Meta Additive Model: Interpretable Sparse Learning With Auto Weighting

Sparse additive models have attracted much attention in high-dimensional data analysis due to their flexible representation and strong interpretability. However, most existing models are limited to single-level learning under the mean-squared error criterion, whose empirical performance can degrade significantly in the presence of complex noise, such as non-Gaussian perturbations, outliers, noisy labels, and imbalanced categories. The sample reweighting strategy is widely used to reduce the model's sensitivity to atypical data; however, it typically requires prespecifying the weighting functions and manually selecting additional hyperparameters. To address this issue, we propose a new meta additive model (MAM) based on the bilevel optimization framework, which learns data-driven weighting of individual losses by parameterizing the weighting function via an MLP trained on meta data. MAM is capable of a variety of learning tasks, including variable selection, robust regression estimation, and imbalanced classification. Theoretically, MAM provides guarantees on convergence in computation, algorithmic generalization, and variable selection consistency under mild conditions. Empirically, MAM outperforms several state-of-the-art additive models on both synthetic and real-world data under various data corruptions.

S2MAM: Semi-supervised Meta Additive Model for Robust Estimation and Variable Selection

Semi-supervised learning with manifold regularization is a classical framework for jointly learning from both labeled and unlabeled data, where the key requirement is that the support of the unknown marginal distribution has the geometric structure of a Riemannian manifold. Typically, the Laplace-Beltrami operator-based manifold regularization can be approximated empirically by the Laplacian regularization associated with the entire training data and its corresponding graph Laplacian matrix. However, the graph Laplacian matrix depends heavily on the prespecified similarity metric and may lead to inappropriate penalties when dealing with redundant or noisy input variables. To address the above issues, this paper proposes a new \textit{Semi-Supervised Meta Additive Model (S$^2$MAM) based on a bilevel optimization scheme that automatically identifies informative variables, updates the similarity matrix, and simultaneously achieves interpretable predictions. Theoretical guarantees are provided for S$^2$MAM, including the computing convergence and the statistical generalization bound. Experimental assessments across 4 synthetic and 12 real-world datasets, with varying levels and categories of corruption, validate the robustness and interpretability of the proposed approach.

MedProbeBench: Systematic Benchmarking at Deep Evidence Integration for Expert-level Medical Guideline

Recent advances in deep research systems enable large language models to retrieve, synthesize, and reason over large-scale external knowledge. In medicine, developing clinical guidelines critically depends on such deep evidence integration. However, existing benchmarks fail to evaluate this capability in realistic workflows requiring multi-step evidence integration and expert-level judgment. To address this gap, we introduce MedProbeBench, the first benchmark leveraging high-quality clinical guidelines as expert-level references. Medical guidelines, with their rigorous standards in neutrality and verifiability, represent the pinnacle of medical expertise and pose substantial challenges for deep research agents. For evaluation, we propose MedProbe-Eval, a comprehensive evaluation framework featuring: (1) Holistic Rubrics with 1,200+ task-adaptive rubric criteria for comprehensive quality assessment, and (2) Fine-grained Evidence Verification for rigorous validation of evidence precision, grounded in 5,130+ atomic claims. Evaluation of 17 LLMs and deep research agents reveals critical gaps in evidence integration and guideline generation, underscoring the substantial distance between current capabilities and expert-level clinical guideline development. Project: https://github.com/uni-medical/MedProbeBench

Open-Ended Instruction Realization with LLM-Enabled Multi-Planner Scheduling in Autonomous Vehicles

Most Human-Machine Interaction (HMI) research overlooks the maneuvering needs of passengers in autonomous driving (AD). Natural language offers an intuitive interface, yet translating passenger open-ended instructions into control signals, without sacrificing interpretability and traceability, remains a challenge. This study proposes an instruction-realization framework that leverages a large language model (LLM) to interpret instructions, generates executable scripts that schedule multiple model predictive control (MPC)-based motion planners based on real-time feedback, and converts planned trajectories into control signals. This scheduling-centric design decouples semantic reasoning from vehicle control at different timescales, establishing a transparent, traceable decision-making chain from high-level instructions to low-level actions. Due to the absence of high-fidelity evaluation tools, this study introduces a benchmark for open-ended instruction realization in a closed-loop setting. Comprehensive experiments reveal that the framework significantly improves task-completion rates over instruction-realization baselines, reduces LLM query costs, achieves safety and compliance on par with specialized AD approaches, and exhibits considerable tolerance to LLM inference latency. For more qualitative illustrations and a clearer understanding.

