MedRAX: Medical Reasoning Agent for Chest X-ray

Chest X-rays (CXRs) play an integral role in driving critical decisions in disease management and patient care. While recent innovations have led to specialized models for various CXR interpretation tasks, these solutions often operate in isolation, limiting their practical utility in clinical practice. We present MedRAX, the first versatile AI agent that seamlessly integrates state-of-the-art CXR analysis tools and multimodal large language models into a unified framework. MedRAX dynamically leverages these models to address complex medical queries without requiring additional training. To rigorously evaluate its capabilities, we introduce ChestAgentBench, a comprehensive benchmark containing 2,500 complex medical queries across 7 diverse categories. Our experiments demonstrate that MedRAX achieves state-of-the-art performance compared to both open-source and proprietary models, representing a significant step toward the practical deployment of automated CXR interpretation systems. Data and code have been publicly available at https://github.com/bowang-lab/MedRAX

Explicit vs. Implicit: Investigating Social Bias in Large Language Models through Self-Reflection

Large Language Models (LLMs) have been shown to exhibit various biases and stereotypes in their generated content. While extensive research has investigated bias in LLMs, prior work has predominantly focused on explicit bias, leaving the more nuanced implicit biases largely unexplored. This paper presents a systematic framework grounded in social psychology theories to investigate and compare explicit and implicit biases in LLMs. We propose a novel "self-reflection" based evaluation framework that operates in two phases: first measuring implicit bias through simulated psychological assessment methods, then evaluating explicit bias by prompting LLMs to analyze their own generated content. Through extensive experiments on state-of-the-art LLMs across multiple social dimensions, we demonstrate that LLMs exhibit a substantial inconsistency between explicit and implicit biases, where explicit biases manifest as mild stereotypes while implicit biases show strong stereotypes. Furthermore, we investigate the underlying factors contributing to this explicit-implicit bias inconsistency. Our experiments examine the effects of training data scale, model parameters, and alignment techniques. Results indicate that while explicit bias diminishes with increased training data and model size, implicit bias exhibits a contrasting upward trend. Notably, contemporary alignment methods (e.g., RLHF, DPO) effectively suppress explicit bias but show limited efficacy in mitigating implicit bias. These findings suggest that while scaling up models and alignment training can address explicit bias, the challenge of implicit bias requires novel approaches beyond current methodologies.

Hear the Scene: Audio-Enhanced Text Spotting

Recent advancements in scene text spotting have focused on end-to-end methodologies that heavily rely on precise location annotations, which are often costly and labor-intensive to procure. In this study, we introduce an innovative approach that leverages only transcription annotations for training text spotting models, substantially reducing the dependency on elaborate annotation processes. Our methodology employs a query-based paradigm that facilitates the learning of implicit location features through the interaction between text queries and image embeddings. These features are later refined during the text recognition phase using an attention activation map. Addressing the challenges associated with training a weakly-supervised model from scratch, we implement a circular curriculum learning strategy to enhance model convergence. Additionally, we introduce a coarse-to-fine cross-attention localization mechanism for more accurate text instance localization. Notably, our framework supports audio-based annotation, which significantly diminishes annotation time and provides an inclusive alternative for individuals with disabilities. Our approach achieves competitive performance against existing benchmarks, demonstrating that high accuracy in text spotting can be attained without extensive location annotations.

Mamba-based Deep Learning Approaches for Sleep Staging on a Wireless Multimodal Wearable System without Electroencephalography

