Abstract:This paper aims to model 3D human motion across domains, where a single model is expected to handle multiple modalities, tasks, and datasets. Existing cross-domain models often rely on domain-specific components and multi-stage training, which limits their practicality and scalability. To overcome these challenges, we propose a new setting to train a unified cross-domain model through a single process, eliminating the need for domain-specific components and multi-stage training. We first introduce Pose-in-Context (PiC), which leverages in-context learning to create a pose-centric cross-domain model. While PiC generalizes across multiple pose-based tasks and datasets, it encounters difficulties with modality diversity, prompting strategy, and contextual dependency handling. We thus propose Human-in-Context (HiC), an extension of PiC that broadens generalization across modalities, tasks, and datasets. HiC combines pose and mesh representations within a unified framework, expands task coverage, and incorporates larger-scale datasets. Additionally, HiC introduces a max-min similarity prompt sampling strategy to enhance generalization across diverse domains and a network architecture with dual-branch context injection for improved handling of contextual dependencies. Extensive experimental results show that HiC performs better than PiC in terms of generalization, data scale, and performance across a wide range of domains. These results demonstrate the potential of HiC for building a unified cross-domain 3D human motion model with improved flexibility and scalability. The source codes and models are available at https://github.com/BradleyWang0416/Human-in-Context.
Abstract:The core role of medical images in disease diagnosis makes their quality directly affect the accuracy of clinical judgment. However, due to factors such as low-dose scanning, equipment limitations and imaging artifacts, medical images are often accompanied by non-uniform noise interference, which seriously affects structure recognition and lesion detection. This paper proposes a medical image adaptive denoising model (MI-ND) that integrates multi-scale convolutional and Transformer architecture, introduces a noise level estimator (NLE) and a noise adaptive attention module (NAAB), and realizes channel-spatial attention regulation and cross-modal feature fusion driven by noise perception. Systematic testing is carried out on multimodal public datasets. Experiments show that this method significantly outperforms the comparative methods in image quality indicators such as PSNR, SSIM, and LPIPS, and improves the F1 score and ROC-AUC in downstream diagnostic tasks, showing strong prac-tical value and promotional potential. The model has outstanding benefits in structural recovery, diagnostic sensitivity, and cross-modal robustness, and provides an effective solution for medical image enhancement and AI-assisted diagnosis and treatment.
Abstract:Remarkable progress in 2D Vision-Language Models (VLMs) has spurred interest in extending them to 3D settings for tasks like 3D Question Answering, Dense Captioning, and Visual Grounding. Unlike 2D VLMs that typically process images through an image encoder, 3D scenes, with their intricate spatial structures, allow for diverse model architectures. Based on their encoder design, this paper categorizes recent 3D VLMs into 3D object-centric, 2D image-based, and 3D scene-centric approaches. Despite the architectural similarity of 3D scene-centric VLMs to their 2D counterparts, they have exhibited comparatively lower performance compared with the latest 3D object-centric and 2D image-based approaches. To understand this gap, we conduct an in-depth analysis, revealing that 3D scene-centric VLMs show limited reliance on the 3D scene encoder, and the pre-train stage appears less effective than in 2D VLMs. Furthermore, we observe that data scaling benefits are less pronounced on larger datasets. Our investigation suggests that while these models possess cross-modal alignment capabilities, they tend to over-rely on linguistic cues and overfit to frequent answer distributions, thereby diminishing the effective utilization of the 3D encoder. To address these limitations and encourage genuine 3D scene understanding, we introduce a novel 3D Relevance Discrimination QA dataset designed to disrupt shortcut learning and improve 3D understanding. Our findings highlight the need for advanced evaluation and improved strategies for better 3D understanding in 3D VLMs.
