OMGs: A multi-agent system supporting MDT decision-making across the ovarian tumour care continuum

Ovarian tumour management has increasingly relied on multidisciplinary tumour board (MDT) deliberation to address treatment complexity and disease heterogeneity. However, most patients worldwide lack access to timely expert consensus, particularly in resource-constrained centres where MDT resources are scarce or unavailable. Here we present OMGs (Ovarian tumour Multidisciplinary intelligent aGent System), a multi-agent AI framework where domain-specific agents deliberate collaboratively to integrate multidisciplinary evidence and generate MDT-style recommendations with transparent rationales. To systematically evaluate MDT recommendation quality, we developed SPEAR (Safety, Personalization, Evidence, Actionability, Robustness) and validated OMGs across diverse clinical scenarios spanning the care continuum. In multicentre re-evaluation, OMGs achieved performance comparable to expert MDT consensus ($4.45 \pm 0.30$ versus $4.53 \pm 0.23$), with higher Evidence scores (4.57 versus 3.92). In prospective multicentre evaluation (59 patients), OMGs demonstrated high concordance with routine MDT decisions. Critically, in paired human-AI studies, OMGs most substantially enhanced clinicians' recommendations in Evidence and Robustness, the dimensions most compromised when multidisciplinary expertise is unavailable. These findings suggest that multi-agent deliberative systems can achieve performance comparable to expert MDT consensus, with potential to expand access to specialized oncology expertise in resource-limited settings.

OpenVTON-Bench: A Large-Scale High-Resolution Benchmark for Controllable Virtual Try-On Evaluation

Recent advances in diffusion models have significantly elevated the visual fidelity of Virtual Try-On (VTON) systems, yet reliable evaluation remains a persistent bottleneck. Traditional metrics struggle to quantify fine-grained texture details and semantic consistency, while existing datasets fail to meet commercial standards in scale and diversity. We present OpenVTON-Bench, a large-scale benchmark comprising approximately 100K high-resolution image pairs (up to $1536 \times 1536$). The dataset is constructed using DINOv3-based hierarchical clustering for semantically balanced sampling and Gemini-powered dense captioning, ensuring a uniform distribution across 20 fine-grained garment categories. To support reliable evaluation, we propose a multi-modal protocol that measures VTON quality along five interpretable dimensions: background consistency, identity fidelity, texture fidelity, shape plausibility, and overall realism. The protocol integrates VLM-based semantic reasoning with a novel Multi-Scale Representation Metric based on SAM3 segmentation and morphological erosion, enabling the separation of boundary alignment errors from internal texture artifacts. Experimental results show strong agreement with human judgments (Kendall's $τ$ of 0.833 vs. 0.611 for SSIM), establishing a robust benchmark for VTON evaluation.

Adaptive Exponential Integration for Stable Gaussian Mixture Black-Box Variational Inference

Black-box variational inference (BBVI) with Gaussian mixture families offers a flexible approach for approximating complex posterior distributions without requiring gradients of the target density. However, standard numerical optimization methods often suffer from instability and inefficiency. We develop a stable and efficient framework that combines three key components: (1) affine-invariant preconditioning via natural gradient formulations, (2) an exponential integrator that unconditionally preserves the positive definiteness of covariance matrices, and (3) adaptive time stepping to ensure stability and to accommodate distinct warm-up and convergence phases. The proposed approach has natural connections to manifold optimization and mirror descent. For Gaussian posteriors, we prove exponential convergence in the noise-free setting and almost-sure convergence under Monte Carlo estimation, rigorously justifying the necessity of adaptive time stepping. Numerical experiments on multimodal distributions, Neal's multiscale funnel, and a PDE-based Bayesian inverse problem for Darcy flow demonstrate the effectiveness of the proposed method.

