SAFER: A Calibrated Risk-Aware Multimodal Recommendation Model for Dynamic Treatment Regimes

Dynamic treatment regimes (DTRs) are critical to precision medicine, optimizing long-term outcomes through personalized, real-time decision-making in evolving clinical contexts, but require careful supervision for unsafe treatment risks. Existing efforts rely primarily on clinician-prescribed gold standards despite the absence of a known optimal strategy, and predominantly using structured EHR data without extracting valuable insights from clinical notes, limiting their reliability for treatment recommendations. In this work, we introduce SAFER, a calibrated risk-aware tabular-language recommendation framework for DTR that integrates both structured EHR and clinical notes, enabling them to learn from each other, and addresses inherent label uncertainty by assuming ambiguous optimal treatment solution for deceased patients. Moreover, SAFER employs conformal prediction to provide statistical guarantees, ensuring safe treatment recommendations while filtering out uncertain predictions. Experiments on two publicly available sepsis datasets demonstrate that SAFER outperforms state-of-the-art baselines across multiple recommendation metrics and counterfactual mortality rate, while offering robust formal assurances. These findings underscore SAFER potential as a trustworthy and theoretically grounded solution for high-stakes DTR applications.

FreeTimeGS: Free Gaussian Primitives at Anytime and Anywhere for Dynamic Scene Reconstruction

This paper addresses the challenge of reconstructing dynamic 3D scenes with complex motions. Some recent works define 3D Gaussian primitives in the canonical space and use deformation fields to map canonical primitives to observation spaces, achieving real-time dynamic view synthesis. However, these methods often struggle to handle scenes with complex motions due to the difficulty of optimizing deformation fields. To overcome this problem, we propose FreeTimeGS, a novel 4D representation that allows Gaussian primitives to appear at arbitrary time and locations. In contrast to canonical Gaussian primitives, our representation possesses the strong flexibility, thus improving the ability to model dynamic 3D scenes. In addition, we endow each Gaussian primitive with an motion function, allowing it to move to neighboring regions over time, which reduces the temporal redundancy. Experiments results on several datasets show that the rendering quality of our method outperforms recent methods by a large margin. Project page: https://zju3dv.github.io/freetimegs/ .

Challenger: Affordable Adversarial Driving Video Generation

Generating photorealistic driving videos has seen significant progress recently, but current methods largely focus on ordinary, non-adversarial scenarios. Meanwhile, efforts to generate adversarial driving scenarios often operate on abstract trajectory or BEV representations, falling short of delivering realistic sensor data that can truly stress-test autonomous driving (AD) systems. In this work, we introduce Challenger, a framework that produces physically plausible yet photorealistic adversarial driving videos. Generating such videos poses a fundamental challenge: it requires jointly optimizing over the space of traffic interactions and high-fidelity sensor observations. Challenger makes this affordable through two techniques: (1) a physics-aware multi-round trajectory refinement process that narrows down candidate adversarial maneuvers, and (2) a tailored trajectory scoring function that encourages realistic yet adversarial behavior while maintaining compatibility with downstream video synthesis. As tested on the nuScenes dataset, Challenger generates a diverse range of aggressive driving scenarios-including cut-ins, sudden lane changes, tailgating, and blind spot intrusions-and renders them into multiview photorealistic videos. Extensive evaluations show that these scenarios significantly increase the collision rate of state-of-the-art end-to-end AD models (UniAD, VAD, SparseDrive, and DiffusionDrive), and importantly, adversarial behaviors discovered for one model often transfer to others.

Sage Deer: A Super-Aligned Driving Generalist Is Your Copilot

The intelligent driving cockpit, an important part of intelligent driving, needs to match different users' comfort, interaction, and safety needs. This paper aims to build a Super-Aligned and GEneralist DRiving agent, SAGE DeeR. Sage Deer achieves three highlights: (1) Super alignment: It achieves different reactions according to different people's preferences and biases. (2) Generalist: It can understand the multi-view and multi-mode inputs to reason the user's physiological indicators, facial emotions, hand movements, body movements, driving scenarios, and behavioral decisions. (3) Self-Eliciting: It can elicit implicit thought chains in the language space to further increase generalist and super-aligned abilities. Besides, we collected multiple data sets and built a large-scale benchmark. This benchmark measures the deer's perceptual decision-making ability and the super alignment's accuracy.

Convert Language Model into a Value-based Strategic Planner

Emotional support conversation (ESC) aims to alleviate the emotional distress of individuals through effective conversations. Although large language models (LLMs) have obtained remarkable progress on ESC, most of these studies might not define the diagram from the state model perspective, therefore providing a suboptimal solution for long-term satisfaction. To address such an issue, we leverage the Q-learning on LLMs, and propose a framework called straQ*. Our framework allows a plug-and-play LLM to bootstrap the planning during ESC, determine the optimal strategy based on long-term returns, and finally guide the LLM to response. Substantial experiments on ESC datasets suggest that straQ* outperforms many baselines, including direct inference, self-refine, chain of thought, finetuning, and finite state machines.

FiSMiness: A Finite State Machine Based Paradigm for Emotional Support Conversations

Emotional support conversation (ESC) aims to alleviate the emotional distress of individuals through effective conversations. Although large language models (LLMs) have obtained remarkable progress on ESC, most of these studies might not define the diagram from the state model perspective, therefore providing a suboptimal solution for long-term satisfaction. To address such an issue, we leverage the Finite State Machine (FSM) on LLMs, and propose a framework called FiSMiness. Our framework allows a single LLM to bootstrap the planning during ESC, and self-reason the seeker's emotion, support strategy and the final response upon each conversational turn. Substantial experiments on ESC datasets suggest that FiSMiness outperforms many baselines, including direct inference, self-refine, chain of thought, finetuning, and external-assisted methods, even those with many more parameters.

