Towards Within-Class Variation in Alzheimer's Disease Detection from Spontaneous Speech

Alzheimer's Disease (AD) detection has emerged as a promising research area that employs machine learning classification models to distinguish between individuals with AD and those without. Unlike conventional classification tasks, we identify within-class variation as a critical challenge in AD detection: individuals with AD exhibit a spectrum of cognitive impairments. Given that many AD detection tasks lack fine-grained labels, simplistic binary classification may overlook two crucial aspects: within-class differences and instance-level imbalance. The former compels the model to map AD samples with varying degrees of impairment to a single diagnostic label, disregarding certain changes in cognitive function. While the latter biases the model towards overrepresented severity levels. This work presents early efforts to address these challenges. We propose two novel methods: Soft Target Distillation (SoTD) and Instance-level Re-balancing (InRe), targeting two problems respectively. Experiments on the ADReSS and ADReSSo datasets demonstrate that the proposed methods significantly improve detection accuracy. Further analysis reveals that SoTD effectively harnesses the strengths of multiple component models, while InRe substantially alleviates model over-fitting. These findings provide insights for developing more robust and reliable AD detection models.

Purple-teaming LLMs with Adversarial Defender Training

Existing efforts in safeguarding LLMs are limited in actively exposing the vulnerabilities of the target LLM and readily adapting to newly emerging safety risks. To address this, we present Purple-teaming LLMs with Adversarial Defender training (PAD), a pipeline designed to safeguard LLMs by novelly incorporating the red-teaming (attack) and blue-teaming (safety training) techniques. In PAD, we automatically collect conversational data that cover the vulnerabilities of an LLM around specific safety risks in a self-play manner, where the attacker aims to elicit unsafe responses and the defender generates safe responses to these attacks. We then update both modules in a generative adversarial network style by training the attacker to elicit more unsafe responses and updating the defender to identify them and explain the unsafe reason. Experimental results demonstrate that PAD significantly outperforms existing baselines in both finding effective attacks and establishing a robust safe guardrail. Furthermore, our findings indicate that PAD excels in striking a balance between safety and overall model quality. We also reveal key challenges in safeguarding LLMs, including defending multi-turn attacks and the need for more delicate strategies to identify specific risks.

Enhancing Biomedical Knowledge Retrieval-Augmented Generation with Self-Rewarding Tree Search and Proximal Policy Optimization

Large Language Models (LLMs) have shown great potential in the biomedical domain with the advancement of retrieval-augmented generation (RAG). However, existing retrieval-augmented approaches face challenges in addressing diverse queries and documents, particularly for medical knowledge queries, resulting in sub-optimal performance. To address these limitations, we propose a novel plug-and-play LLM-based retrieval method called Self-Rewarding Tree Search (SeRTS) based on Monte Carlo Tree Search (MCTS) and a self-rewarding paradigm. By combining the reasoning capabilities of LLMs with the effectiveness of tree search, SeRTS boosts the zero-shot performance of retrieving high-quality and informative results for RAG. We further enhance retrieval performance by fine-tuning LLMs with Proximal Policy Optimization (PPO) objectives using the trajectories collected by SeRTS as feedback. Controlled experiments using the BioASQ-QA dataset with GPT-3.5-Turbo and LLama2-7b demonstrate that our method significantly improves the performance of the BM25 retriever and surpasses the strong baseline of self-reflection in both efficiency and scalability. Moreover, SeRTS generates higher-quality feedback for PPO training than self-reflection. Our proposed method effectively adapts LLMs to document retrieval tasks, enhancing their ability to retrieve highly relevant documents for RAG in the context of medical knowledge queries. This work presents a significant step forward in leveraging LLMs for accurate and comprehensive biomedical question answering.

