A Multi-Stage Validation Framework for Trustworthy Large-scale Clinical Information Extraction using Large Language Models

Large language models (LLMs) show promise for extracting clinically meaningful information from unstructured health records, yet their translation into real-world settings is constrained by the lack of scalable and trustworthy validation approaches. Conventional evaluation methods rely heavily on annotation-intensive reference standards or incomplete structured data, limiting feasibility at population scale. We propose a multi-stage validation framework for LLM-based clinical information extraction that enables rigorous assessment under weak supervision. The framework integrates prompt calibration, rule-based plausibility filtering, semantic grounding assessment, targeted confirmatory evaluation using an independent higher-capacity judge LLM, selective expert review, and external predictive validity analysis to quantify uncertainty and characterize error modes without exhaustive manual annotation. We applied this framework to extraction of substance use disorder (SUD) diagnoses across 11 substance categories from 919,783 clinical notes. Rule-based filtering and semantic grounding removed 14.59% of LLM-positive extractions that were unsupported, irrelevant, or structurally implausible. For high-uncertainty cases, the judge LLM's assessments showed substantial agreement with subject matter expert review (Gwet's AC1=0.80). Using judge-evaluated outputs as references, the primary LLM achieved an F1 score of 0.80 under relaxed matching criteria. LLM-extracted SUD diagnoses also predicted subsequent engagement in SUD specialty care more accurately than structured-data baselines (AUC=0.80). These findings demonstrate that scalable, trustworthy deployment of LLM-based clinical information extraction is feasible without annotation-intensive evaluation.

MemReader: From Passive to Active Extraction for Long-Term Agent Memory

Long-term memory is fundamental for personalized and autonomous agents, yet populating it remains a bottleneck. Existing systems treat memory extraction as a one-shot, passive transcription from context to structured entries, which struggles with noisy dialogue, missing references, and cross-turn dependencies, leading to memory pollution, low-value writes, and inconsistency. In this paper, we introduce the MemReader family for active long-term memory extraction in agent systems: MemReader-0.6B, a compact and cost-efficient passive extractor distilled for accurate and schema-consistent structured outputs, and MemReader-4B, an active extractor optimized with Group Relative Policy Optimization (GRPO) to make memory writing decisions. Under a ReAct-style paradigm, MemReader-4B explicitly evaluates information value, reference ambiguity, and completeness before acting, and can selectively write memories, defer incomplete inputs, retrieve historical context, or discard irrelevant chatter. Experiments on LOCOMO, LongMemEval, and HaluMem show that MemReader consistently outperforms existing extraction-based baselines. In particular, MemReader-4B achieves state-of-the-art performance on tasks involving knowledge updating, temporal reasoning, and hallucination reduction. These results suggest that effective agent memory requires not merely extracting more information, but performing reasoning-driven and selective memory extraction to build low-noise and dynamically evolving long-term memory. Furthermore, MemReader has been integrated into MemOS and is being deployed in real-world applications. To support future research and adoption, we release the models and provide public API access.

ReplicateAnyScene: Zero-Shot Video-to-3D Composition via Textual-Visual-Spatial Alignment

Humans exhibit an innate capacity to rapidly perceive and segment objects from video observations, and even mentally assemble them into structured 3D scenes. Replicating such capability, termed compositional 3D reconstruction, is pivotal for the advancement of Spatial Intelligence and Embodied AI. However, existing methods struggle to achieve practical deployment due to the insufficient integration of cross-modal information, leaving them dependent on manual object prompting, reliant on auxiliary visual inputs, and restricted to overly simplistic scenes by training biases. To address these limitations, we propose ReplicateAnyScene, a framework capable of fully automated and zero-shot transformation of casually captured videos into compositional 3D scenes. Specifically, our pipeline incorporates a five-stage cascade to extract and structurally align generic priors from vision foundation models across textual, visual, and spatial dimensions, grounding them into structured 3D representations and ensuring semantic coherence and physical plausibility of the constructed scenes. To facilitate a more comprehensive evaluation of this task, we further introduce the C3DR benchmark to assess reconstruction quality from diverse aspects. Extensive experiments demonstrate the superiority of our method over existing baselines in generating high-quality compositional 3D scenes.

