Abstract:Real-time recommender systems execute multi-stage cascades (retrieval, pre-processing, fine-grained ranking) under strict tail-latency SLOs, leaving only tens of milliseconds for ranking. Generative recommendation (GR) models can improve quality by consuming long user-behavior sequences, but in production their online sequence length is tightly capped by the ranking-stage P99 budget. We observe that the majority of GR tokens encode user behaviors that are independent of the item candidates, suggesting an opportunity to pre-infer a user-behavior prefix once and reuse it during ranking rather than recomputing it on the critical path. Realizing this idea at industrial scale is non-trivial: the prefix cache must survive across multiple pipeline stages before the final ranking instance is determined, the user population implies cache footprints far beyond a single device, and indiscriminate pre-inference would overload shared resources under high QPS. We present RelayGR, a production system that enables in-HBM relay-race inference for GR. RelayGR selectively pre-infers long-term user prefixes, keeps their KV caches resident in HBM over the request lifecycle, and ensures the subsequent ranking can consume them without remote fetches. RelayGR combines three techniques: 1) a sequence-aware trigger that admits only at-risk requests under a bounded cache footprint and pre-inference load, 2) an affinity-aware router that co-locates cache production and consumption by routing both the auxiliary pre-infer signal and the ranking request to the same instance, and 3) a memory-aware expander that uses server-local DRAM to capture short-term cross-request reuse while avoiding redundant reloads. We implement RelayGR on Huawei Ascend NPUs and evaluate it with real queries. Under a fixed P99 SLO, RelayGR supports up to 1.5$\times$ longer sequences and improves SLO-compliant throughput by up to 3.6$\times$.
Abstract:The rapid advancement of large language models (LLMs) and multimodal foundation models has sparked growing interest in their potential for scientific research. However, scientific intelligence encompasses a broad spectrum of abilities ranging from understanding fundamental knowledge to conducting creative discovery, and existing benchmarks remain fragmented. Most focus on narrow tasks and fail to reflect the hierarchical and multi-disciplinary nature of real scientific inquiry. We introduce \textbf{HiSciBench}, a hierarchical benchmark designed to evaluate foundation models across five levels that mirror the complete scientific workflow: \textit{Scientific Literacy} (L1), \textit{Literature Parsing} (L2), \textit{Literature-based Question Answering} (L3), \textit{Literature Review Generation} (L4), and \textit{Scientific Discovery} (L5). HiSciBench contains 8,735 carefully curated instances spanning six major scientific disciplines, including mathematics, physics, chemistry, biology, geography, and astronomy, and supports multimodal inputs including text, equations, figures, and tables, as well as cross-lingual evaluation. Unlike prior benchmarks that assess isolated abilities, HiSciBench provides an integrated, dependency-aware framework that enables detailed diagnosis of model capabilities across different stages of scientific reasoning. Comprehensive evaluations of leading models, including GPT-5, DeepSeek-R1, and several multimodal systems, reveal substantial performance gaps: while models achieve up to 69\% accuracy on basic literacy tasks, performance declines sharply to 25\% on discovery-level challenges. HiSciBench establishes a new standard for evaluating scientific Intelligence and offers actionable insights for developing models that are not only more capable but also more reliable. The benchmark will be publicly released to facilitate future research.
Abstract:Object detection models demand large-scale annotated datasets, which are costly and labor-intensive to create. This motivated Imaginary Supervised Object Detection (ISOD), where models train on synthetic images and test on real images. However, existing methods face three limitations: (1) synthetic datasets suffer from simplistic prompts, poor image quality, and weak supervision; (2) DETR-based detectors, due to their random query initialization, struggle with slow convergence and overfitting to synthetic patterns, hindering real-world generalization; (3) uniform denoising pressure promotes model overfitting to pseudo-label noise. We propose Cascade HQP-DETR to address these limitations. First, we introduce a high-quality data pipeline using LLaMA-3, Flux, and Grounding DINO to generate the FluxVOC and FluxCOCO datasets, advancing ISOD from weak to full supervision. Second, our High-Quality Proposal guided query encoding initializes object queries with image-specific priors from SAM-generated proposals and RoI-pooled features, accelerating convergence while steering the model to learn transferable features instead of overfitting to synthetic patterns. Third, our cascade denoising algorithm dynamically adjusts training weights through progressively increasing IoU thresholds across decoder layers, guiding the model to learn robust boundaries from reliable visual cues rather than overfitting to noisy labels. Trained for just 12 epochs solely on FluxVOC, Cascade HQP-DETR achieves a SOTA 61.04\% mAP@0.5 on PASCAL VOC 2007, outperforming strong baselines, with its competitive real-data performance confirming the architecture's universal applicability.
