ADRD-Bench: A Preliminary LLM Benchmark for Alzheimer's Disease and Related Dementias

Large language models (LLMs) have shown great potential for healthcare applications. However, existing evaluation benchmarks provide minimal coverage of Alzheimer's Disease and Related Dementias (ADRD). To address this gap, we introduce ADRD-Bench, the first ADRD-specific benchmark dataset designed for rigorous evaluation of LLMs. ADRD-Bench has two components: 1) ADRD Unified QA, a synthesis of 1,352 questions consolidated from seven established medical benchmarks, providing a unified assessment of clinical knowledge; and 2) ADRD Caregiving QA, a novel set of 149 questions derived from the Aging Brain Care (ABC) program, a widely used, evidence-based brain health management program. Guided by a program with national expertise in comprehensive ADRD care, this new set was designed to mitigate the lack of practical caregiving context in existing benchmarks. We evaluated 33 state-of-the-art LLMs on the proposed ADRD-Bench. Results showed that the accuracy of open-weight general models ranged from 0.63 to 0.93 (mean: 0.78; std: 0.09). The accuracy of open-weight medical models ranged from 0.48 to 0.93 (mean: 0.82; std: 0.13). The accuracy of closed-source general models ranged from 0.83 to 0.91 (mean: 0.89; std: 0.03). While top-tier models achieved high accuracies (>0.9), case studies revealed that inconsistent reasoning quality and stability limit their reliability, highlighting a critical need for domain-specific improvement to enhance LLMs' knowledge and reasoning grounded in daily caregiving data. The entire dataset is available at https://github.com/IIRL-ND/ADRD-Bench.

Identifying Evidence-Based Nudges in Biomedical Literature with Large Language Models

We present a scalable, AI-powered system that identifies and extracts evidence-based behavioral nudges from unstructured biomedical literature. Nudges are subtle, non-coercive interventions that influence behavior without limiting choice, showing strong impact on health outcomes like medication adherence. However, identifying these interventions from PubMed's 8 million+ articles is a bottleneck. Our system uses a novel multi-stage pipeline: first, hybrid filtering (keywords, TF-IDF, cosine similarity, and a "nudge-term bonus") reduces the corpus to about 81,000 candidates. Second, we use OpenScholar (quantized LLaMA 3.1 8B) to classify papers and extract structured fields like nudge type and target behavior in a single pass, validated against a JSON schema. We evaluated four configurations on a labeled test set (N=197). The best setup (Title/Abstract/Intro) achieved a 67.0% F1 score and 72.0% recall, ideal for discovery. A high-precision variant using self-consistency (7 randomized passes) achieved 100% precision with 12% recall, demonstrating a tunable trade-off for high-trust use cases. This system is being integrated into Agile Nudge+, a real-world platform, to ground LLM-generated interventions in peer-reviewed evidence. This work demonstrates interpretable, domain-specific retrieval pipelines for evidence synthesis and personalized healthcare.

Data Science and Technology Towards AGI Part I: Tiered Data Management

The development of artificial intelligence can be viewed as an evolution of data-driven learning paradigms, with successive shifts in data organization and utilization continuously driving advances in model capability. Current LLM research is dominated by a paradigm that relies heavily on unidirectional scaling of data size, increasingly encountering bottlenecks in data availability, acquisition cost, and training efficiency. In this work, we argue that the development of AGI is entering a new phase of data-model co-evolution, in which models actively guide data management while high-quality data, in turn, amplifies model capabilities. To implement this vision, we propose a tiered data management framework, designed to support the full LLM training lifecycle across heterogeneous learning objectives and cost constraints. Specifically, we introduce an L0-L4 tiered data management framework, ranging from raw uncurated resources to organized and verifiable knowledge. Importantly, LLMs are fully used in data management processes, such as quality scoring and content editing, to refine data across tiers. Each tier is characterized by distinct data properties, management strategies, and training roles, enabling data to be strategically allocated across LLM training stages, including pre-training, mid-training, and alignment. The framework balances data quality, acquisition cost, and marginal training benefit, providing a systematic approach to scalable and sustainable data management. We validate the effectiveness of the proposed framework through empirical studies, in which tiered datasets are constructed from raw corpora and used across multiple training phases. Experimental results demonstrate that tier-aware data utilization significantly improves training efficiency and model performance. To facilitate further research, we release our tiered datasets and processing tools to the community.

