Cross-Modality Masked Learning for Survival Prediction in ICI Treated NSCLC Patients

Accurate prognosis of non-small cell lung cancer (NSCLC) patients undergoing immunotherapy is essential for personalized treatment planning, enabling informed patient decisions, and improving both treatment outcomes and quality of life. However, the lack of large, relevant datasets and effective multi-modal feature fusion strategies pose significant challenges in this domain. To address these challenges, we present a large-scale dataset and introduce a novel framework for multi-modal feature fusion aimed at enhancing the accuracy of survival prediction. The dataset comprises 3D CT images and corresponding clinical records from NSCLC patients treated with immune checkpoint inhibitors (ICI), along with progression-free survival (PFS) and overall survival (OS) data. We further propose a cross-modality masked learning approach for medical feature fusion, consisting of two distinct branches, each tailored to its respective modality: a Slice-Depth Transformer for extracting 3D features from CT images and a graph-based Transformer for learning node features and relationships among clinical variables in tabular data. The fusion process is guided by a masked modality learning strategy, wherein the model utilizes the intact modality to reconstruct missing components. This mechanism improves the integration of modality-specific features, fostering more effective inter-modality relationships and feature interactions. Our approach demonstrates superior performance in multi-modal integration for NSCLC survival prediction, surpassing existing methods and setting a new benchmark for prognostic models in this context.

MCA-RG: Enhancing LLMs with Medical Concept Alignment for Radiology Report Generation

Despite significant advancements in adapting Large Language Models (LLMs) for radiology report generation (RRG), clinical adoption remains challenging due to difficulties in accurately mapping pathological and anatomical features to their corresponding text descriptions. Additionally, semantic agnostic feature extraction further hampers the generation of accurate diagnostic reports. To address these challenges, we introduce Medical Concept Aligned Radiology Report Generation (MCA-RG), a knowledge-driven framework that explicitly aligns visual features with distinct medical concepts to enhance the report generation process. MCA-RG utilizes two curated concept banks: a pathology bank containing lesion-related knowledge, and an anatomy bank with anatomical descriptions. The visual features are aligned with these medical concepts and undergo tailored enhancement. We further propose an anatomy-based contrastive learning procedure to improve the generalization of anatomical features, coupled with a matching loss for pathological features to prioritize clinically relevant regions. Additionally, a feature gating mechanism is employed to filter out low-quality concept features. Finally, the visual features are corresponding to individual medical concepts, and are leveraged to guide the report generation process. Experiments on two public benchmarks (MIMIC-CXR and CheXpert Plus) demonstrate that MCA-RG achieves superior performance, highlighting its effectiveness in radiology report generation.

MVP: Winning Solution to SMP Challenge 2025 Video Track

Social media platforms serve as central hubs for content dissemination, opinion expression, and public engagement across diverse modalities. Accurately predicting the popularity of social media videos enables valuable applications in content recommendation, trend detection, and audience engagement. In this paper, we present Multimodal Video Predictor (MVP), our winning solution to the Video Track of the SMP Challenge 2025. MVP constructs expressive post representations by integrating deep video features extracted from pretrained models with user metadata and contextual information. The framework applies systematic preprocessing techniques, including log-transformations and outlier removal, to improve model robustness. A gradient-boosted regression model is trained to capture complex patterns across modalities. Our approach ranked first in the official evaluation of the Video Track, demonstrating its effectiveness and reliability for multimodal video popularity prediction on social platforms. The source code is available at https://anonymous.4open.science/r/SMPDVideo.

HyperFusion: Hierarchical Multimodal Ensemble Learning for Social Media Popularity Prediction

Social media popularity prediction plays a crucial role in content optimization, marketing strategies, and user engagement enhancement across digital platforms. However, predicting post popularity remains challenging due to the complex interplay between visual, textual, temporal, and user behavioral factors. This paper presents HyperFusion, a hierarchical multimodal ensemble learning framework for social media popularity prediction. Our approach employs a three-tier fusion architecture that progressively integrates features across abstraction levels: visual representations from CLIP encoders, textual embeddings from transformer models, and temporal-spatial metadata with user characteristics. The framework implements a hierarchical ensemble strategy combining CatBoost, TabNet, and custom multi-layer perceptrons. To address limited labeled data, we propose a two-stage training methodology with pseudo-labeling and iterative refinement. We introduce novel cross-modal similarity measures and hierarchical clustering features that capture inter-modal dependencies. Experimental results demonstrate that HyperFusion achieves competitive performance on the SMP challenge dataset. Our team achieved third place in the SMP Challenge 2025 (Image Track). The source code is available at https://anonymous.4open.science/r/SMPDImage.

