E-TraMamba: A New Paradigm for Efficient Long-Term 3D Feature Tracking with Event Cameras

Event-based 3D tracking enables low-latency and high-speed perception, while existing CNN- and Transformer-based trackers struggle to capture long-range spatiotemporal dependencies in sparse, noisy event streams, especially under real-time and efficiency constraints. To address these challenges, we present E-TraMamba, the first Mamba-based framework for 3D feature tracking on event data. This new framework adopts a linear state-space model for efficient long-range modeling and integrates a lightweight affine-transform predictor to maintain stable tracking under motion blur and occlusion. We also design an effective scheme to fuse multi-scale cues -- local spatiotemporal patches, correlation maps, and positional embeddings -- into a unified representation that enables stable and smooth 3D tracking. We construct a large-scale synthetic dataset, named EvD-PointOdyssey, which is generated with monocular rendering and provides synchronized event streams, depth maps, and accurate 3D trajectories for training and evaluating event-based 3D tracking models. Extensive experiments on event-based benchmarks demonstrate that E-TraMamba achieves state-of-the-art performance, delivering over $2\times$ longer feature lifetimes under strict accuracy thresholds (e.g., 0.1 m), with higher tracked-feature ratios and lower RMSE than all baselines. These results make E-TraMamba a strong candidate for low-latency visual odometry, real-time SLAM, and interactive robotics.

Dendritic In-Context Learning in a Single-Layer Spiking Neural Network

In-context learning (ICL) operates via implicit gradient descent embedded in the forward pass of modern AI architectures -- Transformers, Mamba, state-space models, and MLPs. Capturing this capability in biologically plausible Spiking Neural Networks (SNNs) has remained an open challenge: existing SNNs fail the Garg-2022 benchmark at non-trivial task dimensions. We trace this failure to a structural assumption: prior SNN designs route adaptation through inference-time synaptic plasticity, viewing the dendritic compartment as a passive conduit for error or teacher signals. We challenge this assumption. The subthreshold dynamics of a single dendritic compartment already implement a complete online learning algorithm. By treating the compartment as the computational substrate rather than a passive conduit, we propose DendriCL -- a single-layer compartmental spiking architecture whose apical recurrence is structurally identical to leaky online Widrow-Hoff LMS. This dynamics-only update collapses the architectural depth required for general-purpose ICL to a single layer. DendriCL is uniquely seed-stable at super-dimensional Garg-2022 ICL -- where dense Transformers exhibit grokking-style instability and fail past moderate task dimension -- and a linear probe recovers the reference online-LMS trajectory directly from the apical membrane at R^2 = 0.93, showing the algorithm is structurally embedded in the dynamics rather than implicitly discovered during training. Taken together, ICL requires neither attention, depth, nor inference-time plasticity: a single compartment with online-LMS dynamics is sufficient.

BioMedVR: Confusion-Aware Mixture-of-Prompt Experts for Biomedical Visual Reprogramming

Recent advances in vision-language models (VLMs) such as CLIP have demonstrated strong generalization across natural-image domains. However, adapting these models to biomedical imaging is non-trivial: full-model fine-tuning is computationally expensive, while medical data are often scarce and exhibit subtle, fine-grained inter-class differences, making parameter-efficient adaptation particularly critical. Visual Reprogramming (VR) offers a parameter-efficient alternative by injecting learnable perturbations into the input space, but existing VR approaches for VLMs mainly focus on positive class prompts and overlook confusing negatives, leading to miscalibrated predictions in fine-grained medical scenarios. We present BioMedVR, the first VR-based framework for biomedical imaging, enabling few-shot adaptation of pretrained VLMs through compact learnable VR modules. To mitigate class confusion, we introduce a Confusion Minimization Mechanism that leverages LLM-generated confusion-aware attributes together with a Confusion-Suppression Loss to explicitly reduce false-positive alignment. Moreover, the designed Mixture-of-Prompt Experts combines a positive expert for main-class discrimination and a negative expert for confusion suppression, balanced via adaptive gating. Extensive experiments on 18 datasets, including 11 biomedical datasets and 7 natural image benchmarks, demonstrate that BioMedVR achieves superior accuracy and generalization, effectively bridging VR and VLMs in biomedical domains.

