POCI-Diff: Position Objects Consistently and Interactively with 3D-Layout Guided Diffusion

We propose a diffusion-based approach for Text-to-Image (T2I) generation with consistent and interactive 3D layout control and editing. While prior methods improve spatial adherence using 2D cues or iterative copy-warp-paste strategies, they often distort object geometry and fail to preserve consistency across edits. To address these limitations, we introduce a framework for Positioning Objects Consistently and Interactively (POCI-Diff), a novel formulation for jointly enforcing 3D geometric constraints and instance-level semantic binding within a unified diffusion process. Our method enables explicit per-object semantic control by binding individual text descriptions to specific 3D bounding boxes through Blended Latent Diffusion, allowing one-shot synthesis of complex multi-object scenes. We further propose a warping-free generative editing pipeline that supports object insertion, removal, and transformation via regeneration rather than pixel deformation. To preserve object identity and consistency across edits, we condition the diffusion process on reference images using IP-Adapter, enabling coherent object appearance throughout interactive 3D editing while maintaining global scene coherence. Experimental results demonstrate that POCI-Diff produces high-quality images consistent with the specified 3D layouts and edits, outperforming state-of-the-art methods in both visual fidelity and layout adherence while eliminating warping-induced geometric artifacts.

Generative AI collective behavior needs an interactionist paradigm

In this article, we argue that understanding the collective behavior of agents based on large language models (LLMs) is an essential area of inquiry, with important implications in terms of risks and benefits, impacting us as a society at many levels. We claim that the distinctive nature of LLMs--namely, their initialization with extensive pre-trained knowledge and implicit social priors, together with their capability of adaptation through in-context learning--motivates the need for an interactionist paradigm consisting of alternative theoretical foundations, methodologies, and analytical tools, in order to systematically examine how prior knowledge and embedded values interact with social context to shape emergent phenomena in multi-agent generative AI systems. We propose and discuss four directions that we consider crucial for the development and deployment of LLM-based collectives, focusing on theory, methods, and trans-disciplinary dialogue.

Rethinking GNNs and Missing Features: Challenges, Evaluation and a Robust Solution

Handling missing node features is a key challenge for deploying Graph Neural Networks (GNNs) in real-world domains such as healthcare and sensor networks. Existing studies mostly address relatively benign scenarios, namely benchmark datasets with (a) high-dimensional but sparse node features and (b) incomplete data generated under Missing Completely At Random (MCAR) mechanisms. For (a), we theoretically prove that high sparsity substantially limits the information loss caused by missingness, making all models appear robust and preventing a meaningful comparison of their performance. To overcome this limitation, we introduce one synthetic and three real-world datasets with dense, semantically meaningful features. For (b), we move beyond MCAR and design evaluation protocols with more realistic missingness mechanisms. Moreover, we provide a theoretical background to state explicit assumptions on the missingness process and analyze their implications for different methods. Building on this analysis, we propose GNNmim, a simple yet effective baseline for node classification with incomplete feature data. Experiments show that GNNmim is competitive with respect to specialized architectures across diverse datasets and missingness regimes.

LLMberjack: Guided Trimming of Debate Trees for Multi-Party Conversation Creation

We present LLMberjack, a platform for creating multi-party conversations starting from existing debates, originally structured as reply trees. The system offers an interactive interface that visualizes discussion trees and enables users to construct coherent linearized dialogue sequences while preserving participant identity and discourse relations. It integrates optional large language model (LLM) assistance to support automatic editing of the messages and speakers' descriptions. We demonstrate the platform's utility by showing how tree visualization facilitates the creation of coherent, meaningful conversation threads and how LLM support enhances output quality while reducing human effort. The tool is open-source and designed to promote transparent and reproducible workflows to create multi-party conversations, addressing a lack of resources of this type.

Organ-Agents: Virtual Human Physiology Simulator via LLMs

Recent advances in large language models (LLMs) have enabled new possibilities in simulating complex physiological systems. We introduce Organ-Agents, a multi-agent framework that simulates human physiology via LLM-driven agents. Each Simulator models a specific system (e.g., cardiovascular, renal, immune). Training consists of supervised fine-tuning on system-specific time-series data, followed by reinforcement-guided coordination using dynamic reference selection and error correction. We curated data from 7,134 sepsis patients and 7,895 controls, generating high-resolution trajectories across 9 systems and 125 variables. Organ-Agents achieved high simulation accuracy on 4,509 held-out patients, with per-system MSEs <0.16 and robustness across SOFA-based severity strata. External validation on 22,689 ICU patients from two hospitals showed moderate degradation under distribution shifts with stable simulation. Organ-Agents faithfully reproduces critical multi-system events (e.g., hypotension, hyperlactatemia, hypoxemia) with coherent timing and phase progression. Evaluation by 15 critical care physicians confirmed realism and physiological plausibility (mean Likert ratings 3.9 and 3.7). Organ-Agents also enables counterfactual simulations under alternative sepsis treatment strategies, generating trajectories and APACHE II scores aligned with matched real-world patients. In downstream early warning tasks, classifiers trained on synthetic data showed minimal AUROC drops (<0.04), indicating preserved decision-relevant patterns. These results position Organ-Agents as a credible, interpretable, and generalizable digital twin for precision diagnosis, treatment simulation, and hypothesis testing in critical care.

