A multimodal vision foundation model for generalizable knee pathology

Musculoskeletal disorders represent a leading cause of global disability, creating an urgent demand for precise interpretation of medical imaging. Current artificial intelligence (AI) approaches in orthopedics predominantly rely on task-specific, supervised learning paradigms. These methods are inherently fragmented, require extensive annotated datasets, and often lack generalizability across different modalities and clinical scenarios. The development of foundation models in this field has been constrained by the scarcity of large-scale, curated, and open-source musculoskeletal datasets. To address these challenges, we introduce OrthoFoundation, a multimodal vision foundation model optimized for musculoskeletal pathology. We constructed a pre-training dataset of 1.2 million unlabeled knee X-ray and MRI images from internal and public databases. Utilizing a Dinov3 backbone, the model was trained via self-supervised contrastive learning to capture robust radiological representations. OrthoFoundation achieves state-of-the-art (SOTA) performance across 14 downstream tasks. It attained superior accuracy in X-ray osteoarthritis diagnosis and ranked first in MRI structural injury detection. The model demonstrated remarkable label efficiency, matching supervised baselines using only 50% of labeled data. Furthermore, despite being pre-trained on knee images, OrthoFoundation exhibited exceptional cross-anatomy generalization to the hip, shoulder, and ankle. OrthoFoundation represents a significant advancement toward general-purpose AI for musculoskeletal imaging. By learning fundamental, joint-agnostic radiological semantics from large-scale multimodal data, it overcomes the limitations of conventional models, which provides a robust framework for reducing annotation burdens and enhancing diagnostic accuracy in clinical practice.

Towards Unbiased Source-Free Object Detection via Vision Foundation Models

Source-Free Object Detection (SFOD) has garnered much attention in recent years by eliminating the need of source-domain data in cross-domain tasks, but existing SFOD methods suffer from the Source Bias problem, i.e. the adapted model remains skewed towards the source domain, leading to poor generalization and error accumulation during self-training. To overcome this challenge, we propose Debiased Source-free Object Detection (DSOD), a novel VFM-assisted SFOD framework that can effectively mitigate source bias with the help of powerful VFMs. Specifically, we propose Unified Feature Injection (UFI) module that integrates VFM features into the CNN backbone through Simple-Scale Extension (SSE) and Domain-aware Adaptive Weighting (DAAW). Then, we propose Semantic-aware Feature Regularization (SAFR) that constrains feature learning to prevent overfitting to source domain characteristics. Furthermore, we propose a VFM-free variant, termed DSOD-distill for computation-restricted scenarios through a novel Dual-Teacher distillation scheme. Extensive experiments on multiple benchmarks demonstrate that DSOD outperforms state-of-the-art SFOD methods, achieving 48.1% AP on Normal-to-Foggy weather adaptation, 39.3% AP on Cross-scene adaptation, and 61.4% AP on Synthetic-to-Real adaptation.

The Illusion of Clinical Reasoning: A Benchmark Reveals the Pervasive Gap in Vision-Language Models for Clinical Competency

Background: The rapid integration of foundation models into clinical practice and public health necessitates a rigorous evaluation of their true clinical reasoning capabilities beyond narrow examination success. Current benchmarks, typically based on medical licensing exams or curated vignettes, fail to capture the integrated, multimodal reasoning essential for real-world patient care. Methods: We developed the Bones and Joints (B&J) Benchmark, a comprehensive evaluation framework comprising 1,245 questions derived from real-world patient cases in orthopedics and sports medicine. This benchmark assesses models across 7 tasks that mirror the clinical reasoning pathway, including knowledge recall, text and image interpretation, diagnosis generation, treatment planning, and rationale provision. We evaluated eleven vision-language models (VLMs) and six large language models (LLMs), comparing their performance against expert-derived ground truth. Results: Our results demonstrate a pronounced performance gap between task types. While state-of-the-art models achieved high accuracy, exceeding 90%, on structured multiple-choice questions, their performance markedly declined on open-ended tasks requiring multimodal integration, with accuracy scarcely reaching 60%. VLMs demonstrated substantial limitations in interpreting medical images and frequently exhibited severe text-driven hallucinations, often ignoring contradictory visual evidence. Notably, models specifically fine-tuned for medical applications showed no consistent advantage over general-purpose counterparts. Conclusions: Current artificial intelligence models are not yet clinically competent for complex, multimodal reasoning. Their safe deployment should currently be limited to supportive, text-based roles. Future advancement in core clinical tasks awaits fundamental breakthroughs in multimodal integration and visual understanding.

