Visual Instruction Tuning with Chain of Region-of-Interest

High-resolution (HR) images are pivotal for enhancing the recognition and understanding capabilities of multimodal large language models (MLLMs). However, directly increasing image resolution can significantly escalate computational demands. In this study, we propose a method called Chain of Region-of-Interest (CoRoI) for Visual Instruction Tuning, aimed at alleviating the computational burden associated with high-resolution images for MLLMs. Drawing inspiration from the selective nature of the human visual system, we recognize that not all regions within high-resolution images carry equal importance. CoRoI seeks to identify and prioritize the most informative regions, thereby enhancing multimodal visual comprehension and recognition while circumventing the need for processing lengthy HR image tokens. Through extensive experiments on 11 benchmarks, we validate the efficacy of CoRoI across varying sizes, ranging from 7B to 34B in parameters. Our models consistently demonstrate superior performance across diverse multimodal benchmarks and tasks. Notably, our method outperforms LLaVA-NeXT on almost all benchmarks and our finetuned 34B model surpasses proprietary methods like Gemini Pro 1.0 on six benchmarks, as well as outperforming GPT-4V on MMB, SEED-I, and MME.

MetaScenes: Towards Automated Replica Creation for Real-world 3D Scans

Embodied AI (EAI) research requires high-quality, diverse 3D scenes to effectively support skill acquisition, sim-to-real transfer, and generalization. Achieving these quality standards, however, necessitates the precise replication of real-world object diversity. Existing datasets demonstrate that this process heavily relies on artist-driven designs, which demand substantial human effort and present significant scalability challenges. To scalably produce realistic and interactive 3D scenes, we first present MetaScenes, a large-scale, simulatable 3D scene dataset constructed from real-world scans, which includes 15366 objects spanning 831 fine-grained categories. Then, we introduce Scan2Sim, a robust multi-modal alignment model, which enables the automated, high-quality replacement of assets, thereby eliminating the reliance on artist-driven designs for scaling 3D scenes. We further propose two benchmarks to evaluate MetaScenes: a detailed scene synthesis task focused on small item layouts for robotic manipulation and a domain transfer task in vision-and-language navigation (VLN) to validate cross-domain transfer. Results confirm MetaScene's potential to enhance EAI by supporting more generalizable agent learning and sim-to-real applications, introducing new possibilities for EAI research. Project website: https://meta-scenes.github.io/.

Flexible Graph Similarity Computation With A Proactive Optimization Strategy

Graph Edit Distance (GED) is an important similarity measure in graph retrieval, which quantifies the minimum cost of transforming one graph into another through edit operations, and offers flexibility by allowing customizable operation costs. Recent learning-based approaches approximate GEDs with the distances between representations in vector spaces. However, these methods often struggle with varying operation costs due to neglecting the impact of these costs on determining optimal graph mappings. Furthermore, they rely on isolated node distances as guidance, necessitating inefficient reactive refinements of mappings. To address these issues, we propose Graph Edit Network (GEN), a novel learning-based approach for flexible GED computation. By identifying the limitations of existing methods in capturing flexibility of GED, we introduce a principled yet simple solution that incorporates the operation costs before establishing mappings. To improve matching efficiency, we propose a strategy that proactively optimizes guidance from a graph perspective. This strategy initializes guidance as each node's alignment difficulty and captures the interdependencies between matches within and across graphs through a difficulty propagation mechanism, enabling more informed decisions. As a result, GEN selects optimal matches in a single step, minimizing the need for costly refinements. Results on real-world and synthetic datasets demonstrate the effectiveness, time efficiency, and adaptability of GEN, achieving up to 37.8\% error reduction and 72.7\% inference time reduction compared with state-of-the-art models, while performing robustly under varying cost settings and graph sizes.