A Theory-grounded Hybrid Neural Network Integrating Complementary Estimation Mechanisms for Stable Visual Object TrackingA

Hybrid neural networks (HNNs) that integrate artificial neural networks (ANNs) with brain-inspired neural networks have achieved broad success across perception and control tasks. However, much of the current success is confined to neuron-scale hybridization, where discrete, spike-based coding fundamentally limits applicability to continuous-state estimation tasks. In neuroscience, continuous attractor neural networks (CANNs) represent continuous states through neural ensembles, pointing to a population-scale route for HNNs to address this limitation. Yet, principled methodologies for ANN-CANN integration remain largely underexplored. In this work, we propose a theory-grounded ANN-CANN hybridization framework and instantiate it as a hybrid tracking neural network (HTNN) for visual object tracking, a representative continuous-state estimation task. The framework aligns ANN response maps with CANN dynamics in the same state space, enabling the two heterogeneous branches to interact through the shared state representation. Furthermore, we uncover a functional bias-variance complementarity: data-driven ANNs provide asymptotically unbiased estimates, while CANN estimates are low-variance but temporally lagged. By operationalizing this complementarity, HTNN achieves stable and accurate tracking across nine visual tracking benchmarks, consistently outperforming single-network baselines and existing hybrid models. Notably, these performance gains are robustly maintained even under diverse environmental variations, including occlusion, motion blur, and background interference. Through this proof-of-concept study, our framework offers a generalizable foundation for advancing HNNs toward population-scale hybridization.

When Brain Networks Travel: Learning Beyond Site

Graph-based learning on functional magnetic resonance imaging (fMRI) has shown strong potential for brain network analysis. However, existing methods degrade under cross-site out-of-distribution (OOD) settings because site-conditioned confounders induce non-pathological shortcuts, while functional connectivity constructed by temporal averaging obscures transient neurodynamics, limiting generalization to unseen sites. In this paper, we propose Cross-site OOD Robust brain nEtwork (CORE), a unified framework for brain network learning across unseen sites. CORE first performs site-aware confounder decoupling to mitigate site-conditioned bias and extract a cross-site population scaffold of reproducible diagnostic connectivity edges. It then profiles transient pathway dynamics over this scaffold using lightweight temporal descriptors and organizes scaffold edges into a line graph for transferable pathway-level modeling. Finally, CORE introduces a prior-guided subject-adaptive gating mechanism that leverages scaffold-derived population priors while preserving subject-specific connectivity variability. Extensive experiments under leave-one-site-out evaluation on real-world datasets (ABIDE, REST-meta-MDD, SRPBS, and ABCD) show that CORE consistently outperforms state-of-the-art baselines, with up to 6.7% relative gain. Furthermore, CORE remains robust to atlas variations, maintaining performance gains across different brain parcellation schemes.

MorphSNN: Adaptive Graph Diffusion and Structural Plasticity for Spiking Neural Networks

Spiking Neural Networks (SNNs) currently face a critical bottleneck: while individual neurons exhibit dynamic biological properties, their macro-scopic architectures remain confined within conventional connectivity patterns that are static and hierarchical. This discrepancy between neuron-level dynamics and network-level fixed connectivity eliminates critical brain-like lateral interactions, limiting adaptability in changing environments. To address this, we propose MorphSNN, a backbone framework inspired by biological non-synaptic diffusion and structural plasticity. Specifically, we introduce a Graph Diffusion (GD)mechanism to facilitate efficient undirected signal propagation, complementing the feedforward hierarchy. Furthermore, it incorporates a Spatio-Temporal Structural Plasticity (STSP) mechanism, endowing the network with the capability for instance-specific, dynamic topological reorganization, thereby overcoming the limitations of fixed topologies. Experiments demonstrate that MorphSNN achieves state-of-the-art accuracy on static and neuromorphic datasets; for instance, it reaches 83.35% accuracy on N-Caltech101 with only 5 timesteps. More importantly, its self-evolving topology functions as an intrinsic distribution fingerprint, enabling superior Out-of- Distribution (OOD) detection without auxiliary training. The code is available at anonymous.4open.science/r/MorphSNN-B0BC.

Linguistics and Human Brain: A Perspective of Computational Neuroscience

Elucidating the language-brain relationship requires bridging the methodological gap between the abstract theoretical frameworks of linguistics and the empirical neural data of neuroscience. Serving as an interdisciplinary cornerstone, computational neuroscience formalizes the hierarchical and dynamic structures of language into testable neural models through modeling, simulation, and data analysis. This enables a computational dialogue between linguistic hypotheses and neural mechanisms. Recent advances in deep learning, particularly large language models (LLMs), have powerfully advanced this pursuit. Their high-dimensional representational spaces provide a novel scale for exploring the neural basis of linguistic processing, while the "model-brain alignment" framework offers a methodology to evaluate the biological plausibility of language-related theories.