Run, Ruminate, and Regulate: A Dual-process Thinking System for Vision-and-Language Navigation

Vision-and-Language Navigation (VLN) requires an agent to dynamically explore complex 3D environments following human instructions. Recent research underscores the potential of harnessing large language models (LLMs) for VLN, given their commonsense knowledge and general reasoning capabilities. Despite their strengths, a substantial gap in task completion performance persists between LLM-based approaches and domain experts, as LLMs inherently struggle to comprehend real-world spatial correlations precisely. Additionally, introducing LLMs is accompanied with substantial computational cost and inference latency. To address these issues, we propose a novel dual-process thinking framework dubbed R3, integrating LLMs' generalization capabilities with VLN-specific expertise in a zero-shot manner. The framework comprises three core modules: Runner, Ruminator, and Regulator. The Runner is a lightweight transformer-based expert model that ensures efficient and accurate navigation under regular circumstances. The Ruminator employs a powerful multimodal LLM as the backbone and adopts chain-of-thought (CoT) prompting to elicit structured reasoning. The Regulator monitors the navigation progress and controls the appropriate thinking mode according to three criteria, integrating Runner and Ruminator harmoniously. Experimental results illustrate that R3 significantly outperforms other state-of-the-art methods, exceeding 3.28% and 3.30% in SPL and RGSPL respectively on the REVERIE benchmark. This pronounced enhancement highlights the effectiveness of our method in handling challenging VLN tasks.

QiMeng-SALV: Signal-Aware Learning for Verilog Code Generation

The remarkable progress of Large Language Models (LLMs) presents promising opportunities for Verilog code generation which is significantly important for automated circuit design. The lacking of meaningful functional rewards hinders the preference optimization based on Reinforcement Learning (RL) for producing functionally correct Verilog code. In this paper, we propose Signal-Aware Learning for Verilog code generation (QiMeng-SALV) by leveraging code segments of functionally correct output signal to optimize RL training. Considering Verilog code specifies the structural interconnection of hardware gates and wires so that different output signals are independent, the key insight of QiMeng-SALV is to extract verified signal-aware implementations in partially incorrect modules, so as to enhance the extraction of meaningful functional rewards. Roughly, we verify the functional correctness of signals in generated module by comparing with that of reference module in the training data. Then abstract syntax tree (AST) is employed to identify signal-aware code segments which can provide meaningful functional rewards from erroneous modules. Finally, we introduce signal-aware DPO which is optimized on the correct signal-level code segments, thereby preventing noise and interference from incorrect signals. The proposed QiMeng-SALV underscores the paradigm shift from conventional module-level to fine-grained signal-level optimization in Verilog code generation, addressing the issue of insufficient functional rewards. Experiments demonstrate that our method achieves state-of-the-art performance on VerilogEval and RTLLM, with a 7B parameter model matching the performance of the DeepSeek v3 671B model and significantly outperforming the leading open-source model CodeV trained on the same dataset. Our code is available at https://github.com/zy1xxx/SALV.

Robotic Manipulation via Imitation Learning: Taxonomy, Evolution, Benchmark, and Challenges

Robotic Manipulation (RM) is central to the advancement of autonomous robots, enabling them to interact with and manipulate objects in real-world environments. This survey focuses on RM methodologies that leverage imitation learning, a powerful technique that allows robots to learn complex manipulation skills by mimicking human demonstrations. We identify and analyze the most influential studies in this domain, selected based on community impact and intrinsic quality. For each paper, we provide a structured summary, covering the research purpose, technical implementation, hierarchical classification, input formats, key priors, strengths and limitations, and citation metrics. Additionally, we trace the chronological development of imitation learning techniques within RM policy (RMP), offering a timeline of key technological advancements. Where available, we report benchmark results and perform quantitative evaluations to compare existing methods. By synthesizing these insights, this review provides a comprehensive resource for researchers and practitioners, highlighting both the state of the art and the challenges that lie ahead in the field of robotic manipulation through imitation learning.