Towards an Introspective Dynamic Model of Globally Distributed Computing Infrastructures

Large-scale scientific collaborations like ATLAS, Belle II, CMS, DUNE, and others involve hundreds of research institutes and thousands of researchers spread across the globe. These experiments generate petabytes of data, with volumes soon expected to reach exabytes. Consequently, there is a growing need for computation, including structured data processing from raw data to consumer-ready derived data, extensive Monte Carlo simulation campaigns, and a wide range of end-user analysis. To manage these computational and storage demands, centralized workflow and data management systems are implemented. However, decisions regarding data placement and payload allocation are often made disjointly and via heuristic means. A significant obstacle in adopting more effective heuristic or AI-driven solutions is the absence of a quick and reliable introspective dynamic model to evaluate and refine alternative approaches. In this study, we aim to develop such an interactive system using real-world data. By examining job execution records from the PanDA workflow management system, we have pinpointed key performance indicators such as queuing time, error rate, and the extent of remote data access. The dataset includes five months of activity. Additionally, we are creating a generative AI model to simulate time series of payloads, which incorporate visible features like category, event count, and submitting group, as well as hidden features like the total computational load-derived from existing PanDA records and computing site capabilities. These hidden features, which are not visible to job allocators, whether heuristic or AI-driven, influence factors such as queuing times and data movement.

Efficiency Robustness of Dynamic Deep Learning Systems

Deep Learning Systems (DLSs) are increasingly deployed in real-time applications, including those in resourceconstrained environments such as mobile and IoT devices. To address efficiency challenges, Dynamic Deep Learning Systems (DDLSs) adapt inference computation based on input complexity, reducing overhead. While this dynamic behavior improves efficiency, such behavior introduces new attack surfaces. In particular, efficiency adversarial attacks exploit these dynamic mechanisms to degrade system performance. This paper systematically explores efficiency robustness of DDLSs, presenting the first comprehensive taxonomy of efficiency attacks. We categorize these attacks based on three dynamic behaviors: (i) attacks on dynamic computations per inference, (ii) attacks on dynamic inference iterations, and (iii) attacks on dynamic output production for downstream tasks. Through an in-depth evaluation, we analyze adversarial strategies that target DDLSs efficiency and identify key challenges in securing these systems. In addition, we investigate existing defense mechanisms, demonstrating their limitations against increasingly popular efficiency attacks and the necessity for novel mitigation strategies to secure future adaptive DDLSs.

Hierarchical Tree Search-based User Lifelong Behavior Modeling on Large Language Model

Large Language Models (LLMs) have garnered significant attention in Recommendation Systems (RS) due to their extensive world knowledge and robust reasoning capabilities. However, a critical challenge lies in enabling LLMs to effectively comprehend and extract insights from massive user behaviors. Current approaches that directly leverage LLMs for user interest learning face limitations in handling long sequential behaviors, effectively extracting interest, and applying interest in practical scenarios. To address these issues, we propose a Hierarchical Tree Search-based User Lifelong Behavior Modeling framework (HiT-LBM). HiT-LBM integrates Chunked User Behavior Extraction (CUBE) and Hierarchical Tree Search for Interest (HTS) to capture diverse interests and interest evolution of user. CUBE divides user lifelong behaviors into multiple chunks and learns the interest and interest evolution within each chunk in a cascading manner. HTS generates candidate interests through hierarchical expansion and searches for the optimal interest with process rating model to ensure information gain for each behavior chunk. Additionally, we design Temporal-Ware Interest Fusion (TIF) to integrate interests from multiple behavior chunks, constructing a comprehensive representation of user lifelong interests. The representation can be embedded into any recommendation model to enhance performance. Extensive experiments demonstrate the effectiveness of our approach, showing that it surpasses state-of-the-art methods.

