PathMoE: Interpretable Multimodal Interaction Experts for Pediatric Brain Tumor Classification

Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often fail to leverage the rich, complementary information found in clinical text and tissue microarchitecture. To this end, we propose PathMoE, an interpretable multimodal framework that integrates H\&E slides, pathology reports, and nuclei-level cell graphs via an interaction-aware mixture-of-experts architecture built on state-of-the-art foundation models for each modality. By training specialized experts to capture modality uniqueness, redundancy, and synergy, PathMoE employs an input-dependent gating mechanism that dynamically weights these interactions, providing sample-level interpretability. We evaluate our framework on two dataset-specific classification tasks on an internal pediatric brain tumor dataset (PBT) and external TCGA datasets. PathMoE improves macro-F1 from 0.762 to 0.799 (+0.037) on PBT when integrating WSI, text, and graph modalities; on TCGA, augmenting WSI with graph knowledge improves macro-F1 from 0.668 to 0.709 (+0.041). These results demonstrate significant performance gains over state-of-the-art image-only baselines while revealing the specific modality interactions driving individual predictions. This interpretability is particularly critical for rare tumor subtypes, where transparent model reasoning is essential for clinical trust and diagnostic validation.

Momentum Guidance: Plug-and-Play Guidance for Flow Models

Flow-based generative models have become a strong framework for high-quality generative modeling, yet pretrained models are rarely used in their vanilla conditional form: conditional samples without guidance often appear diffuse and lack fine-grained detail due to the smoothing effects of neural networks. Existing guidance techniques such as classifier-free guidance (CFG) improve fidelity but double the inference cost and typically reduce sample diversity. We introduce Momentum Guidance (MG), a new dimension of guidance that leverages the ODE trajectory itself. MG extrapolates the current velocity using an exponential moving average of past velocities and preserves the standard one-evaluation-per-step cost. It matches the effect of standard guidance without extra computation and can further improve quality when combined with CFG. Experiments demonstrate MG's effectiveness across benchmarks. Specifically, on ImageNet-256, MG achieves average improvements in FID of 36.68% without CFG and 25.52% with CFG across various sampling settings, attaining an FID of 1.597 at 64 sampling steps. Evaluations on large flow-based models like Stable Diffusion 3 and FLUX.1-dev further confirm consistent quality enhancements across standard metrics.

UrbanAlign: Post-hoc Semantic Calibration for VLM-Human Preference Alignment

Aligning vision-language model (VLM) outputs with human preferences in domain-specific tasks typically requires fine-tuning or reinforcement learning, both of which demand labelled data and GPU compute. We show that for subjective perception tasks, this alignment can be achieved without any model training: VLMs are already strong concept extractors but poor decision calibrators, and the gap can be closed externally. We propose a training-free post-hoc concept-bottleneck pipeline consisting of three tightly coupled stages: concept mining, multi-agent structured scoring, and geometric calibration, unified by an end-to-end dimension optimization loop. Interpretable evaluation dimensions are mined from a handful of human annotations; an Observer-Debater-Judge chain extracts robust continuous concept scores from a frozen VLM; and locally-weighted ridge regression on a hybrid visual-semantic manifold calibrates these scores against human ratings. Applied to urban perception as UrbanAlign, the framework achieves 72.2% accuracy ($κ=0.45$) on Place Pulse 2.0 across six categories, outperforming the best supervised baseline by +15.1 pp and uncalibrated VLM scoring by +16.3 pp, with full dimension-level interpretability and zero model-weight modification.

LingLanMiDian: Systematic Evaluation of LLMs on TCM Knowledge and Clinical Reasoning

Large language models (LLMs) are advancing rapidly in medical NLP, yet Traditional Chinese Medicine (TCM) with its distinctive ontology, terminology, and reasoning patterns requires domain-faithful evaluation. Existing TCM benchmarks are fragmented in coverage and scale and rely on non-unified or generation-heavy scoring that hinders fair comparison. We present the LingLanMiDian (LingLan) benchmark, a large-scale, expert-curated, multi-task suite that unifies evaluation across knowledge recall, multi-hop reasoning, information extraction, and real-world clinical decision-making. LingLan introduces a consistent metric design, a synonym-tolerant protocol for clinical labels, a per-dataset 400-item Hard subset, and a reframing of diagnosis and treatment recommendation into single-choice decision recognition. We conduct comprehensive, zero-shot evaluations on 14 leading open-source and proprietary LLMs, providing a unified perspective on their strengths and limitations in TCM commonsense knowledge understanding, reasoning, and clinical decision support; critically, the evaluation on Hard subset reveals a substantial gap between current models and human experts in TCM-specialized reasoning. By bridging fundamental knowledge and applied reasoning through standardized evaluation, LingLan establishes a unified, quantitative, and extensible foundation for advancing TCM LLMs and domain-specific medical AI research. All evaluation data and code are available at https://github.com/TCMAI-BJTU/LingLan and http://tcmnlp.com.

Seedance 1.5 pro: A Native Audio-Visual Joint Generation Foundation Model

Recent strides in video generation have paved the way for unified audio-visual generation. In this work, we present Seedance 1.5 pro, a foundational model engineered specifically for native, joint audio-video generation. Leveraging a dual-branch Diffusion Transformer architecture, the model integrates a cross-modal joint module with a specialized multi-stage data pipeline, achieving exceptional audio-visual synchronization and superior generation quality. To ensure practical utility, we implement meticulous post-training optimizations, including Supervised Fine-Tuning (SFT) on high-quality datasets and Reinforcement Learning from Human Feedback (RLHF) with multi-dimensional reward models. Furthermore, we introduce an acceleration framework that boosts inference speed by over 10X. Seedance 1.5 pro distinguishes itself through precise multilingual and dialect lip-syncing, dynamic cinematic camera control, and enhanced narrative coherence, positioning it as a robust engine for professional-grade content creation. Seedance 1.5 pro is now accessible on Volcano Engine at https://console.volcengine.com/ark/region:ark+cn-beijing/experience/vision?type=GenVideo.

