TCM-GPT: Efficient Pre-training of Large Language Models for Domain Adaptation in Traditional Chinese Medicine

Pre-training and fine-tuning have emerged as a promising paradigm across various natural language processing (NLP) tasks. The effectiveness of pretrained large language models (LLM) has witnessed further enhancement, holding potential for applications in the field of medicine, particularly in the context of Traditional Chinese Medicine (TCM). However, the application of these general models to specific domains often yields suboptimal results, primarily due to challenges like lack of domain knowledge, unique objectives, and computational efficiency. Furthermore, their effectiveness in specialized domains, such as Traditional Chinese Medicine, requires comprehensive evaluation. To address the above issues, we propose a novel domain specific TCMDA (TCM Domain Adaptation) approach, efficient pre-training with domain-specific corpus. Specifically, we first construct a large TCM-specific corpus, TCM-Corpus-1B, by identifying domain keywords and retreving from general corpus. Then, our TCMDA leverages the LoRA which freezes the pretrained model's weights and uses rank decomposition matrices to efficiently train specific dense layers for pre-training and fine-tuning, efficiently aligning the model with TCM-related tasks, namely TCM-GPT-7B. We further conducted extensive experiments on two TCM tasks, including TCM examination and TCM diagnosis. TCM-GPT-7B archived the best performance across both datasets, outperforming other models by relative increments of 17% and 12% in accuracy, respectively. To the best of our knowledge, our study represents the pioneering validation of domain adaptation of a large language model with 7 billion parameters in TCM domain. We will release both TCMCorpus-1B and TCM-GPT-7B model once accepted to facilitate interdisciplinary development in TCM and NLP, serving as the foundation for further study.

ClinicalGPT: Large Language Models Finetuned with Diverse Medical Data and Comprehensive Evaluation

Large language models have exhibited exceptional performance on various Natural Language Processing (NLP) tasks, leveraging techniques such as the pre-training, and instruction fine-tuning. Despite these advances, their effectiveness in medical applications is limited, due to challenges such as factual inaccuracies, reasoning abilities, and lack grounding in real-world experience. In this study, we present ClinicalGPT, a language model explicitly designed and optimized for clinical scenarios. By incorporating extensive and diverse real-world data, such as medical records, domain-specific knowledge, and multi-round dialogue consultations in the training process, ClinicalGPT is better prepared to handle multiple clinical task. Furthermore, we introduce a comprehensive evaluation framework that includes medical knowledge question-answering, medical exams, patient consultations, and diagnostic analysis of medical records. Our results demonstrate that ClinicalGPT significantly outperforms other models in these tasks, highlighting the effectiveness of our approach in adapting large language models to the critical domain of healthcare.

VDT: An Empirical Study on Video Diffusion with Transformers

This work introduces Video Diffusion Transformer (VDT), which pioneers the use of transformers in diffusion-based video generation. It features transformer blocks with modularized temporal and spatial attention modules, allowing separate optimization of each component and leveraging the rich spatial-temporal representation inherited from transformers. VDT offers several appealing benefits. 1) It excels at capturing temporal dependencies to produce temporally consistent video frames and even simulate the dynamics of 3D objects over time. 2) It enables flexible conditioning information through simple concatenation in the token space, effectively unifying video generation and prediction tasks. 3) Its modularized design facilitates a spatial-temporal decoupled training strategy, leading to improved efficiency. Extensive experiments on video generation, prediction, and dynamics modeling (i.e., physics-based QA) tasks have been conducted to demonstrate the effectiveness of VDT in various scenarios, including autonomous driving, human action, and physics-based simulation. We hope our study on the capabilities of transformer-based video diffusion in capturing accurate temporal dependencies, handling conditioning information, and achieving efficient training will benefit future research and advance the field. Codes and models are available at https://github.com/RERV/VDT.

UniAdapter: Unified Parameter-Efficient Transfer Learning for Cross-modal Modeling

Large-scale vision-language pre-trained models have shown promising transferability to various downstream tasks. As the size of these foundation models and the number of downstream tasks grow, the standard full fine-tuning paradigm becomes unsustainable due to heavy computational and storage costs. This paper proposes UniAdapter, which unifies unimodal and multimodal adapters for parameter-efficient cross-modal adaptation on pre-trained vision-language models. Specifically, adapters are distributed to different modalities and their interactions, with the total number of tunable parameters reduced by partial weight sharing. The unified and knowledge-sharing design enables powerful cross-modal representations that can benefit various downstream tasks, requiring only 1.0%-2.0% tunable parameters of the pre-trained model. Extensive experiments on 6 cross-modal downstream benchmarks (including video-text retrieval, image-text retrieval, VideoQA, and VQA) show that in most cases, UniAdapter not only outperforms the state-of-the-arts, but even beats the full fine-tuning strategy. Particularly, on the MSRVTT retrieval task, UniAdapter achieves 49.7% recall@1 with 2.2% model parameters, outperforming the latest competitors by 2.0%. The code and models are available at https://github.com/RERV/UniAdapter.

WenLan 2.0: Make AI Imagine via a Multimodal Foundation Model

The fundamental goal of artificial intelligence (AI) is to mimic the core cognitive activities of human including perception, memory, and reasoning. Although tremendous success has been achieved in various AI research fields (e.g., computer vision and natural language processing), the majority of existing works only focus on acquiring single cognitive ability (e.g., image classification, reading comprehension, or visual commonsense reasoning). To overcome this limitation and take a solid step to artificial general intelligence (AGI), we develop a novel foundation model pre-trained with huge multimodal (visual and textual) data, which is able to be quickly adapted for a broad class of downstream cognitive tasks. Such a model is fundamentally different from the multimodal foundation models recently proposed in the literature that typically make strong semantic correlation assumption and expect exact alignment between image and text modalities in their pre-training data, which is often hard to satisfy in practice thus limiting their generalization abilities. To resolve this issue, we propose to pre-train our foundation model by self-supervised learning with weak semantic correlation data crawled from the Internet and show that state-of-the-art results can be obtained on a wide range of downstream tasks (both single-modal and cross-modal). Particularly, with novel model-interpretability tools developed in this work, we demonstrate that strong imagination ability (even with hints of commonsense) is now possessed by our foundation model. We believe our work makes a transformative stride towards AGI and will have broad impact on various AI+ fields (e.g., neuroscience and healthcare).

WenLan: Bridging Vision and Language by Large-Scale Multi-Modal Pre-Training

Multi-modal pre-training models have been intensively explored to bridge vision and language in recent years. However, most of them explicitly model the cross-modal interaction between image-text pairs, by assuming that there exists strong semantic correlation between the text and image modalities. Since this strong assumption is often invalid in real-world scenarios, we choose to implicitly model the cross-modal correlation for large-scale multi-modal pre-training, which is the focus of the Chinese project `WenLan' led by our team. Specifically, with the weak correlation assumption over image-text pairs, we propose a two-tower pre-training model called BriVL within the cross-modal contrastive learning framework. Unlike OpenAI CLIP that adopts a simple contrastive learning method, we devise a more advanced algorithm by adapting the latest method MoCo into the cross-modal scenario. By building a large queue-based dictionary, our BriVL can incorporate more negative samples in limited GPU resources. We further construct a large Chinese multi-source image-text dataset called RUC-CAS-WenLan for pre-training our BriVL model. Extensive experiments demonstrate that the pre-trained BriVL model outperforms both UNITER and OpenAI CLIP on various downstream tasks.