FAME: Adaptive Functional Attention with Expert Routing for Function-on-Function Regression

Functional data play a pivotal role across science and engineering, yet their infinite-dimensional nature makes representation learning challenging. Conventional statistical models depend on pre-chosen basis expansions or kernels, limiting the flexibility of data-driven discovery, while many deep-learning pipelines treat functions as fixed-grid vectors, ignoring inherent continuity. In this paper, we introduce Functional Attention with a Mixture-of-Experts (FAME), an end-to-end, fully data-driven framework for function-on-function regression. FAME forms continuous attention by coupling a bidirectional neural controlled differential equation with MoE-driven vector fields to capture intra-functional continuity, and further fuses change to inter-functional dependencies via multi-head cross attention. Extensive experiments on synthetic and real-world functional-regression benchmarks show that FAME achieves state-of-the-art accuracy, strong robustness to arbitrarily sampled discrete observations of functions.

Empowering Clinical Trial Design through AI: A Randomized Evaluation of PowerGPT

Sample size calculations for power analysis are critical for clinical research and trial design, yet their complexity and reliance on statistical expertise create barriers for many researchers. We introduce PowerGPT, an AI-powered system integrating large language models (LLMs) with statistical engines to automate test selection and sample size estimation in trial design. In a randomized trial to evaluate its effectiveness, PowerGPT significantly improved task completion rates (99.3% vs. 88.9% for test selection, 99.3% vs. 77.8% for sample size calculation) and accuracy (94.1% vs. 55.4% in sample size estimation, p < 0.001), while reducing average completion time (4.0 vs. 9.3 minutes, p < 0.001). These gains were consistent across various statistical tests and benefited both statisticians and non-statisticians as well as bridging expertise gaps. Already under deployment across multiple institutions, PowerGPT represents a scalable AI-driven approach that enhances accessibility, efficiency, and accuracy in statistical power analysis for clinical research.

Dream to Chat: Model-based Reinforcement Learning on Dialogues with User Belief Modeling

World models have been widely utilized in robotics, gaming, and auto-driving. However, their applications on natural language tasks are relatively limited. In this paper, we construct the dialogue world model, which could predict the user's emotion, sentiment, and intention, and future utterances. By defining a POMDP, we argue emotion, sentiment and intention can be modeled as the user belief and solved by maximizing the information bottleneck. By this user belief modeling, we apply the model-based reinforcement learning framework to the dialogue system, and propose a framework called DreamCUB. Experiments show that the pretrained dialogue world model can achieve state-of-the-art performances on emotion classification and sentiment identification, while dialogue quality is also enhanced by joint training of the policy, critic and dialogue world model. Further analysis shows that this manner holds a reasonable exploration-exploitation balance and also transfers well to out-of-domain scenarios such as empathetic dialogues.

DiffOSeg: Omni Medical Image Segmentation via Multi-Expert Collaboration Diffusion Model

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation predictions often fail to capture these annotator biases. Although recent studies have explored multi-rater segmentation, existing methods typically focus on a single perspective -- either generating a probabilistic ``gold standard'' consensus or preserving expert-specific preferences -- thus struggling to provide a more omni view. In this study, we propose DiffOSeg, a two-stage diffusion-based framework, which aims to simultaneously achieve both consensus-driven (combining all experts' opinions) and preference-driven (reflecting experts' individual assessments) segmentation. Stage I establishes population consensus through a probabilistic consensus strategy, while Stage II captures expert-specific preference via adaptive prompts. Demonstrated on two public datasets (LIDC-IDRI and NPC-170), our model outperforms existing state-of-the-art methods across all evaluated metrics. Source code is available at https://github.com/string-ellipses/DiffOSeg .

SAFER: A Calibrated Risk-Aware Multimodal Recommendation Model for Dynamic Treatment Regimes

Dynamic treatment regimes (DTRs) are critical to precision medicine, optimizing long-term outcomes through personalized, real-time decision-making in evolving clinical contexts, but require careful supervision for unsafe treatment risks. Existing efforts rely primarily on clinician-prescribed gold standards despite the absence of a known optimal strategy, and predominantly using structured EHR data without extracting valuable insights from clinical notes, limiting their reliability for treatment recommendations. In this work, we introduce SAFER, a calibrated risk-aware tabular-language recommendation framework for DTR that integrates both structured EHR and clinical notes, enabling them to learn from each other, and addresses inherent label uncertainty by assuming ambiguous optimal treatment solution for deceased patients. Moreover, SAFER employs conformal prediction to provide statistical guarantees, ensuring safe treatment recommendations while filtering out uncertain predictions. Experiments on two publicly available sepsis datasets demonstrate that SAFER outperforms state-of-the-art baselines across multiple recommendation metrics and counterfactual mortality rate, while offering robust formal assurances. These findings underscore SAFER potential as a trustworthy and theoretically grounded solution for high-stakes DTR applications.