HIT Model: A Hierarchical Interaction-Enhanced Two-Tower Model for Pre-Ranking Systems

Online display advertising platforms rely on pre-ranking systems to efficiently filter and prioritize candidate ads from large corpora, balancing relevance to users with strict computational constraints. The prevailing two-tower architecture, though highly efficient due to its decoupled design and pre-caching, suffers from cross-domain interaction and coarse similarity metrics, undermining its capacity to model complex user-ad relationships. In this study, we propose the Hierarchical Interaction-Enhanced Two-Tower (HIT) model, a new architecture that augments the two-tower paradigm with two key components: $\textit{generators}$ that pre-generate holistic vectors incorporating coarse-grained user-ad interactions through a dual-generator framework with a cosine-similarity-based generation loss as the training objective, and $\textit{multi-head representers}$ that project embeddings into multiple latent subspaces to capture fine-grained, multi-faceted user interests and multi-dimensional ad attributes. This design enhances modeling effectiveness without compromising inference efficiency. Extensive experiments on public datasets and large-scale online A/B testing on Tencent's advertising platform demonstrate that HIT significantly outperforms several baselines in relevance metrics, yielding a $1.66\%$ increase in Gross Merchandise Volume and a $1.55\%$ improvement in Return on Investment, alongside similar serving latency to the vanilla two-tower models. The HIT model has been successfully deployed in Tencent's online display advertising system, serving billions of impressions daily. The code is available at https://anonymous.4open.science/r/HIT_model-5C23.

OMGM: Orchestrate Multiple Granularities and Modalities for Efficient Multimodal Retrieval

Vision-language retrieval-augmented generation (RAG) has become an effective approach for tackling Knowledge-Based Visual Question Answering (KB-VQA), which requires external knowledge beyond the visual content presented in images. The effectiveness of Vision-language RAG systems hinges on multimodal retrieval, which is inherently challenging due to the diverse modalities and knowledge granularities in both queries and knowledge bases. Existing methods have not fully tapped into the potential interplay between these elements. We propose a multimodal RAG system featuring a coarse-to-fine, multi-step retrieval that harmonizes multiple granularities and modalities to enhance efficacy. Our system begins with a broad initial search aligning knowledge granularity for cross-modal retrieval, followed by a multimodal fusion reranking to capture the nuanced multimodal information for top entity selection. A text reranker then filters out the most relevant fine-grained section for augmented generation. Extensive experiments on the InfoSeek and Encyclopedic-VQA benchmarks show our method achieves state-of-the-art retrieval performance and highly competitive answering results, underscoring its effectiveness in advancing KB-VQA systems.

PrimitiveAnything: Human-Crafted 3D Primitive Assembly Generation with Auto-Regressive Transformer

Shape primitive abstraction, which decomposes complex 3D shapes into simple geometric elements, plays a crucial role in human visual cognition and has broad applications in computer vision and graphics. While recent advances in 3D content generation have shown remarkable progress, existing primitive abstraction methods either rely on geometric optimization with limited semantic understanding or learn from small-scale, category-specific datasets, struggling to generalize across diverse shape categories. We present PrimitiveAnything, a novel framework that reformulates shape primitive abstraction as a primitive assembly generation task. PrimitiveAnything includes a shape-conditioned primitive transformer for auto-regressive generation and an ambiguity-free parameterization scheme to represent multiple types of primitives in a unified manner. The proposed framework directly learns the process of primitive assembly from large-scale human-crafted abstractions, enabling it to capture how humans decompose complex shapes into primitive elements. Through extensive experiments, we demonstrate that PrimitiveAnything can generate high-quality primitive assemblies that better align with human perception while maintaining geometric fidelity across diverse shape categories. It benefits various 3D applications and shows potential for enabling primitive-based user-generated content (UGC) in games. Project page: https://primitiveanything.github.io