DriftST: One-Step Generative Inference of Spatial Transcriptomics from H\&E Histology

Spatial Transcriptomics (ST) measures gene expression while preserving spatial context, but its high cost and low throughput leave public datasets small. Inferring expression directly from widely available Hematoxylin and Eosin (H&E) stained histology offers a cost-effective alternative. However, existing approaches face several limitations: regression methods over-smooth toward the conditional mean, while generative methods are faithful but require slow multi-step inference; most methods treat genes as independent and equally important, ignoring inter-gene dependencies and heterogeneous gene informativeness; and most are tailored to a single resolution, either spot-level or cell-level. To address these issues, we propose DriftST, a unified framework for inferring spatially resolved gene expression from H&E images. DriftST builds on a Cellular Drifting generative model that learns a direct drift from a histology-conditioned source to the expression distribution, retaining generative expressiveness while enabling efficient one-step generation. To capture gene structure, we introduce the STransformer, which combines a co-expression attention module for inter-gene dependencies with a gene residual gate for differential gene importance. Operating on a generic gene-panel representation, DriftST applies directly to both spot-level and cell-level data in one framework, and extensive experiments across diverse tissues and platforms show that it achieves state-of-the-art performance at both resolutions.

Argus: Metric Panoramic 3D Reconstruction for Indoor Scenes

Metric feed-forward 3D reconstruction for panoramic data remains under-explored due to the lack of large-scale panoramic RGB-D training data. We present Realsee3D, a hybrid dataset of 10K indoor scenes (1K real, 9K synthetic) with 299K panoramic viewpoints and precise metric annotations, and Argus, a feed-forward network trained on it for metric panoramic 3D reconstruction. In the sparse unordered capture setting of Realsee3D, a poorly chosen coordinate anchor can cause global pose drift. Argus addresses this with a learned covisibility module that selects the geometrically optimal reference view to anchor the metric world frame. To further improve multi-task learning, we decompose the bidirectional pixel-to-world mapping into interpretable sub-steps with per-step supervision and cross-coordinate joint constraints, reinforcing geometric consistency across prediction branches. On the Realsee3D benchmark, Argus achieves state-of-the-art metric performance in camera pose estimation, depth estimation, and point cloud reconstruction. Project page: https://argus-paper.realsee.ai.

Escaping the Self-Confirmation Trap: An Execute-Distill-Verify Paradigm for Agentic Experience Learning

Experience-driven self-evolution is critical for large language model (LLM) agents to improve through open-world interaction. However, existing experience learning methods mostly rely on single-agent loops, where the same agent executes tasks, summarizes outcomes, and determines memory content. This setup makes agents vulnerable to the Self-Confirmation Trap: wrong-but-self-consistent trajectories are misidentified as successful experience, leading to cumulative errors during retrieval and reuse. To address this issue, we propose EDV, an Execute-Distill-Verify framework for reliable experience learning. In the Execute stage, multiple heterogeneous agents explore the same task space in parallel to generate diverse candidate trajectories. In the Distill stage, a dedicated third-party agent comparatively analyzes these trajectories to produce candidate experiences, reducing executor-centric summarization bias. In the Verify stage, the execution group validates candidates via a consensus mechanism, and only approved experiences are written into shared or private memory. By decoupling the three stages, EDV transforms experience learning from isolated self-reflection into collaborative construction, filtering erroneous and noisy content before memory insertion. We evaluate EDV on three challenging long-horizon benchmarks: tau2-bench, Mind2Web and MMTB. Results show EDV consistently outperforms strong baselines, validating that reliable experience construction is essential for robust agent self-evolution. Our code is available at https://github.com/shidingz/EDV.