Abstract:Precise recognition, editing, and generation of molecules are essential prerequisites for both chemists and AI systems tackling various chemical tasks. We present MolLangBench, a comprehensive benchmark designed to evaluate fundamental molecule-language interface tasks: language-prompted molecular structure recognition, editing, and generation. To ensure high-quality, unambiguous, and deterministic outputs, we construct the recognition tasks using automated cheminformatics tools, and curate editing and generation tasks through rigorous expert annotation and validation. MolLangBench supports the evaluation of models that interface language with different molecular representations, including linear strings, molecular images, and molecular graphs. Evaluations of state-of-the-art models reveal significant limitations: the strongest model (o3) achieves $79.2\%$ and $78.5\%$ accuracy on recognition and editing tasks, which are intuitively simple for humans, and performs even worse on the generation task, reaching only $29.0\%$ accuracy. These results highlight the shortcomings of current AI systems in handling even preliminary molecular recognition and manipulation tasks. We hope MolLangBench will catalyze further research toward more effective and reliable AI systems for chemical applications.
Abstract:Evolution equations, including both ordinary differential equations (ODEs) and partial differential equations (PDEs), play a pivotal role in modeling dynamic systems. However, achieving accurate long-time integration for these equations remains a significant challenge. While physics-informed neural networks (PINNs) provide a mesh-free framework for solving PDEs, they often suffer from temporal error accumulation, which limits their effectiveness in capturing long-time behaviors. To alleviate this issue, we propose integral regularization PINNs (IR-PINNs), a novel approach that enhances temporal accuracy by incorporating an integral-based residual term into the loss function. This method divides the entire time interval into smaller sub-intervals and enforces constraints over these sub-intervals, thereby improving the resolution and correlation of temporal dynamics. Furthermore, IR-PINNs leverage adaptive sampling to dynamically refine the distribution of collocation points based on the evolving solution, ensuring higher accuracy in regions with sharp gradients or rapid variations. Numerical experiments on benchmark problems demonstrate that IR-PINNs outperform original PINNs and other state-of-the-art methods in capturing long-time behaviors, offering a robust and accurate solution for evolution equations.
Abstract:Recent advancements in multi-modal 3D pre-training methods have shown promising efficacy in learning joint representations of text, images, and point clouds. However, adopting point clouds as 3D representation fails to fully capture the intricacies of the 3D world and exhibits a noticeable gap between the discrete points and the dense 2D pixels of images. To tackle this issue, we propose UniGS, integrating 3D Gaussian Splatting (3DGS) into multi-modal pre-training to enhance the 3D representation. We first rely on the 3DGS representation to model the 3D world as a collection of 3D Gaussians with color and opacity, incorporating all the information of the 3D scene while establishing a strong connection with 2D images. Then, to achieve Language-Image-3D pertaining, UniGS starts with a pre-trained vision-language model to establish a shared visual and textual space through extensive real-world image-text pairs. Subsequently, UniGS employs a 3D encoder to align the optimized 3DGS with the Language-Image representations to learn unified multi-modal representations. To facilitate the extraction of global explicit 3D features by the 3D encoder and achieve better cross-modal alignment, we additionally introduce a novel Gaussian-Aware Guidance module that guides the learning of fine-grained representations of the 3D domain. Through extensive experiments across the Objaverse, ABO, MVImgNet and SUN RGBD datasets with zero-shot classification, text-driven retrieval and open-world understanding tasks, we demonstrate the effectiveness of UniGS in learning a more general and stronger aligned multi-modal representation. Specifically, UniGS achieves leading results across different 3D tasks with remarkable improvements over previous SOTA, Uni3D, including on zero-shot classification (+9.36%), text-driven retrieval (+4.3%) and open-world understanding (+7.92%).
Abstract:As data continues to grow in volume and complexity across domains such as finance, manufacturing, and healthcare, effective anomaly detection is essential for identifying irregular patterns that may signal critical issues. Recently, foundation models (FMs) have emerged as a powerful tool for advancing anomaly detection. They have demonstrated unprecedented capabilities in enhancing anomaly identification, generating detailed data descriptions, and providing visual explanations. This survey presents the first comprehensive review of recent advancements in FM-based anomaly detection. We propose a novel taxonomy that classifies FMs into three categories based on their roles in anomaly detection tasks, i.e., as encoders, detectors, or interpreters. We provide a systematic analysis of state-of-the-art methods and discuss key challenges in leveraging FMs for improved anomaly detection. We also outline future research directions in this rapidly evolving field.
