Soochow University
Abstract:We present UniRef-Image-Edit, a high-performance multi-modal generation system that unifies single-image editing and multi-image composition within a single framework. Existing diffusion-based editing methods often struggle to maintain consistency across multiple conditions due to limited interaction between reference inputs. To address this, we introduce Sequence-Extended Latent Fusion (SELF), a unified input representation that dynamically serializes multiple reference images into a coherent latent sequence. During a dedicated training stage, all reference images are jointly constrained to fit within a fixed-length sequence under a global pixel-budget constraint. Building upon SELF, we propose a two-stage training framework comprising supervised fine-tuning (SFT) and reinforcement learning (RL). In the SFT stage, we jointly train on single-image editing and multi-image composition tasks to establish a robust generative prior. We adopt a progressive sequence length training strategy, in which all input images are initially resized to a total pixel budget of $1024^2$, and are then gradually increased to $1536^2$ and $2048^2$ to improve visual fidelity and cross-reference consistency. This gradual relaxation of compression enables the model to incrementally capture finer visual details while maintaining stable alignment across references. For the RL stage, we introduce Multi-Source GRPO (MSGRPO), to our knowledge the first reinforcement learning framework tailored for multi-reference image generation. MSGRPO optimizes the model to reconcile conflicting visual constraints, significantly enhancing compositional consistency. We will open-source the code, models, training data, and reward data for community research purposes.
Abstract:The Rising Multi-Armed Bandit (RMAB) framework models environments where expected rewards of arms increase with plays, which models practical scenarios where performance of each option improves with the repeated usage, such as in robotics and hyperparameter tuning. For instance, in hyperparameter tuning, the validation accuracy of a model configuration (arm) typically increases with each training epoch. A defining characteristic of RMAB is em horizon-dependent optimality: unlike standard settings, the optimal strategy here shifts dramatically depending on the available budget $T$. This implies that knowledge of $T$ yields significantly greater utility in RMAB, empowering the learner to align its decision-making with this shifting optimality. However, the horizon-aware setting remains underexplored. To address this, we propose a novel CUmulative Reward Estimation UCB (CURE-UCB) that explicitly integrates the horizon. We provide a rigorous analysis establishing a new regret upper bound and prove that our method strictly outperforms horizon-agnostic strategies in structured environments like ``linear-then-flat'' instances. Extensive experiments demonstrate its significant superiority over baselines.
Abstract:While diffusion models have shown exceptional capabilities in aesthetic image synthesis, they often struggle with complex spatial understanding and reasoning. Existing approaches resort to Multimodal Large Language Models (MLLMs) to enhance this capability. However, they either incur high computational costs through joint training or suffer from spatial information loss when relying solely on textual prompts. To alleviate these limitations, we propose a Spatial Chain-of-Thought (SCoT) framework, a plug-and-play approach that effectively bridges the reasoning capabilities of MLLMs with the generative power of diffusion models. Specifically, we first enhance the diffusion model's layout awareness by training it on an interleaved text-coordinate instruction format. We then leverage state-of-the-art MLLMs as planners to generate comprehensive layout plans, transferring their spatial planning capabilities directly to the generation process. Extensive experiments demonstrate that our method achieves state-of-the-art performance on image generation benchmarks and significantly outperforms baselines on complex reasoning tasks, while also showing strong efficacy in image editing scenarios.
Abstract:Causal inference holds immense value in fields such as healthcare, economics, and social sciences. However, traditional causal analysis workflows impose significant technical barriers, requiring researchers to possess dual backgrounds in statistics and computer science, while manually selecting algorithms, handling data quality issues, and interpreting complex results. To address these challenges, we propose CausalAgent, a conversational multi-agent system for end-to-end causal inference. The system innovatively integrates Multi-Agent Systems (MAS), Retrieval-Augmented Generation (RAG), and the Model Context Protocol (MCP) to achieve automation from data cleaning and causal structure learning to bias correction and report generation through natural language interaction. Users need only upload a dataset and pose questions in natural language to receive a rigorous, interactive analysis report. As a novel user-centered human-AI collaboration paradigm, CausalAgent explicitly models the analysis workflow. By leveraging interactive visualizations, it significantly lowers the barrier to entry for causal analysis while ensuring the rigor and interpretability of the process.
