Abstract:Skill-augmented reinforcement learning improves language agents by storing reusable procedural knowledge acquired from past experience. Existing methods typically use strong language models to analyze trajectories, generate skills, and update a retrievable skill bank during online training. However, they rarely assess whether a newly generated skill is useful before it is stored and reused. We find that this assumption is unreliable: even skills generated by proprietary frontier LLMs exhibit highly mixed utility, with many providing little benefit or even degrading performance. Once such skills enter the bank, their effects are difficult to identify, because subsequent rollout feedback is delayed and usually reflects the combined effect of multiple retrieved skills rather than the marginal contribution of any individual skill. We propose an online reinforcement learning framework for pre-storage skill validation. The framework estimates whether a candidate skill contributes useful information beyond the skills already retrieved for the current task. It uses the standard rollout budget to form two matched groups under the same task and retrieval context: base rollouts conditioned on the currently retrieved skills, and skill-augmented rollouts conditioned on the same skills plus one candidate skill induced from the base trajectories. The reward gap between these two groups estimates the candidate skill's context-dependent marginal utility, enabling the framework to promote useful skills while filtering ineffective or harmful ones without additional rollout overhead. The framework further uses this marginal-utility signal to train the policy itself as a skill generator, reducing reliance on repeated calls to proprietary models. The learned skill-generation likelihood serves as a context-dependent score for retrieval-time reranking and outdated-skill pruning as the policy evolves.
Abstract:Medical large vision-language models (Med-LVLMs) have recently achieved remarkable progress in vision-language comprehension and medical image segmentation. However, existing models still struggle to unify these two capabilities, which is essential for achieving clinically reasoning that connects visual findings with semantic interpretation. We present MedSIGHT, a unified framework that equips Med-LVLMs with structured, pixel-level understanding for grounded visual comprehension. MedSIGHT introduces a novel Region Perceiver module that produces region-centric tokens, encoding spatial information directly into representation space of the language model. We further propose a medical region codebook into the LLM vocabulary, allowing the model to generate discrete region codes as symbolic representations of anatomical and pathological regions. These codes are decoded through the Region Perceiver to reconstruct segmentation mask, achieving end-to-end spatial grounding. Lastly, MedSIGHT combines Region Perceiver, Codebook and LLM using our proposed progressive training strategy to gradually aligns these modules stably. Trained on only 72K multimodal instruction pairs, MedSIGHT achieves state-of-the-art performance across diverse imaging modalities on both medical comprehension and segmentation tasks.
Abstract:Large Language Models (LLMs) are increasingly integrated into various domains, making knowledge editing techniques crucial yet potentially hazardous. Current editing methods primarily target atomic facts, overlooking the significant risks associated with manipulating factual opinions, e.g., documented stances of public figures on societal issues. Such manipulation could reshape public images, influence elections, and alter societal views. To systematically assess this threat, we introduce the Factual Opinion Editing with Evidence (FOE) benchmark, which encompasses 261 public figures, 19 issue categories, and 2,178 complete opinion records. Our evaluations demonstrate that current editing techniques struggle significantly with factual opinions, often achieving only superficial changes while failing to preserve consistency between the edited opinion and the supporting evidence generated by the model. To address this limitation, we further propose a simple yet effective Self-Generated Evidence-Aligned method that achieves opinion-evidence alignment without relying on explicit instructions. Together, our benchmark and method provide a foundation for understanding the emerging security implications of factual opinion editing in LLMs.
Abstract:We study trajectory selection for reasoning distillation, where teacher-generated reasoning trajectories are selectively used as supervision for a student model. Existing methods rely on heuristics such as trajectory quality or model confidence, but they often overlook whether a trajectory is learnable by the student. In this paper, we present LARK, a learnability-grounded method for reasoning trajectory selection. LARK selects trajectories that the student can learn efficiently while preserving the generalization of the full training distribution. At the core of LARK is a learnability factor $ρ$, which characterizes the rate at which the student's training loss decreases. To estimate this rate efficiently and maintain generalization, we introduce a learnability proxy and a $χ^2$-regularized selection policy that balances learnability and distributional coverage, both with strong theoretical guarantees on their estimation error. Empirically, LARK consistently outperforms data selection baselines across multiple base models and reasoning tasks. Diagnostic analyses show that the LARK score predicts downstream training utility and that LARK-selected trajectories induce faster supervised fine-tuning loss reduction. Our code is available at https://github.com/Tianrun-Yu/LARK.
Abstract:Despite the strong performance of deep neural networks in modern Web and language applications, they remain vulnerable to adversarial attacks, especially transferable attacks that generate adversarial examples using surrogate models without accessing the victim model. Transferable attacks in the text domain are still under-explored, with only a few studies addressing this challenging issue, often with suboptimal results due to equal treatment of submodels or inaccurate estimation of importance scores. To address these challenges, we propose a simple yet effective paradigm for transfer-based textual adversarial attack, named SEP-Attack. Specifically, we employ the Determinantal Point Process (DPP) to generate diverse surrogate ensemble weights, representing the transferability of submodels. Using these weights, we introduce a new metric to evaluate prediction confidence scores, which in turn are used to calculate word importance scores and generate adversarial candidates. Finally, we quantify the transferability score for each candidate and select the top ones as the final transferable adversarial examples. Experiments conducted on four datasets and two real-world APIs validate the efficacy of SEP-Attack, significantly outperforming state-of-the-art baselines.