POCI-Diff: Position Objects Consistently and Interactively with 3D-Layout Guided Diffusion

We propose a diffusion-based approach for Text-to-Image (T2I) generation with consistent and interactive 3D layout control and editing. While prior methods improve spatial adherence using 2D cues or iterative copy-warp-paste strategies, they often distort object geometry and fail to preserve consistency across edits. To address these limitations, we introduce a framework for Positioning Objects Consistently and Interactively (POCI-Diff), a novel formulation for jointly enforcing 3D geometric constraints and instance-level semantic binding within a unified diffusion process. Our method enables explicit per-object semantic control by binding individual text descriptions to specific 3D bounding boxes through Blended Latent Diffusion, allowing one-shot synthesis of complex multi-object scenes. We further propose a warping-free generative editing pipeline that supports object insertion, removal, and transformation via regeneration rather than pixel deformation. To preserve object identity and consistency across edits, we condition the diffusion process on reference images using IP-Adapter, enabling coherent object appearance throughout interactive 3D editing while maintaining global scene coherence. Experimental results demonstrate that POCI-Diff produces high-quality images consistent with the specified 3D layouts and edits, outperforming state-of-the-art methods in both visual fidelity and layout adherence while eliminating warping-induced geometric artifacts.

CoV: Chain-of-View Prompting for Spatial Reasoning

Embodied question answering (EQA) in 3D environments often requires collecting context that is distributed across multiple viewpoints and partially occluded. However, most recent vision--language models (VLMs) are constrained to a fixed and finite set of input views, which limits their ability to acquire question-relevant context at inference time and hinders complex spatial reasoning. We propose Chain-of-View (CoV) prompting, a training-free, test-time reasoning framework that transforms a VLM into an active viewpoint reasoner through a coarse-to-fine exploration process. CoV first employs a View Selection agent to filter redundant frames and identify question-aligned anchor views. It then performs fine-grained view adjustment by interleaving iterative reasoning with discrete camera actions, obtaining new observations from the underlying 3D scene representation until sufficient context is gathered or a step budget is reached. We evaluate CoV on OpenEQA across four mainstream VLMs and obtain an average +11.56\% improvement in LLM-Match, with a maximum gain of +13.62\% on Qwen3-VL-Flash. CoV further exhibits test-time scaling: increasing the minimum action budget yields an additional +2.51\% average improvement, peaking at +3.73\% on Gemini-2.5-Flash. On ScanQA and SQA3D, CoV delivers strong performance (e.g., 116 CIDEr / 31.9 EM@1 on ScanQA and 51.1 EM@1 on SQA3D). Overall, these results suggest that question-aligned view selection coupled with open-view search is an effective, model-agnostic strategy for improving spatial reasoning in 3D EQA without additional training.

In defense of the two-stage framework for open-set domain adaptive semantic segmentation

Open-Set Domain Adaptation for Semantic Segmentation (OSDA-SS) presents a significant challenge, as it requires both domain adaptation for known classes and the distinction of unknowns. Existing methods attempt to address both tasks within a single unified stage. We question this design, as the annotation imbalance between known and unknown classes often leads to negative transfer of known classes and underfitting for unknowns. To overcome these issues, we propose SATS, a Separating-then-Adapting Training Strategy, which addresses OSDA-SS through two sequential steps: known/unknown separation and unknown-aware domain adaptation. By providing the model with more accurate and well-aligned unknown classes, our method ensures a balanced learning of discriminative features for both known and unknown classes, steering the model toward discovering truly unknown objects. Additionally, we present hard unknown exploration, an innovative data augmentation method that exposes the model to more challenging unknowns, strengthening its ability to capture more comprehensive understanding of target unknowns. We evaluate our method on public OSDA-SS benchmarks. Experimental results demonstrate that our method achieves a substantial advancement, with a +3.85% H-Score improvement for GTA5-to-Cityscapes and +18.64% for SYNTHIA-to-Cityscapes, outperforming previous state-of-the-art methods.