Abstract:Graph Domain Adaptation (GDA) transfers knowledge from labeled source graphs to unlabeled target graphs but is challenged by complex, multi-faceted distributional shifts. Existing methods attempt to reduce distributional shifts by aligning manually selected graph elements (e.g., node attributes or structural statistics), which typically require manually designed graph filters to extract relevant features before alignment. However, such approaches are inflexible: they rely on scenario-specific heuristics, and struggle when dominant discrepancies vary across transfer scenarios. To address these limitations, we propose \textbf{ADAlign}, an Adaptive Distribution Alignment framework for GDA. Unlike heuristic methods, ADAlign requires no manual specification of alignment criteria. It automatically identifies the most relevant discrepancies in each transfer and aligns them jointly, capturing the interplay between attributes, structures, and their dependencies. This makes ADAlign flexible, scenario-aware, and robust to diverse and dynamically evolving shifts. To enable this adaptivity, we introduce the Neural Spectral Discrepancy (NSD), a theoretically principled parametric distance that provides a unified view of cross-graph shifts. NSD leverages neural characteristic function in the spectral domain to encode feature-structure dependencies of all orders, while a learnable frequency sampler adaptively emphasizes the most informative spectral components for each task via minimax paradigm. Extensive experiments on 10 datasets and 16 transfer tasks show that ADAlign not only outperforms state-of-the-art baselines but also achieves efficiency gains with lower memory usage and faster training.
Abstract:Graph Domain Adaptation (GDA) aims to bridge distribution shifts between domains by transferring knowledge from well-labeled source graphs to given unlabeled target graphs. One promising recent approach addresses graph transfer by discretizing the adaptation process, typically through the construction of intermediate graphs or stepwise alignment procedures. However, such discrete strategies often fail in real-world scenarios, where graph structures evolve continuously and nonlinearly, making it difficult for fixed-step alignment to approximate the actual transformation process. To address these limitations, we propose \textbf{DiffGDA}, a \textbf{Diff}usion-based \textbf{GDA} method that models the domain adaptation process as a continuous-time generative process. We formulate the evolution from source to target graphs using stochastic differential equations (SDEs), enabling the joint modeling of structural and semantic transitions. To guide this evolution, a domain-aware network is introduced to steer the generative process toward the target domain, encouraging the diffusion trajectory to follow an optimal adaptation path. We theoretically show that the diffusion process converges to the optimal solution bridging the source and target domains in the latent space. Extensive experiments on 14 graph transfer tasks across 8 real-world datasets demonstrate DiffGDA consistently outperforms state-of-the-art baselines.
Abstract:Vision-Language-Action Models (VLAs) have emerged as a key paradigm of Physical AI and are increasingly deployed in autonomous vehicles, robots, and smart spaces. In these resource-constrained on-device settings, selecting an appropriate large language model (LLM) backbone is a critical challenge: models must balance accuracy with strict inference latency and hardware efficiency constraints. This makes hardware-software co-design a game-changing requirement for on-device LLM deployment, where each hardware platform demands a tailored architectural solution. We propose a hardware co-design law that jointly captures model accuracy and inference performance. Specifically, we model training loss as an explicit function of architectural hyperparameters and characterise inference latency via roofline modelling. We empirically evaluate 1,942 candidate architectures on NVIDIA Jetson Orin, training 170 selected models for 10B tokens each to fit a scaling law relating architecture to training loss. By coupling this scaling law with latency modelling, we establish a direct accuracy-latency correspondence and identify the Pareto frontier for hardware co-designed LLMs. We further formulate architecture search as a joint optimisation over precision and performance, deriving feasible design regions under industrial hardware and application budgets. Our approach reduces architecture selection from months to days. At the same latency as Qwen2.5-0.5B on the target hardware, our co-designed architecture achieves 19.42% lower perplexity on WikiText-2. To our knowledge, this is the first principled and operational framework for hardware co-design scaling laws in on-device LLM deployment. We will make the code and related checkpoints publicly available.