Reframe Your Life Story: Interactive Narrative Therapist and Innovative Moment Assessment with Large Language Models

Recent progress in large language models (LLMs) has opened new possibilities for mental health support, yet current approaches lack realism in simulating specialized psychotherapy and fail to capture therapeutic progression over time. Narrative therapy, which helps individuals transform problematic life stories into empowering alternatives, remains underutilized due to limited access and social stigma. We address these limitations through a comprehensive framework with two core components. First, INT (Interactive Narrative Therapist) simulates expert narrative therapists by planning therapeutic stages, guiding reflection levels, and generating contextually appropriate expert-like responses. Second, IMA (Innovative Moment Assessment) provides a therapy-centric evaluation method that quantifies effectiveness by tracking "Innovative Moments" (IMs), critical narrative shifts in client speech signaling therapy progress. Experimental results on 260 simulated clients and 230 human participants reveal that INT consistently outperforms standard LLMs in therapeutic quality and depth. We further demonstrate the effectiveness of INT in synthesizing high-quality support conversations to facilitate social applications.

IMAGGarment-1: Fine-Grained Garment Generation for Controllable Fashion Design

This paper presents IMAGGarment-1, a fine-grained garment generation (FGG) framework that enables high-fidelity garment synthesis with precise control over silhouette, color, and logo placement. Unlike existing methods that are limited to single-condition inputs, IMAGGarment-1 addresses the challenges of multi-conditional controllability in personalized fashion design and digital apparel applications. Specifically, IMAGGarment-1 employs a two-stage training strategy to separately model global appearance and local details, while enabling unified and controllable generation through end-to-end inference. In the first stage, we propose a global appearance model that jointly encodes silhouette and color using a mixed attention module and a color adapter. In the second stage, we present a local enhancement model with an adaptive appearance-aware module to inject user-defined logos and spatial constraints, enabling accurate placement and visual consistency. To support this task, we release GarmentBench, a large-scale dataset comprising over 180K garment samples paired with multi-level design conditions, including sketches, color references, logo placements, and textual prompts. Extensive experiments demonstrate that our method outperforms existing baselines, achieving superior structural stability, color fidelity, and local controllability performance. The code and model are available at https://github.com/muzishen/IMAGGarment-1.

ClinicalBench: Can LLMs Beat Traditional ML Models in Clinical Prediction?

Large Language Models (LLMs) hold great promise to revolutionize current clinical systems for their superior capacities on medical text processing tasks and medical licensing exams. Meanwhile, traditional ML models such as SVM and XGBoost have still been mainly adopted in clinical prediction tasks. An emerging question is Can LLMs beat traditional ML models in clinical prediction? Thus, we build a new benchmark ClinicalBench to comprehensively study the clinical predictive modeling capacities of both general-purpose and medical LLMs, and compare them with traditional ML models. ClinicalBench embraces three common clinical prediction tasks, two databases, 14 general-purpose LLMs, 8 medical LLMs, and 11 traditional ML models. Through extensive empirical investigation, we discover that both general-purpose and medical LLMs, even with different model scales, diverse prompting or fine-tuning strategies, still cannot beat traditional ML models in clinical prediction yet, shedding light on their potential deficiency in clinical reasoning and decision-making. We call for caution when practitioners adopt LLMs in clinical applications. ClinicalBench can be utilized to bridge the gap between LLMs' development for healthcare and real-world clinical practice.

SS-Bench: A Benchmark for Social Story Generation and Evaluation

Children with Autism Spectrum Disorder (ASD) often misunderstand social situations and struggle to participate in daily routines. Psychology experts write Social Stories under strict constraints of structural clarity, descriptive orientation, and situational safety to enhance their abilities in these regimes. However, Social Stories are costly in creation and often limited in diversity and timeliness. As Large Language Models (LLMs) become increasingly powerful, there is a growing need for more automated, affordable, and accessible methods to generate Social Stories in real-time with broad coverage. Adapting LLMs to meet the unique and strict constraints of Social Stories is a challenging issue. To this end, we propose \textbf{SS-Bench}, a \textbf{S}ocial \textbf{S}tory \textbf{Bench}mark for generating and evaluating Social Stories. Specifically, we develop a constraint-driven strategy named \textbf{\textsc{StarSow}} to hierarchically prompt LLMs to generate Social Stories and build a benchmark, which has been validated through experiments to fine-tune smaller models for generating qualified Social Stories. Additionally, we introduce \textbf{Quality Assessment Criteria}, employed in human and GPT evaluations, to verify the effectiveness of the generated stories. We hope this work benefits the autism community and catalyzes future research focusing on particular groups.

Challenges in Binary Classification

Binary Classification plays an important role in machine learning. For linear classification, SVM is the optimal binary classification method. For nonlinear classification, the SVM algorithm needs to complete the classification task by using the kernel function. Although the SVM algorithm with kernel function is very effective, the selection of kernel function is empirical, which means that the kernel function may not be optimal. Therefore, it is worth studying how to obtain an optimal binary classifier. In this paper, the problem of finding the optimal binary classifier is considered as a variational problem. We design the objective function of this variational problem through the max-min problem of the (Euclidean) distance between two classes. For linear classification, it can be deduced that SVM is a special case of this variational problem framework. For Euclidean distance, it is proved that the proposed variational problem has some limitations for nonlinear classification. Therefore, how to design a more appropriate objective function to find the optimal binary classifier is still an open problem. Further, it's discussed some challenges and problems in finding the optimal classifier.