Deep Computational Model for the Inference of Ventricular Activation Properties

Patient-specific cardiac computational models are essential for the efficient realization of precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can provide non-invasive characterizations of cardiac functions for individual patients, and therefore are promising for the patient-specific diagnosis and therapy stratification. However, current workflows for both the anatomical and functional twinning phases, referring to the inference of model anatomy and parameter from clinical data, are not sufficiently efficient, robust, and accurate. In this work, we propose a deep learning based patient-specific computational model, which can fuse both anatomical and electrophysiological information for the inference of ventricular activation properties, i.e., conduction velocities and root nodes. The activation properties can provide a quantitative assessment of cardiac electrophysiological function for the guidance of interventional procedures. We employ the Eikonal model to generate simulated electrocardiogram (ECG) with ground truth properties to train the inference model, where specific patient information has also been considered. For evaluation, we test the model on the simulated data and obtain generally promising results with fast computational time.

Distributional Correlation--Aware Knowledge Distillation for Stock Trading Volume Prediction

Traditional knowledge distillation in classification problems transfers the knowledge via class correlations in the soft label produced by teacher models, which are not available in regression problems like stock trading volume prediction. To remedy this, we present a novel distillation framework for training a light-weight student model to perform trading volume prediction given historical transaction data. Specifically, we turn the regression model into a probabilistic forecasting model, by training models to predict a Gaussian distribution to which the trading volume belongs. The student model can thus learn from the teacher at a more informative distributional level, by matching its predicted distributions to that of the teacher. Two correlational distillation objectives are further introduced to encourage the student to produce consistent pair-wise relationships with the teacher model. We evaluate the framework on a real-world stock volume dataset with two different time window settings. Experiments demonstrate that our framework is superior to strong baseline models, compressing the model size by $5\times$ while maintaining $99.6\%$ prediction accuracy. The extensive analysis further reveals that our framework is more effective than vanilla distillation methods under low-resource scenarios.

A sharp uniform-in-time error estimate for Stochastic Gradient Langevin Dynamics

We establish a sharp uniform-in-time error estimate for the Stochastic Gradient Langevin Dynamics (SGLD), which is a popular sampling algorithm. Under mild assumptions, we obtain a uniform-in-time $O(\eta^2)$ bound for the KL-divergence between the SGLD iteration and the Langevin diffusion, where $\eta$ is the step size (or learning rate). Our analysis is also valid for varying step sizes. Based on this, we are able to obtain an $O(\eta)$ bound for the distance between the SGLD iteration and the invariant distribution of the Langevin diffusion, in terms of Wasserstein or total variation distances.

On uniform-in-time diffusion approximation for stochastic gradient descent

The diffusion approximation of stochastic gradient descent (SGD) in current literature is only valid on a finite time interval. In this paper, we establish the uniform-in-time diffusion approximation of SGD, by only assuming that the expected loss is strongly convex and some other mild conditions, without assuming the convexity of each random loss function. The main technique is to establish the exponential decay rates of the derivatives of the solution to the backward Kolmogorov equation. The uniform-in-time approximation allows us to study asymptotic behaviors of SGD via the continuous stochastic differential equation (SDE) even when the random objective function $f(\cdot;\xi)$ is not strongly convex.

On the Impact of Noises in Crowd-Sourced Data for Speech Translation

Training speech translation (ST) models requires large and high-quality datasets. MuST-C is one of the most widely used ST benchmark datasets. It contains around 400 hours of speech-transcript-translation data for each of the eight translation directions. This dataset passes several quality-control filters during creation. However, we find that MuST-C still suffers from three major quality issues: audio-text misalignment, inaccurate translation, and unnecessary speaker's name. What are the impacts of these data quality issues for model development and evaluation? In this paper, we propose an automatic method to fix or filter the above quality issues, using English-German (En-De) translation as an example. Our experiments show that ST models perform better on clean test sets, and the rank of proposed models remains consistent across different test sets. Besides, simply removing misaligned data points from the training set does not lead to a better ST model.

CSI Sensing from Heterogeneous User Feedbacks: A Constrained Phase Retrieval Approach

This paper investigates the downlink channel state information (CSI) sensing in 5G heterogeneous networks composed of user equipments (UEs) with different feedback capabilities. We aim to enhance the CSI accuracy of UEs only affording the low-resolution Type-I codebook. While existing works have demonstrated that the task can be accomplished by solving a phase retrieval (PR) formulation based on the feedback of precoding matrix indicator (PMI) and channel quality indicator (CQI), they need many feedback rounds. In this paper, we propose a novel CSI sensing scheme that can significantly reduce the feedback overhead. Our scheme involves a novel parameter dimension reduction design by exploiting the spatial consistency of wireless channels among nearby UEs, and a constrained PR (CPR) formulation that characterizes the feasible region of CSI by the PMI information. To address the computational challenge due to the non-convexity and the large number of constraints of CPR, we develop a two-stage algorithm that firstly identifies and removes inactive constraints, followed by a fast first-order algorithm. The study is further extended to multi-carrier systems. Extensive tests over DeepMIMO and QuaDriGa datasets showcase that our designs greatly outperform existing methods and achieve the high-resolution Type-II codebook performance with a few rounds of feedback.

