ClinicalTrialsHub: Bridging Registries and Literature for Comprehensive Clinical Trial Access

We present ClinicalTrialsHub, an interactive search-focused platform that consolidates all data from ClinicalTrials.gov and augments it by automatically extracting and structuring trial-relevant information from PubMed research articles. Our system effectively increases access to structured clinical trial data by 83.8% compared to relying on ClinicalTrials.gov alone, with potential to make access easier for patients, clinicians, researchers, and policymakers, advancing evidence-based medicine. ClinicalTrialsHub uses large language models such as GPT-5.1 and Gemini-3-Pro to enhance accessibility. The platform automatically parses full-text research articles to extract structured trial information, translates user queries into structured database searches, and provides an attributed question-answering system that generates evidence-grounded answers linked to specific source sentences. We demonstrate its utility through a user study involving clinicians, clinical researchers, and PhD students of pharmaceutical sciences and nursing, and a systematic automatic evaluation of its information extraction and question answering capabilities.

A Practical Framework for Evaluating Medical AI Security: Reproducible Assessment of Jailbreaking and Privacy Vulnerabilities Across Clinical Specialties

Medical Large Language Models (LLMs) are increasingly deployed for clinical decision support across diverse specialties, yet systematic evaluation of their robustness to adversarial misuse and privacy leakage remains inaccessible to most researchers. Existing security benchmarks require GPU clusters, commercial API access, or protected health data -- barriers that limit community participation in this critical research area. We propose a practical, fully reproducible framework for evaluating medical AI security under realistic resource constraints. Our framework design covers multiple medical specialties stratified by clinical risk -- from high-risk domains such as emergency medicine and psychiatry to general practice -- addressing jailbreaking attacks (role-playing, authority impersonation, multi-turn manipulation) and privacy extraction attacks. All evaluation utilizes synthetic patient records requiring no IRB approval. The framework is designed to run entirely on consumer CPU hardware using freely available models, eliminating cost barriers. We present the framework specification including threat models, data generation methodology, evaluation protocols, and scoring rubrics. This proposal establishes a foundation for comparative security assessment of medical-specialist models and defense mechanisms, advancing the broader goal of ensuring safe and trustworthy medical AI systems.

MPCM-Net: Multi-scale network integrates partial attention convolution with Mamba for ground-based cloud image segmentation

Ground-based cloud image segmentation is a critical research domain for photovoltaic power forecasting. Current deep learning approaches primarily focus on encoder-decoder architectural refinements. However, existing methodologies exhibit several limitations:(1)they rely on dilated convolutions for multi-scale context extraction, lacking the partial feature effectiveness and interoperability of inter-channel;(2)attention-based feature enhancement implementations neglect accuracy-throughput balance; and (3)the decoder modifications fail to establish global interdependencies among hierarchical local features, limiting inference efficiency. To address these challenges, we propose MPCM-Net, a Multi-scale network that integrates Partial attention Convolutions with Mamba architectures to enhance segmentation accuracy and computational efficiency. Specifically, the encoder incorporates MPAC, which comprises:(1)a MPC block with ParCM and ParSM that enables global spatial interaction across multi-scale cloud formations, and (2)a MPA block combining ParAM and ParSM to extract discriminative features with reduced computational complexity. On the decoder side, a M2B is employed to mitigate contextual loss through a SSHD that maintains linear complexity while enabling deep feature aggregation across spatial and scale dimensions. As a key contribution to the community, we also introduce and release a dataset CSRC, which is a clear-label, fine-grained segmentation benchmark designed to overcome the critical limitations of existing public datasets. Extensive experiments on CSRC demonstrate the superior performance of MPCM-Net over state-of-the-art methods, achieving an optimal balance between segmentation accuracy and inference speed. The dataset and source code will be available at https://github.com/she1110/CSRC.

