Abstract:A data-driven, model-free approach to modeling the temporal evolution of physical systems mitigates the need for explicit knowledge of the governing equations. Even when physical priors such as partial differential equations are available, such systems often reside in high-dimensional state spaces and exhibit nonlinear dynamics, making traditional numerical solvers computationally expensive and ill-suited for real-time analysis and control. Consider the problem of learning a parametric flow of a dynamical system: with an initial field and a set of physical parameters, we aim to predict the system's evolution over time in a way that supports long-horizon rollouts, generalization to unseen parameters, and spectral analysis. We propose a physics-coded neural field parameterization of the Koopman operator's spectral decomposition. Unlike a physics-constrained neural field, which fits a single solution surface, and neural operators, which directly approximate the solution operator at fixed time horizons, our model learns a factorized flow operator that decouples spatial modes and temporal evolution. This structure exposes underlying eigenvalues, modes, and stability of the underlying physical process to enable stable long-term rollouts, interpolation across parameter spaces, and spectral analysis. We demonstrate the efficacy of our method on a range of dynamics problems, showcasing its ability to accurately predict complex spatiotemporal phenomena while providing insights into the system's dynamic behavior.
Abstract:3D-aware visual pretraining has proven effective in improving the performance of downstream robotic manipulation tasks. However, existing methods are constrained to Euclidean embedding spaces, whose flat geometry limits their ability to model structural relations among embeddings. As a result, they struggle to learn structured embeddings that are essential for robust spatial perception in robotic applications. To this end, we propose HyperMVP, a self-supervised framework for \underline{Hyper}bolic \underline{M}ulti\underline{V}iew \underline{P}retraining. Hyperbolic space offers geometric properties well suited for capturing structural relations. Methodologically, we extend the masked autoencoder paradigm and design a GeoLink encoder to learn multiview hyperbolic representations. The pretrained encoder is then finetuned with visuomotor policies on manipulation tasks. In addition, we introduce 3D-MOV, a large-scale dataset comprising multiple types of 3D point clouds to support pretraining. We evaluate HyperMVP on COLOSSEUM, RLBench, and real-world scenarios, where it consistently outperforms strong baselines across diverse tasks and perturbation settings. Our results highlight the potential of 3D-aware pretraining in a non-Euclidean space for learning robust and generalizable robotic manipulation policies.
Abstract:Pathology report generation remains a relatively under-explored downstream task, primarily due to the gigapixel scale and complex morphological heterogeneity of Whole Slide Images (WSIs). Existing pathology report generation frameworks typically employ transformer architectures, relying on a homogeneous decoder architecture and static knowledge retrieval integration. Such architectures limit generative specialization and may introduce noisy external guidance during the report generation process. To address these limitations, we propose RANGER, a sparsely-gated Mixture-of-Experts (MoE) framework with adaptive retrieval re-ranking for pathology report generation. Specifically, we integrate a sparsely gated MoE into the decoder, along with noisy top-$k$ routing and load-balancing regularization, to enable dynamic expert specialization across various diagnostic patterns. Additionally, we introduce an adaptive retrieval re-ranking module that selectively refines retrieved memory from a knowledge base before integration, reducing noise and improving semantic alignment based on visual feature representations. We perform extensive experiments on the PathText-BRCA dataset and demonstrate consistent improvements over existing approaches across standard natural language generation metrics. Our full RANGER model achieves optimal performance on PathText dataset, reaching BLEU-1 to BLEU-4 scores of 0.4598, 0.3044, 0.2036, and 0.1435, respectively, with METEOR of 0.1883, and ROUGE-L of 0.3038, validating the effectiveness of dynamic expert routing and adaptive knowledge refinement for semantically grounded pathology report generation.
