CPGPrompt: Translating Clinical Guidelines into LLM-Executable Decision Support

Clinical practice guidelines (CPGs) provide evidence-based recommendations for patient care; however, integrating them into Artificial Intelligence (AI) remains challenging. Previous approaches, such as rule-based systems, face significant limitations, including poor interpretability, inconsistent adherence to guidelines, and narrow domain applicability. To address this, we develop and validate CPGPrompt, an auto-prompting system that converts narrative clinical guidelines into large language models (LLMs). Our framework translates CPGs into structured decision trees and utilizes an LLM to dynamically navigate them for patient case evaluation. Synthetic vignettes were generated across three domains (headache, lower back pain, and prostate cancer) and distributed into four categories to test different decision scenarios. System performance was assessed on both binary specialty-referral decisions and fine-grained pathway-classification tasks. The binary specialty referral classification achieved consistently strong performance across all domains (F1: 0.85-1.00), with high recall (1.00 $\pm$ 0.00). In contrast, multi-class pathway assignment showed reduced performance, with domain-specific variations: headache (F1: 0.47), lower back pain (F1: 0.72), and prostate cancer (F1: 0.77). Domain-specific performance differences reflected the structure of each guideline. The headache guideline highlighted challenges with negation handling. The lower back pain guideline required temporal reasoning. In contrast, prostate cancer pathways benefited from quantifiable laboratory tests, resulting in more reliable decision-making.

Reinforcement Learning for Monetary Policy Under Macroeconomic Uncertainty: Analyzing Tabular and Function Approximation Methods

We study how a central bank should dynamically set short-term nominal interest rates to stabilize inflation and unemployment when macroeconomic relationships are uncertain and time-varying. We model monetary policy as a sequential decision-making problem where the central bank observes macroeconomic conditions quarterly and chooses interest rate adjustments. Using publically accessible historical Federal Reserve Economic Data (FRED), we construct a linear-Gaussian transition model and implement a discrete-action Markov Decision Process with a quadratic loss reward function. We chose to compare nine different reinforcement learning style approaches against Taylor Rule and naive baselines, including tabular Q-learning variants, SARSA, Actor-Critic, Deep Q-Networks, Bayesian Q-learning with uncertainty quantification, and POMDP formulations with partial observability. Surprisingly, standard tabular Q-learning achieved the best performance (-615.13 +- 309.58 mean return), outperforming both enhanced RL methods and traditional policy rules. Our results suggest that while sophisticated RL techniques show promise for monetary policy applications, simpler approaches may be more robust in this domain, highlighting important challenges in applying modern RL to macroeconomic policy.

NVIDIA Nemotron Nano 2: An Accurate and Efficient Hybrid Mamba-Transformer Reasoning Model

We introduce Nemotron-Nano-9B-v2, a hybrid Mamba-Transformer language model designed to increase throughput for reasoning workloads while achieving state-of-the-art accuracy compared to similarly-sized models. Nemotron-Nano-9B-v2 builds on the Nemotron-H architecture, in which the majority of the self-attention layers in the common Transformer architecture are replaced with Mamba-2 layers, to achieve improved inference speed when generating the long thinking traces needed for reasoning. We create Nemotron-Nano-9B-v2 by first pre-training a 12-billion-parameter model (Nemotron-Nano-12B-v2-Base) on 20 trillion tokens using an FP8 training recipe. After aligning Nemotron-Nano-12B-v2-Base, we employ the Minitron strategy to compress and distill the model with the goal of enabling inference on up to 128k tokens on a single NVIDIA A10G GPU (22GiB of memory, bfloat16 precision). Compared to existing similarly-sized models (e.g., Qwen3-8B), we show that Nemotron-Nano-9B-v2 achieves on-par or better accuracy on reasoning benchmarks while achieving up to 6x higher inference throughput in reasoning settings like 8k input and 16k output tokens. We are releasing Nemotron-Nano-9B-v2, Nemotron-Nano12B-v2-Base, and Nemotron-Nano-9B-v2-Base checkpoints along with the majority of our pre- and post-training datasets on Hugging Face.

Facilitating Longitudinal Interaction Studies of AI Systems

UIST researchers develop tools to address user challenges. However, user interactions with AI evolve over time through learning, adaptation, and repurposing, making one time evaluations insufficient. Capturing these dynamics requires longer-term studies, but challenges in deployment, evaluation design, and data collection have made such longitudinal research difficult to implement. Our workshop aims to tackle these challenges and prepare researchers with practical strategies for longitudinal studies. The workshop includes a keynote, panel discussions, and interactive breakout groups for discussion and hands-on protocol design and tool prototyping sessions. We seek to foster a community around longitudinal system research and promote it as a more embraced method for designing, building, and evaluating UIST tools.

RaSCL: Radar to Satellite Crossview Localization

GNSS is unreliable, inaccurate, and insufficient in many real-time autonomous field applications. In this work, we present a GNSS-free global localization solution that contains a method of registering imaging radar on the ground with overhead RGB imagery, with joint optimization of relative poses from odometry and global poses from our overhead registration. Previous works have used various combinations of ground sensors and overhead imagery, and different feature extraction and matching methods. These include various handcrafted and deep-learning-based methods for extracting features from overhead imagery. Our work presents insights on extracting essential features from RGB overhead images for effective global localization against overhead imagery using only ground radar and a single georeferenced initial guess. We motivate our method by evaluating it on datasets in diverse geographic conditions and robotic platforms, including on an Unmanned Surface Vessel (USV) as well as urban and suburban driving datasets.

