MuDD: A Multimodal Deception Detection Dataset and GSR-Guided Progressive Distillation for Non-Contact Deception Detection

Non-contact automatic deception detection remains challenging because visual and auditory deception cues often lack stable cross-subject patterns. In contrast, galvanic skin response (GSR) provides more reliable physiological cues and has been widely used in contact-based deception detection. In this work, we leverage stable deception-related knowledge in GSR to guide representation learning in non-contact modalities through cross-modal knowledge distillation. A key obstacle, however, is the lack of a suitable dataset for this setting. To address this, we introduce MuDD, a large-scale Multimodal Deception Detection dataset containing recordings from 130 participants over 690 minutes. In addition to video, audio, and GSR, MuDD also provides Photoplethysmography, heart rate, and personality traits, supporting broader scientific studies of deception. Based on this dataset, we propose GSR-guided Progressive Distillation (GPD), a cross-modal distillation framework for mitigating the negative transfer caused by the large modality mismatch between GSR and non-contact signals. The core innovation of GPD is the integration of progressive feature-level and digit-level distillation with dynamic routing, which allows the model to adaptively determine how teacher knowledge should be transferred during training, leading to more stable cross-modal knowledge transfer. Extensive experiments and visualizations show that GPD outperforms existing methods and achieves state-of-the-art performance on both deception detection and concealed-digit identification.

MVRD-Bench: Multi-View Learning and Benchmarking for Dynamic Remote Photoplethysmography under Occlusion

Remote photoplethysmography (rPPG) is a non-contact technique that estimates physiological signals by analyzing subtle skin color changes in facial videos. Existing rPPG methods often encounter performance degradation under facial motion and occlusion scenarios due to their reliance on static and single-view facial videos. Thus, this work focuses on tackling the motion-induced occlusion problem for rPPG measurement in unconstrained multi-view facial videos. Specifically, we introduce a Multi-View rPPG Dataset (MVRD), a high-quality benchmark dataset featuring synchronized facial videos from three viewpoints under stationary, speaking, and head movement scenarios to better match real-world conditions. We also propose MVRD-rPPG, a unified multi-view rPPG learning framework that fuses complementary visual cues to maintain robust facial skin coverage, especially under motion conditions. Our method integrates an Adaptive Temporal Optical Compensation (ATOC) module for motion artifact suppression, a Rhythm-Visual Dual-Stream Network to disentangle rhythmic and appearance-related features, and a Multi-View Correlation-Aware Attention (MVCA) for adaptive view-wise signal aggregation. Furthermore, we introduce a Correlation Frequency Adversarial (CFA) learning strategy, which jointly enforces temporal accuracy, spectral consistency, and perceptual realism in the predicted signals. Extensive experiments and ablation studies on the MVRD dataset demonstrate the superiority of our approach. In the MVRD movement scenario, MVRD-rPPG achieves an MAE of 0.90 and a Pearson correlation coefficient (R) of 0.99. The source code and dataset will be made available.

Deriving Health Metrics from the Photoplethysmogram: Benchmarks and Insights from MIMIC-III-Ext-PPG

Photoplethysmography (PPG) is one of the most widely captured biosignals for clinical prediction tasks, yet PPG-based algorithms are typically trained on small-scale datasets of uncertain quality, which hinders meaningful algorithm comparisons. We present a comprehensive benchmark for PPG-based clinical prediction using the \dbname~dataset, establishing baselines across the full spectrum of clinically relevant applications: multi-class heart rhythm classification, and regression of physiological parameters including respiratory rate (RR), heart rate (HR), and blood pressure (BP). Most notably, we provide the first comprehensive assessment of PPG for general arrhythmia detection beyond atrial fibrillation (AF) and atrial flutter (AFLT), with performance stratified by BP, HR, and demographic subgroups. Using established deep learning architectures, we achieved strong performance for AF detection (AUROC = 0.96) and accurate physiological parameter estimation (RR MAE: 2.97 bpm; HR MAE: 1.13 bpm; SBP/DBP MAE: 16.13/8.70 mmHg). Cross-dataset validation demonstrates excellent generalizability for AF detection (AUROC = 0.97), while clinical subgroup analysis reveals marked performance differences across subgroups by BP, HR, and demographic strata. These variations appear to reflect population-specific waveform differences rather than systematic bias in model behavior. This framework establishes the first integrated benchmark for multi-task PPG-based clinical prediction, demonstrating that PPG signals can effectively support multiple simultaneous monitoring tasks and providing essential baselines for future algorithm development.

