Efficient Deformable Tissue Reconstruction via Orthogonal Neural Plane

Intraoperative imaging techniques for reconstructing deformable tissues in vivo are pivotal for advanced surgical systems. Existing methods either compromise on rendering quality or are excessively computationally intensive, often demanding dozens of hours to perform, which significantly hinders their practical application. In this paper, we introduce Fast Orthogonal Plane (Forplane), a novel, efficient framework based on neural radiance fields (NeRF) for the reconstruction of deformable tissues. We conceptualize surgical procedures as 4D volumes, and break them down into static and dynamic fields comprised of orthogonal neural planes. This factorization iscretizes the four-dimensional space, leading to a decreased memory usage and faster optimization. A spatiotemporal importance sampling scheme is introduced to improve performance in regions with tool occlusion as well as large motions and accelerate training. An efficient ray marching method is applied to skip sampling among empty regions, significantly improving inference speed. Forplane accommodates both binocular and monocular endoscopy videos, demonstrating its extensive applicability and flexibility. Our experiments, carried out on two in vivo datasets, the EndoNeRF and Hamlyn datasets, demonstrate the effectiveness of our framework. In all cases, Forplane substantially accelerates both the optimization process (by over 100 times) and the inference process (by over 15 times) while maintaining or even improving the quality across a variety of non-rigid deformations. This significant performance improvement promises to be a valuable asset for future intraoperative surgical applications. The code of our project is now available at https://github.com/Loping151/ForPlane.

SQA-SAM: Segmentation Quality Assessment for Medical Images Utilizing the Segment Anything Model

Segmentation quality assessment (SQA) plays a critical role in the deployment of a medical image based AI system. Users need to be informed/alerted whenever an AI system generates unreliable/incorrect predictions. With the introduction of the Segment Anything Model (SAM), a general foundation segmentation model, new research opportunities emerged in how one can utilize SAM for medical image segmentation. In this paper, we propose a novel SQA method, called SQA-SAM, which exploits SAM to enhance the accuracy of quality assessment for medical image segmentation. When a medical image segmentation model (MedSeg) produces predictions for a test image, we generate visual prompts based on the predictions, and SAM is utilized to generate segmentation maps corresponding to the visual prompts. How well MedSeg's segmentation aligns with SAM's segmentation indicates how well MedSeg's segmentation aligns with the general perception of objectness and image region partition. We develop a score measure for such alignment. In experiments, we find that the generated scores exhibit moderate to strong positive correlation (in Pearson correlation and Spearman correlation) with Dice coefficient scores reflecting the true segmentation quality.

Uncertainty Estimation for Safety-critical Scene Segmentation via Fine-grained Reward Maximization

Uncertainty estimation plays an important role for future reliable deployment of deep segmentation models in safety-critical scenarios such as medical applications. However, existing methods for uncertainty estimation have been limited by the lack of explicit guidance for calibrating the prediction risk and model confidence. In this work, we propose a novel fine-grained reward maximization (FGRM) framework, to address uncertainty estimation by directly utilizing an uncertainty metric related reward function with a reinforcement learning based model tuning algorithm. This would benefit the model uncertainty estimation through direct optimization guidance for model calibration. Specifically, our method designs a new uncertainty estimation reward function using the calibration metric, which is maximized to fine-tune an evidential learning pre-trained segmentation model for calibrating prediction risk. Importantly, we innovate an effective fine-grained parameter update scheme, which imposes fine-grained reward-weighting of each network parameter according to the parameter importance quantified by the fisher information matrix. To the best of our knowledge, this is the first work exploring reward optimization for model uncertainty estimation in safety-critical vision tasks. The effectiveness of our method is demonstrated on two large safety-critical surgical scene segmentation datasets under two different uncertainty estimation settings. With real-time one forward pass at inference, our method outperforms state-of-the-art methods by a clear margin on all the calibration metrics of uncertainty estimation, while maintaining a high task accuracy for the segmentation results. Code is available at \url{https://github.com/med-air/FGRM}.

