Rapid hyperspectral photothermal mid-infrared spectroscopic imaging from sparse data for gynecologic cancer tissue subtyping

Ovarian cancer detection has traditionally relied on a multi-step process that includes biopsy, tissue staining, and morphological analysis by experienced pathologists. While widely practiced, this conventional approach suffers from several drawbacks: it is qualitative, time-intensive, and heavily dependent on the quality of staining. Mid-infrared (MIR) hyperspectral photothermal imaging is a label-free, biochemically quantitative technology that, when combined with machine learning algorithms, can eliminate the need for staining and provide quantitative results comparable to traditional histology. However, this technology is slow. This work presents a novel approach to MIR photothermal imaging that enhances its speed by an order of magnitude. Our method significantly accelerates data collection by capturing a combination of high-resolution and interleaved, lower-resolution infrared band images and applying computational techniques for data interpolation. We effectively minimize data collection requirements by leveraging sparse data acquisition and employing curvelet-based reconstruction algorithms. This method enables the reconstruction of high-quality, high-resolution images from undersampled datasets and achieving a 10X improvement in data acquisition time. We assessed the performance of our sparse imaging methodology using a variety of quantitative metrics, including mean squared error (MSE), structural similarity index (SSIM), and tissue subtype classification accuracies, employing both random forest and convolutional neural network (CNN) models, accompanied by ROC curves. Our statistically robust analysis, based on data from 100 ovarian cancer patient samples and over 65 million data points, demonstrates the method's capability to produce superior image quality and accurately distinguish between different gynecological tissue types with segmentation accuracy exceeding 95%.

From Generalization to Precision: Exploring SAM for Tool Segmentation in Surgical Environments

Purpose: Accurate tool segmentation is essential in computer-aided procedures. However, this task conveys challenges due to artifacts' presence and the limited training data in medical scenarios. Methods that generalize to unseen data represent an interesting venue, where zero-shot segmentation presents an option to account for data limitation. Initial exploratory works with the Segment Anything Model (SAM) show that bounding-box-based prompting presents notable zero-short generalization. However, point-based prompting leads to a degraded performance that further deteriorates under image corruption. We argue that SAM drastically over-segment images with high corruption levels, resulting in degraded performance when only a single segmentation mask is considered, while the combination of the masks overlapping the object of interest generates an accurate prediction. Method: We use SAM to generate the over-segmented prediction of endoscopic frames. Then, we employ the ground-truth tool mask to analyze the results of SAM when the best single mask is selected as prediction and when all the individual masks overlapping the object of interest are combined to obtain the final predicted mask. We analyze the Endovis18 and Endovis17 instrument segmentation datasets using synthetic corruptions of various strengths and an In-House dataset featuring counterfactually created real-world corruptions. Results: Combining the over-segmented masks contributes to improvements in the IoU. Furthermore, selecting the best single segmentation presents a competitive IoU score for clean images. Conclusions: Combined SAM predictions present improved results and robustness up to a certain corruption level. However, appropriate prompting strategies are fundamental for implementing these models in the medical domain.

Low-Frequency Black-Box Backdoor Attack via Evolutionary Algorithm

While convolutional neural networks (CNNs) have achieved success in computer vision tasks, it is vulnerable to backdoor attacks. Such attacks could mislead the victim model to make attacker-chosen prediction with a specific trigger pattern. Until now, the trigger injection of existing attacks is mainly limited to spatial domain. Recent works take advantage of perceptual properties of planting specific patterns in the frequency domain, which only reflect indistinguishable pixel-wise perturbations in pixel domain. However, in the black-box setup, the inaccessibility of training process often renders more complex trigger designs. Existing frequency attacks simply handcraft the magnitude of spectrum, introducing anomaly frequency disparities between clean and poisoned data and taking risks of being removed by image processing operations (such as lossy compression and filtering). In this paper, we propose a robust low-frequency black-box backdoor attack (LFBA), which minimally perturbs low-frequency components of frequency spectrum and maintains the perceptual similarity in spatial space simultaneously. The key insight of our attack restrict the search for the optimal trigger to low-frequency region that can achieve high attack effectiveness, robustness against image transformation defenses and stealthiness in dual space. We utilize simulated annealing (SA), a form of evolutionary algorithm, to optimize the properties of frequency trigger including the number of manipulated frequency bands and the perturbation of each frequency component, without relying on the knowledge from the victim classifier. Extensive experiments on real-world datasets verify the effectiveness and robustness of LFBA against image processing operations and the state-of-the-art backdoor defenses, as well as its inherent stealthiness in both spatial and frequency space, making it resilient against frequency inspection.

