MedDM:LLM-executable clinical guidance tree for clinical decision-making

It is becoming increasingly emphasis on the importance of LLM participating in clinical diagnosis decision-making. However, the low specialization refers to that current medical LLMs can not provide specific medical advice, which are more like a medical Q\&A. And there is no suitable clinical guidance tree data set that can be used directly with LLM. To address this issue, we first propose LLM-executavle clinical guidance tree(CGT), which can be directly used by large language models, and construct medical diagnostic decision-making dataset (MedDM), from flowcharts in clinical practice guidelines. We propose an approach to screen flowcharts from medical literature, followed by their identification and conversion into standardized diagnostic decision trees. Constructed a knowledge base with 1202 decision trees, which came from 5000 medical literature and covered 12 hospital departments, including internal medicine, surgery, psychiatry, and over 500 diseases.Moreover, we propose a method for reasoning on LLM-executable CGT and a Patient-LLM multi-turn dialogue framework.

Prompt-augmented Temporal Point Process for Streaming Event Sequence

Neural Temporal Point Processes (TPPs) are the prevalent paradigm for modeling continuous-time event sequences, such as user activities on the web and financial transactions. In real-world applications, event data is typically received in a \emph{streaming} manner, where the distribution of patterns may shift over time. Additionally, \emph{privacy and memory constraints} are commonly observed in practical scenarios, further compounding the challenges. Therefore, the continuous monitoring of a TPP to learn the streaming event sequence is an important yet under-explored problem. Our work paper addresses this challenge by adopting Continual Learning (CL), which makes the model capable of continuously learning a sequence of tasks without catastrophic forgetting under realistic constraints. Correspondingly, we propose a simple yet effective framework, PromptTPP\footnote{Our code is available at {\small \url{ https://github.com/yanyanSann/PromptTPP}}}, by integrating the base TPP with a continuous-time retrieval prompt pool. The prompts, small learnable parameters, are stored in a memory space and jointly optimized with the base TPP, ensuring that the model learns event streams sequentially without buffering past examples or task-specific attributes. We present a novel and realistic experimental setup for modeling event streams, where PromptTPP consistently achieves state-of-the-art performance across three real user behavior datasets.

Time-LLM: Time Series Forecasting by Reprogramming Large Language Models

Time series forecasting holds significant importance in many real-world dynamic systems and has been extensively studied. Unlike natural language process (NLP) and computer vision (CV), where a single large model can tackle multiple tasks, models for time series forecasting are often specialized, necessitating distinct designs for different tasks and applications. While pre-trained foundation models have made impressive strides in NLP and CV, their development in time series domains has been constrained by data sparsity. Recent studies have revealed that large language models (LLMs) possess robust pattern recognition and reasoning abilities over complex sequences of tokens. However, the challenge remains in effectively aligning the modalities of time series data and natural language to leverage these capabilities. In this work, we present Time-LLM, a reprogramming framework to repurpose LLMs for general time series forecasting with the backbone language models kept intact. We begin by reprogramming the input time series with text prototypes before feeding it into the frozen LLM to align the two modalities. To augment the LLM's ability to reason with time series data, we propose Prompt-as-Prefix (PaP), which enriches the input context and directs the transformation of reprogrammed input patches. The transformed time series patches from the LLM are finally projected to obtain the forecasts. Our comprehensive evaluations demonstrate that Time-LLM is a powerful time series learner that outperforms state-of-the-art, specialized forecasting models. Moreover, Time-LLM excels in both few-shot and zero-shot learning scenarios.

LLM-Mini-CEX: Automatic Evaluation of Large Language Model for Diagnostic Conversation

There is an increasing interest in developing LLMs for medical diagnosis to improve diagnosis efficiency. Despite their alluring technological potential, there is no unified and comprehensive evaluation criterion, leading to the inability to evaluate the quality and potential risks of medical LLMs, further hindering the application of LLMs in medical treatment scenarios. Besides, current evaluations heavily rely on labor-intensive interactions with LLMs to obtain diagnostic dialogues and human evaluation on the quality of diagnosis dialogue. To tackle the lack of unified and comprehensive evaluation criterion, we first initially establish an evaluation criterion, termed LLM-specific Mini-CEX to assess the diagnostic capabilities of LLMs effectively, based on original Mini-CEX. To address the labor-intensive interaction problem, we develop a patient simulator to engage in automatic conversations with LLMs, and utilize ChatGPT for evaluating diagnosis dialogues automatically. Experimental results show that the LLM-specific Mini-CEX is adequate and necessary to evaluate medical diagnosis dialogue. Besides, ChatGPT can replace manual evaluation on the metrics of humanistic qualities and provides reproducible and automated comparisons between different LLMs.