Generative AI Meets 6G and Beyond: Diffusion Models for Semantic Communications

Semantic communications mark a paradigm shift from bit-accurate transmission toward meaning-centric communication, essential as wireless systems approach theoretical capacity limits. The emergence of generative AI has catalyzed generative semantic communications, where receivers reconstruct content from minimal semantic cues by leveraging learned priors. Among generative approaches, diffusion models stand out for their superior generation quality, stable training dynamics, and rigorous theoretical foundations. However, the field currently lacks systematic guidance connecting diffusion techniques to communication system design, forcing researchers to navigate disparate literatures. This article provides the first comprehensive tutorial on diffusion models for generative semantic communications. We present score-based diffusion foundations and systematically review three technical pillars: conditional diffusion for controllable generation, efficient diffusion for accelerated inference, and generalized diffusion for cross-domain adaptation. In addition, we introduce an inverse problem perspective that reformulates semantic decoding as posterior inference, bridging semantic communications with computational imaging. Through analysis of human-centric, machine-centric, and agent-centric scenarios, we illustrate how diffusion models enable extreme compression while maintaining semantic fidelity and robustness. By bridging generative AI innovations with communication system design, this article aims to establish diffusion models as foundational components of next-generation wireless networks and beyond.

Overview of CHIP 2025 Shared Task 2: Discharge Medication Recommendation for Metabolic Diseases Based on Chinese Electronic Health Records

Discharge medication recommendation plays a critical role in ensuring treatment continuity, preventing readmission, and improving long-term management for patients with chronic metabolic diseases. This paper present an overview of the CHIP 2025 Shared Task 2 competition, which aimed to develop state-of-the-art approaches for automatically recommending appro-priate discharge medications using real-world Chinese EHR data. For this task, we constructed CDrugRed, a high-quality dataset consisting of 5,894 de-identified hospitalization records from 3,190 patients in China. This task is challenging due to multi-label nature of medication recommendation, het-erogeneous clinical text, and patient-specific variability in treatment plans. A total of 526 teams registered, with 167 and 95 teams submitting valid results to the Phase A and Phase B leaderboards, respectively. The top-performing team achieved the highest overall performance on the final test set, with a Jaccard score of 0.5102, F1 score of 0.6267, demonstrating the potential of advanced large language model (LLM)-based ensemble systems. These re-sults highlight both the promise and remaining challenges of applying LLMs to medication recommendation in Chinese EHRs. The post-evaluation phase remains open at https://tianchi.aliyun.com/competition/entrance/532411/.

Achieving Fairness Without Harm via Selective Demographic Experts

As machine learning systems become increasingly integrated into human-centered domains such as healthcare, ensuring fairness while maintaining high predictive performance is critical. Existing bias mitigation techniques often impose a trade-off between fairness and accuracy, inadvertently degrading performance for certain demographic groups. In high-stakes domains like clinical diagnosis, such trade-offs are ethically and practically unacceptable. In this study, we propose a fairness-without-harm approach by learning distinct representations for different demographic groups and selectively applying demographic experts consisting of group-specific representations and personalized classifiers through a no-harm constrained selection. We evaluate our approach on three real-world medical datasets -- covering eye disease, skin cancer, and X-ray diagnosis -- as well as two face datasets. Extensive empirical results demonstrate the effectiveness of our approach in achieving fairness without harm.

SemSteDiff: Generative Diffusion Model-based Coverless Semantic Steganography Communication

Semantic communication (SemCom), as a novel paradigm for future communication systems, has recently attracted much attention due to its superiority in communication efficiency. However, similar to traditional communication, it also suffers from eavesdropping threats. Intelligent eavesdroppers could launch advanced semantic analysis techniques to infer secret semantic information. Therefore, some researchers have designed Semantic Steganography Communication (SemSteCom) scheme to confuse semantic eavesdroppers. However, the state-of-the-art SemSteCom schemes for image transmission rely on the pre-selected cover image, which limits the universality. To address this issue, we propose a Generative Diffusion Model-based Coverless Semantic Steganography Communication (SemSteDiff) scheme to hide secret images into generated stego images. The semantic related private and public keys enable legitimate receiver to decode secret images correctly while the eavesdropper without completely true key-pairs fail to obtain them. Simulation results demonstrate the effectiveness of the plug-and-play design in different Joint Source-Channel Coding (JSCC) frameworks. The comparison results under different eavesdroppers' threats show that, when Signal-to-Noise Ratio (SNR) = 0 dB, the peak signal-to-noise ratio (PSNR) of the legitimate receiver is 4.14 dB higher than that of the eavesdropper.

