Abstract:The rapid adoption of data-driven methods in biomedicine has intensified concerns over privacy, governance, and regulation, limiting raw data sharing and hindering the assembly of representative cohorts for clinically relevant AI. This landscape necessitates practical, efficient privacy solutions, as cryptographic defenses often impose heavy overhead and differential privacy can degrade performance, leading to sub-optimal outcomes in real-world settings. Here, we present a lightweight federated learning method, INFL, based on Implicit Neural Representations that addresses these challenges. Our approach integrates plug-and-play, coordinate-conditioned modules into client models, embeds a secret key directly into the architecture, and supports seamless aggregation across heterogeneous sites. Across diverse biomedical omics tasks, including cohort-scale classification in bulk proteomics, regression for perturbation prediction in single-cell transcriptomics, and clustering in spatial transcriptomics and multi-omics with both public and private data, we demonstrate that INFL achieves strong, controllable privacy while maintaining utility, preserving the performance necessary for downstream scientific and clinical applications.
Abstract:Endoscopic video analysis is essential for early gastrointestinal screening but remains hindered by limited high-quality annotations. While self-supervised video pre-training shows promise, existing methods developed for natural videos prioritize dense spatio-temporal modeling and exhibit motion bias, overlooking the static, structured semantics critical to clinical decision-making. To address this challenge, we propose Focus-to-Perceive Representation Learning (FPRL), a cognition-inspired hierarchical framework that emulates clinical examination. FPRL first focuses on intra-frame lesion-centric regions to learn static semantics, and then perceives their evolution across frames to model contextual semantics. To achieve this, FPRL employs a hierarchical semantic modeling mechanism that explicitly distinguishes and collaboratively learns both types of semantics. Specifically, it begins by capturing static semantics via teacher-prior adaptive masking (TPAM) combined with multi-view sparse sampling. This approach mitigates redundant temporal dependencies and enables the model to concentrate on lesion-related local semantics. Following this, contextual semantics are derived through cross-view masked feature completion (CVMFC) and attention-guided temporal prediction (AGTP). These processes establish cross-view correspondences and effectively model structured inter-frame evolution, thereby reinforcing temporal semantic continuity while preserving global contextual integrity. Extensive experiments on 11 endoscopic video datasets show that FPRL achieves superior performance across diverse downstream tasks, demonstrating its effectiveness in endoscopic video representation learning. The code is available at https://github.com/MLMIP/FPRL.
Abstract:As agentic AI systems become increasingly capable of generating and optimizing GPU kernels, progress is constrained by benchmarks that reward speedup over software baselines rather than proximity to hardware-efficient execution. We present SOL-ExecBench, a benchmark of 235 CUDA kernel optimization problems extracted from 124 production and emerging AI models spanning language, diffusion, vision, audio, video, and hybrid architectures, targeting NVIDIA Blackwell GPUs. The benchmark covers forward and backward workloads across BF16, FP8, and NVFP4, including kernels whose best performance is expected to rely on Blackwell-specific capabilities. Unlike prior benchmarks that evaluate kernels primarily relative to software implementations, SOL-ExecBench measures performance against analytically derived Speed-of-Light (SOL) bounds computed by SOLAR, our pipeline for deriving hardware-grounded SOL bounds, yielding a fixed target for hardware-efficient optimization. We report a SOL Score that quantifies how much of the gap between a release-defined scoring baseline and the hardware SOL bound a candidate kernel closes. To support robust evaluation of agentic optimizers, we additionally provide a sandboxed harness with GPU clock locking, L2 cache clearing, isolated subprocess execution, and static analysis based checks against common reward-hacking strategies. SOL-ExecBench reframes GPU kernel benchmarking from beating a mutable software baseline to closing the remaining gap to hardware Speed-of-Light.