OmniCellTOSG: The First Cell Text-Omic Signaling Graphs Dataset for Joint LLM and GNN Modeling

Complex cell signaling systems -- governed by varying protein abundances and interactions -- generate diverse cell types across organs. These systems evolve under influences such as age, sex, diet, environmental exposures, and diseases, making them challenging to decode given the involvement of tens of thousands of genes and proteins. Recently, hundreds of millions of single-cell omics data have provided a robust foundation for understanding these signaling networks within various cell subpopulations and conditions. Inspired by the success of large foundation models (for example, large language models and large vision models) pre-trained on massive datasets, we introduce OmniCellTOSG, the first dataset of cell text-omic signaling graphs (TOSGs). Each TOSG represents the signaling network of an individual or meta-cell and is labeled with information such as organ, disease, sex, age, and cell subtype. OmniCellTOSG offers two key contributions. First, it introduces a novel graph model that integrates human-readable annotations -- such as biological functions, cellular locations, signaling pathways, related diseases, and drugs -- with quantitative gene and protein abundance data, enabling graph reasoning to decode cell signaling. This approach calls for new joint models combining large language models and graph neural networks. Second, the dataset is built from single-cell RNA sequencing data of approximately 120 million cells from diverse tissues and conditions (healthy and diseased) and is fully compatible with PyTorch. This facilitates the development of innovative cell signaling models that could transform research in life sciences, healthcare, and precision medicine. The OmniCellTOSG dataset is continuously expanding and will be updated regularly. The dataset and code are available at https://github.com/FuhaiLiAiLab/OmniCellTOSG.

Dynamic Motion Blending for Versatile Motion Editing

Text-guided motion editing enables high-level semantic control and iterative modifications beyond traditional keyframe animation. Existing methods rely on limited pre-collected training triplets, which severely hinders their versatility in diverse editing scenarios. We introduce MotionCutMix, an online data augmentation technique that dynamically generates training triplets by blending body part motions based on input text. While MotionCutMix effectively expands the training distribution, the compositional nature introduces increased randomness and potential body part incoordination. To model such a rich distribution, we present MotionReFit, an auto-regressive diffusion model with a motion coordinator. The auto-regressive architecture facilitates learning by decomposing long sequences, while the motion coordinator mitigates the artifacts of motion composition. Our method handles both spatial and temporal motion edits directly from high-level human instructions, without relying on additional specifications or Large Language Models. Through extensive experiments, we show that MotionReFit achieves state-of-the-art performance in text-guided motion editing.

Decompositional Neural Scene Reconstruction with Generative Diffusion Prior

Decompositional reconstruction of 3D scenes, with complete shapes and detailed texture of all objects within, is intriguing for downstream applications but remains challenging, particularly with sparse views as input. Recent approaches incorporate semantic or geometric regularization to address this issue, but they suffer significant degradation in underconstrained areas and fail to recover occluded regions. We argue that the key to solving this problem lies in supplementing missing information for these areas. To this end, we propose DP-Recon, which employs diffusion priors in the form of Score Distillation Sampling (SDS) to optimize the neural representation of each individual object under novel views. This provides additional information for the underconstrained areas, but directly incorporating diffusion prior raises potential conflicts between the reconstruction and generative guidance. Therefore, we further introduce a visibility-guided approach to dynamically adjust the per-pixel SDS loss weights. Together these components enhance both geometry and appearance recovery while remaining faithful to input images. Extensive experiments across Replica and ScanNet++ demonstrate that our method significantly outperforms SOTA methods. Notably, it achieves better object reconstruction under 10 views than the baselines under 100 views. Our method enables seamless text-based editing for geometry and appearance through SDS optimization and produces decomposed object meshes with detailed UV maps that support photorealistic Visual effects (VFX) editing. The project page is available at https://dp-recon.github.io/.