HINT: High-quality INPainting Transformer with Mask-Aware Encoding and Enhanced Attention

Existing image inpainting methods leverage convolution-based downsampling approaches to reduce spatial dimensions. This may result in information loss from corrupted images where the available information is inherently sparse, especially for the scenario of large missing regions. Recent advances in self-attention mechanisms within transformers have led to significant improvements in many computer vision tasks including inpainting. However, limited by the computational costs, existing methods cannot fully exploit the efficacy of long-range modelling capabilities of such models. In this paper, we propose an end-to-end High-quality INpainting Transformer, abbreviated as HINT, which consists of a novel mask-aware pixel-shuffle downsampling module (MPD) to preserve the visible information extracted from the corrupted image while maintaining the integrity of the information available for high-level inferences made within the model. Moreover, we propose a Spatially-activated Channel Attention Layer (SCAL), an efficient self-attention mechanism interpreting spatial awareness to model the corrupted image at multiple scales. To further enhance the effectiveness of SCAL, motivated by recent advanced in speech recognition, we introduce a sandwich structure that places feed-forward networks before and after the SCAL module. We demonstrate the superior performance of HINT compared to contemporary state-of-the-art models on four datasets, CelebA, CelebA-HQ, Places2, and Dunhuang.

An Efficient MLP-based Point-guided Segmentation Network for Ore Images with Ambiguous Boundary

The precise segmentation of ore images is critical to the successful execution of the beneficiation process. Due to the homogeneous appearance of the ores, which leads to low contrast and unclear boundaries, accurate segmentation becomes challenging, and recognition becomes problematic. This paper proposes a lightweight framework based on Multi-Layer Perceptron (MLP), which focuses on solving the problem of edge burring. Specifically, we introduce a lightweight backbone better suited for efficiently extracting low-level features. Besides, we design a feature pyramid network consisting of two MLP structures that balance local and global information thus enhancing detection accuracy. Furthermore, we propose a novel loss function that guides the prediction points to match the instance edge points to achieve clear object boundaries. We have conducted extensive experiments to validate the efficacy of our proposed method. Our approach achieves a remarkable processing speed of over 27 frames per second (FPS) with a model size of only 73 MB. Moreover, our method delivers a consistently high level of accuracy, with impressive performance scores of 60.4 and 48.9 in~$AP_{50}^{box}$ and~$AP_{50}^{mask}$ respectively, as compared to the currently available state-of-the-art techniques, when tested on the ore image dataset. The source code will be released at \url{https://github.com/MVME-HBUT/ORENEXT}.

In Defense and Revival of Bayesian Filtering for Thermal Infrared Object Tracking

Deep learning-based methods monopolize the latest research in the field of thermal infrared (TIR) object tracking. However, relying solely on deep learning models to obtain better tracking results requires carefully selecting feature information that is beneficial to representing the target object and designing a reasonable template update strategy, which undoubtedly increases the difficulty of model design. Thus, recent TIR tracking methods face many challenges in complex scenarios. This paper introduces a novel Deep Bayesian Filtering (DBF) method to enhance TIR tracking in these challenging situations. DBF is distinctive in its dual-model structure: the system and observation models. The system model leverages motion data to estimate the potential positions of the target object based on two-dimensional Brownian motion, thus generating a prior probability. Following this, the observation model comes into play upon capturing the TIR image. It serves as a classifier and employs infrared information to ascertain the likelihood of these estimated positions, creating a likelihood probability. According to the guidance of the two models, the position of the target object can be determined, and the template can be dynamically updated. Experimental analysis across several benchmark datasets reveals that DBF achieves competitive performance, surpassing most existing TIR tracking methods in complex scenarios.

