Evaluating GPT-4 with Vision on Detection of Radiological Findings on Chest Radiographs

The study examines the application of GPT-4V, a multi-modal large language model equipped with visual recognition, in detecting radiological findings from a set of 100 chest radiographs and suggests that GPT-4V is currently not ready for real-world diagnostic usage in interpreting chest radiographs.

Learned Scanpaths Aid Blind Panoramic Video Quality Assessment

Panoramic videos have the advantage of providing an immersive and interactive viewing experience. Nevertheless, their spherical nature gives rise to various and uncertain user viewing behaviors, which poses significant challenges for panoramic video quality assessment (PVQA). In this work, we propose an end-to-end optimized, blind PVQA method with explicit modeling of user viewing patterns through visual scanpaths. Our method consists of two modules: a scanpath generator and a quality assessor. The scanpath generator is initially trained to predict future scanpaths by minimizing their expected code length and then jointly optimized with the quality assessor for quality prediction. Our blind PVQA method enables direct quality assessment of panoramic images by treating them as videos composed of identical frames. Experiments on three public panoramic image and video quality datasets, encompassing both synthetic and authentic distortions, validate the superiority of our blind PVQA model over existing methods.

Uncovering Misattributed Suicide Causes through Annotation Inconsistency Detection in Death Investigation Notes

Data accuracy is essential for scientific research and policy development. The National Violent Death Reporting System (NVDRS) data is widely used for discovering the patterns and causes of death. Recent studies suggested the annotation inconsistencies within the NVDRS and the potential impact on erroneous suicide-cause attributions. We present an empirical Natural Language Processing (NLP) approach to detect annotation inconsistencies and adopt a cross-validation-like paradigm to identify problematic instances. We analyzed 267,804 suicide death incidents between 2003 and 2020 from the NVDRS. Our results showed that incorporating the target state's data into training the suicide-crisis classifier brought an increase of 5.4% to the F-1 score on the target state's test set and a decrease of 1.1% on other states' test set. To conclude, we demonstrated the annotation inconsistencies in NVDRS's death investigation notes, identified problematic instances, evaluated the effectiveness of correcting problematic instances, and eventually proposed an NLP improvement solution.

Deep learning with noisy labels in medical prediction problems: a scoping review

Objectives: Medical research faces substantial challenges from noisy labels attributed to factors like inter-expert variability and machine-extracted labels. Despite this, the adoption of label noise management remains limited, and label noise is largely ignored. To this end, there is a critical need to conduct a scoping review focusing on the problem space. This scoping review aims to comprehensively review label noise management in deep learning-based medical prediction problems, which includes label noise detection, label noise handling, and evaluation. Research involving label uncertainty is also included. Methods: Our scoping review follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched 4 databases, including PubMed, IEEE Xplore, Google Scholar, and Semantic Scholar. Our search terms include "noisy label AND medical / healthcare / clinical", "un-certainty AND medical / healthcare / clinical", and "noise AND medical / healthcare / clinical". Results: A total of 60 papers met inclusion criteria between 2016 and 2023. A series of practical questions in medical research are investigated. These include the sources of label noise, the impact of label noise, the detection of label noise, label noise handling techniques, and their evaluation. Categorization of both label noise detection methods and handling techniques are provided. Discussion: From a methodological perspective, we observe that the medical community has been up to date with the broader deep-learning community, given that most techniques have been evaluated on medical data. We recommend considering label noise as a standard element in medical research, even if it is not dedicated to handling noisy labels. Initial experiments can start with easy-to-implement methods, such as noise-robust loss functions, weighting, and curriculum learning.

MSLM-S2ST: A Multitask Speech Language Model for Textless Speech-to-Speech Translation with Speaker Style Preservation

There have been emerging research interest and advances in speech-to-speech translation (S2ST), translating utterances from one language to another. This work proposes Multitask Speech Language Model (MSLM), which is a decoder-only speech language model trained in a multitask setting. Without reliance on text training data, our model is able to support multilingual S2ST with speaker style preserved.

