Abstract:Web-crawled image-text pairs are inherently noisy. Prior studies demonstrate that semantically aligning and enriching textual descriptions of these pairs can significantly enhance model training across various vision-language tasks, particularly text-to-image generation. However, large-scale investigations in this area remain predominantly closed-source. Our paper aims to bridge this community effort, leveraging the powerful and \textit{open-sourced} LLaMA-3, a GPT-4 level LLM. Our recaptioning pipeline is simple: first, we fine-tune a LLaMA-3-8B powered LLaVA-1.5 and then employ it to recaption 1.3 billion images from the DataComp-1B dataset. Our empirical results confirm that this enhanced dataset, Recap-DataComp-1B, offers substantial benefits in training advanced vision-language models. For discriminative models like CLIP, we observe enhanced zero-shot performance in cross-modal retrieval tasks. For generative models like text-to-image Diffusion Transformers, the generated images exhibit a significant improvement in alignment with users' text instructions, especially in following complex queries. Our project page is https://www.haqtu.me/Recap-Datacomp-1B/
Abstract:Image deep features extracted by pre-trained networks are known to contain rich and informative representations. In this paper, we present Deep Degradation Response (DDR), a method to quantify changes in image deep features under varying degradation conditions. Specifically, our approach facilitates flexible and adaptive degradation, enabling the controlled synthesis of image degradation through text-driven prompts. Extensive evaluations demonstrate the versatility of DDR as an image descriptor, with strong correlations observed with key image attributes such as complexity, colorfulness, sharpness, and overall quality. Moreover, we demonstrate the efficacy of DDR across a spectrum of applications. It excels as a blind image quality assessment metric, outperforming existing methodologies across multiple datasets. Additionally, DDR serves as an effective unsupervised learning objective in image restoration tasks, yielding notable advancements in image deblurring and single-image super-resolution. Our code will be made available.
Abstract:This study presents Medical Vision Generalist (MVG), the first foundation model capable of handling various medical imaging tasks -- such as cross-modal synthesis, image segmentation, denoising, and inpainting -- within a unified image-to-image generation framework. Specifically, MVG employs an in-context generation strategy that standardizes the handling of inputs and outputs as images. By treating these tasks as an image generation process conditioned on prompt image-label pairs and input images, this approach enables a flexible unification of various tasks, even those spanning different modalities and datasets. To capitalize on both local and global context, we design a hybrid method combining masked image modeling with autoregressive training for conditional image generation. This hybrid approach yields the most robust performance across all involved medical imaging tasks. To rigorously evaluate MVG's capabilities, we curated the first comprehensive generalist medical vision benchmark, comprising 13 datasets and spanning four imaging modalities (CT, MRI, X-ray, and micro-ultrasound). Our results consistently establish MVG's superior performance, outperforming existing vision generalists, such as Painter and LVM. Furthermore, MVG exhibits strong scalability, with its performance demonstrably improving when trained on a more diverse set of tasks, and can be effectively adapted to unseen datasets with only minimal task-specific samples. The code is available at \url{https://github.com/OliverRensu/MVG}.
Abstract:CRATE, a white-box transformer architecture designed to learn compressed and sparse representations, offers an intriguing alternative to standard vision transformers (ViTs) due to its inherent mathematical interpretability. Despite extensive investigations into the scaling behaviors of language and vision transformers, the scalability of CRATE remains an open question which this paper aims to address. Specifically, we propose CRATE-$\alpha$, featuring strategic yet minimal modifications to the sparse coding block in the CRATE architecture design, and a light training recipe designed to improve the scalability of CRATE. Through extensive experiments, we demonstrate that CRATE-$\alpha$ can effectively scale with larger model sizes and datasets. For example, our CRATE-$\alpha$-B substantially outperforms the prior best CRATE-B model accuracy on ImageNet classification by 3.7%, achieving an accuracy of 83.2%. Meanwhile, when scaling further, our CRATE-$\alpha$-L obtains an ImageNet classification accuracy of 85.1%. More notably, these model performance improvements are achieved while preserving, and potentially even enhancing the interpretability of learned CRATE models, as we demonstrate through showing that the learned token representations of increasingly larger trained CRATE-$\alpha$ models yield increasingly higher-quality unsupervised object segmentation of images. The project page is https://rayjryang.github.io/CRATE-alpha/.