AlignMiF: Geometry-Aligned Multimodal Implicit Field for LiDAR-Camera Joint Synthesis

Neural implicit fields have been a de facto standard in novel view synthesis. Recently, there exist some methods exploring fusing multiple modalities within a single field, aiming to share implicit features from different modalities to enhance reconstruction performance. However, these modalities often exhibit misaligned behaviors: optimizing for one modality, such as LiDAR, can adversely affect another, like camera performance, and vice versa. In this work, we conduct comprehensive analyses on the multimodal implicit field of LiDAR-camera joint synthesis, revealing the underlying issue lies in the misalignment of different sensors. Furthermore, we introduce AlignMiF, a geometrically aligned multimodal implicit field with two proposed modules: Geometry-Aware Alignment (GAA) and Shared Geometry Initialization (SGI). These modules effectively align the coarse geometry across different modalities, significantly enhancing the fusion process between LiDAR and camera data. Through extensive experiments across various datasets and scenes, we demonstrate the effectiveness of our approach in facilitating better interaction between LiDAR and camera modalities within a unified neural field. Specifically, our proposed AlignMiF, achieves remarkable improvement over recent implicit fusion methods (+2.01 and +3.11 image PSNR on the KITTI-360 and Waymo datasets) and consistently surpasses single modality performance (13.8% and 14.2% reduction in LiDAR Chamfer Distance on the respective datasets).

Vision Transformers with Natural Language Semantics

Tokens or patches within Vision Transformers (ViT) lack essential semantic information, unlike their counterparts in natural language processing (NLP). Typically, ViT tokens are associated with rectangular image patches that lack specific semantic context, making interpretation difficult and failing to effectively encapsulate information. We introduce a novel transformer model, Semantic Vision Transformers (sViT), which leverages recent progress on segmentation models to design novel tokenizer strategies. sViT effectively harnesses semantic information, creating an inductive bias reminiscent of convolutional neural networks while capturing global dependencies and contextual information within images that are characteristic of transformers. Through validation using real datasets, sViT demonstrates superiority over ViT, requiring less training data while maintaining similar or superior performance. Furthermore, sViT demonstrates significant superiority in out-of-distribution generalization and robustness to natural distribution shifts, attributed to its scale invariance semantic characteristic. Notably, the use of semantic tokens significantly enhances the model's interpretability. Lastly, the proposed paradigm facilitates the introduction of new and powerful augmentation techniques at the token (or segment) level, increasing training data diversity and generalization capabilities. Just as sentences are made of words, images are formed by semantic objects; our proposed methodology leverages recent progress in object segmentation and takes an important and natural step toward interpretable and robust vision transformers.

Bit Distribution Study and Implementation of Spatial Quality Map in the JPEG-AI Standardization

Currently, there is a high demand for neural network-based image compression codecs. These codecs employ non-linear transforms to create compact bit representations and facilitate faster coding speeds on devices compared to the hand-crafted transforms used in classical frameworks. The scientific and industrial communities are highly interested in these properties, leading to the standardization effort of JPEG-AI. The JPEG-AI verification model has been released and is currently under development for standardization. Utilizing neural networks, it can outperform the classic codec VVC intra by over 10% BD-rate operating at base operation point. Researchers attribute this success to the flexible bit distribution in the spatial domain, in contrast to VVC intra's anchor that is generated with a constant quality point. However, our study reveals that VVC intra displays a more adaptable bit distribution structure through the implementation of various block sizes. As a result of our observations, we have proposed a spatial bit allocation method to optimize the JPEG-AI verification model's bit distribution and enhance the visual quality. Furthermore, by applying the VVC bit distribution strategy, the objective performance of JPEG-AI verification mode can be further improved, resulting in a maximum gain of 0.45 dB in PSNR-Y.

Enhancing Continuous Domain Adaptation with Multi-Path Transfer Curriculum

Addressing the large distribution gap between training and testing data has long been a challenge in machine learning, giving rise to fields such as transfer learning and domain adaptation. Recently, Continuous Domain Adaptation (CDA) has emerged as an effective technique, closing this gap by utilizing a series of intermediate domains. This paper contributes a novel CDA method, W-MPOT, which rigorously addresses the domain ordering and error accumulation problems overlooked by previous studies. Specifically, we construct a transfer curriculum over the source and intermediate domains based on Wasserstein distance, motivated by theoretical analysis of CDA. Then we transfer the source model to the target domain through multiple valid paths in the curriculum using a modified version of continuous optimal transport. A bidirectional path consistency constraint is introduced to mitigate the impact of accumulated mapping errors during continuous transfer. We extensively evaluate W-MPOT on multiple datasets, achieving up to 54.1\% accuracy improvement on multi-session Alzheimer MR image classification and 94.7\% MSE reduction on battery capacity estimation.