PhysNeXt: Next-Generation Dual-Branch Structured Attention Fusion Network for Remote Photoplethysmography Measurement

Remote photoplethysmography (rPPG) enables contactless measurement of heart rate and other vital signs by analyzing subtle color variations in facial skin induced by cardiac pulsation. Current rPPG methods are mainly based on either end-to-end modeling from raw videos or intermediate spatial-temporal map (STMap) representations. The former preserves complete spatiotemporal information and can capture subtle heartbeat-related signals, but it also introduces substantial noise from motion artifacts and illumination variations. The latter stacks the temporal color changes of multiple facial regions of interest into compact two-dimensional representations, significantly reducing data volume and computational complexity, although some high-frequency details may be lost. To effectively integrate the mutual strengths, we propose PhysNeXt, a dual-input deep learning framework that jointly exploits video frames and STMap representations. By incorporating a spatio-temporal difference modeling unit, a cross-modal interaction module, and a structured attention-based decoder, PhysNeXt collaboratively enhances the robustness of pulse signal extraction. Experimental results demonstrate that PhysNeXt achieves more stable and fine-grained rPPG signal recovery under challenging conditions, validating the effectiveness of joint modeling of video and STMap representations. The codes will be released.

VideoPulse: Neonatal heart rate and peripheral capillary oxygen saturation (SpO2) estimation from contact free video

Remote photoplethysmography (rPPG) enables contact free monitoring of vital signs and is especially valuable for neonates, since conventional methods often require sustained skin contact with adhesive probes that can irritate fragile skin and increase infection control burden. We present VideoPulse, a neonatal dataset and an end to end pipeline that estimates neonatal heart rate and peripheral capillary oxygen saturation (SpO2) from facial video. VideoPulse contains 157 recordings totaling 2.6 hours from 52 neonates with diverse face orientations. Our pipeline performs face alignment and artifact aware supervision using denoised pulse oximeter signals, then applies 3D CNN backbones for heart rate and SpO2 regression with label distribution smoothing and weighted regression for SpO2. Predictions are produced in 2 second windows. On the NBHR neonatal dataset, we obtain heart rate MAE 2.97 bpm using 2 second windows (2.80 bpm at 6 second windows) and SpO2 MAE 1.69 percent. Under cross dataset evaluation, the NBHR trained heart rate model attains 5.34 bpm MAE on VideoPulse, and fine tuning an NBHR pretrained SpO2 model on VideoPulse yields MAE 1.68 percent. These results indicate that short unaligned neonatal video segments can support accurate heart rate and SpO2 estimation, enabling low cost non invasive monitoring in neonatal intensive care.

Non-Contact Physiological Monitoring in Pediatric Intensive Care Units via Adaptive Masking and Self-Supervised Learning

Continuous monitoring of vital signs in Pediatric Intensive Care Units (PICUs) is essential for early detection of clinical deterioration and effective clinical decision-making. However, contact-based sensors such as pulse oximeters may cause skin irritation, increase infection risk, and lead to patient discomfort. Remote photoplethysmography (rPPG) offers a contactless alternative to monitor heart rate using facial video, but remains underutilized in PICUs due to motion artifacts, occlusions, variable lighting, and domain shifts between laboratory and clinical data. We introduce a self-supervised pretraining framework for rPPG estimation in the PICU setting, based on a progressive curriculum strategy. The approach leverages the VisionMamba architecture and integrates an adaptive masking mechanism, where a lightweight Mamba-based controller assigns spatiotemporal importance scores to guide probabilistic patch sampling. This strategy dynamically increases reconstruction difficulty while preserving physiological relevance. To address the lack of labeled clinical data, we adopt a teacher-student distillation setup. A supervised expert model, trained on public datasets, provides latent physiological guidance to the student. The curriculum progresses through three stages: clean public videos, synthetic occlusion scenarios, and unlabeled videos from 500 pediatric patients. Our framework achieves a 42% reduction in mean absolute error relative to standard masked autoencoders and outperforms PhysFormer by 31%, reaching a final MAE of 3.2 bpm. Without explicit region-of-interest extraction, the model consistently attends to pulse-rich areas and demonstrates robustness under clinical occlusions and noise.

In-Hospital Stroke Prediction from PPG-Derived Hemodynamic Features

The absence of pre-hospital physiological data in standard clinical datasets fundamentally constrains the early prediction of stroke, as patients typically present only after stroke has occurred, leaving the predictive value of continuous monitoring signals such as photoplethysmography (PPG) unvalidated. In this work, we overcome this limitation by focusing on a rare but clinically critical cohort - patients who suffered stroke during hospitalization while already under continuous monitoring - thereby enabling the first large-scale analysis of pre-stroke PPG waveforms aligned to verified onset times. Using MIMIC-III and MC-MED, we develop an LLM-assisted data mining pipeline to extract precise in-hospital stroke onset timestamps from unstructured clinical notes, followed by physician validation, identifying 176 patients (MIMIC) and 158 patients (MC-MED) with high-quality synchronized pre-onset PPG data, respectively. We then extract hemodynamic features from PPG and employ a ResNet-1D model to predict impending stroke across multiple early-warning horizons. The model achieves F1-scores of 0.7956, 0.8759, and 0.9406 at 4, 5, and 6 hours prior to onset on MIMIC-III, and, without re-tuning, reaches 0.9256, 0.9595, and 0.9888 on MC-MED for the same horizons. These results provide the first empirical evidence from real-world clinical data that PPG contains predictive signatures of stroke several hours before onset, demonstrating that passively acquired physiological signals can support reliable early warning, supporting a shift from post-event stroke recognition to proactive, physiology-based surveillance that may materially improve patient outcomes in routine clinical care.