Beyond Imitation: Reinforcement Learning for Active Latent Planning

Aiming at efficient and dense chain-of-thought (CoT) reasoning, latent reasoning methods fine-tune Large Language Models (LLMs) to substitute discrete language tokens with continuous latent tokens. These methods consume fewer tokens compared to the conventional language CoT reasoning and have the potential to plan in a dense latent space. However, current latent tokens are generally supervised based on imitating language labels. Considering that there can be multiple equivalent but diverse CoT labels for a question, passively imitating an arbitrary one may lead to inferior latent token representations and latent reasoning policies, undermining the potential planning ability and resulting in clear gaps between training and testing. In this work, we emphasize the importance of active planning over the representation space of latent tokens in achieving the optimal latent reasoning policy. So, we propose the \underline{A}c\underline{t}ive Latent \underline{P}lanning method (ATP-Latent), which models the supervision process of latent tokens as a conditional variational auto-encoder (VAE) to obtain a smoother latent space. Moreover, to facilitate the most reasonable latent reasoning policy, ATP-Latent conducts reinforcement learning (RL) with an auxiliary coherence reward, which is calculated based on the consistency between VAE-decoded contents of latent tokens, enabling a guided RL process. In experiments on LLaMA-1B, ATP-Latent demonstrates +4.1\% accuracy and -3.3\% tokens on four benchmarks compared to advanced baselines. Codes are available on https://github.com/zz1358m/ATP-Latent-master.

Token-level Collaborative Alignment for LLM-based Generative Recommendation

Large Language Models (LLMs) have demonstrated strong potential for generative recommendation by leveraging rich semantic knowledge. However, existing LLM-based recommender systems struggle to effectively incorporate collaborative filtering (CF) signals, due to a fundamental mismatch between item-level preference modeling in CF and token-level next-token prediction (NTP) optimization in LLMs. Prior approaches typically treat CF as contextual hints or representation bias, and resort to multi-stage training to reduce behavioral semantic space discrepancies, leaving CF unable to explicitly regulate LLM generation. In this work, we propose Token-level Collaborative Alignment for Recommendation (TCA4Rec), a model-agnostic and plug-and-play framework that establishes an explicit optimization-level interface between CF supervision and LLM generation. TCA4Rec consists of (i) Collaborative Tokenizer, which projects raw item-level CF logits into token-level distributions aligned with the LLM token space, and (ii) Soft Label Alignment, which integrates these CF-informed distributions with one-hot supervision to optimize a soft NTP objective. This design preserves the generative nature of LLM training while enabling collaborative alignment with essential user preference of CF models. We highlight TCA4Rec is compatible with arbitrary traditional CF models and generalizes across a wide range of decoder-based LLM recommender architectures. Moreover, it provides an explicit mechanism to balance behavioral alignment and semantic fluency, yielding generative recommendations that are both accurate and controllable. Extensive experiments demonstrate that TCA4Rec consistently improves recommendation performance across a broad spectrum of CF models and LLM-based recommender systems.

Self-Manager: Parallel Agent Loop for Long-form Deep Research

Long-form deep research requires multi-faceted investigations over extended horizons to get a comprehensive report. When handling such complex tasks, existing agents manage context at the subtask level to overcome linear context accumulation and information loss. However, they still adhere to a single context window and sequential execution paradigm, which results in mutual interference and blocking behavior, restricting scalability and adaptability. To address this issue, this paper introduces Self-Manager, a parallel agent loop that enables asynchronous and concurrent execution. The main thread can create multiple subthreads, each with its own isolated context, and manage them iteratively through Thread Control Blocks, allowing for more focused and flexible parallel agent execution. To assess its effectiveness, we benchmark Self-Manager on DeepResearch Bench, where it consistently outperforms existing single-agent loop baselines across all metrics. Furthermore, we conduct extensive analytical experiments to demonstrate the necessity of Self-Manager's design choices, as well as its advantages in contextual capacity, efficiency, and generalization.

VIGIL: Defending LLM Agents Against Tool Stream Injection via Verify-Before-Commit

LLM agents operating in open environments face escalating risks from indirect prompt injection, particularly within the tool stream where manipulated metadata and runtime feedback hijack execution flow. Existing defenses encounter a critical dilemma as advanced models prioritize injected rules due to strict alignment while static protection mechanisms sever the feedback loop required for adaptive reasoning. To reconcile this conflict, we propose \textbf{VIGIL}, a framework that shifts the paradigm from restrictive isolation to a verify-before-commit protocol. By facilitating speculative hypothesis generation and enforcing safety through intent-grounded verification, \textbf{VIGIL} preserves reasoning flexibility while ensuring robust control. We further introduce \textbf{SIREN}, a benchmark comprising 959 tool stream injection cases designed to simulate pervasive threats characterized by dynamic dependencies. Extensive experiments demonstrate that \textbf{VIGIL} outperforms state-of-the-art dynamic defenses by reducing the attack success rate by over 22\% while more than doubling the utility under attack compared to static baselines, thereby achieving an optimal balance between security and utility. Code is available at https://anonymous.4open.science/r/VIGIL-378B/.