Self-Tuning: Instructing LLMs to Effectively Acquire New Knowledge through Self-Teaching

Large language models (LLMs) often struggle to provide up-to-date information due to their one-time training and the constantly evolving nature of the world. To keep LLMs current, existing approaches typically involve continued pre-training on new documents. However, they frequently face difficulties in extracting stored knowledge. Motivated by the remarkable success of the Feynman Technique in efficient human learning, we introduce Self-Tuning, a learning framework aimed at improving an LLM's ability to effectively acquire new knowledge from raw documents through self-teaching. Specifically, we develop a Self-Teaching strategy that augments the documents with a set of knowledge-intensive tasks created in a self-supervised manner, focusing on three crucial aspects: memorization, comprehension, and self-reflection. Additionally, we introduce three Wiki-Newpages-2023-QA datasets to facilitate an in-depth analysis of an LLM's knowledge acquisition ability concerning memorization, extraction, and reasoning. Extensive experimental results on Llama2 family models reveal that Self-Tuning consistently exhibits superior performance across all knowledge acquisition tasks and excels in preserving previous knowledge.

Self-Alignment for Factuality: Mitigating Hallucinations in LLMs via Self-Evaluation

Despite showing increasingly human-like abilities, large language models (LLMs) often struggle with factual inaccuracies, i.e. "hallucinations", even when they hold relevant knowledge. To address these hallucinations, current approaches typically necessitate high-quality human factuality annotations. In this work, we explore Self-Alignment for Factuality, where we leverage the self-evaluation capability of an LLM to provide training signals that steer the model towards factuality. Specifically, we incorporate Self-Eval, a self-evaluation component, to prompt an LLM to validate the factuality of its own generated responses solely based on its internal knowledge. Additionally, we design Self-Knowledge Tuning (SK-Tuning) to augment the LLM's self-evaluation ability by improving the model's confidence estimation and calibration. We then utilize these self-annotated responses to fine-tune the model via Direct Preference Optimization algorithm. We show that the proposed self-alignment approach substantially enhances factual accuracy over Llama family models across three key knowledge-intensive tasks on TruthfulQA and BioGEN.

A Survey of the Evolution of Language Model-Based Dialogue Systems

Dialogue systems, including task-oriented_dialogue_system (TOD) and open-domain_dialogue_system (ODD), have undergone significant transformations, with language_models (LM) playing a central role. This survey delves into the historical trajectory of dialogue systems, elucidating their intricate relationship with advancements in language models by categorizing this evolution into four distinct stages, each marked by pivotal LM breakthroughs: 1) Early_Stage: characterized by statistical LMs, resulting in rule-based or machine-learning-driven dialogue_systems; 2) Independent development of TOD and ODD based on neural_language_models (NLM; e.g., LSTM and GRU), since NLMs lack intrinsic knowledge in their parameters; 3) fusion between different types of dialogue systems with the advert of pre-trained_language_models (PLMs), starting from the fusion between four_sub-tasks_within_TOD, and then TOD_with_ODD; and 4) current LLM-based_dialogue_system, wherein LLMs can be used to conduct TOD and ODD seamlessly. Thus, our survey provides a chronological perspective aligned with LM breakthroughs, offering a comprehensive review of state-of-the-art research outcomes. What's more, we focus on emerging topics and discuss open challenges, providing valuable insights into future directions for LLM-based_dialogue_systems. Through this exploration, we pave the way for a deeper_comprehension of the evolution, guiding future developments in LM-based dialogue_systems.

Rethinking Machine Ethics -- Can LLMs Perform Moral Reasoning through the Lens of Moral Theories?

Making moral judgments is an essential step toward developing ethical AI systems. Prevalent approaches are mostly implemented in a bottom-up manner, which uses a large set of annotated data to train models based on crowd-sourced opinions about morality. These approaches have been criticized for potentially overgeneralizing a limited group of annotators' moral stances and lacking explainability. In contrast, top-down approaches make moral judgments grounded in a set of principles. However, it remains conceptual due to the incapability of previous language models and the unsolved debate among moral principles. In this study, we propose a flexible framework to steer Large Language Models (LLMs) to perform moral reasoning with well-established moral theories from interdisciplinary research. The theory-guided top-down framework can incorporate various moral theories. Our experiments demonstrate the effectiveness of the proposed framework on datasets derived from moral theories. Furthermore, we show the alignment between different moral theories and existing morality datasets. Our analysis exhibits the potentials and flaws in existing resources (models and datasets) in developing explainable moral judgment-making systems.