Abstract:Recent advancements in AI for biological research focus on integrating molecular data with natural language to accelerate drug discovery. However, the scarcity of high-quality annotations limits progress in this area. This paper introduces LA$^3$, a Language-based Automatic Annotation Augmentation framework that leverages large language models to augment existing datasets, thereby improving AI training. We demonstrate the effectiveness of LA$^3$ by creating an enhanced dataset, LaChEBI-20, where we systematically rewrite the annotations of molecules from an established dataset. These rewritten annotations preserve essential molecular information while providing more varied sentence structures and vocabulary. Using LaChEBI-20, we train LaMolT5 based on a benchmark architecture to learn the mapping between molecular representations and augmented annotations. Experimental results on text-based *de novo* molecule generation and molecule captioning demonstrate that LaMolT5 outperforms state-of-the-art models. Notably, incorporating LA$^3$ leads to improvements of up to 301% over the benchmark architecture. Furthermore, we validate the effectiveness of LA$^3$ notable applications in *image*, *text* and *graph* tasks, affirming its versatility and utility.
Abstract:Human Mesh Reconstruction (HMR) from monocular video plays an important role in human-robot interaction and collaboration. However, existing video-based human mesh reconstruction methods face a trade-off between accurate reconstruction and smooth motion. These methods design networks based on either RNNs or attention mechanisms to extract local temporal correlations or global temporal dependencies, but the lack of complementary long-term information and local details limits their performance. To address this problem, we propose a \textbf{D}ual-branch \textbf{G}raph \textbf{T}ransformer network for 3D human mesh \textbf{R}econstruction from video, named DGTR. DGTR employs a dual-branch network including a Global Motion Attention (GMA) branch and a Local Details Refine (LDR) branch to parallelly extract long-term dependencies and local crucial information, helping model global human motion and local human details (e.g., local motion, tiny movement). Specifically, GMA utilizes a global transformer to model long-term human motion. LDR combines modulated graph convolutional networks and the transformer framework to aggregate local information in adjacent frames and extract crucial information of human details. Experiments demonstrate that our DGTR outperforms state-of-the-art video-based methods in reconstruction accuracy and maintains competitive motion smoothness. Moreover, DGTR utilizes fewer parameters and FLOPs, which validate the effectiveness and efficiency of the proposed DGTR. Code is publicly available at \href{https://github.com/TangTao-PKU/DGTR}{\textcolor{myBlue}{https://github.com/TangTao-PKU/DGTR}}.
Abstract:Although existing video-based 3D human mesh recovery methods have made significant progress, simultaneously estimating human pose and shape from low-resolution image features limits their performance. These image features lack sufficient spatial information about the human body and contain various noises (e.g., background, lighting, and clothing), which often results in inaccurate pose and inconsistent motion. Inspired by the rapid advance in human pose estimation, we discover that compared to image features, skeletons inherently contain accurate human pose and motion. Therefore, we propose a novel semiAnalytical Regressor using disenTangled Skeletal representations for human mesh recovery from videos, called ARTS. Specifically, a skeleton estimation and disentanglement module is proposed to estimate the 3D skeletons from a video and decouple them into disentangled skeletal representations (i.e., joint position, bone length, and human motion). Then, to fully utilize these representations, we introduce a semi-analytical regressor to estimate the parameters of the human mesh model. The regressor consists of three modules: Temporal Inverse Kinematics (TIK), Bone-guided Shape Fitting (BSF), and Motion-Centric Refinement (MCR). TIK utilizes joint position to estimate initial pose parameters and BSF leverages bone length to regress bone-aligned shape parameters. Finally, MCR combines human motion representation with image features to refine the initial human model parameters. Extensive experiments demonstrate that our ARTS surpasses existing state-of-the-art video-based methods in both per-frame accuracy and temporal consistency on popular benchmarks: 3DPW, MPI-INF-3DHP, and Human3.6M. Code is available at https://github.com/TangTao-PKU/ARTS.