Abstract:We present ECHO, an edge--cloud framework for language-driven whole-body control of humanoid robots. A cloud-hosted diffusion-based text-to-motion generator synthesizes motion references from natural language instructions, while an edge-deployed reinforcement-learning tracker executes them in closed loop on the robot. The two modules are bridged by a compact, robot-native 38-dimensional motion representation that encodes joint angles, root planar velocity, root height, and a continuous 6D root orientation per frame, eliminating inference-time retargeting from human body models and remaining directly compatible with low-level PD control. The generator adopts a 1D convolutional UNet with cross-attention conditioned on CLIP-encoded text features; at inference, DDIM sampling with 10 denoising steps and classifier-free guidance produces motion sequences in approximately one second on a cloud GPU. The tracker follows a Teacher--Student paradigm: a privileged teacher policy is distilled into a lightweight student equipped with an evidential adaptation module for sim-to-real transfer, further strengthened by morphological symmetry constraints and domain randomization. An autonomous fall recovery mechanism detects falls via onboard IMU readings and retrieves recovery trajectories from a pre-built motion library. We evaluate ECHO on a retargeted HumanML3D benchmark, where it achieves strong generation quality (FID 0.029, R-Precision Top-1 0.686) under a unified robot-domain evaluator, while maintaining high motion safety and trajectory consistency. Real-world experiments on a Unitree G1 humanoid demonstrate stable execution of diverse text commands with zero hardware fine-tuning.
Abstract:Large Language Models (LLMs) excel at general code generation, yet translating natural-language trading intents into correct option strategies remains challenging. Real-world option design requires reasoning over massive, multi-dimensional option chain data with strict constraints, which often overwhelms direct generation methods. We introduce the Option Query Language (OQL), a domain-specific intermediate representation that abstracts option markets into high-level primitives under grammatical rules, enabling LLMs to function as reliable semantic parsers rather than free-form programmers. OQL queries are then validated and executed deterministically by an engine to instantiate executable strategies. We also present a new dataset for this task and demonstrate that our neuro-symbolic pipeline significantly improves execution accuracy and logical consistency over direct baselines.
Abstract:Accurate segmentation of aortic dissection (AD) lumens in CT angiography (CTA) is essential for quantitative morphological assessment and clinical decision-making. However, reliable 3D delineation remains challenging due to limited long-range context modeling, which compromises inter-slice coherence, and insufficient structural discrimination under low-contrast conditions. To address these limitations, we propose BiM-GeoAttn-Net, a lightweight framework that integrates linear-time depth-wise state-space modeling with geometry-aware vessel refinement. Our approach is featured by Bidirectional Depth Mamba (BiM) to efficiently capture cross-slice dependencies and Geometry-Aware Vessel Attention (GeoAttn) module that employs orientation-sensitive anisotropic filtering to refine tubular structures and sharpen ambiguous boundaries. Extensive experiments on a multi-source AD CTA dataset demonstrate that BiM-GeoAttn-Net achieves a Dice score of 93.35% and an HD95 of 12.36 mm, outperforming representative CNN-, Transformer-, and SSM-based baselines in overlap metrics while maintaining competitive boundary accuracy. These results suggest that coupling linear-time depth modeling with geometry-aware refinement provides an effective, computationally efficient solution for robust 3D AD segmentation.