SGP-TOD: Building Task Bots Effortlessly via Schema-Guided LLM Prompting

Building end-to-end task bots and maintaining their integration with new functionalities using minimal human efforts is a long-standing challenge in dialog research. Recently large language models (LLMs) have demonstrated exceptional proficiency in conversational engagement and adherence to instructions across various downstream tasks. In this work, we introduce SGP-TOD, Schema-Guided Prompting for building Task-Oriented Dialog systems effortlessly based on LLMs. Utilizing the symbolic knowledge -- task schema, we instruct fixed LLMs to generate appropriate responses on novel tasks, circumventing the need for training data. Specifically, SGP-TOD comprises three components: a LLM for engaging with users, a DST Prompter to aid the LLM with dialog state tracking, which is then used to retrieve database items, and a Policy Prompter to elicit proper responses adhering to the provided dialog policy. Experimental results on Multiwoz, RADDLE and STAR datasets show that our training-free strategy SGP-TOD, without any task-specific data, yields state-of-the-art (SOTA) zero-shot performance, greatly surpasses the few-shot approaches. In a domain-extension setting, SGP-TOD aptly adapts to new functionalities by merely adding supplementary schema rules. We make our code and data publicly available.

PanGu-Bot: Efficient Generative Dialogue Pre-training from Pre-trained Language Model

In this paper, we introduce PanGu-Bot, a Chinese pre-trained open-domain dialogue generation model based on a large pre-trained language model (PLM) PANGU-alpha (Zeng et al.,2021). Different from other pre-trained dialogue models trained over a massive amount of dialogue data from scratch, we aim to build a powerful dialogue model with relatively fewer data and computation costs by inheriting valuable language capabilities and knowledge from PLMs. To this end, we train PanGu-Bot from the large PLM PANGU-alpha, which has been proven well-performed on a variety of Chinese natural language tasks. We investigate different aspects of responses generated by PanGu-Bot, including response quality, knowledge, and safety. We show that PanGu-Bot outperforms state-of-the-art Chinese dialogue systems (CDIALGPT (Wang et al., 2020), EVA (Zhou et al., 2021)) w.r.t. the above three aspects. We also demonstrate that PanGu-Bot can be easily deployed to generate emotional responses without further training. Throughout our empirical analysis, we also point out that the PanGu-Bot response quality, knowledge correctness, and safety are still far from perfect, and further explorations are indispensable to building reliable and smart dialogue systems. Our model and code will be available at https://github.com/huawei-noah/Pretrained-Language-Model/tree/master/PanGu-Bot soon.

Towards Identifying Social Bias in Dialog Systems: Frame, Datasets, and Benchmarks

The research of open-domain dialog systems has been greatly prospered by neural models trained on large-scale corpora, however, such corpora often introduce various safety problems (e.g., offensive languages, biases, and toxic behaviors) that significantly hinder the deployment of dialog systems in practice. Among all these unsafe issues, addressing social bias is more complex as its negative impact on marginalized populations is usually expressed implicitly, thus requiring normative reasoning and rigorous analysis. In this paper, we focus our investigation on social bias detection of dialog safety problems. We first propose a novel Dial-Bias Frame for analyzing the social bias in conversations pragmatically, which considers more comprehensive bias-related analyses rather than simple dichotomy annotations. Based on the proposed framework, we further introduce CDail-Bias Dataset that, to our knowledge, is the first well-annotated Chinese social bias dialog dataset. In addition, we establish several dialog bias detection benchmarks at different label granularities and input types (utterance-level and context-level). We show that the proposed in-depth analyses together with these benchmarks in our Dial-Bias Frame are necessary and essential to bias detection tasks and can benefit building safe dialog systems in practice.