SafeMed-R1: Clinician-Audited Safety and Ethics Alignment for Medical Large Language Models

Large language models(LLMs) increasingly match expert performance on licensing examinations, yet routine clinical use remains limited because governance requires auditable reasoning, safety and ethics alignment, and resilience to adversarial misuse. Here we present SafeMed-R1, trained with a traceable Clinical Trust Signals(CTS) pipeline that links each reasoning instance to clinician rubric scores and edit histories, and aligned through safety and ethics supervision and red team stress testing. SafeMed-R1 attains a macro-averaged accuracy of 79.6% across clinical benchmarks. Under adversarial safety testing, it shows the lowest aggregated risk and reduces unsafe outputs by about 3 to 5% relative to its baseline. In a paired expert study of 30 medication safety vignettes, SafeMed-R1 matches PGY1 and PGY2 residents on medical correctness and scores higher for medication safety, guideline consistency, and clinical usefulness. Collectively, these results suggest that clinician-audited supervision provenance, together with domain-tailored safety and ethics alignment, can strengthen governance-relevant evidence without relying on inference-time retrieval or citation grounding.

Dimensionality Reduction for Robust Federated Learning: A Theoretical Analysis and Convergence Guarantee

Federated Learning (FL) enables multiple clients to collaboratively train models without sharing raw data, but it is highly vulnerable to Byzantine attacks. Existing robust approaches can neutralize these threats but incur substantial computational overhead during high-dimensional gradient aggregation, an overhead that scales poorly with model size and increasingly dominates the training cost as modern models grow larger. To address this computational bottleneck, we propose Projected Dimensionality Reduction (PDR), a universal acceleration framework for vector-level distance-based robust aggregators, which performs robust aggregation by compressing gradients into a drastically smaller subspace via sparse random projection to efficiently compute reliability weights. This approach reduces the server computational complexity to an optimal $ \mathcal{O}(Mp) $, where $ M $ is the number of clients and $ p $ is the model dimension, matching the theoretical lower bound required merely to read the gradients. We establish convergence guarantees under standard FL assumptions in prior Byzantine-robust FL analyses. By leveraging the Subspace Embedding Theorem, we show that PDR achieves optimal convergence rates of $ \mathcal{O}(1/\sqrt{T}) $ for non-convex functions and $ \mathcal{O}(1/T) $ for strongly convex functions, where $ T $ denotes the number of iterations. Crucially, we mathematically demonstrate that this massive acceleration comes almost for free, merely inflating the inherent Byzantine error floor by a bounded, tunable factor of $ \frac{1+ε}{1-ε} $. Experimental results on benchmark datasets confirm that integrating PDR with existing aggregators yields orders of magnitude speedups in time efficiency while maintaining highly competitive convergence performance.

Sense Smarter, Think Better: Edge Perception for Next-Generation Networks

Edge perception has emerged as a foundational capability for future wireless networks, enabling the network edge to proactively sense, interpret, and interact with the physical environment in a task-oriented and resource-aware manner. This survey provides a comprehensive and structured overview of edge perception. We first review representative sensing modalities and edge artificial intelligence (AI) techniques as the fundamental building blocks. We then examine their synergistic interactions. We systematically analyze how edge AI enhances sensing capabilities, encompassing both in-band and out-of-band modalities, as well as multi-modal sensor data fusion. Moreover, we discuss the role of task-driven sensing in facilitating edge AI, including integrated sensing-communication-computation designs, and active perception frameworks that dynamically adapt sensing strategies for downstream applications. Finally, we identify key challenges and open issues. By consolidating fragmented research across sensing, communication, and edge AI, this survey provides forward-looking insights for the design and implementation of edge perception systems for sixth-generation (6G) networks.