AGENTiGraph: An Interactive Knowledge Graph Platform for LLM-based Chatbots Utilizing Private Data

Large Language Models~(LLMs) have demonstrated capabilities across various applications but face challenges such as hallucination, limited reasoning abilities, and factual inconsistencies, especially when tackling complex, domain-specific tasks like question answering~(QA). While Knowledge Graphs~(KGs) have been shown to help mitigate these issues, research on the integration of LLMs with background KGs remains limited. In particular, user accessibility and the flexibility of the underlying KG have not been thoroughly explored. We introduce AGENTiGraph (Adaptive Generative ENgine for Task-based Interaction and Graphical Representation), a platform for knowledge management through natural language interaction. It integrates knowledge extraction, integration, and real-time visualization. AGENTiGraph employs a multi-agent architecture to dynamically interpret user intents, manage tasks, and integrate new knowledge, ensuring adaptability to evolving user requirements and data contexts. Our approach demonstrates superior performance in knowledge graph interactions, particularly for complex domain-specific tasks. Experimental results on a dataset of 3,500 test cases show AGENTiGraph significantly outperforms state-of-the-art zero-shot baselines, achieving 95.12\% accuracy in task classification and 90.45\% success rate in task execution. User studies corroborate its effectiveness in real-world scenarios. To showcase versatility, we extended AGENTiGraph to legislation and healthcare domains, constructing specialized KGs capable of answering complex queries in legal and medical contexts.

CrossTalk: Intelligent Substrates for Language-Oriented Interaction in Video-Based Communication and Collaboration

Despite the advances and ubiquity of digital communication media such as videoconferencing and virtual reality, they remain oblivious to the rich intentions expressed by users. Beyond transmitting audio, videos, and messages, we envision digital communication media as proactive facilitators that can provide unobtrusive assistance to enhance communication and collaboration. Informed by the results of a formative study, we propose three key design concepts to explore the systematic integration of intelligence into communication and collaboration, including the panel substrate, language-based intent recognition, and lightweight interaction techniques. We developed CrossTalk, a videoconferencing system that instantiates these concepts, which was found to enable a more fluid and flexible communication and collaboration experience.

Open Problems and Fundamental Limitations of Reinforcement Learning from Human Feedback

Reinforcement learning from human feedback (RLHF) is a technique for training AI systems to align with human goals. RLHF has emerged as the central method used to finetune state-of-the-art large language models (LLMs). Despite this popularity, there has been relatively little public work systematizing its flaws. In this paper, we (1) survey open problems and fundamental limitations of RLHF and related methods; (2) overview techniques to understand, improve, and complement RLHF in practice; and (3) propose auditing and disclosure standards to improve societal oversight of RLHF systems. Our work emphasizes the limitations of RLHF and highlights the importance of a multi-faceted approach to the development of safer AI systems.

Neural-guided, Bidirectional Program Search for Abstraction and Reasoning

One of the challenges facing artificial intelligence research today is designing systems capable of utilizing systematic reasoning to generalize to new tasks. The Abstraction and Reasoning Corpus (ARC) measures such a capability through a set of visual reasoning tasks. In this paper we report incremental progress on ARC and lay the foundations for two approaches to abstraction and reasoning not based in brute-force search. We first apply an existing program synthesis system called DreamCoder to create symbolic abstractions out of tasks solved so far, and show how it enables solving of progressively more challenging ARC tasks. Second, we design a reasoning algorithm motivated by the way humans approach ARC. Our algorithm constructs a search graph and reasons over this graph structure to discover task solutions. More specifically, we extend existing execution-guided program synthesis approaches with deductive reasoning based on function inverse semantics to enable a neural-guided bidirectional search algorithm. We demonstrate the effectiveness of the algorithm on three domains: ARC, 24-Game tasks, and a 'double-and-add' arithmetic puzzle.

Bidirectional Microrocker Bots with Sharp Tips Actuated by a Single Electromagnet

The recent advancements in nanoscale 3D printing and microfabrication techniques have reinvigorated research on microrobotics and nanomachines. However, precise control of the robot motion and navigation on biological environments have remained challenging to date. This work presents the first demonstration of magnetic microscale rocker robot (microrocker bot) capable of bidirectional movement on flat as well as biological surfaces, when actuated by a single compact electromagnet. The 100um by 113um by 36um robot was 3D printed via two-photon lithography and subsequently coated with a nickel (Ni) thin film. When actuated by an externally applied magnetic sawtooth field, the robot demonstrated stick-slip motion enabled by its rockers. The controllable bidirectional motion is enabled by adjusting the DC offset of the waveform, which tilts the robot and biases it towards either forward or backward motion. The microrocker bots are further equipped with sharp tips that can get engaged via application of DC-only or low frequency magnetic fields. This novel control method offers an attractive solution to replace the multiple bulky coils traditionally used for magnetic actuation and control, as well as allows for a more flexible and simple approach towards microrobotics motion control. When the frequency and offset of the sawtooth waveform are optimized, the robot travels up to 87ums (0.87 body length per second) forward and backward with minor deviance from linear trajectories. Finally, to prove the robot's capabilities in direct contact with biological environments, we demonstrate the microbot's ability to traverse forward and backward on the surface of a Dracaena Fragrans (corn plant), as well as upend on its mechanical tip.