Study Objectives: We investigate using Mamba-based deep learning approaches for sleep staging on signals from ANNE One (Sibel Health, Evanston, IL), a minimally intrusive dual-sensor wireless wearable system measuring chest electrocardiography (ECG), triaxial accelerometry, and temperature, as well as finger photoplethysmography (PPG) and temperature. Methods: We obtained wearable sensor recordings from 360 adults undergoing concurrent clinical polysomnography (PSG) at a tertiary care sleep lab. PSG recordings were scored according to AASM criteria. PSG and wearable sensor data were automatically aligned using their ECG channels with manual confirmation by visual inspection. We trained Mamba-based models with both convolutional-recurrent neural network (CRNN) and the recurrent neural network (RNN) architectures on these recordings. Ensembling of model variants with similar architectures was performed. Results: Our best approach, after ensembling, attains a 3-class (wake, NREM, REM) balanced accuracy of 83.50%, F1 score of 84.16%, Cohen's $\kappa$ of 72.68%, and a MCC score of 72.84%; a 4-class (wake, N1/N2, N3, REM) balanced accuracy of 74.64%, F1 score of 74.56%, Cohen's $\kappa$ of 61.63%, and MCC score of 62.04%; a 5-class (wake, N1, N2, N3, REM) balanced accuracy of 64.30%, F1 score of 66.97%, Cohen's $\kappa$ of 53.23%, MCC score of 54.38%. Conclusions: Deep learning models can infer major sleep stages from a wearable system without electroencephalography (EEG) and can be successfully applied to data from adults attending a tertiary care sleep clinic.

Efficient MedSAMs: Segment Anything in Medical Images on Laptop

Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical practice. In this work, we organized the first international competition dedicated to promptable medical image segmentation, featuring a large-scale dataset spanning nine common imaging modalities from over 20 different institutions. The top teams developed lightweight segmentation foundation models and implemented an efficient inference pipeline that substantially reduced computational requirements while maintaining state-of-the-art segmentation accuracy. Moreover, the post-challenge phase advanced the algorithms through the design of performance booster and reproducibility tasks, resulting in improved algorithms and validated reproducibility of the winning solution. Furthermore, the best-performing algorithms have been incorporated into the open-source software with a user-friendly interface to facilitate clinical adoption. The data and code are publicly available to foster the further development of medical image segmentation foundation models and pave the way for impactful real-world applications.

EvoWiki: Evaluating LLMs on Evolving Knowledge

Knowledge utilization is a critical aspect of LLMs, and understanding how they adapt to evolving knowledge is essential for their effective deployment. However, existing benchmarks are predominantly static, failing to capture the evolving nature of LLMs and knowledge, leading to inaccuracies and vulnerabilities such as contamination. In this paper, we introduce EvoWiki, an evolving dataset designed to reflect knowledge evolution by categorizing information into stable, evolved, and uncharted states. EvoWiki is fully auto-updatable, enabling precise evaluation of continuously changing knowledge and newly released LLMs. Through experiments with Retrieval-Augmented Generation (RAG) and Contunual Learning (CL), we evaluate how effectively LLMs adapt to evolving knowledge. Our results indicate that current models often struggle with evolved knowledge, frequently providing outdated or incorrect responses. Moreover, the dataset highlights a synergistic effect between RAG and CL, demonstrating their potential to better adapt to evolving knowledge. EvoWiki provides a robust benchmark for advancing future research on the knowledge evolution capabilities of large language models.

Scaling of Search and Learning: A Roadmap to Reproduce o1 from Reinforcement Learning Perspective

OpenAI o1 represents a significant milestone in Artificial Inteiligence, which achieves expert-level performances on many challanging tasks that require strong reasoning ability.OpenAI has claimed that the main techinique behinds o1 is the reinforcement learining. Recent works use alternative approaches like knowledge distillation to imitate o1's reasoning style, but their effectiveness is limited by the capability ceiling of the teacher model. Therefore, this paper analyzes the roadmap to achieving o1 from the perspective of reinforcement learning, focusing on four key components: policy initialization, reward design, search, and learning. Policy initialization enables models to develop human-like reasoning behaviors, equipping them with the ability to effectively explore solution spaces for complex problems. Reward design provides dense and effective signals via reward shaping or reward modeling, which is the guidance for both search and learning. Search plays a crucial role in generating high-quality solutions during both training and testing phases, which can produce better solutions with more computation. Learning utilizes the data generated by search for improving policy, which can achieve the better performance with more parameters and more searched data. Existing open-source projects that attempt to reproduce o1 can be seem as a part or a variant of our roadmap. Collectively, these components underscore how learning and search drive o1's advancement, making meaningful contributions to the development of LLM.

