S2ST-Omni: An Efficient and Scalable Multilingual Speech-to-Speech Translation Framework via Seamlessly Speech-Text Alignment and Streaming Speech Decoder

Multilingual speech-to-speech translation (S2ST) aims to directly convert spoken utterances from multiple source languages into fluent and intelligible speech in a target language. Despite recent progress, several critical challenges persist: 1) achieving high-quality and low-latency S2ST remains a significant obstacle; 2) most existing S2ST methods rely heavily on large-scale parallel speech corpora, which are difficult and resource-intensive to obtain. To tackle these challenges, we introduce S2ST-Omni, a novel, efficient, and scalable framework tailored for multilingual speech-to-speech translation. To enable high-quality S2TT while mitigating reliance on large-scale parallel speech corpora, we leverage powerful pretrained models: Whisper for robust audio understanding and Qwen 3.0 for advanced text comprehension. A lightweight speech adapter is introduced to bridge the modality gap between speech and text representations, facilitating effective utilization of pretrained multimodal knowledge. To ensure both translation accuracy and real-time responsiveness, we adopt a streaming speech decoder in the TTS stage, which generates the target speech in an autoregressive manner. Extensive experiments conducted on the CVSS benchmark demonstrate that S2ST-Omni consistently surpasses several state-of-the-art S2ST baselines in translation quality, highlighting its effectiveness and superiority.

Curriculum Learning for Biological Sequence Prediction: The Case of De Novo Peptide Sequencing

Peptide sequencing-the process of identifying amino acid sequences from mass spectrometry data-is a fundamental task in proteomics. Non-Autoregressive Transformers (NATs) have proven highly effective for this task, outperforming traditional methods. Unlike autoregressive models, which generate tokens sequentially, NATs predict all positions simultaneously, leveraging bidirectional context through unmasked self-attention. However, existing NAT approaches often rely on Connectionist Temporal Classification (CTC) loss, which presents significant optimization challenges due to CTC's complexity and increases the risk of training failures. To address these issues, we propose an improved non-autoregressive peptide sequencing model that incorporates a structured protein sequence curriculum learning strategy. This approach adjusts protein's learning difficulty based on the model's estimated protein generational capabilities through a sampling process, progressively learning peptide generation from simple to complex sequences. Additionally, we introduce a self-refining inference-time module that iteratively enhances predictions using learned NAT token embeddings, improving sequence accuracy at a fine-grained level. Our curriculum learning strategy reduces NAT training failures frequency by more than 90% based on sampled training over various data distributions. Evaluations on nine benchmark species demonstrate that our approach outperforms all previous methods across multiple metrics and species.

Image Corruption-Inspired Membership Inference Attacks against Large Vision-Language Models

Large vision-language models (LVLMs) have demonstrated outstanding performance in many downstream tasks. However, LVLMs are trained on large-scale datasets, which can pose privacy risks if training images contain sensitive information. Therefore, it is important to detect whether an image is used to train the LVLM. Recent studies have investigated membership inference attacks (MIAs) against LVLMs, including detecting image-text pairs and single-modality content. In this work, we focus on detecting whether a target image is used to train the target LVLM. We design simple yet effective Image Corruption-Inspired Membership Inference Attacks (ICIMIA) against LLVLMs, which are inspired by LVLM's different sensitivity to image corruption for member and non-member images. We first perform an MIA method under the white-box setting, where we can obtain the embeddings of the image through the vision part of the target LVLM. The attacks are based on the embedding similarity between the image and its corrupted version. We further explore a more practical scenario where we have no knowledge about target LVLMs and we can only query the target LVLMs with an image and a question. We then conduct the attack by utilizing the output text embeddings' similarity. Experiments on existing datasets validate the effectiveness of our proposed attack methods under those two different settings.