Abstract:Preoperative improvement rate prediction for Parkinson's disease surgery is clinically important yet difficult because imaging signals are subtle and patients are heterogeneous. We address this setting, where only information available before surgery is used, and the goal is to predict patient-specific postoperative motor benefit. We present PreSight, a presurgical outcome model that fuses clinical priors with preoperative MRI and deformation-based morphometry (DBM) and adapts regional importance through a patient-specific weighting module. The model produces end-to-end, calibrated, decision-ready predictions with patient-level explanations. We evaluate PreSight on a real-world two-center cohort of 400 subjects with multimodal presurgical inputs and postoperative improvement labels. PreSight outperforms strong clinical, imaging-only, and multimodal baselines. It attains 88.89% accuracy on internal validation and 85.29% on an external-center test for responder classification and shows better probability calibration and higher decision-curve net benefit. Ablations and analyses confirm the contribution of DBM and the patient-specific weighting module and indicate that the model emphasizes disease-relevant regions in a patient-specific manner. These results demonstrate that integrating clinical prior knowledge with region-adaptive morphometry enables reliable presurgical decision support in routine practice.
Abstract:Synthetic tabular data generation has attracted growing attention due to its importance for data augmentation, foundation models, and privacy. However, real-world tabular datasets increasingly contain free-form text fields (e.g., reviews or clinical notes) alongside structured numerical and categorical attributes. Generating such heterogeneous tables with joint modeling of different modalities remains challenging. Existing approaches broadly fall into two categories: diffusion-based methods and LLM-based methods. Diffusion models can capture complex dependencies over numerical and categorical features in continuous or discrete spaces, but extending them to open-ended text is nontrivial and often leads to degraded text quality. In contrast, LLM-based generators naturally produce fluent text, yet their discrete tokenization can distort precise or wide-range numerical values, hindering accurate modeling of both numbers and language. In this work, we propose TabDLM, a unified framework for free-form tabular data generation via a joint numerical--language diffusion model built on masked diffusion language models (MDLMs). TabDLM models textual and categorical features through masked diffusion, while modeling numerical features with a continuous diffusion process through learned specialized numeric tokens embedding; bidirectional attention then captures cross-modality interactions within a single model. Extensive experiments on diverse benchmarks demonstrate the effectiveness of TabDLM compared to strong diffusion- and LLM-based baselines.
Abstract:Retrieval-augmented generation (RAG) has become a dominant paradigm for grounding large language models (LLMs) with external evidence in knowledge-intensive question answering. A core design choice is how to fuse retrieved samples into the LLMs, where existing internal fusion approaches broadly fall into query-based fusion, parametric fusion, and latent-based fusion. Despite their effectiveness at modest retrieval scales, these methods often fail to scale gracefully as the number of retrieved candidates k increases: Larger k improves evidence coverage, yet realistic top-k retrieval inevitably contains irrelevant or redundant content and increases the inference cost. To address these limitations, we propose ReFilter, a novel latent-based fusion framework that performs token-level filtering and fusion. ReFilter consists of three key components: a context encoder for encoding context features, a gated filter for weighting each token, and a token fusion module for integrating the weighted token feature into the LLM's hidden states. Our experiments across four general-domain QA benchmarks show that ReFilter consistently achieves the best average performance under both in-domain adaptation and out-of-domain transfer. ReFilter further generalizes to five biomedical QA benchmarks in zero-shot transfer without domain fine-tuning, reaching 70.01% average accuracy with Qwen2.5-14B-Instruct.