FreeTimeGS: Free Gaussian Primitives at Anytime and Anywhere for Dynamic Scene Reconstruction

This paper addresses the challenge of reconstructing dynamic 3D scenes with complex motions. Some recent works define 3D Gaussian primitives in the canonical space and use deformation fields to map canonical primitives to observation spaces, achieving real-time dynamic view synthesis. However, these methods often struggle to handle scenes with complex motions due to the difficulty of optimizing deformation fields. To overcome this problem, we propose FreeTimeGS, a novel 4D representation that allows Gaussian primitives to appear at arbitrary time and locations. In contrast to canonical Gaussian primitives, our representation possesses the strong flexibility, thus improving the ability to model dynamic 3D scenes. In addition, we endow each Gaussian primitive with an motion function, allowing it to move to neighboring regions over time, which reduces the temporal redundancy. Experiments results on several datasets show that the rendering quality of our method outperforms recent methods by a large margin. Project page: https://zju3dv.github.io/freetimegs/ .

Challenger: Affordable Adversarial Driving Video Generation

Generating photorealistic driving videos has seen significant progress recently, but current methods largely focus on ordinary, non-adversarial scenarios. Meanwhile, efforts to generate adversarial driving scenarios often operate on abstract trajectory or BEV representations, falling short of delivering realistic sensor data that can truly stress-test autonomous driving (AD) systems. In this work, we introduce Challenger, a framework that produces physically plausible yet photorealistic adversarial driving videos. Generating such videos poses a fundamental challenge: it requires jointly optimizing over the space of traffic interactions and high-fidelity sensor observations. Challenger makes this affordable through two techniques: (1) a physics-aware multi-round trajectory refinement process that narrows down candidate adversarial maneuvers, and (2) a tailored trajectory scoring function that encourages realistic yet adversarial behavior while maintaining compatibility with downstream video synthesis. As tested on the nuScenes dataset, Challenger generates a diverse range of aggressive driving scenarios-including cut-ins, sudden lane changes, tailgating, and blind spot intrusions-and renders them into multiview photorealistic videos. Extensive evaluations show that these scenarios significantly increase the collision rate of state-of-the-art end-to-end AD models (UniAD, VAD, SparseDrive, and DiffusionDrive), and importantly, adversarial behaviors discovered for one model often transfer to others.

Sage Deer: A Super-Aligned Driving Generalist Is Your Copilot

The intelligent driving cockpit, an important part of intelligent driving, needs to match different users' comfort, interaction, and safety needs. This paper aims to build a Super-Aligned and GEneralist DRiving agent, SAGE DeeR. Sage Deer achieves three highlights: (1) Super alignment: It achieves different reactions according to different people's preferences and biases. (2) Generalist: It can understand the multi-view and multi-mode inputs to reason the user's physiological indicators, facial emotions, hand movements, body movements, driving scenarios, and behavioral decisions. (3) Self-Eliciting: It can elicit implicit thought chains in the language space to further increase generalist and super-aligned abilities. Besides, we collected multiple data sets and built a large-scale benchmark. This benchmark measures the deer's perceptual decision-making ability and the super alignment's accuracy.

Convert Language Model into a Value-based Strategic Planner

Emotional support conversation (ESC) aims to alleviate the emotional distress of individuals through effective conversations. Although large language models (LLMs) have obtained remarkable progress on ESC, most of these studies might not define the diagram from the state model perspective, therefore providing a suboptimal solution for long-term satisfaction. To address such an issue, we leverage the Q-learning on LLMs, and propose a framework called straQ*. Our framework allows a plug-and-play LLM to bootstrap the planning during ESC, determine the optimal strategy based on long-term returns, and finally guide the LLM to response. Substantial experiments on ESC datasets suggest that straQ* outperforms many baselines, including direct inference, self-refine, chain of thought, finetuning, and finite state machines.

FiSMiness: A Finite State Machine Based Paradigm for Emotional Support Conversations

Emotional support conversation (ESC) aims to alleviate the emotional distress of individuals through effective conversations. Although large language models (LLMs) have obtained remarkable progress on ESC, most of these studies might not define the diagram from the state model perspective, therefore providing a suboptimal solution for long-term satisfaction. To address such an issue, we leverage the Finite State Machine (FSM) on LLMs, and propose a framework called FiSMiness. Our framework allows a single LLM to bootstrap the planning during ESC, and self-reason the seeker's emotion, support strategy and the final response upon each conversational turn. Substantial experiments on ESC datasets suggest that FiSMiness outperforms many baselines, including direct inference, self-refine, chain of thought, finetuning, and external-assisted methods, even those with many more parameters.