Wi-CBR: WiFi-based Cross-domain Behavior Recognition via Multimodal Collaborative Awareness

WiFi-based human behavior recognition aims to recognize gestures and activities by analyzing wireless signal variations. However, existing methods typically focus on a single type of data, neglecting the interaction and fusion of multiple features. To this end, we propose a novel multimodal collaborative awareness method. By leveraging phase data reflecting changes in dynamic path length and Doppler Shift (DFS) data corresponding to frequency changes related to the speed of gesture movement, we enable efficient interaction and fusion of these features to improve recognition accuracy. Specifically, we first introduce a dual-branch self-attention module to capture spatial-temporal cues within each modality. Then, a group attention mechanism is applied to the concatenated phase and DFS features to mine key group features critical for behavior recognition. Through a gating mechanism, the combined features are further divided into PD-strengthen and PD-weaken branches, optimizing information entropy and promoting cross-modal collaborative awareness. Extensive in-domain and cross-domain experiments on two large publicly available datasets, Widar3.0 and XRF55, demonstrate the superior performance of our method.

Universal Biological Sequence Reranking for Improved De Novo Peptide Sequencing

De novo peptide sequencing is a critical task in proteomics. However, the performance of current deep learning-based methods is limited by the inherent complexity of mass spectrometry data and the heterogeneous distribution of noise signals, leading to data-specific biases. We present RankNovo, the first deep reranking framework that enhances de novo peptide sequencing by leveraging the complementary strengths of multiple sequencing models. RankNovo employs a list-wise reranking approach, modeling candidate peptides as multiple sequence alignments and utilizing axial attention to extract informative features across candidates. Additionally, we introduce two new metrics, PMD (Peptide Mass Deviation) and RMD (residual Mass Deviation), which offer delicate supervision by quantifying mass differences between peptides at both the sequence and residue levels. Extensive experiments demonstrate that RankNovo not only surpasses its base models used to generate training candidates for reranking pre-training, but also sets a new state-of-the-art benchmark. Moreover, RankNovo exhibits strong zero-shot generalization to unseen models whose generations were not exposed during training, highlighting its robustness and potential as a universal reranking framework for peptide sequencing. Our work presents a novel reranking strategy that fundamentally challenges existing single-model paradigms and advances the frontier of accurate de novo sequencing. Our source code is provided on GitHub.

DECT-based Space-Squeeze Method for Multi-Class Classification of Metastatic Lymph Nodes in Breast Cancer

Background: Accurate assessment of metastatic burden in axillary lymph nodes is crucial for guiding breast cancer treatment decisions, yet conventional imaging modalities struggle to differentiate metastatic burden levels and capture comprehensive lymph node characteristics. This study leverages dual-energy computed tomography (DECT) to exploit spectral-spatial information for improved multi-class classification. Purpose: To develop a noninvasive DECT-based model classifying sentinel lymph nodes into three categories: no metastasis ($N_0$), low metastatic burden ($N_{+(1-2)}$), and heavy metastatic burden ($N_{+(\geq3)}$), thereby aiding therapeutic planning. Methods: We propose a novel space-squeeze method combining two innovations: (1) a channel-wise attention mechanism to compress and recalibrate spectral-spatial features across 11 energy levels, and (2) virtual class injection to sharpen inter-class boundaries and compact intra-class variations in the representation space. Results: Evaluated on 227 biopsy-confirmed cases, our method achieved an average test AUC of 0.86 (95% CI: 0.80-0.91) across three cross-validation folds, outperforming established CNNs (VGG, ResNet, etc). The channel-wise attention and virtual class components individually improved AUC by 5.01% and 5.87%, respectively, demonstrating complementary benefits. Conclusions: The proposed framework enhances diagnostic AUC by effectively integrating DECT's spectral-spatial data and mitigating class ambiguity, offering a promising tool for noninvasive metastatic burden assessment in clinical practice.

Hunyuan-TurboS: Advancing Large Language Models through Mamba-Transformer Synergy and Adaptive Chain-of-Thought