STIndex: A Context-Aware Multi-Dimensional Spatiotemporal Information Extraction System

Extracting structured knowledge from unstructured data still faces practical limitations: entity and event extraction pipelines remain brittle, knowledge graph construction requires costly ontology engineering, and cross-domain generalization is rarely production-ready. In contrast, space and time provide universal contextual anchors that naturally align heterogeneous information and benefit downstream tasks such as retrieval and reasoning. We introduce \textbf{STIndex}, an end-to-end system that structures unstructured content into a multidimensional spatiotemporal data warehouse. Users define domain-specific analysis dimensions with configurable hierarchies, while large language models perform context-aware extraction and grounding. \textbf{STIndex} integrates document-level memory, geocoding correction, and quality validation, and offers an interactive analytics dashboard for visualization, clustering, burst detection, and entity network analysis. In evaluation on a public health benchmark, \textbf{STIndex} improves spatiotemporal entity extraction F1 by 4.37\% (GPT-4o-mini) and 3.60\% (Qwen3-8B). A live demonstration and open-source code are available at https://stindex.ai4wa.com/dashboard.

UHD Low-Light Image Enhancement via Real-Time Enhancement Methods with Clifford Information Fusion

Considering efficiency, ultra-high-definition (UHD) low-light image restoration is extremely challenging. Existing methods based on Transformer architectures or high-dimensional complex convolutional neural networks often suffer from the "memory wall" bottleneck, failing to achieve millisecond-level inference on edge devices. To address this issue, we propose a novel real-time UHD low-light enhancement network based on geometric feature fusion using Clifford algebra in 2D Euclidean space. First, we construct a four-layer feature pyramid with gradually increasing resolution, which decomposes input images into low-frequency and high-frequency structural components via a Gaussian blur kernel, and adopts a lightweight U-Net based on depthwise separable convolution for dual-branch feature extraction. Second, to resolve structural information loss and artifacts from traditional high-low frequency feature fusion, we introduce spatially aware Clifford algebra, which maps feature tensors to a multivector space (scalars, vectors, bivectors) and uses Clifford similarity to aggregate features while suppressing noise and preserving textures. In the reconstruction stage, the network outputs adaptive Gamma and Gain maps, which perform physically constrained non-linear brightness adjustment via Retinex theory. Integrated with FP16 mixed-precision computation and dynamic operator fusion, our method achieves millisecond-level inference for 4K/8K images on a single consumer-grade device, while outperforming state-of-the-art (SOTA) models on several restoration metrics.

SMCNet: Supervised Surface Material Classification Using mmWave Radar IQ Signals and Complex-valued CNNs

Understanding surface material properties is crucial for enhancing indoor robot perception and indoor digital twinning. However, not all sensor modalities typically employed for this task are capable of reliably capturing detailed surface material characteristics. By analyzing the reflected RF signal from a mmWave radar sensor, it is possible to extract information about the reflective material and its composition from a certain surface. We introduce a mmWave MIMO FMCW radar-based surface material classifier SMCNet, employing a complex-valued Convolutional Neural Network (CNN) and complex radar IQ signal input for classifying indoor surface materials. While current radar-based material estimation approaches rely on a fixed sensing distance and constrained setups, our approach incorporates a setup with multiple sensing distances. We trained SMCNet using data from three distinct distances and subsequently tested it on these distances, as well as on two more unseen distances. We reached an overall accuracy of 99.12-99.53 % on our test set. Notably, range FFT pre-processing improved accuracy on unknown distances from 25.25 % to 58.81 % without re-training.

CodaRAG: Connecting the Dots with Associativity Inspired by Complementary Learning

Large Language Models (LLMs) struggle with knowledge-intensive tasks due to hallucinations and fragmented reasoning over dispersed information. While Retrieval-Augmented Generation (RAG) grounds generation in external sources, existing methods often treat evidence as isolated units, failing to reconstruct the logical chains that connect these dots. Inspired by Complementary Learning Systems (CLS), we propose CodaRAG, a framework that evolves retrieval from passive lookup into active associative discovery. CodaRAG operates via a three-stage pipeline: (1) Knowledge Consolidation to unify fragmented extractions into a stable memory substrate; (2) Associative Navigation to traverse the graph via multi-dimensional pathways-semantic, contextualized, and functional-explicitly recovering dispersed evidence chains; and (3) Interference Elimination to prune hyper-associative noise, ensuring a coherent, high-precision reasoning context. On GraphRAG-Bench, CodaRAG achieves absolute gains of 7-10% in retrieval recall and 3-11% in generation accuracy. These results demonstrate CodaRAG's superior ability to systematically robustify associative evidence retrieval for factual, reasoning, and creative tasks.