Human-AI Co-reasoning for Clinical Diagnosis with Evidence-Integrated Language Agent

We present PULSE, a medical reasoning agent that combines a domain-tuned large language model with scientific literature retrieval to support diagnostic decision-making in complex real-world cases. To evaluate its capabilities, we curated a benchmark of 82 authentic endocrinology case reports encompassing a broad spectrum of disease types and incidence levels. In controlled experiments, we compared PULSE's performance against physicians with varying levels of expertise-from residents to senior specialists-and examined how AI assistance influenced human diagnostic reasoning. PULSE attained expert-competitive accuracy, outperforming residents and junior specialists while matching senior specialist performance at both Top@1 and Top@4 thresholds. Unlike physicians, whose accuracy declined with disease rarity, PULSE maintained stable performance across incidence tiers. The agent also exhibited adaptive reasoning, increasing output length with case difficulty in a manner analogous to the longer deliberation observed among expert clinicians. When used collaboratively, PULSE enabled physicians to correct initial errors and broaden diagnostic hypotheses, but also introduced risks of automation bias. The study explores both serial and concurrent collaboration workflows, revealing that PULSE offers robust support across common and rare presentations. These findings underscore both the promise and the limitations of language model-based agents in clinical diagnosis, and offer a framework for evaluating their role in real-world decision-making.

Beyond False Discovery Rate: A Stepdown Group SLOPE Approach for Grouped Variable Selection

High-dimensional feature selection is routinely required to balance statistical power with strict control of multiple-error metrics such as the k-Family-Wise Error Rate (k-FWER) and the False Discovery Proportion (FDP), yet some existing frameworks are confined to the narrower goal of controlling the expected False Discovery Rate (FDR) and can not exploit the group-structure of the covariates, such as Sorted L-One Penalized Estimation (SLOPE). We introduce the Group Stepdown SLOPE, a unified optimization procedure which is capable of embedding the Lehmann-Romano stepdown rules into SLOPE to achieve finite-sample guarantees under k-FWER and FDP thresholds. Specifically, we derive closed-form regularization sequences under orthogonal designs that provably bound k-FWER and FDP at user-specified levels, and extend these results to grouped settings via gk-SLOPE and gF-SLOPE, which control the analogous group-level errors gk-FWER and gFDP. For non-orthogonal general designs, we provide a calibrated data-driven sequence inspired by Gaussian approximation and Monte-Carlo correction, preserving convexity and scalability. Extensive simulations are conducted across sparse, correlated, and group-structured regimes. Empirical results corroborate our theoretical findings that the proposed methods achieve nominal error control, while yielding markedly higher power than competing stepdown procedures, thereby confirming the practical value of the theoretical advances.

MemEmo: Evaluating Emotion in Memory Systems of Agents

Memory systems address the challenge of context loss in Large Language Model during prolonged interactions. However, compared to human cognition, the efficacy of these systems in processing emotion-related information remains inconclusive. To address this gap, we propose an emotion-enhanced memory evaluation benchmark to assess the performance of mainstream and state-of-the-art memory systems in handling affective information. We developed the \textbf{H}uman-\textbf{L}ike \textbf{M}emory \textbf{E}motion (\textbf{HLME}) dataset, which evaluates memory systems across three dimensions: emotional information extraction, emotional memory updating, and emotional memory question answering. Experimental results indicate that none of the evaluated systems achieve robust performance across all three tasks. Our findings provide an objective perspective on the current deficiencies of memory systems in processing emotional memories and suggest a new trajectory for future research and system optimization.