As Large Language Models (LLMs) rapidly advance, we introduce Hunyuan-TurboS, a novel large hybrid Transformer-Mamba Mixture of Experts (MoE) model. It synergistically combines Mamba's long-sequence processing efficiency with Transformer's superior contextual understanding. Hunyuan-TurboS features an adaptive long-short chain-of-thought (CoT) mechanism, dynamically switching between rapid responses for simple queries and deep "thinking" modes for complex problems, optimizing computational resources. Architecturally, this 56B activated (560B total) parameter model employs 128 layers (Mamba2, Attention, FFN) with an innovative AMF/MF block pattern. Faster Mamba2 ensures linear complexity, Grouped-Query Attention minimizes KV cache, and FFNs use an MoE structure. Pre-trained on 16T high-quality tokens, it supports a 256K context length and is the first industry-deployed large-scale Mamba model. Our comprehensive post-training strategy enhances capabilities via Supervised Fine-Tuning (3M instructions), a novel Adaptive Long-short CoT Fusion method, Multi-round Deliberation Learning for iterative improvement, and a two-stage Large-scale Reinforcement Learning process targeting STEM and general instruction-following. Evaluations show strong performance: overall top 7 rank on LMSYS Chatbot Arena with a score of 1356, outperforming leading models like Gemini-2.0-Flash-001 (1352) and o4-mini-2025-04-16 (1345). TurboS also achieves an average of 77.9% across 23 automated benchmarks. Hunyuan-TurboS balances high performance and efficiency, offering substantial capabilities at lower inference costs than many reasoning models, establishing a new paradigm for efficient large-scale pre-trained models.

Tokenization Constraints in LLMs: A Study of Symbolic and Arithmetic Reasoning Limits

Tokenization is the first - and often underappreciated - layer of computation in language models. While Chain-of-Thought (CoT) prompting enables transformer models to approximate recurrent computation by externalizing intermediate steps, we show that the success of such reasoning is fundamentally bounded by the structure of tokenized inputs. This work presents a theoretical and empirical investigation into how tokenization schemes, particularly subword-based methods like byte-pair encoding (BPE), impede symbolic computation by merging or obscuring atomic reasoning units. We introduce the notion of Token Awareness to formalize how poor token granularity disrupts logical alignment and prevents models from generalizing symbolic procedures. Through systematic evaluation on arithmetic and symbolic tasks, we demonstrate that token structure dramatically affect reasoning performance, causing failure even with CoT, while atomically-aligned formats unlock strong generalization, allowing small models (e.g., GPT-4o-mini) to outperform larger systems (e.g., o1) in structured reasoning. Our findings reveal that symbolic reasoning ability in LLMs is not purely architectural, but deeply conditioned on token-level representations.

Lay-Your-Scene: Natural Scene Layout Generation with Diffusion Transformers

We present Lay-Your-Scene (shorthand LayouSyn), a novel text-to-layout generation pipeline for natural scenes. Prior scene layout generation methods are either closed-vocabulary or use proprietary large language models for open-vocabulary generation, limiting their modeling capabilities and broader applicability in controllable image generation. In this work, we propose to use lightweight open-source language models to obtain scene elements from text prompts and a novel aspect-aware diffusion Transformer architecture trained in an open-vocabulary manner for conditional layout generation. Extensive experiments demonstrate that LayouSyn outperforms existing methods and achieves state-of-the-art performance on challenging spatial and numerical reasoning benchmarks. Additionally, we present two applications of LayouSyn. First, we show that coarse initialization from large language models can be seamlessly combined with our method to achieve better results. Second, we present a pipeline for adding objects to images, demonstrating the potential of LayouSyn in image editing applications.

DexCtrl: Towards Sim-to-Real Dexterity with Adaptive Controller Learning

Dexterous manipulation has seen remarkable progress in recent years, with policies capable of executing many complex and contact-rich tasks in simulation. However, transferring these policies from simulation to real world remains a significant challenge. One important issue is the mismatch in low-level controller dynamics, where identical trajectories can lead to vastly different contact forces and behaviors when control parameters vary. Existing approaches often rely on manual tuning or controller randomization, which can be labor-intensive, task-specific, and introduce significant training difficulty. In this work, we propose a framework that jointly learns actions and controller parameters based on the historical information of both trajectory and controller. This adaptive controller adjustment mechanism allows the policy to automatically tune control parameters during execution, thereby mitigating the sim-to-real gap without extensive manual tuning or excessive randomization. Moreover, by explicitly providing controller parameters as part of the observation, our approach facilitates better reasoning over force interactions and improves robustness in real-world scenarios. Experimental results demonstrate that our method achieves improved transfer performance across a variety of dexterous tasks involving variable force conditions.