ChatRadio-Valuer: A Chat Large Language Model for Generalizable Radiology Report Generation Based on Multi-institution and Multi-system Data

Radiology report generation, as a key step in medical image analysis, is critical to the quantitative analysis of clinically informed decision-making levels. However, complex and diverse radiology reports with cross-source heterogeneity pose a huge generalizability challenge to the current methods under massive data volume, mainly because the style and normativity of radiology reports are obviously distinctive among institutions, body regions inspected and radiologists. Recently, the advent of large language models (LLM) offers great potential for recognizing signs of health conditions. To resolve the above problem, we collaborate with the Second Xiangya Hospital in China and propose ChatRadio-Valuer based on the LLM, a tailored model for automatic radiology report generation that learns generalizable representations and provides a basis pattern for model adaptation in sophisticated analysts' cases. Specifically, ChatRadio-Valuer is trained based on the radiology reports from a single institution by means of supervised fine-tuning, and then adapted to disease diagnosis tasks for human multi-system evaluation (i.e., chest, abdomen, muscle-skeleton, head, and maxillofacial $\&$ neck) from six different institutions in clinical-level events. The clinical dataset utilized in this study encompasses a remarkable total of \textbf{332,673} observations. From the comprehensive results on engineering indicators, clinical efficacy and deployment cost metrics, it can be shown that ChatRadio-Valuer consistently outperforms state-of-the-art models, especially ChatGPT (GPT-3.5-Turbo) and GPT-4 et al., in terms of the diseases diagnosis from radiology reports. ChatRadio-Valuer provides an effective avenue to boost model generalization performance and alleviate the annotation workload of experts to enable the promotion of clinical AI applications in radiology reports.

Uncertainty Quantification in Inverse Models in Hydrology

In hydrology, modeling streamflow remains a challenging task due to the limited availability of basin characteristics information such as soil geology and geomorphology. These characteristics may be noisy due to measurement errors or may be missing altogether. To overcome this challenge, we propose a knowledge-guided, probabilistic inverse modeling method for recovering physical characteristics from streamflow and weather data, which are more readily available. We compare our framework with state-of-the-art inverse models for estimating river basin characteristics. We also show that these estimates offer improvement in streamflow modeling as opposed to using the original basin characteristic values. Our inverse model offers 3\% improvement in R$^2$ for the inverse model (basin characteristic estimation) and 6\% for the forward model (streamflow prediction). Our framework also offers improved explainability since it can quantify uncertainty in both the inverse and the forward model. Uncertainty quantification plays a pivotal role in improving the explainability of machine learning models by providing additional insights into the reliability and limitations of model predictions. In our analysis, we assess the quality of the uncertainty estimates. Compared to baseline uncertainty quantification methods, our framework offers 10\% improvement in the dispersion of epistemic uncertainty and 13\% improvement in coverage rate. This information can help stakeholders understand the level of uncertainty associated with the predictions and provide a more comprehensive view of the potential outcomes.

Completing Visual Objects via Bridging Generation and Segmentation

This paper presents a novel approach to object completion, with the primary goal of reconstructing a complete object from its partially visible components. Our method, named MaskComp, delineates the completion process through iterative stages of generation and segmentation. In each iteration, the object mask is provided as an additional condition to boost image generation, and, in return, the generated images can lead to a more accurate mask by fusing the segmentation of images. We demonstrate that the combination of one generation and one segmentation stage effectively functions as a mask denoiser. Through alternation between the generation and segmentation stages, the partial object mask is progressively refined, providing precise shape guidance and yielding superior object completion results. Our experiments demonstrate the superiority of MaskComp over existing approaches, e.g., ControlNet and Stable Diffusion, establishing it as an effective solution for object completion.

Corex: Pushing the Boundaries of Complex Reasoning through Multi-Model Collaboration

Large Language Models (LLMs) are evolving at an unprecedented pace and have exhibited considerable capability in the realm of natural language processing (NLP) with world knowledge. Benefiting from ultra-large-scale training corpora, a single LLM can manage typical NLP tasks competently. However, its performance in executing reasoning tasks is still confined by the limitations of its internal representations. To push this boundary further, we introduce Corex in this paper, a suite of novel general-purpose strategies that transform LLMs into autonomous agents pioneering multi-model collaborations for complex task-solving. Inspired by human behaviors, Corex is constituted by diverse collaboration paradigms including Debate, Review, and Retrieve modes, which collectively work towards enhancing the factuality, faithfulness, and reliability of the reasoning process. These paradigms foster task-agnostic approaches that enable LLMs to ''think outside the box,'' thereby overcoming hallucinations and providing better solutions. Through extensive experiments across four different types of reasoning tasks, we demonstrate that orchestrating multiple LLMs to work in concert yields substantially better performance compared to existing methods. Further results and in-depth analysis demonstrate the cost-effectiveness of our method, facilitating collaboration among different LLMs and promoting annotation efficiency.

Rethinking Audiovisual Segmentation with Semantic Quantization and Decomposition

Audiovisual segmentation (AVS) is a challenging task that aims to segment visual objects in videos based on their associated acoustic cues. With multiple sound sources involved, establishing robust correspondences between audio and visual contents poses unique challenges due to its (1) intricate entanglement across sound sources and (2) frequent shift among sound events. Assuming sound events occur independently, the multi-source semantic space (which encompasses all possible semantic categories) can be viewed as the Cartesian product of single-source sub-spaces. This motivates us to decompose the multi-source audio semantics into single-source semantics, allowing for more effective interaction with visual content. Specifically, we propose a semantic decomposition method based on product quantization, where the multi-source semantics can be decomposed and represented by several quantized single-source semantics. Furthermore, we introduce a global-to-local quantization mechanism that distills knowledge from stable global (clip-level) features into local (frame-level) ones to handle the constant shift of audio semantics. Extensive experiments demonstrate that semantically quantized and decomposed audio representation significantly improves AVS performance, e.g., +21.2% mIoU on the most challenging AVS-Semantic benchmark.