Deep Learning-Based Physical Layer Authentication Using 5G NR Sounding Reference Signals: A Temporal Generalization Study on Real Testbed Data

Physical Layer Authentication (PLA) exploits the spatial uniqueness of wireless channel characteristics in order to authenticate devices without recourse to higher-layer cryptographic protocols, which remain vulnerable to key compromise. This paper reports a comprehensive PLA system constructed on 5G New Radio (NR) Sounding Reference Signals (SRS) extracted from a real OpenAirInterface (OAI) testbed operating in band n78 (3.5 GHz) with 40 MHz bandwidth and 30 kHz subcarrier spacing. The proposed approach extracts a 2,531-dimensional feature vector per SRS probe, combining per-subcarrier channel state information (1,248 amplitude and 1,247 differential-phase coefficients), power delay profile taps, delay spread, Doppler statistics, and nonlinear dynamics indicators. A deep one-dimensional Residual Network (1D-ResNet) augmented with Squeeze-and-Excitation (SE) attention blocks is employed to classify each probe as either legitimate or spoofed. Evaluation is conducted on 20,317 over-the-air SRS probes acquired across four measurement sessions using a USRP B210 software-defined radio as the legitimate device and a commercial mobile handset as the attacker. Under a strict chronological train/validation/test split that eliminates temporal leakage, an Equal Error Rate (EER) of 3.92% is attained, with AUC = 0.962 on the held-out test set, and an authentication latency of less than 0.1 ms per probe, which is compatible with 5G Ultra-Reliable Low-Latency Communications (URLLC) requirements.

KV Cache Offloading for Context-Intensive Tasks

With the growing demand for long-context LLMs across a wide range of applications, the key-value (KV) cache has become a critical bottleneck for both latency and memory usage. Recently, KV-cache offloading has emerged as a promising approach to reduce memory footprint and inference latency while preserving accuracy. Prior evaluations have largely focused on tasks that do not require extracting large amounts of information from the context. In this work, we study KV-cache offloading on context-intensive tasks: problems where the solution requires looking up a lot of information from the input prompt. We create and release the Text2JSON benchmark, a highly context-intensive task that requires extracting structured knowledge from raw text. We evaluate modern KV offloading on Text2JSON and other context-intensive tasks and find significant performance degradation on both Llama 3 and Qwen 3 models. Our analysis identifies two key reasons for poor accuracy: low-rank projection of keys and unreliable landmarks, and proposes a simpler alternative strategy that significantly improves accuracy across multiple LLM families and benchmarks. These findings highlight the need for a comprehensive and rigorous evaluation of long-context compression techniques.

At FullTilt: Real-Time Open-Set 3D Macromolecule Detection Directly from Tilted 2D Projections

Open-set 3D macromolecule detection in cryogenic electron tomography eliminates the need for target-specific model retraining. However, strict VRAM constraints prohibit processing an entire 3D tomogram, forcing current methods to rely on slow sliding-window inference over extracted subvolumes. To overcome this, we propose FullTilt, an end-to-end framework that redefines 3D detection by operating directly on aligned 2D tilt-series. Because a tilt-series contains significantly fewer images than slices in a reconstructed tomogram, FullTilt eliminates redundant volumetric computation, accelerating inference by orders of magnitude. To process the entire tilt-series simultaneously, we introduce a tilt-series encoder to efficiently fuse cross-view information. We further propose a multiclass visual prompt encoder for flexible prompting, a tilt-aware query initializer to effectively anchor 3D queries, and an auxiliary geometric primitives module to enhance the model's understanding of multi-view geometry while improving robustness to adverse imaging artifacts. Extensive evaluations on three real-world datasets demonstrate that FullTilt achieves state-of-the-art zero-shot performance while drastically reducing runtime and VRAM requirements, paving the way for rapid, large-scale visual proteomics analysis. All code and data will be publicly available upon publication.