Abstract:Denoising diffusion probabilistic models (DDPMs) have achieved unprecedented success in computer vision. However, they remain underutilized in medical imaging, a field crucial for disease diagnosis and treatment planning. This is primarily due to the high computational cost associated with (1) the use of large number of time steps (e.g., 1,000) in diffusion processes and (2) the increased dimensionality of medical images, which are often 3D or 4D. Training a diffusion model on medical images typically takes days to weeks, while sampling each image volume takes minutes to hours. To address this challenge, we introduce Fast-DDPM, a simple yet effective approach capable of improving training speed, sampling speed, and generation quality simultaneously. Unlike DDPM, which trains the image denoiser across 1,000 time steps, Fast-DDPM trains and samples using only 10 time steps. The key to our method lies in aligning the training and sampling procedures to optimize time-step utilization. Specifically, we introduced two efficient noise schedulers with 10 time steps: one with uniform time step sampling and another with non-uniform sampling. We evaluated Fast-DDPM across three medical image-to-image generation tasks: multi-image super-resolution, image denoising, and image-to-image translation. Fast-DDPM outperformed DDPM and current state-of-the-art methods based on convolutional networks and generative adversarial networks in all tasks. Additionally, Fast-DDPM reduced the training time to 0.2x and the sampling time to 0.01x compared to DDPM. Our code is publicly available at: https://github.com/mirthAI/Fast-DDPM.
Abstract:Denoising diffusion probabilistic models (DDPMs) have achieved unprecedented success in computer vision. However, they remain underutilized in medical imaging, a field crucial for disease diagnosis and treatment planning. This is primarily due to the high computational cost associated with (1) the use of large number of time steps (e.g., 1,000) in diffusion processes and (2) the increased dimensionality of medical images, which are often 3D or 4D. Training a diffusion model on medical images typically takes days to weeks, while sampling each image volume takes minutes to hours. To address this challenge, we introduce Fast-DDPM, a simple yet effective approach capable of improving training speed, sampling speed, and generation quality simultaneously. Unlike DDPM, which trains the image denoiser across 1,000 time steps, Fast-DDPM trains and samples using only 10 time steps. The key to our method lies in aligning the training and sampling procedures. We introduced two efficient noise schedulers with 10 time steps: one with uniform time step sampling and another with non-uniform sampling. We evaluated Fast-DDPM across three medical image-to-image generation tasks: multi-image super-resolution, image denoising, and image-to-image translation. Fast-DDPM outperformed DDPM and current state-of-the-art methods based on convolutional networks and generative adversarial networks in all tasks. Additionally, Fast-DDPM reduced training time by a factor of 5 and sampling time by a factor of 100 compared to DDPM. Our code is publicly available at: https://github.com/mirthAI/Fast-DDPM.
Abstract:Similar to Vision Transformers, this paper identifies artifacts also present within the feature maps of Vision Mamba. These artifacts, corresponding to high-norm tokens emerging in low-information background areas of images, appear much more severe in Vision Mamba -- they exist prevalently even with the tiny-sized model and activate extensively across background regions. To mitigate this issue, we follow the prior solution of introducing register tokens into Vision Mamba. To better cope with Mamba blocks' uni-directional inference paradigm, two key modifications are introduced: 1) evenly inserting registers throughout the input token sequence, and 2) recycling registers for final decision predictions. We term this new architecture Mamba-R. Qualitative observations suggest, compared to vanilla Vision Mamba, Mamba-R's feature maps appear cleaner and more focused on semantically meaningful regions. Quantitatively, Mamba-R attains stronger performance and scales better. For example, on the ImageNet benchmark, our base-size Mamba-R attains 82.9% accuracy, significantly outperforming Vim-B's 81.8%; furthermore, we provide the first successful scaling to the large model size (i.e., with 341M parameters), attaining a competitive accuracy of 83.2% (84.5% if finetuned with 384x384 inputs). Additional validation on the downstream semantic segmentation task also supports Mamba-R's efficacy.