One Layer's Trash is Another Layer's Treasure: Adaptive Layer-wise Visual Token Selection in LVLMs

Large Vision-Language Models (LVLMs) have achieved remarkable success across diverse multimodal tasks, yet their practical deployment remains constrained by the computational burden arising from lengthy visual tokens. While visual token pruning has emerged as a promising solution, existing methods suffer from a fundamental limitation: once tokens are pruned at a specific layer, they become inaccessible to all subsequent layers, leading to premature information loss that can compromise model performance. Through empirical studies, we observe that different layers exhibit distinct visual region focus, indicating a varying optimal token subset across layers. Motivated by this insight, we propose Adaptive Layer-wise Visual Token Selection (ALVTS), a novel framework that breaks away from the conventional static token pruning paradigm. ALVTS incorporates a lightweight token selector to identify and route important tokens for further processing, while allowing less important tokens to skip the layer, thus minimizing computational redundancy. These two streams of tokens are seamlessly reintegrated before being fed into subsequent layers, facilitating adaptive compression across the entire model. Grounded in our importance consistency constrained low-rank approximation, the proposed token selection module closely emulates the full attention mechanism, effectively capturing its essential patterns without requiring model retraining. Extensive experiments on LLaVA-1.5, LLaVA-NeXT, and Qwen2.5-VL validate the effectiveness of our method. With an 89% token compression ratio, ALVTS retains 96.7% of the original model's accuracy, achieving a superior efficiency-accuracy trade-off for LVLM inference.

SaliMory: Orchestrating Cognitive Memory for Conversational Agents

Conversational agents that serve as lifelong companions must maintain persistent memory across all interactions. However, simply expanding context windows with raw retrieval degrades reasoning quality, while training memory agents via standard reinforcement learning creates a severe credit assignment bottleneck in a multi-stage pipeline. To solve this, we introduce SALIMORY, a framework that trains a single language model to manage a cognitively-structured memory-spanning user facts, preferences, and working memory. By introducing a hierarchical stage-wise process reward and reward-decomposed contrastive refinement, SALIMORY provides isolated supervision for distinct memory operations (selective filtering, consolidation, and cue-driven recall) end-to-end. SALIMORY cuts memory-attributed failures by one-third, outperforms the state-of-the-art by over 10% in end-to-end accuracy, and more than doubles the Good Personalization rate.

When Attention Collapses: Stage-Aware Visual Token Pruning from Structure to Semantics

Vision-Language Models (VLMs) have demonstrated remarkable capabilities but suffer from significant computational overhead during inference. While visual token pruning offers a promising solution, existing methods predominantly rely on initial attention scores. This single-metric paradigm presents a critical flaw: high attention scores inherently collapse onto semantically similar regions, thereby severely reducing feature diversity and discarding vital contextual details. To address this, we introduce Structure-to-Semantics (STS), a novel two-stage visual token pruning framework that explicitly decouples the pruning process. The first stage employs a repulsion-based sampling mechanism to maximize spatial and structural diversity. The second stage leverages instruction-aware cross-attention to precisely filter out prompt-irrelevant tokens. This two-stage synergy constitutes the core of STS, first ensuring geometric coverage and then refining the retained tokens according to semantic relevance. Extensive evaluations demonstrate that STS mitigates the redundancy caused by attention-based selection, improving both structural diversity and fine-grained task alignment of the preserved visual tokens.

From Fact Overwriting to Knowledge Evolution: Causal Editing via On-Policy Self-Distillation

While Knowledge Editing (KE) enables efficient updates, its dominant Static Fact Overwriting paradigm treats LLMs as discrete databases, forcibly injecting isolated facts. Fracturing pre-trained logical topologies, this triggers Epistemic Dissonance -- a pathology where un-evolved legacy priors force the model to explicitly negate the injected update. Idealized interventions reveal that this is an inherent structural flaw rather than mere algorithmic noise, with a zero-distortion proxy yielding a catastrophic 95.6% self-refutation rate. Given the causally driven nature of real-world knowledge, grounding updates in explicit causal narratives effectively collapses this conflict rate to just 6.6%, underscoring the imperative for a paradigm shift toward Causal Editing. To internalize this evolution, we propose CODE (Causal On-policy Distillation for Editing). By coupling causal bootstrapping with asymmetric on-policy distillation, CODE engraves causal transition logic directly into parametric memory. Experiments on LLaMA-3.1 and Qwen-2.5 show CODE drastically suppresses self-refutation to 1.8% while securing robust multi-hop accuracy (up to 83.5%), seamlessly transforming discrete fact injection into coherent knowledge evolution. Code is available at https://github.com/CrashBugger/CODE.

