Abstract:While numerous machine unlearning (MU) methods have recently been developed with promising results in erasing the influence of forgotten data, classes, or concepts, they are also highly vulnerable-for example, simple fine-tuning can inadvertently reintroduce erased concepts. In this paper, we address this contradiction by examining the internal representations of unlearned models, in contrast to prior work that focuses primarily on output-level behavior. Our analysis shows that many state-of-the-art MU methods appear successful mainly due to a misalignment between last-layer features and the classifier, a phenomenon we call feature-classifier misalignment. In fact, hidden features remain highly discriminative, and simple linear probing can recover near-original accuracy. Assuming neural collapse in the original model, we further demonstrate that adjusting only the classifier can achieve negligible forget accuracy while preserving retain accuracy, and we corroborate this with experiments using classifier-only fine-tuning. Motivated by these findings, we propose MU methods based on a class-mean features (CMF) classifier, which explicitly enforces alignment between features and classifiers. Experiments on standard benchmarks show that CMF-based unlearning reduces forgotten information in representations while maintaining high retain accuracy, highlighting the need for faithful representation-level evaluation of MU.




Abstract:Large Language Models (LLMs) have shown great potential in the biomedical domain with the advancement of retrieval-augmented generation (RAG). However, existing retrieval-augmented approaches face challenges in addressing diverse queries and documents, particularly for medical knowledge queries, resulting in sub-optimal performance. To address these limitations, we propose a novel plug-and-play LLM-based retrieval method called Self-Rewarding Tree Search (SeRTS) based on Monte Carlo Tree Search (MCTS) and a self-rewarding paradigm. By combining the reasoning capabilities of LLMs with the effectiveness of tree search, SeRTS boosts the zero-shot performance of retrieving high-quality and informative results for RAG. We further enhance retrieval performance by fine-tuning LLMs with Proximal Policy Optimization (PPO) objectives using the trajectories collected by SeRTS as feedback. Controlled experiments using the BioASQ-QA dataset with GPT-3.5-Turbo and LLama2-7b demonstrate that our method significantly improves the performance of the BM25 retriever and surpasses the strong baseline of self-reflection in both efficiency and scalability. Moreover, SeRTS generates higher-quality feedback for PPO training than self-reflection. Our proposed method effectively adapts LLMs to document retrieval tasks, enhancing their ability to retrieve highly relevant documents for RAG in the context of medical knowledge queries. This work presents a significant step forward in leveraging LLMs for accurate and comprehensive biomedical question answering.