On the Learning of Non-Autoregressive Transformers

Non-autoregressive Transformer (NAT) is a family of text generation models, which aims to reduce the decoding latency by predicting the whole sentences in parallel. However, such latency reduction sacrifices the ability to capture left-to-right dependencies, thereby making NAT learning very challenging. In this paper, we present theoretical and empirical analyses to reveal the challenges of NAT learning and propose a unified perspective to understand existing successes. First, we show that simply training NAT by maximizing the likelihood can lead to an approximation of marginal distributions but drops all dependencies between tokens, where the dropped information can be measured by the dataset's conditional total correlation. Second, we formalize many previous objectives in a unified framework and show that their success can be concluded as maximizing the likelihood on a proxy distribution, leading to a reduced information loss. Empirical studies show that our perspective can explain the phenomena in NAT learning and guide the design of new training methods.

Decoupling Predictions in Distributed Learning for Multi-Center Left Atrial MRI Segmentation

Distributed learning has shown great potential in medical image analysis. It allows to use multi-center training data with privacy protection. However, data distributions in local centers can vary from each other due to different imaging vendors, and annotation protocols. Such variation degrades the performance of learning-based methods. To mitigate the influence, two groups of methods have been proposed for different aims, i.e., the global methods and the personalized methods. The former are aimed to improve the performance of a single global model for all test data from unseen centers (known as generic data); while the latter target multiple models for each center (denoted as local data). However, little has been researched to achieve both goals simultaneously. In this work, we propose a new framework of distributed learning that bridges the gap between two groups, and improves the performance for both generic and local data. Specifically, our method decouples the predictions for generic data and local data, via distribution-conditioned adaptation matrices. Results on multi-center left atrial (LA) MRI segmentation showed that our method demonstrated superior performance over existing methods on both generic and local data. Our code is available at https://github.com/key1589745/decouple_predict

Rethinking the Openness of CLIP

Contrastive Language-Image Pre-training (CLIP) has demonstrated great potential in realizing open-vocabulary image classification in a matching style, because of its holistic use of natural language supervision that covers unconstrained real-world visual concepts. However, it is, in turn, also difficult to evaluate and analyze the openness of CLIP-like models, since they are in theory open to any vocabulary but the actual accuracy varies. To address the insufficiency of conventional studies on openness, we resort to an incremental view and define the extensibility, which essentially approximates the model's ability to deal with new visual concepts, by evaluating openness through vocabulary expansions. Our evaluation based on extensibility shows that CLIP-like models are hardly truly open and their performances degrade as the vocabulary expands to different degrees. Further analysis reveals that the over-estimation of openness is not because CLIP-like models fail to capture the general similarity of image and text features of novel visual concepts, but because of the confusion among competing text features, that is, they are not stable with respect to the vocabulary. In light of this, we propose to improve the openness of CLIP from the perspective of feature space by enforcing the distinguishability of text features. Our method retrieves relevant texts from the pre-training corpus to enhance prompts for inference, which boosts the extensibility and stability of CLIP even without fine-tuning.

Decoupling Knowledge from Memorization: Retrieval-augmented Prompt Learning

Prompt learning approaches have made waves in natural language processing by inducing better few-shot performance while they still follow a parametric-based learning paradigm; the oblivion and rote memorization problems in learning may encounter unstable generalization issues. Specifically, vanilla prompt learning may struggle to utilize atypical instances by rote during fully-supervised training or overfit shallow patterns with low-shot data. To alleviate such limitations, we develop RetroPrompt with the motivation of decoupling knowledge from memorization to help the model strike a balance between generalization and memorization. In contrast with vanilla prompt learning, RetroPrompt constructs an open-book knowledge-store from training instances and implements a retrieval mechanism during the process of input, training and inference, thus equipping the model with the ability to retrieve related contexts from the training corpus as cues for enhancement. Extensive experiments demonstrate that RetroPrompt can obtain better performance in both few-shot and zero-shot settings. Besides, we further illustrate that our proposed RetroPrompt can yield better generalization abilities with new datasets. Detailed analysis of memorization indeed reveals RetroPrompt can reduce the reliance of language models on memorization; thus, improving generalization for downstream tasks.