and reinforce a VLM's policy, and introduce PhysCode, a physics-centric action code aligning semantic intent with dynamics to provide a shared action space for prediction and reasoning. Pretrained on 1,000+ games, our IPR performs robustly on three levels, matches GPT-5 overall, and surpasses it on Curiosity. We find that performance improves with more training games and interaction steps, and that the model also zero-shot transfers to unseen games. These results support physics-centric interaction as a path to steadily improving physical reasoning.

A Novel Multi-Reference-Point Modeling Framework for Monostatic Background Channel: Toward 3GPP ISAC Standardization

Integrated Sensing and Communication (ISAC) has been identified as a key 6G application by ITU and 3GPP. A realistic, standard-compatible channel model is essential for ISAC system design. To characterize the impact of Sensing Targets (STs), 3GPP defines ISAC channel as a combination of target and background channels, comprising multipath components related to STs and those originating solely from the environment, respectively. Although the background channel does not carry direct ST information, its accurate modeling is critical for evaluating sensing performance, especially in complex environments. Existing communication standards characterize propagation between separated transmitter (Tx) and receiver (Rx). However, modeling background channels in the ISAC monostatic mode, where the Tx and Rx are co-located, remains a pressing challenge. In this paper, we firstly conduct ISAC monostatic background channel measurements for an indoor scenario at 28 GHz. Realistic channel parameters are extracted, revealing pronounced single-hop propagation and discrete multipath distribution. Inspired by these properties, a novel stochastic model is proposed to characterizing the ISAC monostatic background channel as the superposition of sub-channels between the monostatic Tx&Rx and multiple communication Rx-like Reference Points (RPs). This model is compatible with standardizations, and a 3GPP-extended implementation framework is introduced. Finally, a genetic algorithm-based method is proposed to extract the optimal number and placement of multi-RPs. The optimization approach and modeling framework are validated by comparing measured and simulated channel parameters. Results demonstrate that the proposed model effectively captures monostatic background channel characteristics, addresses a critical gap in ISAC channel modeling, and supports 6G standardization.

Centrum: Model-based Database Auto-tuning with Minimal Distributional Assumptions

Gaussian-Process-based Bayesian optimization (GP-BO), is a prevailing model-based framework for DBMS auto-tuning. However, recent work shows GP-BO-based DBMS auto-tuners significantly outperformed auto-tuners based on SMAC, which features random forest surrogate models; such results motivate us to rethink and investigate the limitations of GP-BO in auto-tuner design. We find the fundamental assumptions of GP-BO are widely violated when modeling and optimizing DBMS performance, while tree-ensemble-BOs (e.g., SMAC) can avoid the assumption pitfalls and deliver improved tuning efficiency and effectiveness. Moreover, we argue that existing tree-ensemble-BOs restrict further advancement in DBMS auto-tuning. First, existing tree-ensemble-BOs can only achieve distribution-free point estimates, but still impose unrealistic distributional assumptions on uncertainty estimates, compromising surrogate modeling and distort the acquisition function. Second, recent advances in gradient boosting, which can further enhance surrogate modeling against vanilla GP and random forest counterparts, have rarely been applied in optimizing DBMS auto-tuners. To address these issues, we propose a novel model-based DBMS auto-tuner, Centrum. Centrum improves distribution-free point and interval estimation in surrogate modeling with a two-phase learning procedure of stochastic gradient boosting ensembles. Moreover, Centrum adopts a generalized SGBE-estimated locally-adaptive conformal prediction to facilitate a distribution-free uncertainty estimation and acquisition function. To our knowledge, Centrum is the first auto-tuner to realize distribution-freeness, enhancing BO's practicality in DBMS auto-tuning, and the first to seamlessly fuse gradient boosting ensembles and conformal inference in BO. Extensive physical and simulation experiments on two DBMSs and three workloads show Centrum outperforms 21 SOTA methods.