Enabling Inclusive Systematic Reviews: Incorporating Preprint Articles with Large Language Model-Driven Evaluations

Background. Systematic reviews in comparative effectiveness research require timely evidence synthesis. Preprints accelerate knowledge dissemination but vary in quality, posing challenges for systematic reviews. Methods. We propose AutoConfidence (automated confidence assessment), an advanced framework for predicting preprint publication, which reduces reliance on manual curation and expands the range of predictors, including three key advancements: (1) automated data extraction using natural language processing techniques, (2) semantic embeddings of titles and abstracts, and (3) large language model (LLM)-driven evaluation scores. Additionally, we employed two prediction models: a random forest classifier for binary outcome and a survival cure model that predicts both binary outcome and publication risk over time. Results. The random forest classifier achieved AUROC 0.692 with LLM-driven scores, improving to 0.733 with semantic embeddings and 0.747 with article usage metrics. The survival cure model reached AUROC 0.716 with LLM-driven scores, improving to 0.731 with semantic embeddings. For publication risk prediction, it achieved a concordance index of 0.658, increasing to 0.667 with semantic embeddings. Conclusion. Our study advances the framework for preprint publication prediction through automated data extraction and multiple feature integration. By combining semantic embeddings with LLM-driven evaluations, AutoConfidence enhances predictive performance while reducing manual annotation burden. The framework has the potential to facilitate systematic incorporation of preprint articles in evidence-based medicine, supporting researchers in more effective evaluation and utilization of preprint resources.

Degradation Alchemy: Self-Supervised Unknown-to-Known Transformation for Blind Hyperspectral Image Fusion

Hyperspectral image (HSI) fusion is an efficient technique that combines low-resolution HSI (LR-HSI) and high-resolution multispectral images (HR-MSI) to generate high-resolution HSI (HR-HSI). Existing supervised learning methods (SLMs) can yield promising results when test data degradation matches the training ones, but they face challenges in generalizing to unknown degradations. To unleash the potential and generalization ability of SLMs, we propose a novel self-supervised unknown-to-known degradation transformation framework (U2K) for blind HSI fusion, which adaptively transforms unknown degradation into the same type of degradation as those handled by pre-trained SLMs. Specifically, the proposed U2K framework consists of: (1) spatial and spectral Degradation Wrapping (DW) modules that map HR-HSI to unknown degraded HR-MSI and LR-HSI, and (2) Degradation Transformation (DT) modules that convert these wrapped data into predefined degradation patterns. The transformed HR-MSI and LR-HSI pairs are then processed by a pre-trained network to reconstruct the target HR-HSI. We train the U2K framework in a self-supervised manner using consistency loss and greedy alternating optimization, significantly improving the flexibility of blind HSI fusion. Extensive experiments confirm the effectiveness of our proposed U2K framework in boosting the adaptability of five existing SLMs under various degradation settings and surpassing state-of-the-art blind methods.

Learn then Decide: A Learning Approach for Designing Data Marketplaces

As data marketplaces become increasingly central to the digital economy, it is crucial to design efficient pricing mechanisms that optimize revenue while ensuring fair and adaptive pricing. We introduce the Maximum Auction-to-Posted Price (MAPP) mechanism, a novel two-stage approach that first estimates the bidders' value distribution through auctions and then determines the optimal posted price based on the learned distribution. We establish that MAPP is individually rational and incentive-compatible, ensuring truthful bidding while balancing revenue maximization with minimal price discrimination. MAPP achieves a regret of $O_p(n^{-1})$ when incorporating historical bid data, where $n$ is the number of bids in the current round. It outperforms existing methods while imposing weaker distributional assumptions. For sequential dataset sales over $T$ rounds, we propose an online MAPP mechanism that dynamically adjusts pricing across datasets with varying value distributions. Our approach achieves no-regret learning, with the average cumulative regret converging at a rate of $O_p(T^{-1/2}(\log T)^2)$. We validate the effectiveness of MAPP through simulations and real-world data from the FCC AWS-3 spectrum auction.

MP-HSIR: A Multi-Prompt Framework for Universal Hyperspectral Image Restoration

Hyperspectral images (HSIs) often suffer from diverse and unknown degradations during imaging, leading to severe spectral and spatial distortions. Existing HSI restoration methods typically rely on specific degradation assumptions, limiting their effectiveness in complex scenarios. In this paper, we propose MP-HSIR, a novel multi-prompt framework that effectively integrates spectral, textual, and visual prompts to achieve universal HSI restoration across diverse degradation types and intensities. Specifically, we develop a prompt-guided spatial-spectral transformer, which incorporates spatial self-attention and a prompt-guided dual-branch spectral self-attention. Since degradations affect spectral features differently, we introduce spectral prompts in the local spectral branch to provide universal low-rank spectral patterns as prior knowledge for enhancing spectral reconstruction. Furthermore, the text-visual synergistic prompt fuses high-level semantic representations with fine-grained visual features to encode degradation information, thereby guiding the restoration process. Extensive experiments on 9 HSI restoration tasks, including all-in-one scenarios, generalization tests, and real-world cases, demonstrate that MP-HSIR not only consistently outperforms existing all-in-one methods but also surpasses state-of-the-art task-specific approaches across multiple tasks. The code and models will be released at https://github.com/ZhehuiWu/MP-HSIR.