Abstract:Online Reinforcement Learning (RL) offers a promising avenue for complex image editing but is currently constrained by the scarcity of reliable and fine-grained reward signals. Existing evaluators frequently struggle with a critical perception gap we term "Attention Collapse," where models neglect cross-image comparisons and fail to capture fine-grained details, resulting in inaccurate perception and miscalibrated scores. To address these limitations, we propose SpatialReward, a reward model that enforces precise verification via explicit spatial reasoning. By anchoring reasoning to predicted edit regions, SpatialReward grounds semantic judgments in pixel-level evidence, significantly enhancing evaluative accuracy. Trained on a curated 260k spatial-aware dataset, our model achieves state-of-the-art performance on MMRB2 and EditReward-Bench, and outperforms proprietary evaluators on our proposed MultiEditReward-Bench. Furthermore, SpatialReward serves as a robust signal in online RL, boosting OmniGen2 by +0.90 on GEdit-Bench--surpassing the leading discriminative model and doubling the gain of GPT-4.1 (+0.45). These results demonstrate that spatial reasoning is essential for unlocking effective alignment in image editing.
Abstract:Metastatic Progression remains the leading cause of cancer-related mortality, yet predicting whether a primary tumor will metastasize and where it will disseminate directly from histopathology remains a fundamental challenge. Although whole-slide images (WSIs) provide rich morphological information, prior computational pathology approaches typically address metastatic status or site prediction as isolated tasks, and do not explicitly model the clinically sequential decision process of metastatic risk assessment followed by downstream site-specific evaluation. To address this research gap, we present a decision-aware, concept-aligned MIL framework, HistoMet, for prognostic metastatic outcome prediction from primary tumor WSIs. Our proposed framework adopts a two-module prediction pipeline in which the likelihood of metastatic progression from the primary tumor is first estimated, followed by conditional prediction of metastatic site for high-risk cases. To guide representation learning and improve clinical interpretability, our framework integrates linguistically defined and data-adaptive metastatic concepts through a pretrained pathology vision-language model. We evaluate HistoMet on a multi-institutional pan-cancer cohort of 6504 patients with metastasis follow-up and site annotations. Under clinically relevant high-sensitivity screening settings (95 percent sensitivity), HistoMet significantly reduces downstream workload while maintaining high metastatic risk recall. Conditional on metastatic cases, HistoMet achieves a macro F1 of 74.6 with a standard deviation of 1.3 and a macro one-vs-rest AUC of 92.1. These results demonstrate that explicitly modeling clinical decision structure enables robust and deployable prognostic prediction of metastatic progression and site tropism directly from primary tumor histopathology.
Abstract:Reward models are critical for reinforcement learning from human feedback, as they determine the alignment quality and reliability of generative models. For complex tasks such as image editing, reward models are required to capture global semantic consistency and implicit logical constraints beyond local similarity. Existing reward modeling approaches have clear limitations. Discriminative reward models align well with human preferences but struggle with complex semantics due to limited reasoning supervision. Generative reward models offer stronger semantic understanding and reasoning, but they are costly at inference time and difficult to align directly with human preferences. To this end, we propose Joint Reward Modeling (JRM), which jointly optimizes preference learning and language modeling on a shared vision-language backbone. This approach internalizes the semantic and reasoning capabilities of generative models into efficient discriminative representations, enabling fast and accurate evaluation. JRM achieves state-of-the-art results on MMRB2 and EditReward-Bench, and significantly improves stability and performance in downstream online reinforcement learning. These results show that joint training effectively bridges efficiency and semantic understanding in reward modeling.