PROVCREATOR: Synthesizing Complex Heterogenous Graphs with Node and Edge Attributes

The rise of graph-structured data has driven interest in graph learning and synthetic data generation. While successful in text and image domains, synthetic graph generation remains challenging -- especially for real-world graphs with complex, heterogeneous schemas. Existing research has focused mostly on homogeneous structures with simple attributes, limiting their usefulness and relevance for application domains requiring semantic fidelity. In this research, we introduce ProvCreator, a synthetic graph framework designed for complex heterogeneous graphs with high-dimensional node and edge attributes. ProvCreator formulates graph synthesis as a sequence generation task, enabling the use of transformer-based large language models. It features a versatile graph-to-sequence encoder-decoder that 1. losslessly encodes graph structure and attributes, 2. efficiently compresses large graphs for contextual modeling, and 3. supports end-to-end, learnable graph generation. To validate our research, we evaluate ProvCreator on two challenging domains: system provenance graphs in cybersecurity and knowledge graphs from IntelliGraph Benchmark Dataset. In both cases, ProvCreator captures intricate dependencies between structure and semantics, enabling the generation of realistic and privacy-aware synthetic datasets.

Reading Between the Lines: Combining Pause Dynamics and Semantic Coherence for Automated Assessment of Thought Disorder

Formal thought disorder (FTD), a hallmark of schizophrenia spectrum disorders, manifests as incoherent speech and poses challenges for clinical assessment. Traditional clinical rating scales, though validated, are resource-intensive and lack scalability. Automated speech analysis with automatic speech recognition (ASR) allows for objective quantification of linguistic and temporal features of speech, offering scalable alternatives. The use of utterance timestamps in ASR captures pause dynamics, which are thought to reflect the cognitive processes underlying speech production. However, the utility of integrating these ASR-derived features for assessing FTD severity requires further evaluation. This study integrates pause features with semantic coherence metrics across three datasets: naturalistic self-recorded diaries (AVH, n = 140), structured picture descriptions (TOPSY, n = 72), and dream narratives (PsyCL, n = 43). We evaluated pause related features alongside established coherence measures, using support vector regression (SVR) to predict clinical FTD scores. Key findings demonstrate that pause features alone robustly predict the severity of FTD. Integrating pause features with semantic coherence metrics enhanced predictive performance compared to semantic-only models, with integration of independent models achieving correlations up to \r{ho} = 0.649 and AUC = 83.71% for severe cases detection (TOPSY, with best \r{ho} = 0.584 and AUC = 79.23% for semantic-only models). The performance gains from semantic and pause features integration held consistently across all contexts, though the nature of pause patterns was dataset-dependent. These findings suggest that frameworks combining temporal and semantic analyses provide a roadmap for refining the assessment of disorganized speech and advance automated speech analysis in psychosis.

Convergent and divergent connectivity patterns of the arcuate fasciculus in macaques and humans

The organization and connectivity of the arcuate fasciculus (AF) in nonhuman primates remain contentious, especially concerning how its anatomy diverges from that of humans. Here, we combined cross-scale single-neuron tracing - using viral-based genetic labeling and fluorescence micro-optical sectioning tomography in macaques (n = 4; age 3 - 11 years) - with whole-brain tractography from 11.7T diffusion MRI. Complemented by spectral embedding analysis of 7.0T MRI in humans, we performed a comparative connectomic analysis of the AF across species. We demonstrate that the macaque AF originates in the temporal-parietal cortex, traverses the auditory cortex and parietal operculum, and projects into prefrontal regions. In contrast, the human AF exhibits greater expansion into the middle temporal gyrus and stronger prefrontal and parietal operculum connectivity - divergences quantified by Kullback-Leibler analysis that likely underpin the evolutionary specialization of human language networks. These interspecies differences - particularly the human AF's broader temporal integration and strengthened frontoparietal linkages - suggest a connectivity-based substrate for the emergence of advanced language processing unique to humans. Furthermore, our findings offer a neuroanatomical framework for understanding AF-related disorders such as aphasia and dyslexia, where aberrant connectivity disrupts language function.

Alternating Gradient Flows: A Theory of Feature Learning in Two-layer Neural Networks

What features neural networks learn, and how, remains an open question. In this paper, we introduce Alternating Gradient Flows (AGF), an algorithmic framework that describes the dynamics of feature learning in two-layer networks trained from small initialization. Prior works have shown that gradient flow in this regime exhibits a staircase-like loss curve, alternating between plateaus where neurons slowly align to useful directions and sharp drops where neurons rapidly grow in norm. AGF approximates this behavior as an alternating two-step process: maximizing a utility function over dormant neurons and minimizing a cost function over active ones. AGF begins with all neurons dormant. At each round, a dormant neuron activates, triggering the acquisition of a feature and a drop in the loss. AGF quantifies the order, timing, and magnitude of these drops, matching experiments across architectures. We show that AGF unifies and extends existing saddle-to-saddle analyses in fully connected linear networks and attention-only linear transformers, where the learned features are singular modes and principal components, respectively. In diagonal linear networks, we prove AGF converges to gradient flow in the limit of vanishing initialization. Applying AGF to quadratic networks trained to perform modular addition, we give the first complete characterization of the training dynamics, revealing that networks learn Fourier features in decreasing order of coefficient magnitude. Altogether, AGF offers a promising step towards understanding feature learning in neural networks.