AIR-Bench: Automated Heterogeneous Information Retrieval Benchmark

Evaluation plays a crucial role in the advancement of information retrieval (IR) models. However, current benchmarks, which are based on predefined domains and human-labeled data, face limitations in addressing evaluation needs for emerging domains both cost-effectively and efficiently. To address this challenge, we propose the Automated Heterogeneous Information Retrieval Benchmark (AIR-Bench). AIR-Bench is distinguished by three key features: 1) Automated. The testing data in AIR-Bench is automatically generated by large language models (LLMs) without human intervention. 2) Heterogeneous. The testing data in AIR-Bench is generated with respect to diverse tasks, domains and languages. 3) Dynamic. The domains and languages covered by AIR-Bench are constantly augmented to provide an increasingly comprehensive evaluation benchmark for community developers. We develop a reliable and robust data generation pipeline to automatically create diverse and high-quality evaluation datasets based on real-world corpora. Our findings demonstrate that the generated testing data in AIR-Bench aligns well with human-labeled testing data, making AIR-Bench a dependable benchmark for evaluating IR models. The resources in AIR-Bench are publicly available at https://github.com/AIR-Bench/AIR-Bench.

Text-Video Multi-Grained Integration for Video Moment Montage

The proliferation of online short video platforms has driven a surge in user demand for short video editing. However, manually selecting, cropping, and assembling raw footage into a coherent, high-quality video remains laborious and time-consuming. To accelerate this process, we focus on a user-friendly new task called Video Moment Montage (VMM), which aims to accurately locate the corresponding video segments based on a pre-provided narration text and then arrange these video clips to create a complete video that aligns with the corresponding descriptions. The challenge lies in extracting precise temporal segments while ensuring intra-sentence and inter-sentence context consistency, as a single script sentence may require trimming and assembling multiple video clips. To address this problem, we present a novel \textit{Text-Video Multi-Grained Integration} method (TV-MGI) that efficiently fuses text features from the script with both shot-level and frame-level video features, which enables the global and fine-grained alignment between the video content and the corresponding textual descriptions in the script. To facilitate further research in this area, we introduce the Multiple Sentences with Shots Dataset (MSSD), a large-scale dataset designed explicitly for the VMM task. We conduct extensive experiments on the MSSD dataset to demonstrate the effectiveness of our framework compared to baseline methods.

Semantic Scene Completion Based 3D Traversability Estimation for Off-Road Terrains

Off-road environments present significant challenges for autonomous ground vehicles due to the absence of structured roads and the presence of complex obstacles, such as uneven terrain, vegetation, and occlusions. Traditional perception algorithms, designed primarily for structured environments, often fail under these conditions, leading to inaccurate traversability estimations. In this paper, ORDformer, a novel multimodal method that combines LiDAR point clouds with monocular images, is proposed to generate dense traversable occupancy predictions from a forward-facing perspective. By integrating multimodal data, environmental feature extraction is enhanced, which is crucial for accurate occupancy estimation in complex terrains. Furthermore, RELLIS-OCC, a dataset with 3D traversable occupancy annotations, is introduced, incorporating geometric features such as step height, slope, and unevenness. Through a comprehensive analysis of vehicle obstacle-crossing conditions and the incorporation of vehicle body structure constraints, four traversability cost labels are generated: lethal, medium-cost, low-cost, and free. Experimental results demonstrate that ORDformer outperforms existing approaches in 3D traversable area recognition, particularly in off-road environments with irregular geometries and partial occlusions. Specifically, ORDformer achieves over a 20\% improvement in scene completion IoU compared to other models. The proposed framework is scalable and adaptable to various vehicle platforms, allowing for adjustments to occupancy grid parameters and the integration of advanced dynamic models for traversability cost estimation.