Abstract:The capability of predicting environmental dynamics underpins both biological neural systems and general embodied AI in adapting to their surroundings. Yet prevailing approaches rest on static world models that falter when confronted with novel or rare configurations. We investigate in-context environment learning (ICEL), shifting attention from zero-shot performance to the growth and asymptotic limits of the world model. Our contributions are three-fold: (1) we formalize in-context learning of a world model and identify two core mechanisms: environment recognition and environment learning; (2) we derive error upper-bounds for both mechanisms that expose how the mechanisms emerge; and (3) we empirically confirm that distinct ICL mechanisms exist in the world model, and we further investigate how data distribution and model architecture affect ICL in a manner consistent with theory. These findings demonstrate the potential of self-adapting world models and highlight the key factors behind the emergence of ICEL, most notably the necessity of long context and diverse environments.
Abstract:Weakly supervised object detection (WSOD) has attracted significant attention in recent years, as it does not require box-level annotations. State-of-the-art methods generally adopt a multi-module network, which employs WSDDN as the multiple instance detection network module and multiple instance refinement modules to refine performance. However, these approaches suffer from three key limitations. First, existing methods tend to generate pseudo GT boxes that either focus only on discriminative parts, failing to capture the whole object, or cover the entire object but fail to distinguish between adjacent intra-class instances. Second, the foundational WSDDN architecture lacks a crucial background class representation for each proposal and exhibits a large semantic gap between its branches. Third, prior methods discard ignored proposals during optimization, leading to slow convergence. To address these challenges, we first design a heatmap-guided proposal selector (HGPS) algorithm, which utilizes dual thresholds on heatmaps to pre-select proposals, enabling pseudo GT boxes to both capture the full object extent and distinguish between adjacent intra-class instances. We then present a weakly supervised basic detection network (WSBDN), which augments each proposal with a background class representation and uses heatmaps for pre-supervision to bridge the semantic gap between matrices. At last, we introduce a negative certainty supervision loss on ignored proposals to accelerate convergence. Extensive experiments on the challenging PASCAL VOC 2007 and 2012 datasets demonstrate the effectiveness of our framework. We achieve mAP/mCorLoc scores of 58.5%/81.8% on VOC 2007 and 55.6%/80.5% on VOC 2012, performing favorably against the state-of-the-art WSOD methods. Our code is publicly available at https://github.com/gyl2565309278/DTH-CP.




Abstract:The interactions between DNA, RNA, and proteins are fundamental to biological processes, as illustrated by the central dogma of molecular biology. While modern biological pre-trained models have achieved great success in analyzing these macromolecules individually, their interconnected nature remains under-explored. In this paper, we follow the guidance of the central dogma to redesign both the data and model pipeline and offer a comprehensive framework, Life-Code, that spans different biological functions. As for data flow, we propose a unified pipeline to integrate multi-omics data by reverse-transcribing RNA and reverse-translating amino acids into nucleotide-based sequences. As for the model, we design a codon tokenizer and a hybrid long-sequence architecture to encode the interactions of both coding and non-coding regions with masked modeling pre-training. To model the translation and folding process with coding sequences, Life-Code learns protein structures of the corresponding amino acids by knowledge distillation from off-the-shelf protein language models. Such designs enable Life-Code to capture complex interactions within genetic sequences, providing a more comprehensive understanding of multi-omics with the central dogma. Extensive Experiments show that Life-Code achieves state-of-the-art performance on various tasks across three omics, highlighting its potential for advancing multi-omics analysis and interpretation.