DisAgg: Distributed Aggregators for Efficient Secure Aggregation in Federated Learning

Federated learning enables collaborative model training across distributed clients, yet vanilla FL exposes client updates to the central server. Secure-aggregation schemes protect privacy against an honest-but-curious server, but existing approaches often suffer from many communication rounds, heavy public-key operations, or difficulty handling client dropouts. Recent methods like One-Shot Private Aggregation (OPA) cut rounds to a single server interaction per FL iteration, yet they impose substantial cryptographic and computational overhead on both server and clients. We propose a new protocol called DisAgg that leverages a small committee of clients called Aggregators to perform the aggregation itself: each client secret-shares its update vector to Aggregators, which locally compute partial sums and return only aggregated shares for server-side reconstruction. This design eliminates local masking and expensive homomorphic encryption, reducing endpoint computation while preserving privacy against a curious server and a limited fraction of colluding clients. By leveraging optimal trade-offs between communication and computation costs, DisAgg processes 100k-dimensional update vectors from 100k 5G clients with a 4.6x speedup compared to OPA, the previous best protocol.

DP-LAC: Lightweight Adaptive Clipping for Differentially Private Federated Fine-tuning of Language Models

Federated learning (FL) enables the collaborative training of large-scale language models (LLMs) across edge devices while keeping user data on-device. However, FL still exposes sensitive information through client-provided gradients. Differentially private stochastic gradient descent (DP-SGD) mitigates this risk by clipping each client's contribution to a threshold $C$ and adding noise proportional to $C$. Existing adaptive clipping techniques dynamically adjust $C$ but demand tedious hyperparameter tuning, which can erode the privacy budget. In this paper, we introduce DP-LAC, a method that first estimates an initial clipping threshold within an order of magnitude of the optimum using private histogram estimation, and then adapts this threshold during training without consuming additional privacy budget or introducing new hyperparameters. Empirical results show that DP-LAC outperforms both state-of-the-art adaptive clipping methods and vanilla DP-SGD, achieving an average accuracy gain of $6.6\%$.

OphMAE: Bridging Volumetric and Planar Imaging with a Foundation Model for Adaptive Ophthalmological Diagnosis

The advent of foundation models has heralded a new era in medical artificial intelligence (AI), enabling the extraction of generalizable representations from large-scale unlabeled datasets. However, current ophthalmic AI paradigms are predominantly constrained to single-modality inference, thereby creating a dissonance with clinical practice where diagnosis relies on the synthesis of complementary imaging modalities. Furthermore, the deployment of high-performance AI in resource-limited settings is frequently impeded by the unavailability of advanced three-dimensional imaging hardware. Here, we present the Ophthalmic multimodal Masked Autoencoder (OphMAE), a multi-imaging foundation model engineered to synergize the volumetric depth of 3D Optical Coherence Tomography (OCT) with the planar context of 2D en face OCT. By implementing a novel cross-modal fusion architecture and a unique adaptive inference mechanism, OphMAE was pre-trained on a massive dataset with of 183,875 paired OCT images derived from 32,765 patients. In a rigorous benchmark encompassing 17 diverse diagnostic tasks with 48,340 paired OCT images from 8,191 patients, the model demonstrated state-of-the-art performance, achieving an Area Under the Curve (AUC) of 96.9% for Age-related Macular Degeneration (AMD) and 97.2% for Diabetic Macular Edema (DME), consistently surpassing existing single-modal and multimodal foundation models. Crucially, OphMAE exhibits robust engineering adaptability: it maintains high diagnostic accuracy, such as 93.7\% AUC for AMD, even when restricted to single-modality 2D inputs, and demonstrates exceptional data efficiency by retaining 95.7% AUC with as few as 500 labeled samples. This work establishes a scalable and adaptable framework for ophthalmic AI, ensuring robust performance across different tasks.

Differentially Private Clustered Federated Learning with Privacy-Preserving Initialization and Normality-Driven Aggregation

Federated learning (FL) enables training of a global model while keeping raw data on end-devices. Despite this, FL has shown to leak private user information and thus in practice, it is often coupled with methods such as differential privacy (DP) and secure vector sum to provide formal privacy guarantees to its participants. In realistic cross-device deployments, the data are highly heterogeneous, so vanilla federated learning converges slowly and generalizes poorly. Clustered federated learning (CFL) mitigates this by segregating users into clusters, leading to lower intra-cluster data heterogeneity. Nevertheless, coupling CFL with DP remains challenging: the injected DP noise makes individual client updates excessively noisy, and the server is unable to initialize cluster centroids with the less noisy aggregated updates. To address this challenge, we propose PINA, a two-stage framework that first lets each client fine-tune a lightweight low-rank adaptation (LoRA) adapter and privately share a compressed sketch of the update. The server leverages these sketches to construct robust cluster centroids. In the second stage, PINA introduces a normality-driven aggregation mechanism that improves convergence and robustness. Our method retains the benefits of clustered FL while providing formal privacy guarantees against an untrusted server. Extensive evaluations show that our proposed method outperforms state-of-the-art DP-FL algorithms by an average of 2.9% in accuracy for privacy budgets (epsilon in {2, 8}).

