Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Abstract:Representation Autoencoders (RAEs) leverage frozen vision foundation models (VFMs) as tokenizer encoders, providing robust high-level representations that facilitate fast convergence and high-quality generation in latent diffusion models. However, freezing the VFM inherently constrains its spatial reconstruction capacity, limiting fine-grained generation and image editing; in contrast, incorporating reconstruction-oriented signals via fine-tuning disrupts the pretrained semantic space and degrades generative fidelity. To address this trade-off, we propose DecQ, a simple yet effective framework for RAEs. Specifically, DecQ introduces lightweight detail-condensing queries that extract fine-grained information from intermediate VFM features through condenser modules. These queries are incorporated into the decoder to support reconstruction and are jointly generated with patch tokens during generative modeling. By aggregating information from both shallow and deep layers, DecQ effectively mitigates the reconstruction--generation trade-off, improving both reconstruction quality and generative performance. Our experiments demonstrate that: (1) with only 8 additional queries and 3.9% extra computation, DecQ improves reconstruction over the frozen DINOv2-based RAE, increasing PSNR from 19.13 dB to 22.76 dB; and (2) for generative modeling, DecQ achieves 3.3$\times$ faster convergence than RAE, attaining an FID of 1.41 without guidance and 1.05 with guidance.
Abstract:In vision-and-language navigation (VLN), self-improvement from policy-induced experience, using only standard VLN action supervision, critically depends on balancing behavioral diversity and learning stability, which governs whether the agent can extract a reliable learning signal for improvement. Increasing behavioral diversity is necessary to expose alternative action hypotheses but can destabilize policy-induced learning signals, whereas overly conservative stability constraints suppress exploration and induce early commitment, making reliable self-improvement difficult. To address this challenge, we propose Stability-Diversity Balance (SDB), a plug-and-play mechanism for balanced self-improvement in VLN. SDB expands each decision step into multiple latent behavioral hypotheses by applying controlled shifts in the instruction-conditioned hidden states, and then performs reliability-aware soft evaluation and aggregation to retain diverse yet instruction-consistent alternatives during learning. An explicit regularizer further constrains hypothesis interactions, preventing excessive drift or premature collapse of hypothesis diversity and stabilizing self-improvement without discarding training signals. Experiments on R2R, SOON, and REVERIE show consistent improvements; for example, on REVERIE val-unseen, SDB improves SPL from 33.73 to 35.93 and OSR from 51.07 to 54.25.
Abstract:Vision-and-Language Navigation requires agents to follow natural-language instructions in visually changing environments. A central challenge is the dynamic entanglement between language and observations: the meaning of instruction shifts as the agent's field of view and spatial context evolve. However, many existing models encode the instruction as a static global representation, limiting their ability to adapt instruction meaning to the current visual context. We therefore model instruction understanding as an Instruction-as-State variable: a decision-relevant, token-level instruction state that evolves step by step conditioned on the agent's perceptual state, where the perceptual state denotes the observation-grounded navigation context at each step. To realize this principle, we introduce State-Entangled Environment-Guided Instruction Understanding (S-EGIU), a coarse-to-fine framework for state-conditioned segment activation and token-level semantic refinement. At the coarse level, S-EGIU activates the instruction segment whose semantics align with the current observation. At the fine level, it refines the activated segment through observation-guided token grounding and contextual modeling, sharpening its internal semantics under the current observation. Together, these stages maintain an instruction state that is continuously updated according to the agent's perceptual state during navigation. S-EGIU delivers strong performance on several key metrics, including a +2.68% SPL gain on REVERIE Test Unseen, and demonstrates consistent efficiency gains across multiple VLN benchmarks, underscoring the value of dynamic instruction--perception entanglement.