Aortic Valve Disease Detection from PPG via Physiology-Informed Self-Supervised Learning

Traditional diagnosis of aortic valve disease relies on echocardiography, but its cost and required expertise limit its use in large-scale early screening. Photoplethysmography (PPG) has emerged as a promising screening modality due to its widespread availability in wearable devices and its ability to reflect underlying hemodynamic dynamics. However, the extreme scarcity of gold-standard labeled PPG data severely constrains the effectiveness of data-driven approaches. To address this challenge, we propose and validate a new paradigm, Physiology-Guided Self-Supervised Learning (PG-SSL), aimed at unlocking the value of large-scale unlabeled PPG data for efficient screening of Aortic Stenosis (AS) and Aortic Regurgitation (AR). Using over 170,000 unlabeled PPG samples from the UK Biobank, we formalize clinical knowledge into a set of PPG morphological phenotypes and construct a pulse pattern recognition proxy task for self-supervised pre-training. A dual-branch, gated-fusion architecture is then employed for efficient fine-tuning on a small labeled subset. The proposed PG-SSL framework achieves AUCs of 0.765 and 0.776 for AS and AR screening, respectively, significantly outperforming supervised baselines trained on limited labeled data. Multivariable analysis further validates the model output as an independent digital biomarker with sustained prognostic value after adjustment for standard clinical risk factors. This study demonstrates that PG-SSL provides an effective, domain knowledge-driven solution to label scarcity in medical artificial intelligence and shows strong potential for enabling low-cost, large-scale early screening of aortic valve disease.

Combining scEEG and PPG for reliable sleep staging using lightweight wearables

Reliable sleep staging remains challenging for lightweight wearable devices such as single-channel electroencephalography (scEEG) or photoplethysmography (PPG). scEEG offers direct measurement of cortical activity and serves as the foundation for sleep staging, yet exhibits limited performance on light sleep stages. PPG provides a low-cost complement that captures autonomic signatures effective for detecting light sleep. However, prior PPG-based methods rely on full night recordings (8 - 10 hours) as input context, which is less practical to provide timely feedback for sleep intervention. In this work, we investigate scEEG-PPG fusion for 4-class sleep staging under short-window (30 s - 30 min) constraints. First, we evaluate the temporal context required for each modality, to better understand the relationship of sleep staging performance with respect to monitoring window. Second, we investigate three fusion strategies: score-level fusion, cross-attention fusion enabling feature-level interactions, and Mamba-enhanced fusion incorporating temporal context modeling. Third, we train and evaluate on the Multi-Ethnic Study of Atherosclerosis (MESA) dataset and perform cross-dataset validation on the Cleveland Family Study (CFS) and the Apnea, Bariatric surgery, and CPAP (ABC) datasets. The Mamba-enhanced fusion achieves the best performance on MESA (Cohen's Kappa $κ$ = 0.798, Acc = 86.9%), with particularly notable improvement in light sleep classification (F1-score: 85.63% vs. 77.76%, recall: 82.85% vs. 69.95% for scEEG alone), and generalizes well to CFS and ABC datasets with different populations. These findings suggest that scEEG-PPG fusion is a promising approach for lightweight wearable based sleep monitoring, offering a pathway toward more accessible sleep health assessment. Source code of this project can be found at: https://github.com/DavyWJW/scEEG-PPGFusion

Benchmarking and Enhancing PPG-Based Cuffless Blood Pressure Estimation Methods

Cuffless blood pressure screening based on easily acquired photoplethysmography (PPG) signals offers a practical pathway toward scalable cardiovascular health assessment. Despite rapid progress, existing PPG-based blood pressure estimation models have not consistently achieved the established clinical numerical limits such as AAMI/ISO 81060-2, and prior evaluations often lack the rigorous experimental controls necessary for valid clinical assessment. Moreover, the publicly available datasets commonly used are heterogeneous and lack physiologically controlled conditions for fair benchmarking. To enable fair benchmarking under physiologically controlled conditions, we created a standardized benchmarking subset NBPDB comprising 101,453 high-quality PPG segments from 1,103 healthy adults, derived from MIMIC-III and VitalDB. Using this dataset, we systematically benchmarked several state-of-the-art PPG-based models. The results showed that none of the evaluated models met the AAMI/ISO 81060-2 accuracy requirements (mean error $<$ 5 mmHg and standard deviation $<$ 8 mmHg). To improve model accuracy, we modified these models and added patient demographic data such as age, sex, and body mass index as additional inputs. Our modifications consistently improved performance across all models. In particular, the MInception model reduced error by 23\% after adding the demographic data and yielded mean absolute errors of 4.75 mmHg (SBP) and 2.90 mmHg (DBP), achieves accuracy comparable to the numerical limits defined by AAMI/ISO accuracy standards. Our results show that existing PPG-based BP estimation models lack clinical practicality under standardized conditions, while incorporating demographic information markedly improves their accuracy and physiological validity.