Generative Diffusion Contrastive Network for Multi-View Clustering

In recent years, Multi-View Clustering (MVC) has been significantly advanced under the influence of deep learning. By integrating heterogeneous data from multiple views, MVC enhances clustering analysis, making multi-view fusion critical to clustering performance. However, there is a problem of low-quality data in multi-view fusion. This problem primarily arises from two reasons: 1) Certain views are contaminated by noisy data. 2) Some views suffer from missing data. This paper proposes a novel Stochastic Generative Diffusion Fusion (SGDF) method to address this problem. SGDF leverages a multiple generative mechanism for the multi-view feature of each sample. It is robust to low-quality data. Building on SGDF, we further present the Generative Diffusion Contrastive Network (GDCN). Extensive experiments show that GDCN achieves the state-of-the-art results in deep MVC tasks. The source code is publicly available at https://github.com/HackerHyper/GDCN.

Fine-Tuning Vision-Language Models for Visual Navigation Assistance

We address vision-language-driven indoor navigation to assist visually impaired individuals in reaching a target location using images and natural language guidance. Traditional navigation systems are ineffective indoors due to the lack of precise location data. Our approach integrates vision and language models to generate step-by-step navigational instructions, enhancing accessibility and independence. We fine-tune the BLIP-2 model with Low Rank Adaptation (LoRA) on a manually annotated indoor navigation dataset. We propose an evaluation metric that refines the BERT F1 score by emphasizing directional and sequential variables, providing a more comprehensive measure of navigational performance. After applying LoRA, the model significantly improved in generating directional instructions, overcoming limitations in the original BLIP-2 model.

Revolution or Hype? Seeking the Limits of Large Models in Hardware Design

Recent breakthroughs in Large Language Models (LLMs) and Large Circuit Models (LCMs) have sparked excitement across the electronic design automation (EDA) community, promising a revolution in circuit design and optimization. Yet, this excitement is met with significant skepticism: Are these AI models a genuine revolution in circuit design, or a temporary wave of inflated expectations? This paper serves as a foundational text for the corresponding ICCAD 2025 panel, bringing together perspectives from leading experts in academia and industry. It critically examines the practical capabilities, fundamental limitations, and future prospects of large AI models in hardware design. The paper synthesizes the core arguments surrounding reliability, scalability, and interpretability, framing the debate on whether these models can meaningfully outperform or complement traditional EDA methods. The result is an authoritative overview offering fresh insights into one of today's most contentious and impactful technology trends.

FakeParts: a New Family of AI-Generated DeepFakes

We introduce FakeParts, a new class of deepfakes characterized by subtle, localized manipulations to specific spatial regions or temporal segments of otherwise authentic videos. Unlike fully synthetic content, these partial manipulations, ranging from altered facial expressions to object substitutions and background modifications, blend seamlessly with real elements, making them particularly deceptive and difficult to detect. To address the critical gap in detection capabilities, we present FakePartsBench, the first large-scale benchmark dataset specifically designed to capture the full spectrum of partial deepfakes. Comprising over 25K videos with pixel-level and frame-level manipulation annotations, our dataset enables comprehensive evaluation of detection methods. Our user studies demonstrate that FakeParts reduces human detection accuracy by over 30% compared to traditional deepfakes, with similar performance degradation observed in state-of-the-art detection models. This work identifies an urgent vulnerability in current deepfake detection approaches and provides the necessary resources to develop more robust methods for partial video manipulations.

Progressive Depth Up-scaling via Optimal Transport

Scaling Large Language Models (LLMs) yields performance gains but incurs substantial training costs. Depth up-scaling offers training efficiency by adding new layers to pre-trained models. However, most existing methods copy or average weights from base layers, neglecting neuron permutation differences. This limitation can potentially cause misalignment that harms performance. Inspired by applying Optimal Transport (OT) for neuron alignment, we propose Optimal Transport Depth Up-Scaling (OpT-DeUS). OpT-DeUS aligns and fuses Transformer blocks in adjacent base layers via OT for new layer creation, to mitigate neuron permutation mismatch between layers. OpT-DeUS achieves better overall performance and offers improved training efficiency than existing methods for continual pre-training and supervised fine-tuning across different model sizes. To further evaluate the impact of interpolation positions, our extensive analysis shows that inserting new layers closer to the top results in higher training efficiency due to shorter back-propagation time while obtaining additional performance gains.

Large-scale Multi-sequence Pretraining for Generalizable MRI Analysis in Versatile Clinical Applications

Multi-sequence Magnetic Resonance Imaging (MRI) offers remarkable versatility, enabling the distinct visualization of different tissue types. Nevertheless, the inherent heterogeneity among MRI sequences poses significant challenges to the generalization capability of deep learning models. These challenges undermine model performance when faced with varying acquisition parameters, thereby severely restricting their clinical utility. In this study, we present PRISM, a foundation model PRe-trained with large-scale multI-Sequence MRI. We collected a total of 64 datasets from both public and private sources, encompassing a wide range of whole-body anatomical structures, with scans spanning diverse MRI sequences. Among them, 336,476 volumetric MRI scans from 34 datasets (8 public and 26 private) were curated to construct the largest multi-organ multi-sequence MRI pretraining corpus to date. We propose a novel pretraining paradigm that disentangles anatomically invariant features from sequence-specific variations in MRI, while preserving high-level semantic representations. We established a benchmark comprising 44 downstream tasks, including disease diagnosis, image segmentation, registration, progression prediction, and report generation. These tasks were evaluated on 32 public datasets and 5 private cohorts. PRISM consistently outperformed both non-pretrained models and existing foundation models, achieving first-rank results in 39 out of 44 downstream benchmarks with statistical significance improvements. These results underscore its ability to learn robust and generalizable representations across unseen data acquired under diverse MRI protocols. PRISM provides a scalable framework for multi-sequence MRI analysis, thereby enhancing the translational potential of AI in radiology. It delivers consistent performance across diverse imaging protocols, reinforcing its clinical applicability.