KoGNER: A Novel Framework for Knowledge Graph Distillation on Biomedical Named Entity Recognition

Named Entity Recognition (NER) is a fundamental task in Natural Language Processing (NLP) that plays a crucial role in information extraction, question answering, and knowledge-based systems. Traditional deep learning-based NER models often struggle with domain-specific generalization and suffer from data sparsity issues. In this work, we introduce Knowledge Graph distilled for Named Entity Recognition (KoGNER), a novel approach that integrates Knowledge Graph (KG) distillation into NER models to enhance entity recognition performance. Our framework leverages structured knowledge representations from KGs to enrich contextual embeddings, thereby improving entity classification and reducing ambiguity in entity detection. KoGNER employs a two-step process: (1) Knowledge Distillation, where external knowledge sources are distilled into a lightweight representation for seamless integration with NER models, and (2) Entity-Aware Augmentation, which integrates contextual embeddings that have been enriched with knowledge graph information directly into GNN, thereby improving the model's ability to understand and represent entity relationships. Experimental results on benchmark datasets demonstrate that KoGNER achieves state-of-the-art performance, outperforming finetuned NER models and LLMs by a significant margin. These findings suggest that leveraging knowledge graphs as auxiliary information can significantly improve NER accuracy, making KoGNER a promising direction for future research in knowledge-aware NLP.

TACO: Taming Diffusion for in-the-wild Video Amodal Completion

Humans can infer complete shapes and appearances of objects from limited visual cues, relying on extensive prior knowledge of the physical world. However, completing partially observable objects while ensuring consistency across video frames remains challenging for existing models, especially for unstructured, in-the-wild videos. This paper tackles the task of Video Amodal Completion (VAC), which aims to generate the complete object consistently throughout the video given a visual prompt specifying the object of interest. Leveraging the rich, consistent manifolds learned by pre-trained video diffusion models, we propose a conditional diffusion model, TACO, that repurposes these manifolds for VAC. To enable its effective and robust generalization to challenging in-the-wild scenarios, we curate a large-scale synthetic dataset with multiple difficulty levels by systematically imposing occlusions onto un-occluded videos. Building on this, we devise a progressive fine-tuning paradigm that starts with simpler recovery tasks and gradually advances to more complex ones. We demonstrate TACO's versatility on a wide range of in-the-wild videos from Internet, as well as on diverse, unseen datasets commonly used in autonomous driving, robotic manipulation, and scene understanding. Moreover, we show that TACO can be effectively applied to various downstream tasks like object reconstruction and pose estimation, highlighting its potential to facilitate physical world understanding and reasoning. Our project page is available at https://jason-aplp.github.io/TACO.

Modality-Projection Universal Model for Comprehensive Full-Body Medical Imaging Segmentation

The integration of deep learning in medical imaging has shown great promise for enhancing diagnostic, therapeutic, and research outcomes. However, applying universal models across multiple modalities remains challenging due to the inherent variability in data characteristics. This study aims to introduce and evaluate a Modality Projection Universal Model (MPUM). MPUM employs a novel modality-projection strategy, which allows the model to dynamically adjust its parameters to optimize performance across different imaging modalities. The MPUM demonstrated superior accuracy in identifying anatomical structures, enabling precise quantification for improved clinical decision-making. It also identifies metabolic associations within the brain-body axis, advancing research on brain-body physiological correlations. Furthermore, MPUM's unique controller-based convolution layer enables visualization of saliency maps across all network layers, significantly enhancing the model's interpretability.

GraphSeqLM: A Unified Graph Language Framework for Omic Graph Learning

The integration of multi-omic data is pivotal for understanding complex diseases, but its high dimensionality and noise present significant challenges. Graph Neural Networks (GNNs) offer a robust framework for analyzing large-scale signaling pathways and protein-protein interaction networks, yet they face limitations in expressivity when capturing intricate biological relationships. To address this, we propose Graph Sequence Language Model (GraphSeqLM), a framework that enhances GNNs with biological sequence embeddings generated by Large Language Models (LLMs). These embeddings encode structural and biological properties of DNA, RNA, and proteins, augmenting GNNs with enriched features for analyzing sample-specific multi-omic data. By integrating topological, sequence-derived, and biological information, GraphSeqLM demonstrates superior predictive accuracy and outperforms existing methods, paving the way for more effective multi-omic data integration in precision medicine.