Abstract:The widespread adoption of CT has notably increased the number of detected lung nodules. However, current deep learning methods for classifying benign and malignant nodules often fail to comprehensively integrate global and local features, and most of them have not been validated through clinical trials. To address this, we developed DeepFAN, a transformer-based model trained on over 10K pathology-confirmed nodules and further conducted a multi-reader, multi-case clinical trial to evaluate its efficacy in assisting junior radiologists. DeepFAN achieved diagnostic area under the curve (AUC) of 0.939 (95% CI 0.930-0.948) on an internal test set and 0.954 (95% CI 0.934-0.973) on the clinical trial dataset involving 400 cases across three independent medical institutions. Explainability analysis indicated higher contributions from global than local features. Twelve readers' average performance significantly improved by 10.9% (95% CI 8.3%-13.5%) in AUC, 10.0% (95% CI 8.9%-11.1%) in accuracy, 7.6% (95% CI 6.1%-9.2%) in sensitivity, and 12.6% (95% CI 10.9%-14.3%) in specificity (P<0.001 for all). Nodule-level inter-reader diagnostic consistency improved from fair to moderate (overall k: 0.313 vs. 0.421; P=0.019). In conclusion, DeepFAN effectively assisted junior radiologists and may help homogenize diagnostic quality and reduce unnecessary follow-up of indeterminate pulmonary nodules. Chinese Clinical Trial Registry: ChiCTR2400084624.
Abstract:To characterize lobar and segmental airway volume differences between systemic lupus erythematosus (SLE) patients with interstitial lung disease (ILD) and those without ILD (non-ILD) using a deep learning-based approach on non-contrast chest high-resolution CT (HRCT). Methods: A retrospective analysis was conducted on 106 SLE patients (27 SLE-ILD, 79 SLE-non-ILD) who underwent HRCT. A customized deep learning framework based on the U-Net architecture was developed to automatically segment airway structures at the lobar and segmental levels via HRCT. Volumetric measurements of lung lobes and segments derived from the segmentations were statistically compared between the two groups using two-sample t-tests (significance threshold: p < 0.05). Results: At lobar level, significant airway volume enlargement in SLE-ILD patients was observed in the right upper lobe (p=0.009) and left upper lobe (p=0.039) compared to SLE-non-ILD. At the segmental level, significant differences were found in segments including R1 (p=0.016), R3 (p<0.001), and L3 (p=0.038), with the most marked changes in the upper lung zones, while lower zones showed non-significant trends. Conclusion: Our study demonstrates that an automated deep learning-based approach can effectively quantify airway volumes on HRCT scans and reveal significant, region-specific airway dilation in patients with SLE-ILD compared to those without ILD. The pattern of involvement, predominantly affecting the upper lobes and specific segments, highlights a distinct topographic phenotype of SLE-ILD and implicates airway structural alterations as a potential biomarker for disease presence. This AI-powered quantitative imaging biomarker holds promise for enhancing the early detection and monitoring of ILD in the SLE population, ultimately contributing to more personalized patient management.
Abstract:Agent skills, structured procedural knowledge packages injected at inference time, are increasingly used to augment LLM agents on software engineering tasks. However, their real utility in end-to-end development settings remains unclear. We present SWE-Skills-Bench, the first requirement-driven benchmark that isolates the marginal utility of agent skills in real-world software engineering (SWE). It pairs 49 public SWE skills with authentic GitHub repositories pinned at fixed commits and requirement documents with explicit acceptance criteria, yielding approximately 565 task instances across six SWE subdomains. We introduce a deterministic verification framework that maps each task's acceptance criteria to execution-based tests, enabling controlled paired evaluation with and without the skill. Our results show that skill injection benefits are far more limited than rapid adoption suggests: 39 of 49 skills yield zero pass-rate improvement, and the average gain is only +1.2%. Token overhead varies from modest savings to a 451% increase while pass rates remain unchanged. Only seven specialized skills produce meaningful gains (up to +30%), while three degrade performance (up to -10%) due to version-mismatched guidance conflicting with project context. These findings suggest that agent skills are a narrow intervention whose utility depends strongly on domain fit, abstraction level, and contextual compatibility. SWE-Skills-Bench provides a testbed for evaluating the design, selection, and deployment of skills in software engineering agents. SWE-Skills-Bench is available at https://github.com/GeniusHTX/SWE-Skills-Bench.