QUEST: Training Frontier Deep Research Agents with Fully Synthetic Tasks

Deep research agents extend the role of search engines from retrieving keyword-matched pages to synthesizing knowledge, fundamentally changing how humans interact with information. However, frontier systems remain proprietary, while existing open agents often generalize poorly across different task types, leaving unclear how to train a broadly capable deep research agent. We release QUEST, a family of open models (ranging from 2B to 35B) that serve as general-purpose deep research agents designed to handle a wide range of long-horizon search tasks, with strong capabilities in fact seeking, citation grounding, and report synthesis. To build QUEST, we propose an effective training recipe combining mid-training, supervised fine-tuning, and reinforcement learning. Central to this recipe is a curated data synthesis pipeline based on unified rubric trees, which applies to different task types and enables synthesizing training data with verifiable rewards without human annotation. In addition, QUEST incorporates a built-in context management mechanism that enables effective long-horizon reasoning and knowledge synthesis. Using only 8K synthesized tasks, QUEST approaches or even surpasses frontier closed-source agents across eight deep research benchmarks spanning diverse task types, and achieves the best overall performance among recent open-weight agents. We released everything: models, data, and training scripts.

SWE-Mutation: Can LLMs Generate Reliable Test Suites in Software Engineering?

Evaluating software engineering capabilities has become a core component of modern large language models (LLMs); however, the key bottleneck hindering further scaling lies not in the scarcity of high-quality solutions, but in the lack of high-quality test suites. Test suites are indispensable both for synthesizing program repair trajectories and for providing precise feedback signals in reinforcement learning. Unfortunately, due to the high cost and difficulty of annotation, high-quality test suites have long been hard to obtain, while those automatically generated by LLMs tend to be superficial and lack sufficient discriminative power. As a first step toward constructing high-quality test suites, we introduce SWE-Mutation, a benchmark for evaluating LLM-generated test suites. The benchmark characterizes test suites by introducing systematically mutated solutions that attempt to ``fool'' the test suites and pass validation. We further propose an agentic, language-agnostic framework for automatically generating complex mutants. Our benchmark consists of 2,636 mutated variants derived from 800 original instances and includes a multilingual subset spanning nine programming languages. Experiments on seven LLMs reveal that even DeepSeek-V3.1 achieves only 10.20% verification and 36.15% detection rates, highlighting the inadequacy of current LLMs. Additionally, our agentic mutation strategy enhances realism, reducing average detection rates from 71.04% to 39.81% compared to conventional methods. These findings expose persistent deficiencies in the ability of current LLMs to generate reliable and discriminative test suites.

Dual-Integrated Low-Latency Single-Lens Infrared Computational Imaging for Object Detection

Computational imaging enables compact infrared systems, but deep-learning pipelines that combine image reconstruction and object detection often introduce substantial inference latency. Most existing acceleration strategies compress the reconstruction network while overlooking physical priors from the optical path, leaving a trade-off between accuracy and speed. We present Physics-aware Dual-Integrated Network (PDI-Net), a low-latency framework that integrates infrared reconstruction with object detection and further embeds optical priors into the learning process. PDI-Net uses a supervised U-Net during training, while a semi-U-Net encoder shares features directly with a YOLO-based detector during inference, avoiding full image reconstruction. To bridge the gap between fidelity-oriented reconstruction features and detection-oriented semantics, we introduce a physics-aware large-small bridge (PALS-Bridge), which uses field-dependent point spread function priors to adaptively modulate multiscale convolutional branches. A physics-informed optical degradation simulation pipeline is also developed for training and validation. The method is deployed on a single-lens infrared camera, reducing system weight by about 50% compared with traditional multi-lens designs. On the M3FD benchmark under low-SNR conditions, PDI-Net reduces inference time by 84.06% compared with the Rec+Det with pruning strategy while improving mAP@0.5:0.95 by 5.07%. These results demonstrate compact, low-latency computational infrared imaging for real-time object detection on resource-constrained platforms.