Abstract:Large language models (LLMs) have shown remarkable performance in various domains, but they are constrained by massive computational and storage costs. Quantization, an effective technique for compressing models to fit resource-limited devices while preserving generative quality, encompasses two primary methods: quantization aware training (QAT) and post-training quantization (PTQ). QAT involves additional retraining or fine-tuning, thus inevitably resulting in high training cost and making it unsuitable for LLMs. Consequently, PTQ has become the research hotspot in recent quantization methods. However, existing PTQ methods usually rely on various complex computation procedures and suffer from considerable performance degradation under low-bit quantization settings. To alleviate the above issues, we propose a simple and effective post-training quantization paradigm for LLMs, named SEPTQ. Specifically, SEPTQ first calculates the importance score for each element in the weight matrix and determines the quantization locations in a static global manner. Then it utilizes the mask matrix which represents the important locations to quantize and update the associated weights column-by-column until the appropriate quantized weight matrix is obtained. Compared with previous methods, SEPTQ simplifies the post-training quantization procedure into only two steps, and considers the effectiveness and efficiency simultaneously. Experimental results on various datasets across a suite of models ranging from millions to billions in different quantization bit-levels demonstrate that SEPTQ significantly outperforms other strong baselines, especially in low-bit quantization scenarios.




Abstract:Medical Large Vision-Language Models (Med-LVLMs) have shown promising results in clinical applications, but often suffer from hallucinated outputs due to misaligned visual understanding. In this work, we identify two fundamental limitations contributing to this issue: insufficient visual representation learning and poor visual attention alignment. To address these problems, we propose MEDALIGN, a simple, lightweight alignment distillation framework that transfers visual alignment knowledge from a domain-specific Contrastive Language-Image Pre-training (CLIP) model to Med-LVLMs. MEDALIGN introduces two distillation losses: a spatial-aware visual alignment loss based on visual token-level similarity structures, and an attention-aware distillation loss that guides attention toward diagnostically relevant regions. Extensive experiments on medical report generation and medical visual question answering (VQA) benchmarks show that MEDALIGN consistently improves both performance and interpretability, yielding more visually grounded outputs.
Abstract:Multiple instance learning (MIL) has emerged as the dominant paradigm for whole slide image (WSI) analysis in computational pathology, achieving strong diagnostic performance through patch-level feature aggregation. However, existing MIL methods face critical limitations: (1) they rely on attention mechanisms that lack causal interpretability, and (2) they fail to integrate patient demographics (age, gender, race), leading to fairness concerns across diverse populations. These shortcomings hinder clinical translation, where algorithmic bias can exacerbate health disparities. We introduce \textbf{MeCaMIL}, a causality-aware MIL framework that explicitly models demographic confounders through structured causal graphs. Unlike prior approaches treating demographics as auxiliary features, MeCaMIL employs principled causal inference -- leveraging do-calculus and collider structures -- to disentangle disease-relevant signals from spurious demographic correlations. Extensive evaluation on three benchmarks demonstrates state-of-the-art performance across CAMELYON16 (ACC/AUC/F1: 0.939/0.983/0.946), TCGA-Lung (0.935/0.979/0.931), and TCGA-Multi (0.977/0.993/0.970, five cancer types). Critically, MeCaMIL achieves superior fairness -- demographic disparity variance drops by over 65% relative reduction on average across attributes, with notable improvements for underserved populations. The framework generalizes to survival prediction (mean C-index: 0.653, +0.017 over best baseline across five cancer types). Ablation studies confirm causal graph structure is essential -- alternative designs yield 0.048 lower accuracy and 4.2x times worse fairness. These results establish MeCaMIL as a principled framework for fair, interpretable, and clinically actionable AI in digital pathology. Code will be released upon acceptance.
Abstract:Glaucoma is one of the leading causes of irreversible blindness worldwide. Glaucoma prognosis is essential for identifying at-risk patients and enabling timely intervention to prevent blindness. Many existing approaches rely on historical sequential data but are constrained by fixed-length inputs, limiting their flexibility. Additionally, traditional glaucoma prognosis methods often employ end-to-end models, which struggle with the limited size of glaucoma datasets. To address these challenges, we propose a Two-Stage Decoupling Framework (TSDF) for variable-length glaucoma prognosis. In the first stage, we employ a feature representation module that leverages self-supervised learning to aggregate multiple glaucoma datasets for training, disregarding differences in their supervisory information. This approach enables datasets of varying sizes to learn better feature representations. In the second stage, we introduce a temporal aggregation module that incorporates an attention-based mechanism to process sequential inputs of varying lengths, ensuring flexible and efficient utilization of all available data. This design significantly enhances model performance while maintaining a compact parameter size. Extensive experiments on two benchmark glaucoma datasets:the Ocular Hypertension Treatment Study (OHTS) and the Glaucoma Real-world Appraisal Progression Ensemble (GRAPE),which differ significantly in scale and clinical settings,demonstrate the effectiveness and robustness of our approach.




Abstract:Session-based recommendation aims to predict intents of anonymous users based on limited behaviors. With the ability in alleviating data sparsity, contrastive learning is prevailing in the task. However, we spot that existing contrastive learning based methods still suffer from three obstacles: (1) they overlook item-level sparsity and primarily focus on session-level sparsity; (2) they typically augment sessions using item IDs like crop, mask and reorder, failing to ensure the semantic consistency of augmented views; (3) they treat all positive-negative signals equally, without considering their varying utility. To this end, we propose a novel multi-modal adaptive contrastive learning framework called MACL for session-based recommendation. In MACL, a multi-modal augmentation is devised to generate semantically consistent views at both item and session levels by leveraging item multi-modal features. Besides, we present an adaptive contrastive loss that distinguishes varying contributions of positive-negative signals to improve self-supervised learning. Extensive experiments on three real-world datasets demonstrate the superiority of MACL over state-of-the-art methods.