An Empirical Study of Speech Language Models for Prompt-Conditioned Speech Synthesis

Speech language models (LMs) are promising for high-quality speech synthesis through in-context learning. A typical speech LM takes discrete semantic units as content and a short utterance as prompt, and synthesizes speech which preserves the content's semantics but mimics the prompt's style. However, there is no systematic understanding on how the synthesized audio is controlled by the prompt and content. In this work, we conduct an empirical study of the widely used autoregressive (AR) and non-autoregressive (NAR) speech LMs and provide insights into the prompt design and content semantic units. Our analysis reveals that heterogeneous and nonstationary prompts hurt the audio quality in contrast to the previous finding that longer prompts always lead to better synthesis. Moreover, we find that the speaker style of the synthesized audio is also affected by the content in addition to the prompt. We further show that semantic units carry rich acoustic information such as pitch, tempo, volume and speech emphasis, which might be leaked from the content to the synthesized audio.

OWSM-CTC: An Open Encoder-Only Speech Foundation Model for Speech Recognition, Translation, and Language Identification

There has been an increasing interest in large speech models that can perform multiple speech processing tasks in a single model. Such models usually adopt the encoder-decoder or decoder-only architecture due to their popularity and good performance in many domains. However, autoregressive models can be slower during inference compared to non-autoregressive models and also have potential risks of hallucination. Though prior studies observed promising results of non-autoregressive models for certain tasks at small scales, it remains unclear if they can be scaled to speech-to-text generation in diverse languages and tasks. Inspired by the Open Whisper-style Speech Model (OWSM) project, we propose OWSM-CTC, a novel encoder-only speech foundation model based on Connectionist Temporal Classification (CTC). It is trained on 180k hours of public audio data for multilingual automatic speech recognition (ASR), speech translation (ST), and language identification (LID). Compared to encoder-decoder OWSM, our OWSM-CTC achieves competitive results on ASR and up to 25% relative improvement on ST, while it is more robust and 3 to 4 times faster for inference. OWSM-CTC also improves the long-form ASR result with 20x speed-up. We will publicly release our codebase, pre-trained model, and training logs to promote open science in speech foundation models.

A survey of recent methods for addressing AI fairness and bias in biomedicine

Artificial intelligence (AI) systems have the potential to revolutionize clinical practices, including improving diagnostic accuracy and surgical decision-making, while also reducing costs and manpower. However, it is important to recognize that these systems may perpetuate social inequities or demonstrate biases, such as those based on race or gender. Such biases can occur before, during, or after the development of AI models, making it critical to understand and address potential biases to enable the accurate and reliable application of AI models in clinical settings. To mitigate bias concerns during model development, we surveyed recent publications on different debiasing methods in the fields of biomedical natural language processing (NLP) or computer vision (CV). Then we discussed the methods that have been applied in the biomedical domain to address bias. We performed our literature search on PubMed, ACM digital library, and IEEE Xplore of relevant articles published between January 2018 and December 2023 using multiple combinations of keywords. We then filtered the result of 10,041 articles automatically with loose constraints, and manually inspected the abstracts of the remaining 890 articles to identify the 55 articles included in this review. Additional articles in the references are also included in this review. We discuss each method and compare its strengths and weaknesses. Finally, we review other potential methods from the general domain that could be applied to biomedicine to address bias and improve fairness.The bias of AIs in biomedicine can originate from multiple sources. Existing debiasing methods that focus on algorithms can be categorized into distributional or algorithmic.

SpeechComposer: Unifying Multiple Speech Tasks with Prompt Composition

Recent advancements in language models have significantly enhanced performance in multiple speech-related tasks. Existing speech language models typically utilize task-dependent prompt tokens to unify various speech tasks in a single model. However, this design omits the intrinsic connections between different speech tasks, which can potentially boost the performance of each task. In this work, we propose a novel decoder-only speech language model, SpeechComposer, that can unify common speech tasks by composing a fixed set of prompt tokens. Built upon four primary tasks -- speech synthesis, speech recognition, speech language modeling, and text language modeling -- SpeechComposer can easily extend to more speech tasks via compositions of well-designed prompt tokens, like voice conversion and speech enhancement. The unification of prompt tokens also makes it possible for knowledge sharing among different speech tasks in a more structured manner. Experimental results demonstrate that our proposed SpeechComposer can improve the performance of both primary tasks and composite tasks, showing the effectiveness of the shared prompt tokens. Remarkably, the unified decoder-only model achieves a comparable and even better performance than the baselines which are expert models designed for single tasks.