Organ-Agents: Virtual Human Physiology Simulator via LLMs

Recent advances in large language models (LLMs) have enabled new possibilities in simulating complex physiological systems. We introduce Organ-Agents, a multi-agent framework that simulates human physiology via LLM-driven agents. Each Simulator models a specific system (e.g., cardiovascular, renal, immune). Training consists of supervised fine-tuning on system-specific time-series data, followed by reinforcement-guided coordination using dynamic reference selection and error correction. We curated data from 7,134 sepsis patients and 7,895 controls, generating high-resolution trajectories across 9 systems and 125 variables. Organ-Agents achieved high simulation accuracy on 4,509 held-out patients, with per-system MSEs <0.16 and robustness across SOFA-based severity strata. External validation on 22,689 ICU patients from two hospitals showed moderate degradation under distribution shifts with stable simulation. Organ-Agents faithfully reproduces critical multi-system events (e.g., hypotension, hyperlactatemia, hypoxemia) with coherent timing and phase progression. Evaluation by 15 critical care physicians confirmed realism and physiological plausibility (mean Likert ratings 3.9 and 3.7). Organ-Agents also enables counterfactual simulations under alternative sepsis treatment strategies, generating trajectories and APACHE II scores aligned with matched real-world patients. In downstream early warning tasks, classifiers trained on synthetic data showed minimal AUROC drops (<0.04), indicating preserved decision-relevant patterns. These results position Organ-Agents as a credible, interpretable, and generalizable digital twin for precision diagnosis, treatment simulation, and hypothesis testing in critical care.

INTENTION: Inferring Tendencies of Humanoid Robot Motion Through Interactive Intuition and Grounded VLM

Traditional control and planning for robotic manipulation heavily rely on precise physical models and predefined action sequences. While effective in structured environments, such approaches often fail in real-world scenarios due to modeling inaccuracies and struggle to generalize to novel tasks. In contrast, humans intuitively interact with their surroundings, demonstrating remarkable adaptability, making efficient decisions through implicit physical understanding. In this work, we propose INTENTION, a novel framework enabling robots with learned interactive intuition and autonomous manipulation in diverse scenarios, by integrating Vision-Language Models (VLMs) based scene reasoning with interaction-driven memory. We introduce Memory Graph to record scenes from previous task interactions which embodies human-like understanding and decision-making about different tasks in real world. Meanwhile, we design an Intuitive Perceptor that extracts physical relations and affordances from visual scenes. Together, these components empower robots to infer appropriate interaction behaviors in new scenes without relying on repetitive instructions. Videos: https://robo-intention.github.io

Learning to Recover: Dynamic Reward Shaping with Wheel-Leg Coordination for Fallen Robots

Adaptive recovery from fall incidents are essential skills for the practical deployment of wheeled-legged robots, which uniquely combine the agility of legs with the speed of wheels for rapid recovery. However, traditional methods relying on preplanned recovery motions, simplified dynamics or sparse rewards often fail to produce robust recovery policies. This paper presents a learning-based framework integrating Episode-based Dynamic Reward Shaping and curriculum learning, which dynamically balances exploration of diverse recovery maneuvers with precise posture refinement. An asymmetric actor-critic architecture accelerates training by leveraging privileged information in simulation, while noise-injected observations enhance robustness against uncertainties. We further demonstrate that synergistic wheel-leg coordination reduces joint torque consumption by 15.8% and 26.2% and improves stabilization through energy transfer mechanisms. Extensive evaluations on two distinct quadruped platforms achieve recovery success rates up to 99.1% and 97.8% without platform-specific tuning. The supplementary material is available at https://boyuandeng.github.io/L2R-WheelLegCoordination/

Revisiting Depth Representations for Feed-Forward 3D Gaussian Splatting

Depth maps are widely used in feed-forward 3D Gaussian Splatting (3DGS) pipelines by unprojecting them into 3D point clouds for novel view synthesis. This approach offers advantages such as efficient training, the use of known camera poses, and accurate geometry estimation. However, depth discontinuities at object boundaries often lead to fragmented or sparse point clouds, degrading rendering quality -- a well-known limitation of depth-based representations. To tackle this issue, we introduce PM-Loss, a novel regularization loss based on a pointmap predicted by a pre-trained transformer. Although the pointmap itself may be less accurate than the depth map, it effectively enforces geometric smoothness, especially around object boundaries. With the improved depth map, our method significantly improves the feed-forward 3DGS across various architectures and scenes, delivering consistently better rendering results. Our project page: https://aim-uofa.github.io/PMLoss