DynaDebate: Breaking Homogeneity in Multi-Agent Debate with Dynamic Path Generation

Recent years have witnessed the rapid development of Large Language Model-based Multi-Agent Systems (MAS), which excel at collaborative decision-making and complex problem-solving. Recently, researchers have further investigated Multi-Agent Debate (MAD) frameworks, which enhance the reasoning and collaboration capabilities of MAS through information exchange and debate among multiple agents. However, existing approaches often rely on unguided initialization, causing agents to adopt identical reasoning paths that lead to the same errors. As a result, effective debate among agents is hindered, and the final outcome frequently degenerates into simple majority voting. To solve the above problem, in this paper, we introduce Dynamic Multi-Agent Debate (DynaDebate), which enhances the effectiveness of multi-agent debate through three key mechanisms: (1) Dynamic Path Generation and Allocation, which employs a dedicated Path Generation Agent to generate diverse and logical solution paths with adaptive redundancy; (2) Process-Centric Debate, which shifts the focus from surface-level outcome voting to rigorous step-by-step logic critique to ensure process correctness; (3) A Trigger-Based Verification Agent, which is activated upon disagreement and uses external tools to objectively resolve deadlocks. Extensive experiments demonstrate that DynaDebate achieves superior performance across various benchmarks, surpassing existing state-of-the-art MAD methods.

SofT-GRPO: Surpassing Discrete-Token LLM Reinforcement Learning via Gumbel-Reparameterized Soft-Thinking Policy Optimization

The soft-thinking paradigm for Large Language Model (LLM) reasoning can outperform the conventional discrete-token Chain-of-Thought (CoT) reasoning in some scenarios, underscoring its research and application value. However, while the discrete-token CoT reasoning pattern can be reinforced through policy optimization algorithms such as group relative policy optimization (GRPO), extending the soft-thinking pattern with Reinforcement Learning (RL) remains challenging. This difficulty stems from the complexities of injecting stochasticity into soft-thinking tokens and updating soft-thinking policies accordingly. As a result, previous attempts to combine soft-thinking with GRPO typically underperform their discrete-token GRPO counterparts. To fully unlock the potential of soft-thinking, this paper presents a novel policy optimization algorithm, SofT-GRPO, to reinforce LLMs under the soft-thinking reasoning pattern. SofT-GRPO injects the Gumbel noise into logits, employs the Gumbel-Softmax technique to avoid soft-thinking tokens outside the pre-trained embedding space, and leverages the reparameterization trick in policy gradient. We conduct experiments across base LLMs ranging from 1.5B to 7B parameters, and results demonstrate that SofT-GRPO enables soft-thinking LLMs to slightly outperform discrete-token GRPO on Pass@1 (+0.13% on average accuracy), while exhibiting a substantial uplift on Pass@32 (+2.19% on average accuracy). Codes and weights are available on https://github.com/zz1358m/SofT-GRPO-master

A2R: An Asymmetric Two-Stage Reasoning Framework for Parallel Reasoning

Recent Large Reasoning Models have achieved significant improvements in complex task-solving capabilities by allocating more computation at the inference stage with a "thinking longer" paradigm. Even as the foundational reasoning capabilities of models advance rapidly, the persistent gap between a model's performance in a single attempt and its latent potential, often revealed only across multiple solution paths, starkly highlights the disparity between its realized and inherent capabilities. To address this, we present A2R, an Asymmetric Two-Stage Reasoning framework designed to explicitly bridge the gap between a model's potential and its actual performance. In this framework, an "explorer" model first generates potential solutions in parallel through repeated sampling. Subsequently,a "synthesizer" model integrates these references for a more refined, second stage of reasoning. This two-stage process allows computation to be scaled orthogonally to existing sequential methods. Our work makes two key innovations: First, we present A2R as a plug-and-play parallel reasoning framework that explicitly enhances a model's capabilities on complex questions. For example, using our framework, the Qwen3-8B-distill model achieves a 75% performance improvement compared to its self-consistency baseline. Second, through a systematic analysis of the explorer and synthesizer roles, we identify an effective asymmetric scaling paradigm. This insight leads to A2R-Efficient, a "small-to-big" variant that combines a Qwen3-4B explorer with a Qwen3-8B synthesizer. This configuration surpasses the average performance of a monolithic Qwen3-32B model at a nearly 30% lower cost. Collectively, these results show that A2R is not only a performance-boosting framework but also an efficient and practical solution for real-world applications.