BrainFuse: a unified infrastructure integrating realistic biological modeling and core AI methodology

Neuroscience and artificial intelligence represent distinct yet complementary pathways to general intelligence. However, amid the ongoing boom in AI research and applications, the translational synergy between these two fields has grown increasingly elusive-hampered by a widening infrastructural incompatibility: modern AI frameworks lack native support for biophysical realism, while neural simulation tools are poorly suited for gradient-based optimization and neuromorphic hardware deployment. To bridge this gap, we introduce BrainFuse, a unified infrastructure that provides comprehensive support for biophysical neural simulation and gradient-based learning. By addressing algorithmic, computational, and deployment challenges, BrainFuse exhibits three core capabilities: (1) algorithmic integration of detailed neuronal dynamics into a differentiable learning framework; (2) system-level optimization that accelerates customizable ion-channel dynamics by up to 3,000x on GPUs; and (3) scalable computation with highly compatible pipelines for neuromorphic hardware deployment. We demonstrate this full-stack design through both AI and neuroscience tasks, from foundational neuron simulation and functional cylinder modeling to real-world deployment and application scenarios. For neuroscience, BrainFuse supports multiscale biological modeling, enabling the deployment of approximately 38,000 Hodgkin-Huxley neurons with 100 million synapses on a single neuromorphic chip while consuming as low as 1.98 W. For AI, BrainFuse facilitates the synergistic application of realistic biological neuron models, demonstrating enhanced robustness to input noise and improved temporal processing endowed by complex HH dynamics. BrainFuse therefore serves as a foundational engine to facilitate cross-disciplinary research and accelerate the development of next-generation bio-inspired intelligent systems.

BMAM: Brain-inspired Multi-Agent Memory Framework

Language-model-based agents operating over extended interaction horizons face persistent challenges in preserving temporally grounded information and maintaining behavioral consistency across sessions, a failure mode we term soul erosion. We present BMAM (Brain-inspired Multi-Agent Memory), a general-purpose memory architecture that models agent memory as a set of functionally specialized subsystems rather than a single unstructured store. Inspired by cognitive memory systems, BMAM decomposes memory into episodic, semantic, salience-aware, and control-oriented components that operate at complementary time scales. To support long-horizon reasoning, BMAM organizes episodic memories along explicit timelines and retrieves evidence by fusing multiple complementary signals. Experiments on the LoCoMo benchmark show that BMAM achieves 78.45 percent accuracy under the standard long-horizon evaluation setting, and ablation analyses confirm that the hippocampus-inspired episodic memory subsystem plays a critical role in temporal reasoning.

CogniSNN: Enabling Neuron-Expandability, Pathway-Reusability, and Dynamic-Configurability with Random Graph Architectures in Spiking Neural Networks

Spiking neural networks (SNNs), regarded as the third generation of artificial neural networks, are expected to bridge the gap between artificial intelligence and computational neuroscience. However, most mainstream SNN research directly adopts the rigid, chain-like hierarchical architecture of traditional artificial neural networks (ANNs), ignoring key structural characteristics of the brain. Biological neurons are stochastically interconnected, forming complex neural pathways that exhibit Neuron-Expandability, Pathway-Reusability, and Dynamic-Configurability. In this paper, we introduce a new SNN paradigm, named Cognition-aware SNN (CogniSNN), by incorporating Random Graph Architecture (RGA). Furthermore, we address the issues of network degradation and dimensional mismatch in deep pathways by introducing an improved pure spiking residual mechanism alongside an adaptive pooling strategy. Then, we design a Key Pathway-based Learning without Forgetting (KP-LwF) approach, which selectively reuses critical neural pathways while retaining historical knowledge, enabling efficient multi-task transfer. Finally, we propose a Dynamic Growth Learning (DGL) algorithm that allows neurons and synapses to grow dynamically along the internal temporal dimension. Extensive experiments demonstrate that CogniSNN achieves performance comparable to, or even surpassing, current state-of-the-art SNNs on neuromorphic datasets and Tiny-ImageNet. The Pathway-Reusability enhances the network's continuous learning capability across different scenarios, while the dynamic growth algorithm improves robustness against interference and mitigates the fixed-timestep constraints during neuromorphic chip deployment. This work demonstrates the potential of SNNs with random graph structures in advancing brain-inspired intelligence and lays the foundation for their practical application on neuromorphic hardware.