EasyTPP: Towards Open Benchmarking the Temporal Point Processes

Continuous-time event sequences play a vital role in real-world domains such as healthcare, finance, online shopping, social networks, and so on. To model such data, temporal point processes (TPPs) have emerged as the most advanced generative models, making a significant impact in both academic and application communities. Despite the emergence of many powerful models in recent years, there is still no comprehensive benchmark to evaluate them. This lack of standardization impedes researchers and practitioners from comparing methods and reproducing results, potentially slowing down progress in this field. In this paper, we present EasyTPP, which aims to establish a central benchmark for evaluating TPPs. Compared to previous work that also contributed datasets, our EasyTPP has three unique contributions to the community: (i) a comprehensive implementation of eight highly cited neural TPPs with the integration of commonly used evaluation metrics and datasets; (ii) a standardized benchmarking pipeline for a transparent and thorough comparison of different methods on different datasets; (iii) a universal framework supporting multiple ML libraries (e.g., PyTorch and TensorFlow) as well as custom implementations. Our benchmark is open-sourced: all the data and implementation can be found at this \href{https://github.com/ant-research/EasyTemporalPointProcess}{\textcolor{blue}{Github repository}}\footnote{\url{https://github.com/ant-research/EasyTemporalPointProcess}.}. We will actively maintain this benchmark and welcome contributions from other researchers and practitioners. Our benchmark will help promote reproducible research in this field, thus accelerating research progress as well as making more significant real-world impacts.

MidMed: Towards Mixed-Type Dialogues for Medical Consultation

Most medical dialogue systems assume that patients have clear goals (medicine querying, surgical operation querying, etc.) before medical consultation. However, in many real scenarios, due to the lack of medical knowledge, it is usually difficult for patients to determine clear goals with all necessary slots. In this paper, we identify this challenge as how to construct medical consultation dialogue systems to help patients clarify their goals. To mitigate this challenge, we propose a novel task and create a human-to-human mixed-type medical consultation dialogue corpus, termed MidMed, covering five dialogue types: task-oriented dialogue for diagnosis, recommendation, knowledge-grounded dialogue, QA, and chitchat. MidMed covers four departments (otorhinolaryngology, ophthalmology, skin, and digestive system), with 8,175 dialogues. Furthermore, we build baselines on MidMed and propose an instruction-guiding medical dialogue generation framework, termed InsMed, to address this task. Experimental results show the effectiveness of InsMed.

Language Models Can Improve Event Prediction by Few-Shot Abductive Reasoning

Large language models have shown astonishing performance on a wide range of reasoning tasks. In this paper, we investigate whether they could reason about real-world events and help improve the prediction accuracy of event sequence models. We design a modeling and prediction framework where a large language model performs abductive reasoning to assist an event sequence model: the event model proposes predictions on future events given the past; instructed by a few expert-annotated demonstrations, the language model learns to suggest possible causes for each proposal; a search module finds out the previous events that match the causes; a scoring function learns to examine whether the retrieved events could actually cause the proposal. Through extensive experiments on two challenging real-world datasets (Amazon Review and GDELT), we demonstrate that our framework -- thanks to the reasoning ability of language models -- could significantly outperform the state-of-the-art event sequence models.

MedGPTEval: A Dataset and Benchmark to Evaluate Responses of Large Language Models in Medicine

METHODS: First, a set of evaluation criteria is designed based on a comprehensive literature review. Second, existing candidate criteria are optimized for using a Delphi method by five experts in medicine and engineering. Third, three clinical experts design a set of medical datasets to interact with LLMs. Finally, benchmarking experiments are conducted on the datasets. The responses generated by chatbots based on LLMs are recorded for blind evaluations by five licensed medical experts. RESULTS: The obtained evaluation criteria cover medical professional capabilities, social comprehensive capabilities, contextual capabilities, and computational robustness, with sixteen detailed indicators. The medical datasets include twenty-seven medical dialogues and seven case reports in Chinese. Three chatbots are evaluated, ChatGPT by OpenAI, ERNIE Bot by Baidu Inc., and Doctor PuJiang (Dr. PJ) by Shanghai Artificial Intelligence Laboratory. Experimental results show that Dr. PJ outperforms ChatGPT and ERNIE Bot in both multiple-turn medical dialogue and case report scenarios.

Full Scaling Automation for Sustainable Development of Green Data Centers

The rapid rise in cloud computing has resulted in an alarming increase in data centers' carbon emissions, which now accounts for >3% of global greenhouse gas emissions, necessitating immediate steps to combat their mounting strain on the global climate. An important focus of this effort is to improve resource utilization in order to save electricity usage. Our proposed Full Scaling Automation (FSA) mechanism is an effective method of dynamically adapting resources to accommodate changing workloads in large-scale cloud computing clusters, enabling the clusters in data centers to maintain their desired CPU utilization target and thus improve energy efficiency. FSA harnesses the power of deep representation learning to accurately predict the future workload of each service and automatically stabilize the corresponding target CPU usage level, unlike the previous autoscaling methods, such as Autopilot or FIRM, that need to adjust computing resources with statistical models and expert knowledge. Our approach achieves significant performance improvement compared to the existing work in real-world datasets. We also deployed FSA on large-scale cloud computing clusters in industrial data centers, and according to the certification of the China Environmental United Certification Center (CEC), a reduction of 947 tons of carbon dioxide, equivalent to a saving of 1538,000 kWh of electricity, was achieved during the Double 11 shopping festival of 2022, marking a critical step for our company's strategic goal towards carbon neutrality by 2030.