SurgWound-Bench: A Benchmark for Surgical Wound Diagnosis

Surgical site infection (SSI) is one of the most common and costly healthcare-associated infections and and surgical wound care remains a significant clinical challenge in preventing SSIs and improving patient outcomes. While recent studies have explored the use of deep learning for preliminary surgical wound screening, progress has been hindered by concerns over data privacy and the high costs associated with expert annotation. Currently, no publicly available dataset or benchmark encompasses various types of surgical wounds, resulting in the absence of an open-source Surgical-Wound screening tool. To address this gap: (1) we present SurgWound, the first open-source dataset featuring a diverse array of surgical wound types. It contains 697 surgical wound images annotated by 3 professional surgeons with eight fine-grained clinical attributes. (2) Based on SurgWound, we introduce the first benchmark for surgical wound diagnosis, which includes visual question answering (VQA) and report generation tasks to comprehensively evaluate model performance. (3) Furthermore, we propose a three-stage learning framework, WoundQwen, for surgical wound diagnosis. In the first stage, we employ five independent MLLMs to accurately predict specific surgical wound characteristics. In the second stage, these predictions serve as additional knowledge inputs to two MLLMs responsible for diagnosing outcomes, which assess infection risk and guide subsequent interventions. In the third stage, we train a MLLM that integrates the diagnostic results from the previous two stages to produce a comprehensive report. This three-stage framework can analyze detailed surgical wound characteristics and provide subsequent instructions to patients based on surgical images, paving the way for personalized wound care, timely intervention, and improved patient outcomes.

Adaptive Source-Channel Coding for Semantic Communications

Semantic communications (SemComs) have emerged as a promising paradigm for joint data and task-oriented transmissions, combining the demands for both the bit-accurate delivery and end-to-end (E2E) distortion minimization. However, current joint source-channel coding (JSCC) in SemComs is not compatible with the existing communication systems and cannot adapt to the variations of the sources or the channels, while separate source-channel coding (SSCC) is suboptimal in the finite blocklength regime. To address these issues, we propose an adaptive source-channel coding (ASCC) scheme for SemComs over parallel Gaussian channels, where the deep neural network (DNN)-based semantic source coding and conventional digital channel coding are separately deployed and adaptively designed. To enable efficient adaptation between the source and channel coding, we first approximate the E2E data and semantic distortions as functions of source coding rate and bit error ratio (BER) via logistic regression, where BER is further modeled as functions of signal-to-noise ratio (SNR) and channel coding rate. Then, we formulate the weighted sum E2E distortion minimization problem for joint source-channel coding rate and power allocation over parallel channels, which is solved by the successive convex approximation. Finally, simulation results demonstrate that the proposed ASCC scheme outperforms typical deep JSCC and SSCC schemes for both the single- and parallel-channel scenarios while maintaining full compatibility with practical digital systems.

Generative Diffusion Models for Wireless Networks: Fundamental, Architecture, and State-of-the-Art

With the rapid development of Generative Artificial Intelligence (GAI) technology, Generative Diffusion Models (GDMs) have shown significant empowerment potential in the field of wireless networks due to advantages, such as noise resistance, training stability, controllability, and multimodal generation. Although there have been multiple studies focusing on GDMs for wireless networks, there is still a lack of comprehensive reviews on their technological evolution. Motivated by this, we systematically explore the application of GDMs in wireless networks. Firstly, starting from mathematical principles, we analyze technical advantages of GDMs and present six representative models. Furthermore, we propose the multi-layer wireless network architecture including sensing layer, transmission layer, application layer, and security plane. We also introduce the core mechanisms of GDM at each of the layers. Subsequently, we conduct a rigorous review on existing GDM-based schemes, with a focus on analyzing their innovative points, the role of GDMs, strengths, and weaknesses. Ultimately, we extract key challenges and provide potential solutions, with the aim of providing directional guidance for future research in this field.