Abstract:Deep learning has become the de facto method for medical image segmentation, with 3D segmentation models excelling in capturing complex 3D structures and 2D models offering high computational efficiency. However, segmenting 2.5D images, which have high in-plane but low through-plane resolution, is a relatively unexplored challenge. While applying 2D models to individual slices of a 2.5D image is feasible, it fails to capture the spatial relationships between slices. On the other hand, 3D models face challenges such as resolution inconsistencies in 2.5D images, along with computational complexity and susceptibility to overfitting when trained with limited data. In this context, 2.5D models, which capture inter-slice correlations using only 2D neural networks, emerge as a promising solution due to their reduced computational demand and simplicity in implementation. In this paper, we introduce CSA-Net, a flexible 2.5D segmentation model capable of processing 2.5D images with an arbitrary number of slices through an innovative Cross-Slice Attention (CSA) module. This module uses the cross-slice attention mechanism to effectively capture 3D spatial information by learning long-range dependencies between the center slice (for segmentation) and its neighboring slices. Moreover, CSA-Net utilizes the self-attention mechanism to understand correlations among pixels within the center slice. We evaluated CSA-Net on three 2.5D segmentation tasks: (1) multi-class brain MRI segmentation, (2) binary prostate MRI segmentation, and (3) multi-class prostate MRI segmentation. CSA-Net outperformed leading 2D and 2.5D segmentation methods across all three tasks, demonstrating its efficacy and superiority. Our code is publicly available at https://github.com/mirthAI/CSA-Net.
Abstract:We introduce the RetinaRegNet model, which can achieve state-of-the-art performance across various retinal image registration tasks. RetinaRegNet does not require training on any retinal images. It begins by establishing point correspondences between two retinal images using image features derived from diffusion models. This process involves the selection of feature points from the moving image using the SIFT algorithm alongside random point sampling. For each selected feature point, a 2D correlation map is computed by assessing the similarity between the feature vector at that point and the feature vectors of all pixels in the fixed image. The pixel with the highest similarity score in the correlation map corresponds to the feature point in the moving image. To remove outliers in the estimated point correspondences, we first applied an inverse consistency constraint, followed by a transformation-based outlier detector. This method proved to outperform the widely used random sample consensus (RANSAC) outlier detector by a significant margin. To handle large deformations, we utilized a two-stage image registration framework. A homography transformation was used in the first stage and a more accurate third-order polynomial transformation was used in the second stage. The model's effectiveness was demonstrated across three retinal image datasets: color fundus images, fluorescein angiography images, and laser speckle flowgraphy images. RetinaRegNet outperformed current state-of-the-art methods in all three datasets. It was especially effective for registering image pairs with large displacement and scaling deformations. This innovation holds promise for various applications in retinal image analysis. Our code is publicly available at https://github.com/mirthAI/RetinaRegNet.
Abstract:This study introduces HQ-Edit, a high-quality instruction-based image editing dataset with around 200,000 edits. Unlike prior approaches relying on attribute guidance or human feedback on building datasets, we devise a scalable data collection pipeline leveraging advanced foundation models, namely GPT-4V and DALL-E 3. To ensure its high quality, diverse examples are first collected online, expanded, and then used to create high-quality diptychs featuring input and output images with detailed text prompts, followed by precise alignment ensured through post-processing. In addition, we propose two evaluation metrics, Alignment and Coherence, to quantitatively assess the quality of image edit pairs using GPT-4V. HQ-Edits high-resolution images, rich in detail and accompanied by comprehensive editing prompts, substantially enhance the capabilities of existing image editing models. For example, an HQ-Edit finetuned InstructPix2Pix can attain state-of-the-art image editing performance, even surpassing those models fine-tuned with human-annotated data. The project page is https://thefllood.github.io/HQEdit_web.