Culture-Aware Humorous Captioning: Multimodal Humor Generation across Cultural Contexts

Recent multimodal large language models have shown promising ability in generating humorous captions for images, yet they still lack stable control over explicit cultural context, making it difficult to jointly maintain image relevance, contextual appropriateness, and humor quality under a specified cultural background. To address this limitation, we introduce a new multimodal generation task, culture-aware humorous captioning, which requires a model to generate a humorous caption conditioned on both an input image and a target cultural context. Captions generated under different cultural contexts are not expected to share the same surface form, but should remain grounded in similar visual situations or humorous rationales.To support this task, we establish a six-dimensional evaluation framework covering image relevance, contextual fit, semantic richness, reasonableness, humor, and creativity. We further propose a staged alignment framework that first initializes the model with high-resource supervision under the Western cultural context, then performs multi-dimensional preference alignment via judge-based GRPO with a Degradation-aware Prototype Repulsion Constraint to mitigate reward hacking in open-ended generation, and finally adapts the model to the Eastern cultural context with a small amount of supervision. Experimental results show that our method achieves stronger overall performance under the proposed evaluation framework, with particularly large gains in contextual fit and a better balance between image relevance and humor under cultural constraints.

VBGS-SLAM: Variational Bayesian Gaussian Splatting Simultaneous Localization and Mapping

3D Gaussian Splatting (3DGS) has shown promising results for 3D scene modeling using mixtures of Gaussians, yet its existing simultaneous localization and mapping (SLAM) variants typically rely on direct, deterministic pose optimization against the splat map, making them sensitive to initialization and susceptible to catastrophic forgetting as map evolves. We propose Variational Bayesian Gaussian Splatting SLAM (VBGS-SLAM), a novel framework that couples the splat map refinement and camera pose tracking in a generative probabilistic form. By leveraging conjugate properties of multivariate Gaussians and variational inference, our method admits efficient closed-form updates and explicitly maintains posterior uncertainty over both poses and scene parameters. This uncertainty-aware method mitigates drift and enhances robustness in challenging conditions, while preserving the efficiency and rendering quality of existing 3DGS. Our experiments demonstrate superior tracking performance and robustness in long sequence prediction, alongside efficient, high-quality novel view synthesis across diverse synthetic and real-world scenes.

The Latent Space: Foundation, Evolution, Mechanism, Ability, and Outlook

Latent space is rapidly emerging as a native substrate for language-based models. While modern systems are still commonly understood through explicit token-level generation, an increasing body of work shows that many critical internal processes are more naturally carried out in continuous latent space than in human-readable verbal traces. This shift is driven by the structural limitations of explicit-space computation, including linguistic redundancy, discretization bottlenecks, sequential inefficiency, and semantic loss. This survey aims to provide a unified and up-to-date landscape of latent space in language-based models. We organize the survey into five sequential perspectives: Foundation, Evolution, Mechanism, Ability, and Outlook. We begin by delineating the scope of latent space, distinguishing it from explicit or verbal space and from the latent spaces commonly studied in generative visual models. We then trace the field's evolution from early exploratory efforts to the current large-scale expansion. To organize the technical landscape, we examine existing work through the complementary lenses of mechanism and ability. From the perspective of Mechanism, we identify four major lines of development: Architecture, Representation, Computation, and Optimization. From the perspective of Ability, we show how latent space supports a broad capability spectrum spanning Reasoning, Planning, Modeling, Perception, Memory, Collaboration, and Embodiment. Beyond consolidation, we discuss the key open challenges, and outline promising directions for future research. We hope this survey serves not only as a reference for existing work, but also as a foundation for understanding latent space as a general computational and systems paradigm for next-generation intelligence.