Interactive Navigation in Environments with Traversable Obstacles Using Large Language and Vision-Language Models

This paper proposes an interactive navigation framework by using large language and vision-language models, allowing robots to navigate in environments with traversable obstacles. We utilize the large language model (GPT-3.5) and the open-set Vision-language Model (Grounding DINO) to create an action-aware costmap to perform effective path planning without fine-tuning. With the large models, we can achieve an end-to-end system from textual instructions like "Can you pass through the curtains to deliver medicines to me?", to bounding boxes (e.g., curtains) with action-aware attributes. They can be used to segment LiDAR point clouds into two parts: traversable and untraversable parts, and then an action-aware costmap is constructed for generating a feasible path. The pre-trained large models have great generalization ability and do not require additional annotated data for training, allowing fast deployment in the interactive navigation tasks. We choose to use multiple traversable objects such as curtains and grasses for verification by instructing the robot to traverse them. Besides, traversing curtains in a medical scenario was tested. All experimental results demonstrated the proposed framework's effectiveness and adaptability to diverse environments.

RGBManip: Monocular Image-based Robotic Manipulation through Active Object Pose Estimation

Robotic manipulation requires accurate perception of the environment, which poses a significant challenge due to its inherent complexity and constantly changing nature. In this context, RGB image and point-cloud observations are two commonly used modalities in visual-based robotic manipulation, but each of these modalities have their own limitations. Commercial point-cloud observations often suffer from issues like sparse sampling and noisy output due to the limits of the emission-reception imaging principle. On the other hand, RGB images, while rich in texture information, lack essential depth and 3D information crucial for robotic manipulation. To mitigate these challenges, we propose an image-only robotic manipulation framework that leverages an eye-on-hand monocular camera installed on the robot's parallel gripper. By moving with the robot gripper, this camera gains the ability to actively perceive object from multiple perspectives during the manipulation process. This enables the estimation of 6D object poses, which can be utilized for manipulation. While, obtaining images from more and diverse viewpoints typically improves pose estimation, it also increases the manipulation time. To address this trade-off, we employ a reinforcement learning policy to synchronize the manipulation strategy with active perception, achieving a balance between 6D pose accuracy and manipulation efficiency. Our experimental results in both simulated and real-world environments showcase the state-of-the-art effectiveness of our approach. %, which, to the best of our knowledge, is the first to achieve robust real-world robotic manipulation through active pose estimation. We believe that our method will inspire further research on real-world-oriented robotic manipulation.

ArSDM: Colonoscopy Images Synthesis with Adaptive Refinement Semantic Diffusion Models

Colonoscopy analysis, particularly automatic polyp segmentation and detection, is essential for assisting clinical diagnosis and treatment. However, as medical image annotation is labour- and resource-intensive, the scarcity of annotated data limits the effectiveness and generalization of existing methods. Although recent research has focused on data generation and augmentation to address this issue, the quality of the generated data remains a challenge, which limits the contribution to the performance of subsequent tasks. Inspired by the superiority of diffusion models in fitting data distributions and generating high-quality data, in this paper, we propose an Adaptive Refinement Semantic Diffusion Model (ArSDM) to generate colonoscopy images that benefit the downstream tasks. Specifically, ArSDM utilizes the ground-truth segmentation mask as a prior condition during training and adjusts the diffusion loss for each input according to the polyp/background size ratio. Furthermore, ArSDM incorporates a pre-trained segmentation model to refine the training process by reducing the difference between the ground-truth mask and the prediction mask. Extensive experiments on segmentation and detection tasks demonstrate the generated data by ArSDM could significantly boost the performance of baseline methods.

Visual-Kinematics Graph Learning for Procedure-agnostic Instrument Tip Segmentation in Robotic Surgeries