Time Series Foundation Models are Flow Predictors

We investigate the effectiveness of time series foundation models (TSFMs) for crowd flow prediction, focusing on Moirai and TimesFM. Evaluated on three real-world mobility datasets-Bike NYC, Taxi Beijing, and Spanish national OD flows-these models are deployed in a strict zero-shot setting, using only the temporal evolution of each OD flow and no explicit spatial information. Moirai and TimesFM outperform both statistical and deep learning baselines, achieving up to 33% lower RMSE, 39% lower MAE and up to 49% higher CPC compared to state-of-the-art competitors. Our results highlight the practical value of TSFMs for accurate, scalable flow prediction, even in scenarios with limited annotated data or missing spatial context.

FreeInsert: Disentangled Text-Guided Object Insertion in 3D Gaussian Scene without Spatial Priors

Text-driven object insertion in 3D scenes is an emerging task that enables intuitive scene editing through natural language. However, existing 2D editing-based methods often rely on spatial priors such as 2D masks or 3D bounding boxes, and they struggle to ensure consistency of the inserted object. These limitations hinder flexibility and scalability in real-world applications. In this paper, we propose FreeInsert, a novel framework that leverages foundation models including MLLMs, LGMs, and diffusion models to disentangle object generation from spatial placement. This enables unsupervised and flexible object insertion in 3D scenes without spatial priors. FreeInsert starts with an MLLM-based parser that extracts structured semantics, including object types, spatial relationships, and attachment regions, from user instructions. These semantics guide both the reconstruction of the inserted object for 3D consistency and the learning of its degrees of freedom. We leverage the spatial reasoning capabilities of MLLMs to initialize object pose and scale. A hierarchical, spatially aware refinement stage further integrates spatial semantics and MLLM-inferred priors to enhance placement. Finally, the appearance of the object is improved using the inserted-object image to enhance visual fidelity. Experimental results demonstrate that FreeInsert achieves semantically coherent, spatially precise, and visually realistic 3D insertions without relying on spatial priors, offering a user-friendly and flexible editing experience.

Causal Disentanglement for Robust Long-tail Medical Image Generation

Counterfactual medical image generation effectively addresses data scarcity and enhances the interpretability of medical images. However, due to the complex and diverse pathological features of medical images and the imbalanced class distribution in medical data, generating high-quality and diverse medical images from limited data is significantly challenging. Additionally, to fully leverage the information in limited data, such as anatomical structure information and generate more structurally stable medical images while avoiding distortion or inconsistency. In this paper, in order to enhance the clinical relevance of generated data and improve the interpretability of the model, we propose a novel medical image generation framework, which generates independent pathological and structural features based on causal disentanglement and utilizes text-guided modeling of pathological features to regulate the generation of counterfactual images. First, we achieve feature separation through causal disentanglement and analyze the interactions between features. Here, we introduce group supervision to ensure the independence of pathological and identity features. Second, we leverage a diffusion model guided by pathological findings to model pathological features, enabling the generation of diverse counterfactual images. Meanwhile, we enhance accuracy by leveraging a large language model to extract lesion severity and location from medical reports. Additionally, we improve the performance of the latent diffusion model on long-tailed categories through initial noise optimization.

ESPLoRA: Enhanced Spatial Precision with Low-Rank Adaption in Text-to-Image Diffusion Models for High-Definition Synthesis

Diffusion models have revolutionized text-to-image (T2I) synthesis, producing high-quality, photorealistic images. However, they still struggle to properly render the spatial relationships described in text prompts. To address the lack of spatial information in T2I generations, existing methods typically use external network conditioning and predefined layouts, resulting in higher computational costs and reduced flexibility. Our approach builds upon a curated dataset of spatially explicit prompts, meticulously extracted and synthesized from LAION-400M to ensure precise alignment between textual descriptions and spatial layouts. Alongside this dataset, we present ESPLoRA, a flexible fine-tuning framework based on Low-Rank Adaptation, specifically designed to enhance spatial consistency in generative models without increasing generation time or compromising the quality of the outputs. In addition to ESPLoRA, we propose refined evaluation metrics grounded in geometric constraints, capturing 3D spatial relations such as \textit{in front of} or \textit{behind}. These metrics also expose spatial biases in T2I models which, even when not fully mitigated, can be strategically exploited by our TORE algorithm to further improve the spatial consistency of generated images. Our method outperforms the current state-of-the-art framework, CoMPaSS, by 13.33% on established spatial consistency benchmarks.

Boosting Relational Deep Learning with Pretrained Tabular Models

Relational databases, organized into tables connected by primary-foreign key relationships, are a common format for organizing data. Making predictions on relational data often involves transforming them into a flat tabular format through table joins and feature engineering, which serve as input to tabular methods. However, designing features that fully capture complex relational patterns remains challenging. Graph Neural Networks (GNNs) offer a compelling alternative by inherently modeling these relationships, but their time overhead during inference limits their applicability for real-time scenarios. In this work, we aim to bridge this gap by leveraging existing feature engineering efforts to enhance the efficiency of GNNs in relational databases. Specifically, we use GNNs to capture complex relationships within relational databases, patterns that are difficult to featurize, while employing engineered features to encode temporal information, thereby avoiding the need to retain the entire historical graph and enabling the use of smaller, more efficient graphs. Our \textsc{LightRDL} approach not only improves efficiency, but also outperforms existing models. Experimental results on the RelBench benchmark demonstrate that our framework achieves up to $33\%$ performance improvement and a $526\times$ inference speedup compared to GNNs, making it highly suitable for real-time inference.