Abstract:Metastatic Progression remains the leading cause of cancer-related mortality, yet predicting whether a primary tumor will metastasize and where it will disseminate directly from histopathology remains a fundamental challenge. Although whole-slide images (WSIs) provide rich morphological information, prior computational pathology approaches typically address metastatic status or site prediction as isolated tasks, and do not explicitly model the clinically sequential decision process of metastatic risk assessment followed by downstream site-specific evaluation. To address this research gap, we present a decision-aware, concept-aligned MIL framework, HistoMet, for prognostic metastatic outcome prediction from primary tumor WSIs. Our proposed framework adopts a two-module prediction pipeline in which the likelihood of metastatic progression from the primary tumor is first estimated, followed by conditional prediction of metastatic site for high-risk cases. To guide representation learning and improve clinical interpretability, our framework integrates linguistically defined and data-adaptive metastatic concepts through a pretrained pathology vision-language model. We evaluate HistoMet on a multi-institutional pan-cancer cohort of 6504 patients with metastasis follow-up and site annotations. Under clinically relevant high-sensitivity screening settings (95 percent sensitivity), HistoMet significantly reduces downstream workload while maintaining high metastatic risk recall. Conditional on metastatic cases, HistoMet achieves a macro F1 of 74.6 with a standard deviation of 1.3 and a macro one-vs-rest AUC of 92.1. These results demonstrate that explicitly modeling clinical decision structure enables robust and deployable prognostic prediction of metastatic progression and site tropism directly from primary tumor histopathology.
Abstract:3D Gaussian Splatting (3DGS) has emerged as a prominent 3D representation for high-fidelity and real-time rendering. Prior work has coupled physics simulation with Gaussians, but predominantly targets soft, deformable materials, leaving brittle fracture largely unresolved. This stems from two key obstacles: the lack of volumetric interiors with coherent textures in GS representation, and the absence of fracture-aware simulation methods for Gaussians. To address these challenges, we introduce GaussianFluent, a unified framework for realistic simulation and rendering of dynamic object states. First, it synthesizes photorealistic interiors by densifying internal Gaussians guided by generative models. Second, it integrates an optimized Continuum Damage Material Point Method (CD-MPM) to enable brittle fracture simulation at remarkably high speed. Our approach handles complex scenarios including mixed-material objects and multi-stage fracture propagation, achieving results infeasible with previous methods. Experiments clearly demonstrate GaussianFluent's capability for photo-realistic, real-time rendering with structurally consistent interiors, highlighting its potential for downstream application, such as VR and Robotics.
Abstract:We introduce SciEvalKit, a unified benchmarking toolkit designed to evaluate AI models for science across a broad range of scientific disciplines and task capabilities. Unlike general-purpose evaluation platforms, SciEvalKit focuses on the core competencies of scientific intelligence, including Scientific Multimodal Perception, Scientific Multimodal Reasoning, Scientific Multimodal Understanding, Scientific Symbolic Reasoning, Scientific Code Generation, Science Hypothesis Generation and Scientific Knowledge Understanding. It supports six major scientific domains, spanning from physics and chemistry to astronomy and materials science. SciEvalKit builds a foundation of expert-grade scientific benchmarks, curated from real-world, domain-specific datasets, ensuring that tasks reflect authentic scientific challenges. The toolkit features a flexible, extensible evaluation pipeline that enables batch evaluation across models and datasets, supports custom model and dataset integration, and provides transparent, reproducible, and comparable results. By bridging capability-based evaluation and disciplinary diversity, SciEvalKit offers a standardized yet customizable infrastructure to benchmark the next generation of scientific foundation models and intelligent agents. The toolkit is open-sourced and actively maintained to foster community-driven development and progress in AI4Science.
Abstract:Change detection plays a vital role in scene monitoring, exploration, and continual reconstruction. Existing 3D change detection methods often exhibit spatial inconsistency in the detected changes and fail to explicitly separate pre- and post-change states. To address these limitations, we propose SCaR-3D, a novel 3D scene change detection framework that identifies object-level changes from a dense-view pre-change image sequence and sparse-view post-change images. Our approach consists of a signed-distance-based 2D differencing module followed by multi-view aggregation with voting and pruning, leveraging the consistent nature of 3DGS to robustly separate pre- and post-change states. We further develop a continual scene reconstruction strategy that selectively updates dynamic regions while preserving the unchanged areas. We also contribute CCS3D, a challenging synthetic dataset that allows flexible combinations of 3D change types to support controlled evaluations. Extensive experiments demonstrate that our method achieves both high accuracy and efficiency, outperforming existing methods.