Mitigating Membership Inference in Intermediate Representations via Layer-wise MIA-risk-aware DP-SGD

In Embedding-as-an-Interface (EaaI) settings, pre-trained models are queried for Intermediate Representations (IRs). The distributional properties of IRs can leak training-set membership signals, enabling Membership Inference Attacks (MIAs) whose strength varies across layers. Although Differentially Private Stochastic Gradient Descent (DP-SGD) mitigates such leakage, existing implementations employ per-example gradient clipping and a uniform, layer-agnostic noise multiplier, ignoring heterogeneous layer-wise MIA vulnerability. This paper introduces Layer-wise MIA-risk-aware DP-SGD (LM-DP-SGD), which adaptively allocates privacy protection across layers in proportion to their MIA risk. Specifically, LM-DP-SGD trains a shadow model on a public shadow dataset, extracts per-layer IRs from its train/test splits, and fits layer-specific MIA adversaries, using their attack error rates as MIA-risk estimates. Leveraging the cross-dataset transferability of MIAs, these estimates are then used to reweight each layer's contribution to the globally clipped gradient during private training, providing layer-appropriate protection under a fixed noise magnitude. We further establish theoretical guarantees on both privacy and convergence of LM-DP-SGD. Extensive experiments show that, under the same privacy budget, LM-DP-SGD reduces the peak IR-level MIA risk while preserving utility, yielding a superior privacy-utility trade-off.

DP-aware AdaLN-Zero: Taming Conditioning-Induced Heavy-Tailed Gradients in Differentially Private Diffusion

Condition injection enables diffusion models to generate context-aware outputs, which is essential for many time-series tasks. However, heterogeneous conditional contexts (e.g., observed history, missingness patterns or outlier covariates) can induce heavy-tailed per-example gradients. Under Differentially Private Stochastic Gradient Descent (DP-SGD), these rare conditioning-driven heavy-tailed gradients disproportionately trigger global clipping, resulting in outlier-dominated updates, larger clipping bias, and degraded utility under a fixed privacy budget. In this paper, we propose DP-aware AdaLN-Zero, a drop-in sensitivity-aware conditioning mechanism for conditional diffusion transformers that limits conditioning-induced gain without modifying the DP-SGD mechanism. DP-aware AdaLN-Zero jointly constrains conditioning representation magnitude and AdaLN modulation parameters via bounded re-parameterization, suppressing extreme gradient tail events before gradient clipping and noise injection. Empirically, DP-SGD equipped with DP-aware AdaLN-Zero improves interpolation/imputation and forecasting under matched privacy settings. We observe consistent gains on a real-world power dataset and two public ETT benchmarks over vanilla DP-SGD. Moreover, gradient diagnostics attribute these improvements to conditioning-specific tail reshaping and reduced clipping distortion, while preserving expressiveness in non-private training. Overall, these results show that sensitivity-aware conditioning can substantially improve private conditional diffusion training without sacrificing standard performance.

Who Deserves the Reward? SHARP: Shapley Credit-based Optimization for Multi-Agent System

Integrating Large Language Models (LLMs) with external tools via multi-agent systems offers a promising new paradigm for decomposing and solving complex problems. However, training these systems remains notoriously difficult due to the credit assignment challenge, as it is often unclear which specific functional agent is responsible for the success or failure of decision trajectories. Existing methods typically rely on sparse or globally broadcast rewards, failing to capture individual contributions and leading to inefficient reinforcement learning. To address these limitations, we introduce the Shapley-based Hierarchical Attribution for Reinforcement Policy (SHARP), a novel framework for optimizing multi-agent reinforcement learning via precise credit attribution. SHARP effectively stabilizes training by normalizing agent-specific advantages across trajectory groups, primarily through a decomposed reward mechanism comprising a global broadcast-accuracy reward, a Shapley-based marginal-credit reward for each agent, and a tool-process reward to improve execution efficiency. Extensive experiments across various real-world benchmarks demonstrate that SHARP significantly outperforms recent state-of-the-art baselines, achieving average match improvements of 23.66% and 14.05% over single-agent and multi-agent approaches, respectively.