Abstract:In this report, we introduce Xiaomi-Robotics-0, an advanced vision-language-action (VLA) model optimized for high performance and fast and smooth real-time execution. The key to our method lies in a carefully designed training recipe and deployment strategy. Xiaomi-Robotics-0 is first pre-trained on large-scale cross-embodiment robot trajectories and vision-language data, endowing it with broad and generalizable action-generation capabilities while avoiding catastrophic forgetting of the visual-semantic knowledge of the underlying pre-trained VLM. During post-training, we propose several techniques for training the VLA model for asynchronous execution to address the inference latency during real-robot rollouts. During deployment, we carefully align the timesteps of consecutive predicted action chunks to ensure continuous and seamless real-time rollouts. We evaluate Xiaomi-Robotics-0 extensively in simulation benchmarks and on two challenging real-robot tasks that require precise and dexterous bimanual manipulation. Results show that our method achieves state-of-the-art performance across all simulation benchmarks. Moreover, Xiaomi-Robotics-0 can roll out fast and smoothly on real robots using a consumer-grade GPU, achieving high success rates and throughput on both real-robot tasks. To facilitate future research, code and model checkpoints are open-sourced at https://xiaomi-robotics-0.github.io
Abstract:Shapley values are widely used for model-agnostic data valuation and feature attribution, yet they implicitly assume contributors are interchangeable. This can be problematic when contributors are dependent (e.g., reused/augmented data or causal feature orderings) or when contributions should be adjusted by factors such as trust or risk. We propose Priority-Aware Shapley Value (PASV), which incorporates both hard precedence constraints and soft, contributor-specific priority weights. PASV is applicable to general precedence structures, recovers precedence-only and weight-only Shapley variants as special cases, and is uniquely characterized by natural axioms. We develop an efficient adjacent-swap Metropolis-Hastings sampler for scalable Monte Carlo estimation and analyze limiting regimes induced by extreme priority weights. Experiments on data valuation (MNIST/CIFAR10) and feature attribution (Census Income) demonstrate more structure-faithful allocations and a practical sensitivity analysis via our proposed "priority sweeping".
Abstract:Detecting uncivil language is crucial for maintaining safe, inclusive, and democratic online spaces. Yet existing classifiers often misinterpret posts containing uncivil cues but expressing civil intents, leading to inflated estimates of harmful incivility online. We introduce LinGO, a linguistic graph optimization framework for large language models (LLMs) that leverages linguistic structures and optimization techniques to classify multi-class intents of incivility that use various direct and indirect expressions. LinGO decomposes language into multi-step linguistic components, identifies targeted steps that cause the most errors, and iteratively optimizes prompt and/or example components for targeted steps. We evaluate it using a dataset collected during the 2022 Brazilian presidential election, encompassing four forms of political incivility: Impoliteness (IMP), Hate Speech and Stereotyping (HSST), Physical Harm and Violent Political Rhetoric (PHAVPR), and Threats to Democratic Institutions and Values (THREAT). Each instance is annotated with six types of civil/uncivil intent. We benchmark LinGO using three cost-efficient LLMs: GPT-5-mini, Gemini 2.5 Flash-Lite, and Claude 3 Haiku, and four optimization techniques: TextGrad, AdalFlow, DSPy, and Retrieval-Augmented Generation (RAG). The results show that, across all models, LinGO consistently improves accuracy and weighted F1 compared with zero-shot, chain-of-thought, direct optimization, and fine-tuning baselines. RAG is the strongest optimization technique and, when paired with Gemini model, achieves the best overall performance. These findings demonstrate that incorporating multi-step linguistic components into LLM instructions and optimize targeted components can help the models explain complex semantic meanings, which can be extended to other complex semantic explanation tasks in the future.
Abstract:Reinforcement learning with verifiable rewards has shown notable effectiveness in enhancing large language models (LLMs) reasoning performance, especially in mathematics tasks. However, such improvements often come with reduced outcome diversity, where the model concentrates probability mass on a narrow set of solutions. Motivated by diminishing-returns principles, we introduce a set level diversity objective defined over sampled trajectories using kernelized similarity. Our approach derives a leave-one-out marginal contribution for each sampled trajectory and integrates this objective as a plug-in advantage shaping term for policy optimization. We further investigate the contribution of a single trajectory to language model diversity within a distribution perturbation framework. This analysis theoretically confirms a monotonicity property, proving that rarer trajectories yield consistently higher marginal contributions to the global diversity. Extensive experiments across a range of model scales demonstrate the effectiveness of our proposed algorithm, consistently outperforming strong baselines in both Pass@1 and Pass@K across various benchmarks.