Generating Personalized Insulin Treatments Strategies with Deep Conditional Generative Time Series Models

We propose a novel framework that combines deep generative time series models with decision theory for generating personalized treatment strategies. It leverages historical patient trajectory data to jointly learn the generation of realistic personalized treatment and future outcome trajectories through deep generative time series models. In particular, our framework enables the generation of novel multivariate treatment strategies tailored to the personalized patient history and trained for optimal expected future outcomes based on conditional expected utility maximization. We demonstrate our framework by generating personalized insulin treatment strategies and blood glucose predictions for hospitalized diabetes patients, showcasing the potential of our approach for generating improved personalized treatment strategies. Keywords: deep generative model, probabilistic decision support, personalized treatment generation, insulin and blood glucose prediction

MedEdit: Model Editing for Medical Question Answering with External Knowledge Bases

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks like medical question answering (QA). Moreover, they tend to function as "black-boxes," making it challenging to modify their behavior. Addressing this, our study delves into model editing utilizing in-context learning, aiming to improve LLM responses without the need for fine-tuning or retraining. Specifically, we propose a comprehensive retrieval strategy to extract medical facts from an external knowledge base, and then we incorporate them into the query prompt for the LLM. Focusing on medical QA using the MedQA-SMILE dataset, we evaluate the impact of different retrieval models and the number of facts provided to the LLM. Notably, our edited Vicuna model exhibited an accuracy improvement from 44.46% to 48.54%. This work underscores the potential of model editing to enhance LLM performance, offering a practical approach to mitigate the challenges of black-box LLMs.

In-Hand Re-grasp Manipulation with Passive Dynamic Actions via Imitation Learning

Re-grasp manipulation leverages on ergonomic tools to assist humans in accomplishing diverse tasks. In certain scenarios, humans often employ external forces to effortlessly and precisely re-grasp tools like a hammer. Previous development on controllers for in-grasp sliding motion using passive dynamic actions (e.g.,gravity) relies on apprehension of finger-object contact information, and requires customized design for individual objects with varied geometry and weight distribution. It limits their adaptability to diverse objects. In this paper, we propose an end-to-end sliding motion controller based on imitation learning (IL) that necessitates minimal prior knowledge of object mechanics, relying solely on object position information. To expedite training convergence, we utilize a data glove to collect expert data trajectories and train the policy through Generative Adversarial Imitation Learning (GAIL). Simulation results demonstrate the controller's versatility in performing in-hand sliding tasks with objects of varying friction coefficients, geometric shapes, and masses. By migrating to a physical system using visual position estimation, the controller demonstrated an average success rate of 86%, surpassing the baseline algorithm's success rate of 35% of Behavior Cloning(BC) and 20% of Proximal Policy Optimization (PPO).

Learning to Assist Different Wearers in Multitasks: Efficient and Individualized Human-In-the-Loop Adaption Framework for Exoskeleton Robots

One of the typical purposes of using lower-limb exoskeleton robots is to provide assistance to the wearer by supporting their weight and augmenting their physical capabilities according to a given task and human motion intentions. The generalizability of robots across different wearers in multiple tasks is important to ensure that the robot can provide correct and effective assistance in actual implementation. However, most lower-limb exoskeleton robots exhibit only limited generalizability. Therefore, this paper proposes a human-in-the-loop learning and adaptation framework for exoskeleton robots to improve their performance in various tasks and for different wearers. To suit different wearers, an individualized walking trajectory is generated online using dynamic movement primitives and Bayes optimization. To accommodate various tasks, a task translator is constructed using a neural network to generalize a trajectory to more complex scenarios. These generalization techniques are integrated into a unified variable impedance model, which regulates the exoskeleton to provide assistance while ensuring safety. In addition, an anomaly detection network is developed to quantitatively evaluate the wearer's comfort, which is considered in the trajectory learning procedure and contributes to the relaxation of conflicts in impedance control. The proposed framework is easy to implement, because it requires proprioceptive sensors only to perform and deploy data-efficient learning schemes. This makes the exoskeleton practical for deployment in complex scenarios, accommodating different walking patterns, habits, tasks, and conflicts. Experiments and comparative studies on a lower-limb exoskeleton robot are performed to demonstrate the effectiveness of the proposed framework.

AutoPrep: An Automatic Preprocessing Framework for In-the-Wild Speech Data

Recently, the utilization of extensive open-sourced text data has significantly advanced the performance of text-based large language models (LLMs). However, the use of in-the-wild large-scale speech data in the speech technology community remains constrained. One reason for this limitation is that a considerable amount of the publicly available speech data is compromised by background noise, speech overlapping, lack of speech segmentation information, missing speaker labels, and incomplete transcriptions, which can largely hinder their usefulness. On the other hand, human annotation of speech data is both time-consuming and costly. To address this issue, we introduce an automatic in-the-wild speech data preprocessing framework (AutoPrep) in this paper, which is designed to enhance speech quality, generate speaker labels, and produce transcriptions automatically. The proposed AutoPrep framework comprises six components: speech enhancement, speech segmentation, speaker clustering, target speech extraction, quality filtering and automatic speech recognition. Experiments conducted on the open-sourced WenetSpeech and our self-collected AutoPrepWild corpora demonstrate that the proposed AutoPrep framework can generate preprocessed data with similar DNSMOS and PDNSMOS scores compared to several open-sourced TTS datasets. The corresponding TTS system can achieve up to 0.68 in-domain speaker similarity.