PCIE_Pose Solution for EgoExo4D Pose and Proficiency Estimation Challenge

This report introduces our team's (PCIE_EgoPose) solutions for the EgoExo4D Pose and Proficiency Estimation Challenges at CVPR2025. Focused on the intricate task of estimating 21 3D hand joints from RGB egocentric videos, which are complicated by subtle movements and frequent occlusions, we developed the Hand Pose Vision Transformer (HP-ViT+). This architecture synergizes a Vision Transformer and a CNN backbone, using weighted fusion to refine the hand pose predictions. For the EgoExo4D Body Pose Challenge, we adopted a multimodal spatio-temporal feature integration strategy to address the complexities of body pose estimation across dynamic contexts. Our methods achieved remarkable performance: 8.31 PA-MPJPE in the Hand Pose Challenge and 11.25 MPJPE in the Body Pose Challenge, securing championship titles in both competitions. We extended our pose estimation solutions to the Proficiency Estimation task, applying core technologies such as transformer-based architectures. This extension enabled us to achieve a top-1 accuracy of 0.53, a SOTA result, in the Demonstrator Proficiency Estimation competition.

PCIE_Interaction Solution for Ego4D Social Interaction Challenge

This report presents our team's PCIE_Interaction solution for the Ego4D Social Interaction Challenge at CVPR 2025, addressing both Looking At Me (LAM) and Talking To Me (TTM) tasks. The challenge requires accurate detection of social interactions between subjects and the camera wearer, with LAM relying exclusively on face crop sequences and TTM combining speaker face crops with synchronized audio segments. In the LAM track, we employ face quality enhancement and ensemble methods. For the TTM task, we extend visual interaction analysis by fusing audio and visual cues, weighted by a visual quality score. Our approach achieved 0.81 and 0.71 mean average precision (mAP) on the LAM and TTM challenges leader board. Code is available at https://github.com/KanokphanL/PCIE_Ego4D_Social_Interaction

PathFL: Multi-Alignment Federated Learning for Pathology Image Segmentation

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and impedes the development of generalizable segmentation models. In this paper, we propose PathFL, a novel multi-alignment Federated Learning framework for pathology image segmentation that addresses these challenges through three-level alignment strategies of image, feature, and model aggregation. Firstly, at the image level, a collaborative style enhancement module aligns and diversifies local data by facilitating style information exchange across clients. Secondly, at the feature level, an adaptive feature alignment module ensures implicit alignment in the representation space by infusing local features with global insights, promoting consistency across heterogeneous client features learning. Finally, at the model aggregation level, a stratified similarity aggregation strategy hierarchically aligns and aggregates models on the server, using layer-specific similarity to account for client discrepancies and enhance global generalization. Comprehensive evaluations on four sets of heterogeneous pathology image datasets, encompassing cross-source, cross-modality, cross-organ, and cross-scanner variations, validate the effectiveness of our PathFL in achieving better performance and robustness against data heterogeneity.

Four Eyes Are Better Than Two: Harnessing the Collaborative Potential of Large Models via Differentiated Thinking and Complementary Ensembles

In this paper, we present the runner-up solution for the Ego4D EgoSchema Challenge at CVPR 2025 (Confirmed on May 20, 2025). Inspired by the success of large models, we evaluate and leverage leading accessible multimodal large models and adapt them to video understanding tasks via few-shot learning and model ensemble strategies. Specifically, diversified prompt styles and process paradigms are systematically explored and evaluated to effectively guide the attention of large models, fully unleashing their powerful generalization and adaptability abilities. Experimental results demonstrate that, with our carefully designed approach, directly utilizing an individual multimodal model already outperforms the previous state-of-the-art (SOTA) method which includes several additional processes. Besides, an additional stage is further introduced that facilitates the cooperation and ensemble of periodic results, which achieves impressive performance improvements. We hope this work serves as a valuable reference for the practical application of large models and inspires future research in the field.

Generative Models in Computational Pathology: A Comprehensive Survey on Methods, Applications, and Challenges

Generative modeling has emerged as a promising direction in computational pathology, offering capabilities such as data-efficient learning, synthetic data augmentation, and multimodal representation across diverse diagnostic tasks. This review provides a comprehensive synthesis of recent progress in the field, organized into four key domains: image generation, text generation, multimodal image-text generation, and other generative applications, including spatial simulation and molecular inference. By analyzing over 150 representative studies, we trace the evolution of generative architectures from early generative adversarial networks to recent advances in diffusion models and foundation models with generative capabilities. We further examine the datasets and evaluation protocols commonly used in this domain and highlight ongoing limitations, including challenges in generating high-fidelity whole slide images, clinical interpretability, and concerns related to the ethical and legal implications of synthetic data. The review concludes with a discussion of open challenges and prospective research directions, with an emphasis on developing unified, multimodal, and clinically deployable generative systems. This work aims to provide a foundational reference for researchers and practitioners developing and applying generative models in computational pathology.

Can Language Models Understand Social Behavior in Clinical Conversations?

Effective communication between providers and their patients influences health and care outcomes. The effectiveness of such conversations has been linked not only to the exchange of clinical information, but also to a range of interpersonal behaviors; commonly referred to as social signals, which are often conveyed through non-verbal cues and shape the quality of the patient-provider relationship. Recent advances in large language models (LLMs) have demonstrated an increasing ability to infer emotional and social behaviors even when analyzing only textual information. As automation increases also in clinical settings, such as for transcription of patient-provider conversations, there is growing potential for LLMs to automatically analyze and extract social behaviors from these interactions. To explore the foundational capabilities of LLMs in tracking social signals in clinical dialogue, we designed task-specific prompts and evaluated model performance across multiple architectures and prompting styles using a highly imbalanced, annotated dataset spanning 20 distinct social signals such as provider dominance, patient warmth, etc. We present the first system capable of tracking all these 20 coded signals, and uncover patterns in LLM behavior. Further analysis of model configurations and clinical context provides insights for enhancing LLM performance on social signal processing tasks in healthcare settings.