Abstract:Recently, large foundation models, including large language models (LLMs) and large vision-language models (LVLMs), have become essential tools in critical fields such as law, finance, and healthcare. As these models increasingly integrate into our daily life, it is necessary to conduct moral evaluation to ensure that their outputs align with human values and remain within moral boundaries. Previous works primarily focus on LLMs, proposing moral datasets and benchmarks limited to text modality. However, given the rapid development of LVLMs, there is still a lack of multimodal moral evaluation methods. To bridge this gap, we introduce M$^3$oralBench, the first MultiModal Moral Benchmark for LVLMs. M$^3$oralBench expands the everyday moral scenarios in Moral Foundations Vignettes (MFVs) and employs the text-to-image diffusion model, SD3.0, to create corresponding scenario images. It conducts moral evaluation across six moral foundations of Moral Foundations Theory (MFT) and encompasses tasks in moral judgement, moral classification, and moral response, providing a comprehensive assessment of model performance in multimodal moral understanding and reasoning. Extensive experiments on 10 popular open-source and closed-source LVLMs demonstrate that M$^3$oralBench is a challenging benchmark, exposing notable moral limitations in current models. Our benchmark is publicly available.




Abstract:Tracking the 6DoF pose of unknown objects in monocular RGB video sequences is crucial for robotic manipulation. However, existing approaches typically rely on accurate depth information, which is non-trivial to obtain in real-world scenarios. Although depth estimation algorithms can be employed, geometric inaccuracy can lead to failures in RGBD-based pose tracking methods. To address this challenge, we introduce GSGTrack, a novel RGB-based pose tracking framework that jointly optimizes geometry and pose. Specifically, we adopt 3D Gaussian Splatting to create an optimizable 3D representation, which is learned simultaneously with a graph-based geometry optimization to capture the object's appearance features and refine its geometry. However, the joint optimization process is susceptible to perturbations from noisy pose and geometry data. Thus, we propose an object silhouette loss to address the issue of pixel-wise loss being overly sensitive to pose noise during tracking. To mitigate the geometric ambiguities caused by inaccurate depth information, we propose a geometry-consistent image pair selection strategy, which filters out low-confidence pairs and ensures robust geometric optimization. Extensive experiments on the OnePose and HO3D datasets demonstrate the effectiveness of GSGTrack in both 6DoF pose tracking and object reconstruction.
Abstract:Proteins are fundamental components of biological systems and can be represented through various modalities, including sequences, structures, and textual descriptions. Despite the advances in deep learning and scientific large language models (LLMs) for protein research, current methodologies predominantly focus on limited specialized tasks -- often predicting one protein modality from another. These approaches restrict the understanding and generation of multimodal protein data. In contrast, large multimodal models have demonstrated potential capabilities in generating any-to-any content like text, images, and videos, thus enriching user interactions across various domains. Integrating these multimodal model technologies into protein research offers significant promise by potentially transforming how proteins are studied. To this end, we introduce HelixProtX, a system built upon the large multimodal model, aiming to offer a comprehensive solution to protein research by supporting any-to-any protein modality generation. Unlike existing methods, it allows for the transformation of any input protein modality into any desired protein modality. The experimental results affirm the advanced capabilities of HelixProtX, not only in generating functional descriptions from amino acid sequences but also in executing critical tasks such as designing protein sequences and structures from textual descriptions. Preliminary findings indicate that HelixProtX consistently achieves superior accuracy across a range of protein-related tasks, outperforming existing state-of-the-art models. By integrating multimodal large models into protein research, HelixProtX opens new avenues for understanding protein biology, thereby promising to accelerate scientific discovery.




Abstract:The area of portrait image animation, propelled by audio input, has witnessed notable progress in the generation of lifelike and dynamic portraits. Conventional methods are limited to utilizing either audios or facial key points to drive images into videos, while they can yield satisfactory results, certain issues exist. For instance, methods driven solely by audios can be unstable at times due to the relatively weaker audio signal, while methods driven exclusively by facial key points, although more stable in driving, can result in unnatural outcomes due to the excessive control of key point information. In addressing the previously mentioned challenges, in this paper, we introduce a novel approach which we named EchoMimic. EchoMimic is concurrently trained using both audios and facial landmarks. Through the implementation of a novel training strategy, EchoMimic is capable of generating portrait videos not only by audios and facial landmarks individually, but also by a combination of both audios and selected facial landmarks. EchoMimic has been comprehensively compared with alternative algorithms across various public datasets and our collected dataset, showcasing superior performance in both quantitative and qualitative evaluations. Additional visualization and access to the source code can be located on the EchoMimic project page.