ShortFT: Diffusion Model Alignment via Shortcut-based Fine-Tuning

Backpropagation-based approaches aim to align diffusion models with reward functions through end-to-end backpropagation of the reward gradient within the denoising chain, offering a promising perspective. However, due to the computational costs and the risk of gradient explosion associated with the lengthy denoising chain, existing approaches struggle to achieve complete gradient backpropagation, leading to suboptimal results. In this paper, we introduce Shortcut-based Fine-Tuning (ShortFT), an efficient fine-tuning strategy that utilizes the shorter denoising chain. More specifically, we employ the recently researched trajectory-preserving few-step diffusion model, which enables a shortcut over the original denoising chain, and construct a shortcut-based denoising chain of shorter length. The optimization on this chain notably enhances the efficiency and effectiveness of fine-tuning the foundational model. Our method has been rigorously tested and can be effectively applied to various reward functions, significantly improving alignment performance and surpassing state-of-the-art alternatives.

Is Diversity All You Need for Scalable Robotic Manipulation?

Data scaling has driven remarkable success in foundation models for Natural Language Processing (NLP) and Computer Vision (CV), yet the principles of effective data scaling in robotic manipulation remain insufficiently understood. In this work, we investigate the nuanced role of data diversity in robot learning by examining three critical dimensions-task (what to do), embodiment (which robot to use), and expert (who demonstrates)-challenging the conventional intuition of "more diverse is better". Throughout extensive experiments on various robot platforms, we reveal that (1) task diversity proves more critical than per-task demonstration quantity, benefiting transfer from diverse pre-training tasks to novel downstream scenarios; (2) multi-embodiment pre-training data is optional for cross-embodiment transfer-models trained on high-quality single-embodiment data can efficiently transfer to different platforms, showing more desirable scaling property during fine-tuning than multi-embodiment pre-trained models; and (3) expert diversity, arising from individual operational preferences and stochastic variations in human demonstrations, can be confounding to policy learning, with velocity multimodality emerging as a key contributing factor. Based on this insight, we propose a distribution debiasing method to mitigate velocity ambiguity, the yielding GO-1-Pro achieves substantial performance gains of 15%, equivalent to using 2.5 times pre-training data. Collectively, these findings provide new perspectives and offer practical guidance on how to scale robotic manipulation datasets effectively.

Micro-macro Gaussian Splatting with Enhanced Scalability for Unconstrained Scene Reconstruction

Reconstructing 3D scenes from unconstrained image collections poses significant challenges due to variations in appearance. In this paper, we propose Scalable Micro-macro Wavelet-based Gaussian Splatting (SMW-GS), a novel method that enhances 3D reconstruction across diverse scales by decomposing scene representations into global, refined, and intrinsic components. SMW-GS incorporates the following innovations: Micro-macro Projection, which enables Gaussian points to sample multi-scale details with improved diversity; and Wavelet-based Sampling, which refines feature representations using frequency-domain information to better capture complex scene appearances. To achieve scalability, we further propose a large-scale scene promotion strategy, which optimally assigns camera views to scene partitions by maximizing their contributions to Gaussian points, achieving consistent and high-quality reconstructions even in expansive environments. Extensive experiments demonstrate that SMW-GS significantly outperforms existing methods in both reconstruction quality and scalability, particularly excelling in large-scale urban environments with challenging illumination variations. Project is available at https://github.com/Kidleyh/SMW-GS.

QiMeng: Fully Automated Hardware and Software Design for Processor Chip

Processor chip design technology serves as a key frontier driving breakthroughs in computer science and related fields. With the rapid advancement of information technology, conventional design paradigms face three major challenges: the physical constraints of fabrication technologies, the escalating demands for design resources, and the increasing diversity of ecosystems. Automated processor chip design has emerged as a transformative solution to address these challenges. While recent breakthroughs in Artificial Intelligence (AI), particularly Large Language Models (LLMs) techniques, have opened new possibilities for fully automated processor chip design, substantial challenges remain in establishing domain-specific LLMs for processor chip design. In this paper, we propose QiMeng, a novel system for fully automated hardware and software design of processor chips. QiMeng comprises three hierarchical layers. In the bottom-layer, we construct a domain-specific Large Processor Chip Model (LPCM) that introduces novel designs in architecture, training, and inference, to address key challenges such as knowledge representation gap, data scarcity, correctness assurance, and enormous solution space. In the middle-layer, leveraging the LPCM's knowledge representation and inference capabilities, we develop the Hardware Design Agent and the Software Design Agent to automate the design of hardware and software for processor chips. Currently, several components of QiMeng have been completed and successfully applied in various top-layer applications, demonstrating significant advantages and providing a feasible solution for efficient, fully automated hardware/software design of processor chips. Future research will focus on integrating all components and performing iterative top-down and bottom-up design processes to establish a comprehensive QiMeng system.