A Comprehensive Survey of Self-Evolving AI Agents: A New Paradigm Bridging Foundation Models and Lifelong Agentic Systems

Recent advances in large language models have sparked growing interest in AI agents capable of solving complex, real-world tasks. However, most existing agent systems rely on manually crafted configurations that remain static after deployment, limiting their ability to adapt to dynamic and evolving environments. To this end, recent research has explored agent evolution techniques that aim to automatically enhance agent systems based on interaction data and environmental feedback. This emerging direction lays the foundation for self-evolving AI agents, which bridge the static capabilities of foundation models with the continuous adaptability required by lifelong agentic systems. In this survey, we provide a comprehensive review of existing techniques for self-evolving agentic systems. Specifically, we first introduce a unified conceptual framework that abstracts the feedback loop underlying the design of self-evolving agentic systems. The framework highlights four key components: System Inputs, Agent System, Environment, and Optimisers, serving as a foundation for understanding and comparing different strategies. Based on this framework, we systematically review a wide range of self-evolving techniques that target different components of the agent system. We also investigate domain-specific evolution strategies developed for specialised fields such as biomedicine, programming, and finance, where optimisation objectives are tightly coupled with domain constraints. In addition, we provide a dedicated discussion on the evaluation, safety, and ethical considerations for self-evolving agentic systems, which are critical to ensuring their effectiveness and reliability. This survey aims to provide researchers and practitioners with a systematic understanding of self-evolving AI agents, laying the foundation for the development of more adaptive, autonomous, and lifelong agentic systems.

Step More: Going Beyond Single Backpropagation in Meta Learning Based Model Editing

Large Language Models (LLMs) underpin many AI applications, but their static nature makes updating knowledge costly. Model editing offers an efficient alternative by injecting new information through targeted parameter modifications. In particular, meta-learning-based model editing (MLBME) methods have demonstrated notable advantages in both editing effectiveness and efficiency. Despite this, we find that MLBME exhibits suboptimal performance in low-data scenarios, and its training efficiency is bottlenecked by the computation of KL divergence. To address these, we propose $\textbf{S}$tep $\textbf{M}$ore $\textbf{Edit}$ ($\textbf{SMEdit}$), a novel MLBME method that adopts $\textbf{M}$ultiple $\textbf{B}$ackpro$\textbf{P}$agation $\textbf{S}$teps ($\textbf{MBPS}$) to improve editing performance under limited supervision and a norm regularization on weight updates to improve training efficiency. Experimental results on two datasets and two LLMs demonstrate that SMEdit outperforms prior MLBME baselines and the MBPS strategy can be seamlessly integrated into existing methods to further boost their performance. Our code will be released soon.

TalkDep: Clinically Grounded LLM Personas for Conversation-Centric Depression Screening

The increasing demand for mental health services has outpaced the availability of real training data to develop clinical professionals, leading to limited support for the diagnosis of depression. This shortage has motivated the development of simulated or virtual patients to assist in training and evaluation, but existing approaches often fail to generate clinically valid, natural, and diverse symptom presentations. In this work, we embrace the recent advanced language models as the backbone and propose a novel clinician-in-the-loop patient simulation pipeline, TalkDep, with access to diversified patient profiles to develop simulated patients. By conditioning the model on psychiatric diagnostic criteria, symptom severity scales, and contextual factors, our goal is to create authentic patient responses that can better support diagnostic model training and evaluation. We verify the reliability of these simulated patients with thorough assessments conducted by clinical professionals. The availability of validated simulated patients offers a scalable and adaptable resource for improving the robustness and generalisability of automatic depression diagnosis systems.

A Versatile Pathology Co-pilot via Reasoning Enhanced Multimodal Large Language Model

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These models hold particular promise for automating complex tasks that traditionally require expert interpretation of pathologists. However, current MLLM approaches in pathology demonstrate significantly constrained reasoning capabilities, primarily due to their reliance on expensive chain-of-thought annotations. Additionally, existing methods remain limited to simplex application of visual question answering (VQA) at region-of-interest (ROI) level, failing to address the full spectrum of diagnostic needs such as ROI classification, detection, segmentation, whole-slide-image (WSI) classification and VQA in clinical practice. In this study, we present SmartPath-R1, a versatile MLLM capable of simultaneously addressing both ROI-level and WSI-level tasks while demonstrating robust pathological reasoning capability. Our framework combines scale-dependent supervised fine-tuning and task-aware reinforcement fine-tuning, which circumvents the requirement for chain-of-thought supervision by leveraging the intrinsic knowledge within MLLM. Furthermore, SmartPath-R1 integrates multiscale and multitask analysis through a mixture-of-experts mechanism, enabling dynamic processing for diverse tasks. We curate a large-scale dataset comprising 2.3M ROI samples and 188K WSI samples for training and evaluation. Extensive experiments across 72 tasks validate the effectiveness and superiority of the proposed approach. This work represents a significant step toward developing versatile, reasoning-enhanced AI systems for precision pathology.