Abstract:Humanoid robots deployed in real-world scenarios often need to carry unknown payloads, which introduce significant mismatch and degrade the effectiveness of simulation-to-reality reinforcement learning methods. To address this challenge, we propose a two-stage gradient-based system identification framework built on the differentiable simulator MuJoCo XLA. The first stage calibrates the nominal robot model using real-world data to reduce intrinsic sim-to-real discrepancies, while the second stage further identifies the mass distribution of the unknown payload. By explicitly reducing structured model bias prior to policy training, our approach enables zero-shot transfer of reinforcement learning policies to hardware under heavy-load conditions. Extensive simulation and real-world experiments demonstrate more precise parameter identification, improved motion tracking accuracy, and substantially enhanced agility and robustness compared to existing baselines. Project Page: https://mwondering.github.io/halo-humanoid/
Abstract:Temporal knowledge graphs (TKGs) support reasoning over time-evolving facts, yet state-of-the-art models are often computationally heavy and costly to deploy. Existing compression and distillation techniques are largely designed for static graphs; directly applying them to temporal settings may overlook time-dependent interactions and lead to performance degradation. We propose an LLM-assisted distillation framework specifically designed for temporal knowledge graph reasoning. Beyond a conventional high-capacity temporal teacher, we incorporate a large language model as an auxiliary instructor to provide enriched supervision. The LLM supplies broad background knowledge and temporally informed signals, enabling a lightweight student to better model event dynamics without increasing inference-time complexity. Training is conducted by jointly optimizing supervised and distillation objectives, using a staged alignment strategy to progressively integrate guidance from both teachers. Extensive experiments on multiple public TKG benchmarks with diverse backbone architectures demonstrate that the proposed approach consistently improves link prediction performance over strong distillation baselines, while maintaining a compact and efficient student model. The results highlight the potential of large language models as effective teachers for transferring temporal reasoning capability to resource-efficient TKG systems.
Abstract:Current unified multimodal models for image generation and editing typically rely on massive parameter scales (e.g., >10B), entailing prohibitive training costs and deployment footprints. In this work, we present DeepGen 1.0, a lightweight 5B unified model that achieves comprehensive capabilities competitive with or surpassing much larger counterparts. To overcome the limitations of compact models in semantic understanding and fine-grained control, we introduce Stacked Channel Bridging (SCB), a deep alignment framework that extracts hierarchical features from multiple VLM layers and fuses them with learnable 'think tokens' to provide the generative backbone with structured, reasoning-rich guidance. We further design a data-centric training strategy spanning three progressive stages: (1) Alignment Pre-training on large-scale image-text pairs and editing triplets to synchronize VLM and DiT representations, (2) Joint Supervised Fine-tuning on a high-quality mixture of generation, editing, and reasoning tasks to foster omni-capabilities, and (3) Reinforcement Learning with MR-GRPO, which leverages a mixture of reward functions and supervision signals, resulting in substantial gains in generation quality and alignment with human preferences, while maintaining stable training progress and avoiding visual artifacts. Despite being trained on only ~50M samples, DeepGen 1.0 achieves leading performance across diverse benchmarks, surpassing the 80B HunyuanImage by 28% on WISE and the 27B Qwen-Image-Edit by 37% on UniREditBench. By open-sourcing our training code, weights, and datasets, we provide an efficient, high-performance alternative to democratize unified multimodal research.
Abstract:Video Large Language Models (VideoLLMs) have recently achieved strong performance in video understanding tasks. However, we identify a previously underexplored generation failure: severe output repetition, where models degenerate into self-reinforcing loops of repeated phrases or sentences. This failure mode is not captured by existing VideoLLM benchmarks, which focus primarily on task accuracy and factual correctness. We introduce VideoSTF, the first framework for systematically measuring and stress-testing output repetition in VideoLLMs. VideoSTF formalizes repetition using three complementary n-gram-based metrics and provides a standardized testbed of 10,000 diverse videos together with a library of controlled temporal transformations. Using VideoSTF, we conduct pervasive testing, temporal stress testing, and adversarial exploitation across 10 advanced VideoLLMs. We find that output repetition is widespread and, critically, highly sensitive to temporal perturbations of video inputs. Moreover, we show that simple temporal transformations can efficiently induce repetitive degeneration in a black-box setting, exposing output repetition as an exploitable security vulnerability. Our results reveal output repetition as a fundamental stability issue in modern VideoLLMs and motivate stability-aware evaluation for video-language systems. Our evaluation code and scripts are available at: https://github.com/yuxincao22/VideoSTF_benchmark.