Accurate segmentation of surgical instrument tip is an important task for enabling downstream applications in robotic surgery, such as surgical skill assessment, tool-tissue interaction and deformation modeling, as well as surgical autonomy. However, this task is very challenging due to the small sizes of surgical instrument tips, and significant variance of surgical scenes across different procedures. Although much effort has been made on visual-based methods, existing segmentation models still suffer from low robustness thus not usable in practice. Fortunately, kinematics data from the robotic system can provide reliable prior for instrument location, which is consistent regardless of different surgery types. To make use of such multi-modal information, we propose a novel visual-kinematics graph learning framework to accurately segment the instrument tip given various surgical procedures. Specifically, a graph learning framework is proposed to encode relational features of instrument parts from both image and kinematics. Next, a cross-modal contrastive loss is designed to incorporate robust geometric prior from kinematics to image for tip segmentation. We have conducted experiments on a private paired visual-kinematics dataset including multiple procedures, i.e., prostatectomy, total mesorectal excision, fundoplication and distal gastrectomy on cadaver, and distal gastrectomy on porcine. The leave-one-procedure-out cross validation demonstrated that our proposed multi-modal segmentation method significantly outperformed current image-based state-of-the-art approaches, exceeding averagely 11.2% on Dice.

Deep Fusion Transformer Network with Weighted Vector-Wise Keypoints Voting for Robust 6D Object Pose Estimation

One critical challenge in 6D object pose estimation from a single RGBD image is efficient integration of two different modalities, i.e., color and depth. In this work, we tackle this problem by a novel Deep Fusion Transformer~(DFTr) block that can aggregate cross-modality features for improving pose estimation. Unlike existing fusion methods, the proposed DFTr can better model cross-modality semantic correlation by leveraging their semantic similarity, such that globally enhanced features from different modalities can be better integrated for improved information extraction. Moreover, to further improve robustness and efficiency, we introduce a novel weighted vector-wise voting algorithm that employs a non-iterative global optimization strategy for precise 3D keypoint localization while achieving near real-time inference. Extensive experiments show the effectiveness and strong generalization capability of our proposed 3D keypoint voting algorithm. Results on four widely used benchmarks also demonstrate that our method outperforms the state-of-the-art methods by large margins.

Value-Informed Skill Chaining for Policy Learning of Long-Horizon Tasks with Surgical Robot

Reinforcement learning is still struggling with solving long-horizon surgical robot tasks which involve multiple steps over an extended duration of time due to the policy exploration challenge. Recent methods try to tackle this problem by skill chaining, in which the long-horizon task is decomposed into multiple subtasks for easing the exploration burden and subtask policies are temporally connected to complete the whole long-horizon task. However, smoothly connecting all subtask policies is difficult for surgical robot scenarios. Not all states are equally suitable for connecting two adjacent subtasks. An undesired terminate state of the previous subtask would make the current subtask policy unstable and result in a failed execution. In this work, we introduce value-informed skill chaining (ViSkill), a novel reinforcement learning framework for long-horizon surgical robot tasks. The core idea is to distinguish which terminal state is suitable for starting all the following subtask policies. To achieve this target, we introduce a state value function that estimates the expected success probability of the entire task given a state. Based on this value function, a chaining policy is learned to instruct subtask policies to terminate at the state with the highest value so that all subsequent policies are more likely to be connected for accomplishing the task. We demonstrate the effectiveness of our method on three complex surgical robot tasks from SurRoL, a comprehensive surgical simulation platform, achieving high task success rates and execution efficiency. Code is available at $\href{https://github.com/med-air/ViSkill}{\text{https://github.com/med-air/ViSkill}}$.

Treatment Outcome Prediction for Intracerebral Hemorrhage via Generative Prognostic Model with Imaging and Tabular Data

Intracerebral hemorrhage (ICH) is the second most common and deadliest form of stroke. Despite medical advances, predicting treat ment outcomes for ICH remains a challenge. This paper proposes a novel prognostic model that utilizes both imaging and tabular data to predict treatment outcome for ICH. Our model is trained on observational data collected from non-randomized controlled trials, providing reliable predictions of treatment success. Specifically, we propose to employ a variational autoencoder model to generate a low-dimensional prognostic score, which can effectively address the selection bias resulting from the non-randomized controlled trials. Importantly, we develop a variational distributions combination module that combines the information from imaging data, non-imaging clinical data, and treatment assignment to accurately generate the prognostic score. We conducted extensive experiments on a real-world clinical dataset of intracerebral hemorrhage. Our proposed method demonstrates a substantial improvement in treatment outcome prediction compared to existing state-of-the-art approaches. Code is available at https://github.com/med-air/TOP-GPM